PREDNISONE


DrugBank ID: db00635
DrugCentral: prednisone
Synonymous :1,2-dehydrocortisone | 1,4-pregnadiene-17α,21-diol-3,11,20-trione | 17,21-dihydroxypregna-1,4-diene-3,11,20-trione | dehydrocortisone | prednisona | prednisone | prednisonum



Drug Sentece Context


Table 1. Analysis of context sentence of prednisone gene in 18 abstracts.

pmid sentence
32348046 Leur arrêt n’est recommandé qu’en cas d’infection avérée à SARS-CoV-2, à l’exception de la prednisone, de l’hydroxychloroquine et de la sulfasalazine qui peuvent être poursuivis.
32351040 Nine patients were on tacrolimus and a mycophenolic antimetabolite, and 70% were on prednisone.
32382516 She completed 5 days of hydroxychloroquine and 7 days of prednisone. […] It is unclear whether our institution’s empiric use of hydroxychloroquine and prednisone facilitated her recovery.
32400931 His maintenance immunosuppressive regime was consisted of tacrolimus (TAC, 1mg twice a day, orally), mycophenolate mofetil (MMF, 0.5g twice a day, orally) and prednisone (Pred, 5mg daily, orally) triple combination.
32419721 In summary, we recommend considering the discontinuation of oral JAK inhibitors and prednisone, considering the delay of rituximab infusion, and the careful continuation of cyclosporine, mycophenolate, azathioprine, methotrexate, and biologics in patients currently benefitting from such treatments.
32436948 We diagnosed SAT and the patient started prednisone.
32471903 In multivariable-adjusted models, prednisone dose ≥10 mg/day was associated with higher odds of hospitalisation (OR 2.05, 95% CI 1.06 to 3.96).
32573882 During hospitalization, calcineurin inhibitors and antimetabolites were held; prednisone was continued.
32583620 All five patients were on immunosuppressive therapy with mycophenolate mofetil (MMF) and tacrolimus and three that were transplanted within the prior two months were additionally on prednisone.
32646502 The aim of this study is to explore the effectiveness and safety of oral corticosteroids (prednisone) in the treatment of early stage SARS-Cov-2 pneumonia in patients who do not yet meet hospital admission criteria. […] Patients will be followed-up by specialist physicians and Primary Health Care professionals. - Men and women. - Age between 18 and 75 years old. - Diagnosed SARS-CoV-2 infection, by PCR and/or IgM+ antibody test and/or antigen test. - Clinical diagnosis of lung involvement: (respiratory symptoms +/- pathological auscultation +/- O2 desaturation) - Chest X-ray with mild-moderate alterations or normal. - Patients who give their verbal informed consent in front of witnesses, which will be reflected in the patients’ medical records. - Oxygen desaturation below 93% or P02 < 62. - Moderate-severe dyspnea or significant respiratory or general deterioration that makes admission advisable. - Chest X-ray with multifocal infiltrates. - Insulin-dependent diabetes with poor control or glycaemia in the emergency room test greater than 300 mg/ml (fasting or not). - Other significant comorbidities: Severe renal failure (creatinine clearance < 30 mL/min); cirrhosis or chronic liver disease, poorly controlled hypertension. - Heart rhythm disturbances (including prolonged QT). - Severe immunosuppression (HIV infection, long-term use of immunosuppressive agents); cancer. - Pregnant or breast-feeding women. - Patients under use of glucocorticoids for other diseases. - History of allergy or intolerance to any of the drugs in the study (prednisone, azithromycin or hydroxychloroquine). - Patients who took one or more of the study drugs in the 7 days prior to study inclusion. - Patients taking non-suppressible drugs with risk of QT prolongation or significant interactions. - Patients unwilling or unable to participate until study completion. - Participation in another study. […] Eligible patients will be randomized to receive standard outpatient treatment only (group 1) or standard outpatient treatment plus prednisone (group 2). - Group 1: paracetamol 1 g/8 h (on demand) + hydroxychloroquine 400 mg/12h the first day, 200 mg/12 h for 4 days + azithromycin 500 mg/24h for 5 days. - Group 2: paracetamol 1 g/8 h (on demand) + hydroxychloroquine 400 mg/12h the first day, 200 mg/12 h for 4 days + azithromycin 500 mg/24h for 5 days + prednisone 60 mg / 24 h for 3 days, 30 mg / 24 h for 3 days and 15 mg / 24 h for 3 days.
32676935 All findings were consistent with SAT, and treatment with oral prednisone (25 mg/day as the starting dose, gradually tapered) was started.
32692733 After finishing steroid treatment at home, the patient was readmitted with another episode of AIP complicated by development of acute necrotic collection and COVID-19 while taking a second course of high dose prednisone. […] The patient was continued on high dose prednisone, started on azathioprine and intravenous meropenem, and underwent CT guided percutaneous drainage.
32703929 Kidney transplant patients encountered COVID-19 were maintained on tacrolimus (Tac, 92%), mycophenolate mofetil (MMF, 78.8%), and prednisone (Pred, 77%) and were manage by holding MMF in 79.1% of patients and holding Tac in 34.4% of patients.
32760619 She was then treated with oral prednisone and subsequently discharged home after a prolonged course of eight days.
32780854 Symptoms disappeared a few days after commencement of treatment (prednisone in 3 patients and ibuprofen in 1).
32843098 Patients under chronic treatment with glucocorticoids for other diseases (≥ 8 mg prednisone, or equivalent) Participation in another randomized clinical trial.
32907638 Documented interstitial pneumonia requiring admission and at least two of the following parameters: 1) Fever ≥ 37.8°C (tympanic) 2) IL-6 in serum ≥ 25 pg/mL (in the absence of a previous dose of prednisone or equivalent> 1 mg / kg) or PCR> 5mg/dL 3) Lymphocytes <600 cells/mm3 4) Ferritin> 300 μg/L that doubles in 24 hours 5) Ferritin> 600 μg/L in the first determination and LDH> 250 U/L 6) D-dimer (> 1 mg/L) d.
32910433 The patient was treated with a tapered prednisone dose with resolution of his diplopia but no change in Adie’s pupil.
32924059 Intravenous gammaglobulin (78.1%) and methylprednisolone/prednisone(57.6%) were the most common therapeutic interventions ; immunomodulation was used in 24.3% of cases.
32943115 This exclusion category comprises: a) subjects with known infection by the human immunodeficiency virus (HIV-1) b) subjects with solid organ transplantation c) subjects with bone marrow transplantation d) subjects under chemotherapy e) subjects with primary immunodeficiency f) subjects under treatment with any anti-cytokine therapy within the last year g) subjects under treatment with oral or intravenous steroids defined as daily doses of 10 mg prednisone or equivalent for longer than 3 months h) Active solid or non-solid malignancy or lymphoma within the prior two years Direct involvement in the design or the execution of the BCG-DENMARK-COVID trial Intervention and comparator: Participants will be randomised to BCG vaccine (BCG-Denmark, AJ Vaccines, Copenhagen, Denmark) or placebo (saline).
32961675 There were five corticosteroid regimens, which used dexamethasone, methylprednisolone, or prednisone, with different doses and treatment durations.
32971254 The main exposure variable was corticosteroid therapy at a dose of ≥0.5 mg/kg of prednisone equivalents.
32974243 He responded well to standard-dose prednisone treatment for nephrotic syndrome. […] At 1 week after starting the prednisone treatment, he went into clinical remission. […] The patient responded well to the standard-dose prednisone treatment that is typically used for new-onset nephrotic syndrome.
32979013 Patient received standard prednisone and tacrolimus-based immunosuppression without induction therapy following transplant.
32984404 High-risk factors for COVID-19 complications, i.e., high-dose steroids (40 mg prednisone) and severe active disease, were present at admission.
32997868 He was diagnosed with right peripheral facial palsy and was treated with prednisone 60 mg/24h with a tapering schedule.
33011038 Oral prednisone therapy (5 mg) was initiated and the patient was discharged on a continued prednisone taper.
33041077 The large proportion of infected individuals were minorities (Hispanic 65.9%, black 14.6%), on prednisone, tacrolimus, and mycophenolate mofetil (95.1%, 87.8%, and 87.8%, respectively), and had excellent allograft function (median 1.25 mg/dL).
33048372 We compared three groups based on immunosuppression regimen 7-12 months posttransplant: 1) tacrolimus (Tac)+mycophenolic acid (MPA)+prednisone (Pred) (referent group, 77.7%); 2) Tac+MPA+Pred+HCQ (16.5%); or 3) other immunosuppression+HCQ (5.7%).