PREDNISOLONE


DrugBank ID: db00860
DrugCentral: prednisolone
Synonymous :(11β)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione | 1,4-pregnadiene-11β,17α,21-triol-3,20-dione | 1,4-pregnadiene-3,20-dione-11β,17α,21-triol | 3,20-dioxo-11β,17α,21-trihydroxy-1,4-pregnadiene | delta-dehydrocortisol | delta-dehydrohydrocortisone | delta-hydrocortisone | delta(1)-dehydrocortisol | delta(1)-dehydrohydrocortisone | delta(1)-hydrocortisone | hydroretrocortine | metacortandralone | prdl | prednisolona | prednisolone | prednisolonum



Drug Sentece Context


Table 1. Analysis of context sentence of prednisolone gene in 18 abstracts.

pmid sentence
32256705 Low-dose prednisolone and tacrolimus may have beneficial impacts on COVID-19.
32363963 He was receiving mycophenolate mofetil (MMF) for one month and 30 mg prednisolone for three months until his hospitalization. […] Prednisolone was tapered to 15 mg when current COVID-19 was suspected, considering his recent cough, dyspnea, and fever.
32379699 We also comment on suggested dosing for patients who usually take modified release hydrocortisone or prednisolone.
32476308 A proper combination of antiviral agents, immune modulators such as prednisolone, and anticoagulants such as heparin and anti-C5a antagonists could be employed to minimize lung damage and prevent systemic involvements.
32493514 Immunosuppressive therapy (e.g. mycophenolate, azathioprine, methotrexate, biologicals, prednisolone >10mg/d; exceptions are: prednisolone ≤ 10mg/d, sulfasalazine or hydroxychloroquine)9.
32526068 There was no association between prednisolone dose and concern.
32541245 CD4 and CD8 T cells frequencies decreased because of prednisolone, followed by a plateauing increase whereas CD19CD20 B cell increased strongly and was unaffected by COVID-19 infection. […] Although activated Tregs (CD4CD45RAFOXP3) strongly increased upon prednisolone, it decreased afterwards. […] Furthermore, regulatory B cells (Bregs: CD19CD20CD24CD38) declined sharply owing to prednisolone. […] We hypothesize that continuing with low level of prednisolone without azathioprine may have abrogated activated Tregs, Bregs and IL-6 production and therefore permitting the activation of CD8 T cells, clearing the virus.
32562159 According to the drug regimen, the patients were divided into two groups; group I who received regimen I consisting azithromycin, prednisolone, naproxen, and lopinavir/ritonavir and group II who received regimen II including meropenem, levofloxacin, vancomycin, hydroxychloroquine, and oseltamivir. […] This study revealed the beneficial effect of the short-term use of low-dose prednisolone in combination with azithromycin, naproxen and lopinavir/ritonavir (regimen I), in decreasing ALOS compared to regimen II.
32573355 In addition to the selected compounds, 4 nucleoside analogs of anti-viral (Raltgravir, Maraviroc and Favipiravir) and anti-inflammatory (Prednisolone) drugs were selected for further investigations.
32585765 A 58-year-old 2 years post kidney transplant recipient, with maintenance immunosuppression of tacrolimus, mycophenolate mofetil (MMF) and prednisolone, presented with acute diarrhea which followed by fever on day 12.
32591970 Substantial clinical improvement was obtained following a management plan, which included tocilizumab, hydroxychloroquine, prednisolone and enoxaparin sodium.
32681756 We decreased the dose of immunosuppression and started stress dose of intravenous hydrocortisone or equivalent oral prednisolone.
32690572 The patient was admitted for 1 day; immunosuppressive therapy with tacrolimus and low-dose prednisolone was continued; and the patient recovered successfully without the use of antiviral agents or oxygen therapy.
32715804 She received lopinavir/ritonavir and azithromycin as well as early methyl prednisolone therapy.
32760206 Hydrocortisone showed the strongest effect on ACE2 activation, followed by prednisolone, dexamethasone, and methylprednisolone.
32763890 For patients diagnosed most recently, there was evidence of more rapid initial prescribing of corticosteroids (prednisolone) and earlier referral for NMR therapy.
32843231 Patients had previously received combinations of azithromycin, hydroxy-chloroquine, and methyl-prednisolone.
32868989 He received 30 mg prednisolone for five days with antiviral drug of favipiravir, and was successfully extubated on day five.
32879154 A 69-year-old woman with lymphoma-type ATL was treated using cyclophosphamide, doxorubicin, vincristine, prednisolone and mogamulizumab (M-CHOP) with substantial efficacy.
32960899 To analyze the effects of a short course of methyl-prednisolone pulses (MP) during the second week of disease (week-2) in patients with severe coronavirus disease 2019 (COVID-19) pneumonia.
32983161 With only few case studies published on SARS-CoV-2 infection in patients with rheumatic diseases, we report a 25-year-old male who developed moderate coronavirus disease 2019 (COVID-19) with fever, mild dyspnea, and no major complications despite having received high-dose prednisolone, cyclophosphamide, and rituximab for the treatment of highly active, life-threatening eosinophilic granulomatosis with polyangiitis (EGPA).
32986289 Low dose prednisolone should be considered on an individualized basis.
33043249 We present a case of a patient previously considered recovered from nosocomially transmitted asymptomatic COVID-19 illness, who presented with new respiratory, radiological, and RT-PCR findings consistent with COVID-19, while on high-dose prednisolone due to a suspected secondary demyelinating disease.