PREDNISOLONE
DrugBank ID: db00860
DrugCentral: prednisolone
Synonymous :(11β)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione | 1,4-pregnadiene-11β,17α,21-triol-3,20-dione | 1,4-pregnadiene-3,20-dione-11β,17α,21-triol | 3,20-dioxo-11β,17α,21-trihydroxy-1,4-pregnadiene | delta-dehydrocortisol | delta-dehydrohydrocortisone | delta-hydrocortisone | delta(1)-dehydrocortisol | delta(1)-dehydrohydrocortisone | delta(1)-hydrocortisone | hydroretrocortine | metacortandralone | prdl | prednisolona | prednisolone | prednisolonum
Drug Sentece Context
Table 1. Analysis of context sentence of prednisolone gene in 18 abstracts.
pmid | sentence |
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32256705 | Low-dose prednisolone and tacrolimus may have beneficial impacts on COVID-19. |
32363963 | He was receiving mycophenolate mofetil (MMF) for one month and 30 mg prednisolone for three months until his hospitalization. […] Prednisolone was tapered to 15 mg when current COVID-19 was suspected, considering his recent cough, dyspnea, and fever. |
32379699 | We also comment on suggested dosing for patients who usually take modified release hydrocortisone or prednisolone. |
32476308 | A proper combination of antiviral agents, immune modulators such as prednisolone, and anticoagulants such as heparin and anti-C5a antagonists could be employed to minimize lung damage and prevent systemic involvements. |
32493514 | Immunosuppressive therapy (e.g. mycophenolate, azathioprine, methotrexate, biologicals, prednisolone >10mg/d; exceptions are: prednisolone ≤ 10mg/d, sulfasalazine or hydroxychloroquine)9. |
32526068 | There was no association between prednisolone dose and concern. |
32541245 | CD4 and CD8 T cells frequencies decreased because of prednisolone, followed by a plateauing increase whereas CD19CD20 B cell increased strongly and was unaffected by COVID-19 infection. […] Although activated Tregs (CD4CD45RAFOXP3) strongly increased upon prednisolone, it decreased afterwards. […] Furthermore, regulatory B cells (Bregs: CD19CD20CD24CD38) declined sharply owing to prednisolone. […] We hypothesize that continuing with low level of prednisolone without azathioprine may have abrogated activated Tregs, Bregs and IL-6 production and therefore permitting the activation of CD8 T cells, clearing the virus. |
32562159 | According to the drug regimen, the patients were divided into two groups; group I who received regimen I consisting azithromycin, prednisolone, naproxen, and lopinavir/ritonavir and group II who received regimen II including meropenem, levofloxacin, vancomycin, hydroxychloroquine, and oseltamivir. […] This study revealed the beneficial effect of the short-term use of low-dose prednisolone in combination with azithromycin, naproxen and lopinavir/ritonavir (regimen I), in decreasing ALOS compared to regimen II. |
32573355 | In addition to the selected compounds, 4 nucleoside analogs of anti-viral (Raltgravir, Maraviroc and Favipiravir) and anti-inflammatory (Prednisolone) drugs were selected for further investigations. |
32585765 | A 58-year-old 2 years post kidney transplant recipient, with maintenance immunosuppression of tacrolimus, mycophenolate mofetil (MMF) and prednisolone, presented with acute diarrhea which followed by fever on day 12. |
32591970 | Substantial clinical improvement was obtained following a management plan, which included tocilizumab, hydroxychloroquine, prednisolone and enoxaparin sodium. |
32681756 | We decreased the dose of immunosuppression and started stress dose of intravenous hydrocortisone or equivalent oral prednisolone. |
32690572 | The patient was admitted for 1 day; immunosuppressive therapy with tacrolimus and low-dose prednisolone was continued; and the patient recovered successfully without the use of antiviral agents or oxygen therapy. |
32715804 | She received lopinavir/ritonavir and azithromycin as well as early methyl prednisolone therapy. |
32760206 | Hydrocortisone showed the strongest effect on ACE2 activation, followed by prednisolone, dexamethasone, and methylprednisolone. |
32763890 | For patients diagnosed most recently, there was evidence of more rapid initial prescribing of corticosteroids (prednisolone) and earlier referral for NMR therapy. |
32843231 | Patients had previously received combinations of azithromycin, hydroxy-chloroquine, and methyl-prednisolone. |
32868989 | He received 30 mg prednisolone for five days with antiviral drug of favipiravir, and was successfully extubated on day five. |
32879154 | A 69-year-old woman with lymphoma-type ATL was treated using cyclophosphamide, doxorubicin, vincristine, prednisolone and mogamulizumab (M-CHOP) with substantial efficacy. |
32960899 | To analyze the effects of a short course of methyl-prednisolone pulses (MP) during the second week of disease (week-2) in patients with severe coronavirus disease 2019 (COVID-19) pneumonia. |
32983161 | With only few case studies published on SARS-CoV-2 infection in patients with rheumatic diseases, we report a 25-year-old male who developed moderate coronavirus disease 2019 (COVID-19) with fever, mild dyspnea, and no major complications despite having received high-dose prednisolone, cyclophosphamide, and rituximab for the treatment of highly active, life-threatening eosinophilic granulomatosis with polyangiitis (EGPA). |
32986289 | Low dose prednisolone should be considered on an individualized basis. |
33043249 | We present a case of a patient previously considered recovered from nosocomially transmitted asymptomatic COVID-19 illness, who presented with new respiratory, radiological, and RT-PCR findings consistent with COVID-19, while on high-dose prednisolone due to a suspected secondary demyelinating disease. |