PRAVASTATIN
DrugBank ID: db00175
DrugCentral: pravastatin
Synonymous :(+)-(3r,5r)-3,5-dihydroxy-7-[(1s,2s,6s,8s,8ar)-6-hydroxy-2-methyl-8-{[(s)-2-methylbutyryl]oxy}-1,2,6,7,8,8a-hexahydro-1-naphthyl]heptanoic acid | pravastatin | pravastatin acid | pravastatina | pravastatine | pravastatinum
Drug Sentece Context
Table 1. Analysis of context sentence of pravastatin gene in 3 abstracts.
| pmid | sentence |
|---|---|
| 32399094 | The binding energies obtained from the docking of 6LU7 with native ligand favipiravir, nelfinavir, lopinavir, simvastatin, rosuvastatin, pravastatin, pitavastatin, lovastatin, fluvastatin, and atorvastatin were -6.8, -5.8, -7.9, -7.9, -7.0, -7.7, -6.6, -8.2, -7.4, -7.7, and -6.8 kcal/mol, respectively. […] The number of hydrogen bonds between statins and amino acid residues of Mpro were 7, 4, and 3 for rosuvastatin, pravastatin, and atorvastatin, respectively, while other statins had two hydrogen bonds. |
| 33437096 | Electrophysiological studies performed in our laboratory showed that statins: pravastatin, mevastatin and simvastatin are effective inhibitors of Kv1.3 channels in cancer cells of human T cell line Jurkat. […] The inhibitory effect was the most potent in case of simvastatin and the least potent in case of pravastatin. […] The inhibition was partially irreversible in case of simvastatin and fully reversible in case of pravastatin and mevastatin. |