PRALATREXATE


DrugBank ID: db06813
DrugCentral: pralatrexate
Synonymous :(2s)-2-((4-((1rs)-1-((2,4-diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid | (2s)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid | 10-propargyl-10-deazaaminopterin | n-(4-(1-((2,4-diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-l-glutamic acid | pdx | pralatrexate | pralatrexato | pralatrexatum



Drug Sentece Context


Table 1. Analysis of context sentence of pralatrexate gene in 2 abstracts.

pmid sentence
33382685 Among the four selected market available drug candidates, Pralatrexate and Azithromycin were confirmed to effectively inhibit SARS-CoV-2 replication in vitro with EC50 values of 0.008μM and 9.453 μM, respectively. […] For the first time, our study discovered that Pralatrexate is able to potently inhibit SARS-CoV-2 replication with a stronger inhibitory activity than Remdesivir within the same experimental conditions.