PEMBROLIZUMAB
DrugBank ID: db09037
DrugCentral: pembrolizumab
Synonymous :lambrolizumab
Drug Sentece Context
Table 1. Analysis of context sentence of pembrolizumab gene in 7 abstracts.
| pmid | sentence |
|---|---|
| 32669298 | The main treatment choice in fit, favourable risk patients outside the pandemic is pembrolizumab/axitinib for 53%, avelumab/axitinib, sunitinib or pazopanib for 13% of experts each. |
| 32714874 | Food and Drug Administration (FDA) granted accelerated approval for extended-interval strategy of pembrolizumab at a dose of 400 mg every 6 weeks for all already approved oncologic indications. |
| 32788235 | From a total of 14 MSI-H metastatic prostate cancer patients at participating centers, nine patients with mCRPC with 56% bone, 33% nodal, 11% liver and 11% soft-tissue metastases and a median PSA of 29.3 ng/dL, were treated with pembrolizumab after 2 lines of therapy for CRPC. […] The estimated median time on pembrolizumab was 9.9 (95% CI 1.0 to 18.8) months. […] At time of cut-off, four patients were still on pembrolizumab while four patients discontinued therapy due to progressive disease and one due to COVID-19 infection. […] The robust activity of pembrolizumab in selected patients supports the generalized testing for MSI-H. |
| 32900245 | Here we describe a metastatic Merkel cell carcinoma patient with a severe acute respiratory syndrome coronavirus 2 infection while receiving pembrolizumab. […] Case presentation: A 66-year-old man, with a metastatic Merkel cell carcinoma receiving pembrolizumab, presented with fever. |