DrugBank ID: db13048
DrugCentral: pac-1
Synonymous : None

Drug Sentece Context

Table 1. Analysis of context sentence of pac-1 gene in 1 abstracts.

pmid sentence
32887634 SARS-CoV-2 and its Spike protein directly enhanced platelet activation such as platelet aggregation, PAC-1 binding, CD62P expression, α granule secretion, dense granule release, platelet spreading, and clot retraction in vitro, and thereby Spike protein enhanced thrombosis formation in wild-type mice transfused with hACE2 transgenic platelets, but this was not observed in animals transfused with wild-type platelets in vivo.