PAC-1
DrugBank ID: db13048
DrugCentral: pac-1
Synonymous : None
Drug Sentece Context
Table 1. Analysis of context sentence of pac-1 gene in 2 abstracts.
| pmid | sentence |
|---|---|
| 32887634 | SARS-CoV-2 and its Spike protein directly enhanced platelet activation such as platelet aggregation, PAC-1 binding, CD62P expression, α granule secretion, dense granule release, platelet spreading, and clot retraction in vitro, and thereby Spike protein enhanced thrombosis formation in wild-type mice transfused with hACE2 transgenic platelets, but this was not observed in animals transfused with wild-type platelets in vivo. |
| 33153161 | We also study the structure of platelets and erythrocytes using fluorescence microscopy (using the markers PAC-1 and CD62PE) and scanning electron microscopy. |