OXYPURINOL

Drug Sentece Context

Table 1. Analysis of context sentence of oxypurinol gene in 1 abstracts.

pmid	sentence
32787748	We have previously described that pentoxifylline alone, or in combination with oxypurinol, reduces the systemic inflammation caused by experimentally-induced pancreatitis in rats. […] Pentoxifylline is an inhibitor of TNF-α production and oxypurinol inhibits xanthine oxidase. […] Therefore, it may be hypothesized that early treatment of COVID-19 patients with pentoxifylline, alone or in combination with oxypurinol, would prevent the potentially lethal acute respiratory distress syndrome. […] Pentoxifylline and oxypurinol are licensed drugs used for diseases other than COVID-19 and, therefore, phase I clinical trials would not be necessary for the administration to SARS-CoV-2- infected people.