NOREPINEPHRINE


DrugBank ID: db00368
DrugCentral: norepinephrine
Synonymous :(−)-arterenol | (−)-noradrenaline | (−)-norepinephrine | (r)-(−)-norepinephrine | (r)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol | (r)-noradrenaline | (r)-norepinephrine | 4-[(1r)-2-amino-1-hydroxyethyl]-1,2-benzenediol | arterenol | l-noradrenaline | l-norepinephrine | nor-adrenaline | noradrenaline | norepinefrina | norépinéphrine | norepinephrine | norepinephrinum



Drug Sentece Context


Table 1. Analysis of context sentence of norepinephrine gene in 8 abstracts.

pmid sentence
32488505 All children but one needed an inotropic/vasoactive drug support (epinephrine, n = 12; milrinone, n = 10; dobutamine, n = 6, norepinephrine, n = 4) and 8 were intubated.
32495913 At admission, the patient was hemodynamically unstable requiring circulatory support with liquids and norepinephrine; laboratory tests showed disseminated intravascular coagulation (DIC).
32586396 All patients aged 18- 80 with positive polymerase chain reaction (PCR) test for SARS-CoV-2, a C-reactive protein (CRP) ≥ 100 mg/l, a Procalcitonin (PCT) < 2 ng/l, and suspected cytokine storm defined via a vasoplegic shock (Norepinephrine > 0.2 μg/min/kg to achieve a Mean Arterial Pressure ≥ 65mmHg).
32680896 Undifferentiated shock may be treated initially with norepinephrine to optimize perfusion while additional evaluation is performed to categorize the shock pathophysiology.
32838394 Forty-eight (42%) patients were hypotensive and required norepinephrine immediately post-intubation.
32957066 Most often reported cortisol represents the currently best evaluated stress marker, while norepinephrine (noradrenaline) or its metabolite 3-methoxy-4-hydroxyphenylglycol is also a quite commonly considered stress marker.
33031192 The hemodynamic response to angiotensin II was estimated by recording the mean arterial pressure, norepinephrine equivalent dose (NED) and urine output. […] Over the initial 6 hours, the average the norepinephrine equivalent dose decreased by 30.4% (from 64.6 mcg/min to 44 mcg/min) without a significant change in the mean arterial pressure (0.7% decrease). […] Six patients experienced at least a 25% reduction in norepinephrine equivalent dose by 6 hours, and two experienced at least a 50% reduction.