Drug Sentece Context
Table 1. Analysis of context sentence of natalizumab gene in 3 abstracts.
|32388451||Development of PML or other serious opportunistic infections during treatment with natalizumab forces to consider whether de-risking strategies are needed in this particular context and how to manage a high-efficacy treatment. […] In this paper we report on a patient treated with natalizumab for relapsing MS who developed COVID-19 and recovered in a few days without complications. […] After recovery natalizumab has been administered in the window of the extended interval dosing (EID), without reporting any worsening or new symptoms.|
|32531754||Natalizumab, approved for Multiple Sclerosis (MS) treatment, acts blocking α4-integrin. […] We report a MS patient treated with natalizumab who develops COVID-19, with excellent recovery and repeated negative results in 5 consecutive microbiological studies. […] We postulate this may be due to the blockade of integrins induced by natalizumab.|
|32590314||Platform therapies, dimethyl-fumarate and natalizumab are considered safe options to initiate in naive patients. decision-making about MS and NMOSD patients has become even more complex in order to adapt to the COVID-19 pandemic.|