MORPHINE


DrugBank ID: db00295
DrugCentral: morphine
Synonymous :(−)-morphine | (5alpha,6alpha)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol | (5alpha,6alpha)-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol | (5r,6s,9r,13s,14r)-4,5-epoxy-n-methyl-7-morphinen-3,6-diol | (5α,6α)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol | (5α,6α)-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol | (7r,7as,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1h-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol | anhydrous morphine | morfina | morphia | morphin | morphine | morphinum | morphium



Drug Sentece Context


Table 1. Analysis of context sentence of morphine gene in 2 abstracts.

pmid sentence
32133829 Midazolam, Propofol and Morphine or fentanyl were used for sedation and analgesia, avoiding patients cough and agitated during the procedure.
32293020 Based on the evidence to date, there are several treatment options to consider for the relief of fever (acetaminophen, NSAID, oral glucocorticoids), cough (morphine), breathlessness (morphine, oxygen, fan), anxiety (benzodiazepines) and pain (NSAID, morphine).
32325167 Frequently used medicines (median [range] dose/24 hours) were opioids (morphine, 10 [5-30] mg; fentanyl, 100 [100-200] mcg; alfentanil, 500 [150-1000] mcg) and midazolam (10 [5-20] mg).
32387575 Frequently used medicines include opioids such as morphine or fentanyl and midazolam, all of them listed as ICEMs.
32428864 In this view, we highlighted potential approaches to address ACE2-mediated SARS-CoV-2 virus, including 1) delivering an excessive soluble form of ACE2 (recombinant human ACE2: rhACE2) and 2) inhibition of the interaction between SARS-CoV-2 virus and ACE2 by some compounds with competitive effects (morphine and codeine).
32588748 Mean total opioid dose required in the last 24 h of life was 14 mg morphine subcutaneous equivalent, and mean total midazolam dose was 9.5 mg.
32705889 Sixty percent of patients needed a continuous subcutaneous infusion and the median morphine dose was 10 mg S/C per 24 hours and midazolam 10 mg S/C per 24 hours. […] The majority of patients had symptoms controlled with low doses of morphine and midazolam, and death was rapid.
32736493 Sixty-one patients met the audit criteria: the commonest problem was shortness of breath (57.5%), which was generally controlled with conservative doses of morphine (10-20 mg/24 h via a syringe pump).