LEUCOVORIN


DrugBank ID: db00650
DrugCentral: leucovorin
Synonymous :(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate | 10-formyl-7,8-dihydrofolic acid | 5-formyl-5,6,7,8-tetrahydrofolic acid | 5-formyl-5,6,7,8-tetrahydropteroyl-l-glutamic acid | 5-formyltetrahydrofolate | 5-formyltetrahydrofolic acid | acide folinique | acido folinico | folinate | folinic acid | l(-)-5-formyl-5,6,7,8-tetrahydrofolic acid | leucovorinum | n-(5-formyl-5,6,7,8-tetrahydropteroyl)-l-glutamic acid | n5-formyl-5,6,7,8-tetrahydrofolic acid | n5-formyltetrahydrofolic acid



Drug Sentece Context


Table 1. Analysis of context sentence of leucovorin gene in 3 abstracts.

pmid sentence
32534807 We propose as a putative randomized controlled trial that high-dose methotrexate with leucovorin (HDMTX-LR) rescue can abolish ‘PANIC’, thereby ‘left-shifting’ severe COVID-19 patients to the group majority of those infected with SARS-CoV-2, who are designated as having mild, even asymptomatic, disease.
32815481 Mitoxantrone and Leucovorin from FDA approved drug library and Birinapant and Dynasore from anti-viral drug libraries interact with SARS-CoV-2 Mpro at higher efficiency as a result of the improved steric and hydrophobic environment in the binding cavity to make stable complex. […] Our findings suggest that Mitoxantrone, Leucovorin, Birinapant, and Dynasore represents potential inhibitors of SARS-CoV-2 Mpro.