LENTINAN
DrugBank ID: db13480
DrugCentral: lentinan
Synonymous : None
Drug Sentece Context
Table 1. Analysis of context sentence of lentinan gene in 5 abstracts.
| pmid | sentence |
|---|---|
| 32413619 | Specifically, the impact on the immunomodulatory and cytoprotective properties of our novel in ‘house’ (IH-Lentinan, IHL) and a commercial (Carbosynth-Lentinan, CL) Lentinan extract were investigated using in vitro models of lung injury and macrophage phagocytosis. […] The two lentinan extracts demonstrated varying immunomodulatory activities. […] Both Lentinan extracts reduced cytokine-induced NF-κB activation in human alveolar epithelial A549 cells, with the IHL extract proving more effective at lower doses. […] Our findings demonstrate significant physicochemical differences between Lentinan extracts, which produce differential in vitro immunomodulatory and pulmonary cytoprotective effects that may also have positive relevance to candidate COVID-19 therapeutics targeting cytokine storm. |