KIFUNENSINE
DrugBank ID: db02742
DrugCentral: kifunensine
Synonymous : None
Drug Sentece Context
Table 1. Analysis of context sentence of kifunensine gene in 1 abstracts.
| pmid | sentence |
|---|---|
| 33094291 | Unfolded protein response (UPR) suppression by Kifunensine has been associated with lung hyperpermeability, the hallmark of Acute Respiratory Distress Syndrome. […] The present study investigates the effects of the heat shock protein 90 inhibitor Luminespib (AUY-922) towards the Kifunensine-triggered lung endothelial dysfunction. […] Our results indicate that the UPR inducer Luminespib counteracts the effects of Kifunensine in both human and bovine lung endothelial cells. |
| 33103998 | Blocking N-glycan biosynthesis at the oligomannose stage using both genetic approaches and the small molecule kifunensine dramatically reduced viral entry into ACE2 expressing HEK293T cells. |