ISOLEUCINE
DrugBank ID: db00167
DrugCentral: isoleucine
Synonymous :(2s,3s)-2-amino-3-methylpentanoic acid | 2-amino-3-methylvaleric acid | alpha-amino-beta-methylvaleric acid | ile | isoleucina | isoleucine | isoleucinum | l-isoleucine | α-amino-β-methylvaleric acid
Drug Sentece Context
Table 1. Analysis of context sentence of isoleucine gene in 1 abstracts.
pmid | sentence |
---|---|
32083328 | Position 723 in the COVID-2019 has a serine instead a glycine residue, while at aminoacidic position 1010 a proline instead an isoleucine. |
32378705 | At this site, arginine (a positively charged amino acid) was replaced by isoleucine (a hydrophobic amino acid that is also a C-β branched amino acid). |
32488835 | Through this paper, we provided the list of possible chemical ligands (Meglumine, Vidarabine, Adenosine, D-Sorbitol, D-Mannitol, Sodium_gluconate, Ganciclovir and Chlorobutanol) and peptide drugs (combination of isoleucine, lysine and proline) from the databases to guide the experimental scientists and validate the molecules which can combat the virus in a shorter time. |
33453245 | Pathway and network enrichment analyses revealed that the 92 DEPs were mostly associated with metabolic, complement and coagulation cascades, lysosome, and cholesterol metabolism pathways, and the 375 COVID-19 only proteins were mainly enriched in amino acid degradation (Valine, Leucine and Isoleucine degradation), amino acid metabolism (beta-Alanine, Tryptophan, Cysteine and Methionine metabolism), oxidative phosphorylation, phagosome, and cholesterol metabolism pathways. |