IMIQUIMOD
DrugBank ID: db00724
DrugCentral: imiquimod
Synonymous :1-isobutyl-1h-imidazo[4,5-c]quinolin-4-amine | 4-amino-1-isobutyl-1h-imidazo(4,5-c)quinoline | imiquimod | imiquimodum
Drug Sentece Context
Table 1. Analysis of context sentence of imiquimod gene in 1 abstracts.
| pmid | sentence |
|---|---|
| 32599245 | We have identified significant interaction between ISGs and TLR3 agonists, like poly I: C, and imiquimod, and suggests that TLR3 agonists can be considered as a potential drug for drug repurposing in COVID-19. |
| 32706371 | In primary peripheral blood mononuclear cells from the patients, downstream type I interferon (IFN) signaling was transcriptionally downregulated, as measured by significantly decreased mRNA expression of IRF7, IFNB1, and ISG15 on stimulation with the TLR7 agonist imiquimod as compared with family members and controls. […] The production of IFN-γ, a type II IFN, was decreased in patients in response to stimulation with imiquimod. |
| 32846644 | Imiquimod is an immune-stimulator that activates TLR 7 and can be used to enhance the innate and adaptive immunity. |
| 33458805 | We present a male patient who had two melanoma-in-situs (MISs) that were treated during the COVID-19 pandemic with a combination of topical imiquimod 5% cream, 5-fluorouracil 2% solution, and tretinoin 0.1% cream. |