DrugBank ID: db01005
DrugCentral: hydroxyurea
Synonymous :carbamohydroxamic acid | carbamohydroximic acid | carbamoyl oxime | carbamyl hydroxamate | hidroxicarbamida | hydrea | hydroxycarbamid | hydroxycarbamide | hydroxycarbamidum | hydroxyharnstoff | hydroxyurea | n-carbamoylhydroxylamine | n-hydroxyurea | oxyurea

Drug Sentece Context

Table 1. Analysis of context sentence of hydroxyurea gene in 9 abstracts.

pmid sentence
32873056 Hydroxyurea has been the cornerstone of management in children and adults with SCD, with evidence of its effect on controlling end organ damage.
32893954 Hydroxyurea use (P-value = .02) and lower absolute monocyte counts (P-value = .04) were noted in patients who did not develop ACS.
32908840 We report the case of a 50-year-old patient with acute COVID-19 pneumonia, who had iatrogenic, clinically relevant bone marrow suppression due to accidental overdose with hydroxyurea, and decreased lung capacity due to a left-sided pneumonectomy 6 months earlier. […] Symptomatic treatment with oxygen supplementation and pulmonary physical therapy was initiated, and hydroxyurea was discontinued.
32952617 In fact, there are other immunosuppressants known with antiviral activities, including cyclosporine A, hydroxyurea, minocycline, mycophenolic acid, mycophenolate mofetil, leflunomide, tofacitinib, and thalidomide.
33043250 She continued taking hydroxyurea and aspirin for her treatment of polycythemia vera.
33114733 Ruxolitinib (RUX), a JAK1/JAK2 inhibitor, is approved for second-line therapy in patients with polycythemia vera (PV) who are resistant or intolerant to hydroxyurea.
33570644 All deaths occurred in individuals not taking hydroxyurea or any other SCD-modifying therapy. […] Individuals with SCD aged >50 years, with preexisting cardiopulmonary, renal disease, and/or stroke not receiving hydroxyurea, who present with high serum creatinine, lactate dehydrogenase, and D-dimer levels, are at higher risk of death, irrespective of genotype or sex.