HYDROCORTISONE


DrugBank ID: db00741
DrugCentral: hydrocortisone
Synonymous :(11β)-11,17,21-trihydroxypregn-4-ene-3,20-dione | 11beta-hydrocortisone | 11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione | 11β-hydrocortisone | 17-hydroxycorticosterone | 4-pregnen-11β,17α,21-triol-3,20-dione | cortisol | hidrocortisona | hydrocortisone | hydrocortisonum | kendall’s compound f | reichstein’s substance m



Drug Sentece Context


Table 1. Analysis of context sentence of hydrocortisone gene in 5 abstracts.

pmid sentence
32379699 In patients with adrenal insufficiency developing an acute COVID-19 infection, which frequently presents with continuous high fever, we suggest oral stress dose cover with 20mg hydrocortisone every six hours. […] We also comment on suggested dosing for patients who usually take modified release hydrocortisone or prednisolone. […] In patients with clinical insufficiency showing clinical deterioration during an acute COVID-19 infection, we advise immediate (self-)injection of 100mg hydrocortisone intramuscularly, followed by continuous intravenous infusion of 200mg hydrocortisone per 24 hours, or until this can be established, administration of 50mg hydrocortisone every 6 hours.
32400099 Therefore, the immunosuppressive medications were discontinued, and hydrocortisone started.
32513653 As per BSG guidance, intravenous hydrocortisone was considered appropriate as initial management; only in patients with COVID-19 pneumonia was its use deemed uncertain.
32537482 Hydrocortisone (DB00741) (previously used for SARS-CoV-1 and MERS) and Dinoprost-tromethamine (DB01160) from DrugBank.
32555949 In the presence of any emergency warning signs or inability to administer oral GC doses, we recommend that patients should immediately seek Emergency services to evaluate COVID-19 symptoms and receive 100 mg hydrocortisone by intravenous injection, followed by 50 mg hydrocortisone intravenously every 6 h or 200 mg/day by continuous intravenous infusion.