HISTIDINE


DrugBank ID: db00117
DrugCentral: histidine
Synonymous :(s)-4-(2-amino-2-carboxyethyl)imidazole | (s)-a-amino-1h-imidazole-4-propanoic acid | (s)-alpha-amino-1h-imidazole-4-propanoic acid | (s)-alpha-amino-1h-imidazole-4-propionic acid | (s)-α-amino-1h-imidazole-4-propanoic acid | his | histidina | histidine | l-(−)-histidine | l-histidin | l-histidine



Drug Sentece Context


Table 1. Analysis of context sentence of histidine gene in 5 abstracts.

pmid sentence
32553046 These parasites lack or have altered genes encoding histidine-rich proteins (HRPs) 2 and 3, the antigens recognized by HRP2-based RDTs.
32658489 The controversial and unprovable concept of aromaticity here enjoys being the agent that rationalizes the seemingly innocent role of histidine (His41 of Mpro).
32683439 A pair of histidine residues that are conserved in coronavirus spike proteins are predicted to be electrostatically frustrated at acidic pH in both pre- and post-fusion conformations. […] We suggest that an intermediate expanded conformation at endosomal pH could relax the frustration, allowing histidine protonation, and facilitating conformational conversion of coronavirus spike protein.
32765939 It is suggested that the non-toxic dipeptide carnosine (beta-alanyl-L-histidine) should be examined as a potential protective agent against COVID-19 infection and inflammatory consequences especially in the elderly.
32855259 A rare variant at bp 23463 of the SARS-CoV-2 genome was found, which corresponds to the S1 subunit of the spike protein, changing an arginine (R) residue to histidine (H).
32871846 Ivermectin docked in the region of leucine 91 of the spike and histidine 378 of the ACE2 receptor.
32919067 From analyses of spike protein sequences we identify patches of histidine and carboxylate groups that could be involved in transient proton binding.
32979815 The relative binding poses of Z93 fitted well in the binding site of both proteases and showed consensus π-π stacking and H-bond interactions with histidine and aspartate/asparagine residues of the catalytic triad.