HESPERIDIN


DrugBank ID: db04703
DrugCentral: hesperidin
Synonymous :(s)-(−)-hesperidin | cirantin | ciratin | hesperetin 7-o-rutinoside | hesperidin | hesperidina | hesperidoside



Drug Sentece Context


Table 1. Analysis of context sentence of hesperidin gene in 6 abstracts.

pmid sentence
32329408 We identified several natural molecules like δ-viniferin, myricitrin, taiwanhomoflavone A, lactucopicrin 15-oxalate, nympholide A, afzelin, biorobin, hesperidin and phyllaemblicin B that strongly binds to SARS-CoV-2 MPro.
32362245 All the studied molecules could bind to the active site of the SARS-CoV-2 protease (PDB: 6Y84), out of which rutin (a natural compound) has the highest inhibitor efficiency among the 33 molecules studied, followed by ritonavir (control drug), emetine (anti-protozoal), hesperidin (a natural compound), lopinavir (control drug) and indinavir (anti-viral drug).
32531538 Hesperidin is a classical herbal medicine used worldwide for a long time with an excellent safety profile. […] Hesperidin is a well-known herbal medication used as an antioxidant and anti-inflammatory agent. […] Available shreds of evidence support the promising use of hesperidin in prophylaxis and treatment of COVID 19. […] Herein, we discuss the possible prophylactic and treatment mechanisms of hesperidin based on previous and recent findings. […] Hesperidin can block coronavirus from entering host cells through ACE2 receptors which can prevent the infection. […] Anti-viral activity of hesperidin might constitute a treatment option for COVID-19 through improving host cellular immunity against infection and its good anti-inflammatory activity may help in controlling cytokine storm. […] Hesperidin mixture with diosmin co-administrated with heparin protect against venous thromboembolism which may prevent disease progression. […] Based on that, hesperidin might be used as a meaningful prophylactic agent and a promising adjuvant treatment option against SARS-CoV-2 infection.