HESPERETIN
DrugBank ID: db01094
DrugCentral: hesperetin
Synonymous :(−)-(s)-hesperetin | (−)-hesperetin | (s)-2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4h-1-benzopyran-4-one | 3’,5,7-trihydroxy-4’-methoxyflavanone | hesperitin
Drug Sentece Context
Table 1. Analysis of context sentence of hesperetin gene in 4 abstracts.
| pmid | sentence |
|---|---|
| 32545268 | These flavonoid-based phytomedicines include: caflanone, Equivir, hesperetin, myricetin, and Linebacker. |
| 32557405 | With the aid of in silico techniques such as molecular docking and druggability studies, we have proposed several natural active compounds including glycyrrhizin, bicylogermecrene, tryptanthrine, β-sitosterol, indirubin, indican, indigo, hesperetin, crysophanic acid, rhein, berberine and β-caryophyllene which can be encountered as potential herbal candidate exhibiting anti-viral activity against SARS-CoV-2. |
| 32735799 | Here, we reviewed the capacity of well-known (e.g. quercetin, baicalin, luteolin, hesperetin, gallocatechin gallate, epigallocatechin gallate) and uncommon (e.g. scutellarein, amentoflavone, papyriflavonol A) flavonoids, secondary metabolites widely present in plant tissues with antioxidant and anti-microbial functions, to inhibit key proteins involved in coronavirus infective cycle, such as PLpro, 3CLpro, NTPase/helicase. |
| 33292085 | Polyphenols that qualified the pharmacological parameters (indigo, sinigrin, hesperetin and daidzein) and two well-known Mpro inhibitors (N3 and lopinavir) were subjected to molecular docking studies. […] Two of them (sinigrin and hesperetin) were selected by comparing their binding affinities with N3 and lopinavir. […] Sinigrin and hesperetin interacted with the two most important catalytic residues of Mpro (His41 and Cys145). […] The Mpro-hesperetin complex was more compact and less expanded than Mpro-sinigrin complex. |
| 33452734 | Hesperetin, eriodictyol, luteolin, quercetin, and naringenin were the potentially effective active ingredients against COVID-19. |