GUANOSINE


DrugBank ID: db02857
DrugCentral: guanosine
Synonymous :2-amino-1,9-dihydro-9-β-d-ribofuranosyl-6h-purin-6-one | 2(3h)-imino-9-β-d-ribofuranosyl-9h-purin-6(1h)-one | 9-β-d-ribofuranosyl-guanine | guanine riboside | guanine-9-β-d-ribofuranoside | guanosin | guanosina | guo



Drug Sentece Context


Table 1. Analysis of context sentence of guanosine gene in 1 abstracts.

pmid sentence
32222463 In addition, the results suggest guanosine derivative (IDX-184), Setrobuvir, and YAK as top seeds for antiviral treatments with high potential to fight the SARS-CoV-2 strain specifically.
32567979 We performed homology modeling and molecular dynamic (MD) simulation, in order to understand the molecular architecture of Guanosine-P3-Adenosine-5’,5’-Triphosphate (G3A) binding with C-terminal N7-MTase domain of nsp14 from SARS-CoV-2.
32950529 This study revealed that Rifabutin, Rifapentine, Fidaxomicin, 7-methyl-guanosine-5’-triphosphate-5’-guanosine and Ivermectin have a potential inhibitory interaction with RdRp of SARS-CoV-2 and could be effective drugs for COVID-19.
32978971 Like many viruses, SARS-CoV-2 has evolved strategies to circumvent innate immune detection, including low cytosine-phosphate-guanosine (CpG) levels in the genome, glycosylation to shield essential elements including the receptor-binding domain, RNA shielding and generation of viral proteins that actively impede anti-viral interferon responses.