GLECAPREVIR
DrugBank ID: db13879
DrugCentral: glecaprevir
Synonymous :glécaprévir | glecaprevir | glecaprevirum
Drug Sentece Context
Table 1. Analysis of context sentence of glecaprevir gene in 2 abstracts.
| pmid | sentence |
|---|---|
| 32441299 | Using well-defined computational methods, we identified Glecaprevir and Maraviroc as the best inhibitors CoV-2 Mpro. […] Glecaprevir and Maraviroc bind to the conserved substrate-binding pocket of SARS-CoV-2 Mpro. […] This work provides sufficient evidence for the use of Glecaprevir and Maraviroc for the therapeutic management of COVID-19. |
| 32748740 | The results suggest the effectiveness of Beclabuvir, Nilotinib, Tirilazad, Trametinib and Glecaprevir as potent drugs against SARS-CoV-2 since they tightly bind to its main protease. |
| 32837113 | A few promising leads with dual inhibition potential were identified among FDA approved antiviral drugs which include DB13879 (Glecaprevir), DB09102 (Daclatasvir), molecule DB09297 (Paritaprevir) and DB01072 (Atazanavir). |
| 32837954 | According to the results, glecaprevir, paritaprevir, simeprevir, ledipasvir, glycyrrhizic acid, TMC-310911, and hesperidin showed highly favorably free binding energies with all tested target proteins. |
| 33168456 | Similarly Indinavir showed the highest binding energy of -11.5 kcal/mol against the target protein RdRp and Dolutegravir, Elbasvir, Tipranavir, Taltegravir, Grazoprevir, Daclatasvir, Glecaprevir, Ledipasvir, Pibrentasvir and Velpatasvir showed a binding energy value in range from -8 to -11.2 kcal/mol. |