GANCICLOVIR


DrugBank ID: db01004
DrugCentral: ganciclovir
Synonymous :2-(6-amino-purin-9-ylmethoxy)-propane-1,3-diol | 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-1h-purin-6(9h)-one | 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-3h-purin-6(9h)-one | 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-9h-purin-6-ol | 2-amino-9-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1,9-dihydro-purin-6-one | 2-amino-9-(2-hydroxy-1-hydroxymethylethoxymethyl)-6,9-dihydro-1h-6-purinone | 9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine | 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine | ga2 | ganciclovir | ganciclovirum | gancyclovir



Drug Sentece Context


Table 1. Analysis of context sentence of ganciclovir gene in 4 abstracts.

pmid sentence
32023685 Antiviral drugs commonly used in clinical practice, including neuraminidase inhibitors (oseltamivir, paramivir, zanamivir, etc.), ganciclovir, acyclovir and ribavirin, are invalid for 2019-nCoV and not recommended.
32488835 Through this paper, we provided the list of possible chemical ligands (Meglumine, Vidarabine, Adenosine, D-Sorbitol, D-Mannitol, Sodium_gluconate, Ganciclovir and Chlorobutanol) and peptide drugs (combination of isoleucine, lysine and proline) from the databases to guide the experimental scientists and validate the molecules which can combat the virus in a shorter time.
32562705 While all 11 molecules tested displayed incorporation, 6 exhibited immediate termination of the polymerase reaction (triphosphates of Carbovir, Ganciclovir, Stavudine and Entecavir; 3’-OMe-UTP and Biotin-16-dUTP), 2 showed delayed termination (Cidofovir diphosphate and 2’-OMe-UTP), and 3 did not terminate the polymerase reaction (2’-F-dUTP, 2’-NH2-dUTP and Desthiobiotin-16-UTP). […] Prodrugs of five of these nucleotide analogues (Cidofovir, Abacavir, Valganciclovir/Ganciclovir, Stavudine and Entecavir) are FDA-approved medications for treatment of other viral infections, and their safety profiles are well established.