FLUOXETINE


DrugBank ID: db00472
DrugCentral: fluoxetine
Synonymous :(+-)-n-methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine | (+-)-n-methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine | fluoxetin | fluoxetina | fluoxetine | fluoxétine | fluoxetinum



Drug Sentece Context


Table 1. Analysis of context sentence of fluoxetine gene in 3 abstracts.

pmid sentence
32522674 Some of these drugs -particularly azithromycin and other macrolides, indomethacin and some other non-steroidal anti-inflammatory drugs, proton pump inhibitors and fluoxetine - could provide additional therapeutic benefits in addition to the potential antiviral effect that is still to be confirmed by well-controlled clinical trials.
32975484 We find that fluoxetine, a widely used antidepressant and a functional inhibitor of acid sphingomyelinase (FIASMA), efficiently inhibited the entry and propagation of SARS-CoV-2 in the cell culture model without cytotoxic effects and also exerted potent antiviral activity against two currently circulating influenza A virus subtypes, an effect which was also observed upon treatment with the FIASMAs amiodarone and imipramine. […] Mechanistically, fluoxetine induced both impaired endolysosomal acidification and the accumulation of cholesterol within the endosomes.