FAMOTIDINE


DrugBank ID: db00927
DrugCentral: famotidine
Synonymous :(1-amino-3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)propylidene)sulfamide | 3-(((2-((aminoiminomethyl)amino)-4-thiazolyl)methyl)thio)-n-(aminosulfonyl)propanimidamide | 3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)-n(sup 2)-sulfamoylpropionamidine | famotidina | famotidine | famotidinum | n-sulfamoyl-3-((2-guanidinothiazol-4-yl)methylthio)propionamide



Drug Sentece Context


Table 1. Analysis of context sentence of famotidine gene in 11 abstracts.

pmid sentence
32374264 This paper briefly summarizes why cimetidine or famotidine, dipyridamole, fenofibrate or bezafibrate, and sildenafil citrate are worth considering for patients with COVID-19. […] Clinical trials to assess efficacy are already underway for famotidine, dipyridamole, and sildenafil, and further trials of all these agents will be important in due course.
32499303 The over-the-counter histamine-2 receptor antagonist famotidine is a putative therapy for COVID-19. […] We quantitively assessed longitudinal changes in patient reported outcome measures in non-hospitalised patients with COVID-19 who self-administered high-dose famotidine orally. […] Data on demographics, COVID-19 diagnosis, famotidine use, drug-related side effects, temperature measurements, oxygen saturations and symptom scores were obtained using questionnaires and telephone interviews. […] Ten consecutive patients with COVID-19 who self-administered high-dose oral famotidine were identified. […] The most frequently used famotidine regimen was 80 mg three times daily (n=6) for a median of 11 days (range: 5-21 days). […] Famotidine was well tolerated. […] All patients reported marked improvements of disease related symptoms after starting famotidine. […] The combined symptom score improved significantly within 24 hours of starting famotidine and peripheral oxygen saturation (n=2) and device recorded activity (n=1) increased. […] The results of this case series suggest that high-dose oral famotidine is well tolerated and associated with improved patient-reported outcomes in non-hospitalised patients with COVID-19.