EPINEPHRINE


DrugBank ID: db00668
DrugCentral: epinephrine
Synonymous :(−)-(r)-epinephrine | (−)-3,4-dihydroxy-α-((methylamino)methyl)benzyl alcohol | (−)-adrenaline | (r)-(-)-adnephrine | (r)-(-)-adrenaline | (r)-(-)-epinephrine | (r)-(-)-epirenamine | (r)-(−)-adrenaline | 4-[(1r)-1-hydroxy-2-(methylamino)ethyl]-1,2-benzenediol | adrénaline | adrenaline | epinefrin | epinefrina | epinephrin | epinephrine | epinephrinum | l-adrenaline | levoepinephrine



Drug Sentece Context


Table 1. Analysis of context sentence of epinephrine gene in 5 abstracts.

pmid sentence
32356252 These two medications may precipitate ventricular dysrhythmias, necessitating cardiac and electrolyte monitoring, and in severe cases, treatment with epinephrine and high-doses of diazepam.
32417446 Assuming similar SRIT rates, HITSA was found to be a cost-effective option with an incremental cost-effectiveness ratio of $44,554/quality-adjusted life-year when considering both incremental epinephrine autoinjector costs and coronavirus disease 2019 risks. […] Excluding epinephrine autoinjector costs, HISTA dominated other options. […] However, outside of pandemic considerations, HITSA was not cost-effective (incremental cost-effectiveness ratio, $198,877,286) at annual epinephrine autoinjector costs above $287.
32457932 Infusions of epinephrine titrated to treat unstable hypotension, as well as potassium for severe hypokalemia may be required.
32488505 All children but one needed an inotropic/vasoactive drug support (epinephrine, n = 12; milrinone, n = 10; dobutamine, n = 6, norepinephrine, n = 4) and 8 were intubated.
32886428 She was successfully treated with deep sedation and low dosage of epinephrine.
32961304 EMS caseload decreased during the pandemic period, however, delays to key interventions (time-to-first defibrillation, time-to-first epinephrine) significantly increased.
32962495 COVID-19 is less severe and rarely fatal in children than in adults, which could be caused by greater fluctuations of plasma epinephrine in children. […] Application of epinephrine pulses with a specific amplitude may be considered an intervention to minimize the severity of COVID-19.
32980228 Each received multiple (≥3) doses of nebulized racemic epinephrine with minimal to no improvement shortly after medication.
33091034 No difference regarding resuscitation duration, epinephrine and amiodarone administration, and mechanical compression device use were highlighted.
33220705 The vasoconstrictive effect of adrenaline (epinephrine) creates a ‘bloodless’ operating field and a tourniquet is not required.
33353811 Treatment for HCQ poisoning includes sodium bicarbonate, epinephrine, and aggressive electrolyte repletion. […] He was treated with an epinephrine infusion, hypertonic sodium chloride, high-dose diazepam, sodium bicarbonate, and aggressive potassium repletion.
33354251 Three patients had grade 3 reactions and six patients used epinephrine at home.
33372818 She remained hypotensive, despite high-dose epinephrine and norepinephrine infusions as well as stress-dose hydrocortisone.
33417336 The closure times were short in the 20% and 40% of samples of collagen and ADP and collagen and epinephrine, respectively.
33444297 In addition to screening for contraindications and precautions before administering COVID-19 vaccines, vaccine locations should have the necessary supplies available to manage anaphylaxis, should implement postvaccination observation periods, and should immediately treat persons experiencing anaphylaxis signs and symptoms with intramuscular injection of epinephrine (4,5).
33447159 Other notable changes made to the chapter include the following: 1) retitled: “Anaphylaxis and other acute reactions following vaccination”; 2) inclusion of new tables: “Key distinguishing features of anaphylaxis and vasovagal syncope” and “Signs and symptoms of anaphylaxis”; and 3) updated tables: “Anaphylaxis management kit: recommended items” and “Dosage of intramuscular EPINEPHrine 1:1000 (1 mg/mL) solution, by age or weight”. […] The updated intramuscular epinephrine dosage table will aid in optimal epinephrine administration, while the revised guidance against the use of diphenhydramine hydrochloride will prevent its unnecessary stockpiling in preparation for potential mass vaccination clinics related to the coronavirus disease 2019 pandemic.