ELVITEGRAVIR


DrugBank ID: db09101
DrugCentral: elvitegravir
Synonymous :6-(3-chloro-2-fluorobenzyl)-1-[(2s)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | elvitegravir | elvitégravir | evg | gs 9137



Drug Sentece Context


Table 1. Analysis of context sentence of elvitegravir gene in 1 abstracts.

pmid sentence
32793181 Out of 113 quinoline-drugs, elvitegravir and oxolinic acid are able to interact with the NTP entry-channel and thus interfere with the RNA-directed 5’-3’ polymerase activity of SARS-CoV-2 RdRp. […] In conclusion, owing to their ability to target functional macromolecules of SARS-CoV-2, along with positive ADMET properties, quinoline,1,2,3,4-tetrahydro-1-[(2-phenylcyclopropyl)sulfonyl]-trans-(8CI), saquinavir, elvitegravir, oxolinic acid, and rilapladib are suggested for the treatment of COVID-19.