DOXYCYCLINE


DrugBank ID: db00254
DrugCentral: doxycycline
Synonymous :5-hydroxy-α-6-deoxytetracycline | 6-alpha-deoxy-5-oxytetracycline | 6alpha-deoxy-5-oxytetracycline | 6α-deoxy-5-oxytetracycline | anhydrous doxycycline | doxiciclina | doxycyclin | doxycycline | doxycycline (anhydrous) | doxycycline anhydrous | doxycyclinum



Drug Sentece Context


Table 1. Analysis of context sentence of doxycycline gene in 3 abstracts.

pmid sentence
32229706 Other anti-aging drugs should also be considered, such as Rapamycin and Doxycycline, as they behave as inhibitors of protein synthesis, blocking both SASP and viral replication. […] As Azithromycin and Doxycycline are both commonly used antibiotics that inhibit viral replication and IL-6 production, we may want to consider this general class of antibiotics that functionally inhibits cellular protein synthesis as a side-effect, for the treatment and prevention of COVID-19 disease.
32267566 Tetracyclines (e.g. tetracycline, doxycycline, and minocycline) are highly lipophilic antibiotics that are known to chelate zinc compounds on matrix metalloproteinases (MMPs)1 .
32458149 A number of anti-viral drugs such as ribavirin, remdesivir, lopinavir/ritonavir, antibiotics such as azithromycin and doxycycline, and anti-parasite such as ivermectin have been recommended for COVID-19 treatment.
32495913 A nasal swab for COVID-19 was performed, which resulted positive, and so therapy with doxycycline, hydroxychloroquine and antiviral agents was started.
32566483 In this article, we argue for the potential benefits of using doxycycline with either hydroxycholoroquine or other putative agents for COVID-19 treatment, as doxycycline has antiviral and anti-inflammatory activities by dampening the cytokine storm and to prevent lung damage.