DIPHENHYDRAMINE
DrugBank ID: db01075
DrugCentral: diphenhydramine
Synonymous :2-(benzhydryloxy)-n,n-dimethylethylamine | 2-diphenylmethoxy-n,n-demthylethanamine | difenhidramina | diphenhydramine | diphenhydraminum | n-(2-(diphenylmethoxy)ethyl)-n,n-dimethylamine | o-benzhydryldimethylaminoethanol | α-(2-dimethylaminoethoxy)diphenylmethane | β-dimethylaminoethanol diphenylmethyl ether | β-dimethylaminoethyl benzhydryl ether
Drug Sentece Context
Table 1. Analysis of context sentence of diphenhydramine gene in 3 abstracts.
| pmid | sentence |
|---|---|
| 33309272 | Usage of diphenhydramine, hydroxyzine and azelastine was associated with reduced incidence of SARS-CoV-2 positivity in subjects greater than age 61. […] We found diphenhydramine, hydroxyzine and azelastine to exhibit direct antiviral activity against SARS-CoV-2 in vitro. […] Clinical studies are needed to measure the effectiveness of diphenhydramine, hydroxyzine and azelastine for disease prevention, for early intervention, or as adjuvant therapy for severe COVID-19. |
| 33447159 | The use of diphenhydramine hydrochloride as adjunctive treatment in the management of anaphylaxis in a community setting is no longer recommended. […] The updated intramuscular epinephrine dosage table will aid in optimal epinephrine administration, while the revised guidance against the use of diphenhydramine hydrochloride will prevent its unnecessary stockpiling in preparation for potential mass vaccination clinics related to the coronavirus disease 2019 pandemic. |