DATE
DrugBank ID: db10632
DrugCentral: date
Synonymous : None
Drug Sentece Context
Table 1. Analysis of context sentence of date gene in 2334 abstracts.
| pmid | sentence |
|---|---|
| 31986261 | No data on person-to-person or nosocomial transmission have been published to date. |
| 31997390 | To investigate the genetic diversity, time origin, and evolutionary history of the 2019-nCoV outbreak in China and Thailand, a total of 12 genome sequences of the virus with known sampling date (24 December 2019 and 13 January 2020) and geographic location (primarily Wuhan city, Hubei Province, China, but also Bangkok, Thailand) were analyzed. |
| 32013309 | Coronavirus can cause respiratory syndrome which to date has affected about twelve thousand individuals, especially in China. |
| 32023775 | We reviewed the currently available literature to provide up-to-date guidance on control measures to be implemented by public health authorities. |
| 32031570 | Retrospective, single-center case series of the 138 consecutive hospitalized patients with confirmed NCIP at Zhongnan Hospital of Wuhan University in Wuhan, China, from January 1 to January 28, 2020; final date of follow-up was February 3, 2020. |
| 32037389 | The remaining patient with severe pneumonia had shown signs of improvement by the cutoff date for data collection. |
| 32056249 | Based on the advice of the International Health Regulations Emergency Committee and the fact that to date 24 other countries also reported cases, the WHO Director-General declared that the outbreak of 2019-nCoV constitutes a Public Health Emergency of International Concern on 30 January 2020. |
| 32079150 | Using publicly available event-date data from the ongoing epidemic, the present study investigated the incubation period and other time intervals that govern the epidemiological dynamics of COVID-19 infections. |
| 32083985 | To date, CT findings have been recommended as major evidence for clinical diagnosis of COVID-19 in Hubei, China. |
| 32087334 | To date, there are no clinically approved vaccines or antiviral drugs available for these human coronavirus infections. |
| 32105680 | Clinicians should continue to follow the Centers for Disease Control and Prevention website to stay up to date with the latest information (https://www.cdc.gov/coronavirus/2019-nCoV/hcp/index.html). |
| 32125362 | Descriptive case series of the first 18 patients diagnosed with polymerase chain reaction (PCR)-confirmed SARS-CoV-2 infection at 4 hospitals in Singapore from January 23 to February 3, 2020; final follow-up date was February 25, 2020. |
| 32141588 | To date, the outbreak has spread to most provinces in China and 25 other countries within a relatively short period. |
| 32143502 | Although the fatality rate of SARS-CoV-2 is currently lower than SARS-CoV, the virus seems to be highly contagious based on the number of infected cases to date. |
| 32145719 | To date, the controlling of outbreak of corona virus disease 2019 (COVID-19) has entered into a critical period in China. |
| 32155789 | Specific up-to-date and accurate health information (e.g., treatment, local outbreak situation) and particular precautionary measures (e.g., hand hygiene, wearing a mask) were associated with a lower psychological impact of the outbreak and lower levels of stress, anxiety, and depression (p < 0.05). Conclusions: During the initial phase of the COVID-19 outbreak in China, more than half of the respondents rated the psychological impact as moderate-to-severe, and about one-third reported moderate-to-severe anxiety. |
| 32164053 | The first patient’ symptom onset date in the Daegu/NGP outbreak was assumed as January 22, 2020. […] The R according to the start date of the effect of preventive measures was estimated. |
| 32166607 | There have been around 96,000 reported cases of coronavirus disease 2019 (COVID-2019) and 3300 reported deaths to date (05/03/2020). |
| 32167524 | The final date of follow-up was February 13, 2020. |
| 32171059 | The four datasets we fitted to were: daily number of new internationally exported cases (or lack thereof), by date of onset, as of Jan 26, 2020; daily number of new cases in Wuhan with no market exposure, by date of onset, between Dec 1, 2019, and Jan 1, 2020; daily number of new cases in China, by date of onset, between Dec 29, 2019, and Jan 23, 2020; and proportion of infected passengers on evacuation flights between Jan 29, 2020, and Feb 4, 2020. […] We used an additional two datasets for comparison with model outputs: daily number of new exported cases from Wuhan (or lack thereof) in countries with high connectivity to Wuhan (ie, top 20 most at-risk countries), by date of confirmation, as of Feb 10, 2020; and data on new confirmed cases reported in Wuhan between Jan 16, 2020, and Feb 11, 2020. |
| 32171869 | Final date of follow-up was February 25, 2020. |
| 32171872 | The primary endpoint was a negative conversion rate of coronavirus from the date of COVID-19 diagnosis(day7, day14), and assessed whether the pneumonia was progressing or improving by chest CT (day7). |
| 32173241 | To date, effective treatment is lacking; however, clinical trials investigating the efficacy of several agents, including remdesivir and chloroquine, are underway in China. |
| 32175421 | Several studies have been done to estimate the basic reproduction number in the early phase of this outbreak, yet there are no reliable estimates of case fatality rate (CFR) for COVID-19 to date. |
| 32176772 | All patients were confirmed to be infected with SARS-CoV-2 and the final date of follow-up was February 4, 2020. |
| 32178768 | Contacts were people with exposure to a patient with COVID-19 on or after the patient’s symptom onset date. |
| 32179124 | No systematic reviews on COVID-19 have been published to date. |
| 32180292 | From reports of 32 women to date affected by COVID-19 in pregnancy, delivering 30 babies (one set of twins, three ongoing pregnancies), seven (22%) were asymptomatic and two (6%) were admitted to the intensive care unit (ICU), one of whom remained on extracorporeal membrane oxygenation. […] No maternal deaths have been reported to date. […] Compared with SARS and MERS, COVID-19 appears less lethal, acknowledging the limited number of cases reported to date and that one woman remains in a critical condition. |
| 32183901 | To date, no specific antiviral treatment has proven effective; hence, infected people primarily rely on symptomatic treatment and supportive care. |
| 32186952 | However, to date, no licensed antiviral treatment or vaccine exists for MERS and SARS. |
| 32196406 | While these common sense points will always be helpful, it is important that you keep up to date with the advice being given by the Centers for Disease Control and Prevention (CDC) and NHS England and how it might affect you personally. […] These suggestions have been produced using the most up-to-date advice available to us from our Scientific and Medical Advisors and are not intended to replace or supersede advice you may have been given from your health care professional. |
| 32196426 | Expected final online publication date for the Annual Review of Virology, Volume 7 is September 29, 2020. |
| 32205090 | Evidencing eTCB effectiveness is Taiwan’s success to date in containing and controlling the community-hospital-community transmission cycle. |
| 32210236 | All data are geo-coded and, where available, include symptoms, key dates (date of onset, admission, and confirmation), and travel history. |
| 32211816 | This cohort study was conducted from January 20, 2020, to February 10, 2020, in a single center at Renmin Hospital of Wuhan University, Wuhan, China; the final date of follow-up was February 15, 2020. |
| 32212779 | To date, there is no scientific guideline regarding management of cancer patients in a background of coronavirus outbreak.<br />. |
| 32213786 | As the situation with COVID-19 rapidly unfolds, it is critical that obstetricians keep up to date. |
| 32216717 | The severity of CXR findings peaked at 10-12 days from the date of symptom onset. |
| 32217113 | To date, the outcomes of 55 pregnant women infected with COVID-19 and 46 neonates have been reported in the literature, with no definite evidence of vertical transmission. |
| 32219428 | The study was conducted at the infectious disease department, Shenzhen Third People’s Hospital in Shenzhen, China, from January 20, 2020, to March 25, 2020; final date of follow-up was March 25, 2020. |
| 32220284 | The final date of follow-up was Feb 12, 2020. |
| 32224151 | To date, the clinical characteristics of COVID-19-infected cancer patients are largely unknown. |
| 32225133 | Assuming an arithmetical growth in the second variation of the data, we present a cubic adjustment model in which we estimate over 100 000 cases at 120 days consistent with the data recorded to date. |
| 32232520 | Since our hospital received the first patient with COVID-19 in Singapore, our centre has managed 16 COVID-19 cases to date. |
| 32232652 | By the end of follow-up date (Mar. 3, 2020), there were 16 non-severe cases (64%) and 9 severe cases (36%), 5 cases were dead (20%). |
| 32233034 | To date, multiple position statements and guidelines have been issued by various professional organizations to recommend practices in endoscopic procedures. |
| 32234451 | Although related to the Severe Acute Respiratory Syndrome (SARS) and the Middle East Respiratory Syndrome (MERS), COVID-19 shows some peculiar pathogenetic, epidemiological and clinical features which have not been completely understood to date. |
| 32234466 | Coronavirus disease 2019 (COVID-19) originated in the city of Wuhan, Hubei Province, Central China, and has spread quickly to 72 countries to date. |
| 32234728 | Every month, DTB scans sources of information on treatments, disease management and other healthcare topics for key items to bring to our readers’ attention and help them keep up to date. |
| 32235085 | It spread rapidly and to date has killed 3,242 persons with more than 81,000 cases of infection in China and causing over 126,000 global cases and 5,414 deaths in 166 other countries around the world, especially Italy. |
| 32236594 | Although to date it is considered that Covid‑19 originates from bats (96.2% overall genome sequence identity) (1), the type of intermediate animals that caused the transmission to humans remains unknown (2-4). |
| 32240128 | Among 23 (30%) residents with positive test results, 10 (43%) had symptoms on the date of testing, and 13 (57%) were asymptomatic. |
| 32241244 | To date, computed tomography (CT) findings have been recommended as major evidence for the clinical diagnosis of COVID-19 in Hubei, China. |
| 32241328 | Following this date, attention quickly increased and has remained high over time. |
| 32245904 | To date, no effective treatment has been identified and management for critically ill patients relies on management in intensive care units. |
| 32247050 | Based on recently published literatures, official documents and selected up-to-date preprint studies, we reviewed the virology and origin, epidemiology, clinical manifestations, pathology and treatment of 2019-nCoV infection, in comparison with severe acute respiratory syndrome coronavirus (SARS-CoV) and middle east respiratory syndrome coronavirus (MERS-CoV) infection. |
| 32247326 | We used the date of the fourth revision of the case definition (Jan 27) to divide the epidemic into two time periods (Dec 24 to Jan 27, and Jan 28 to Feb 17) as the date of symptom onset. |
| 32250385 | Date of final follow-up was March 25, 2020. |
| 32250958 | The aim of this paper is to describe the utilization of a dedicated mobile health (mHealth) platform to disseminate up-to-date and validated information about SARS-CoV-2 to all medical staff of the Children’s Hospital at the University Hospitals of Geneva. |
| 32251794 | To date, no specific treatment has been proven to be effective for SARS-CoV-2 infection. |
| 32251848 | This article delineates some of those challenges and the responses to them which are known, to date. |
| 32252141 | The purpose of this review is to summarize known-to-date information about SARS-CoV-2, transmission of SARS-CoV-2, and clinical features. |
| 32254064 | To date, there are no proven options for prophylaxis for those who have been exposed to SARS-CoV-2, nor therapy for those who develop COVID-19. |
| 32255382 | Demographic, clinical, laboratory, and treatment data were collected and analyzed, and final date of follow-up was February 24, 2020. |
| 32258351 | It is imperative for public health practitioners and the One Health community to stay up to date on the most promising potential therapeutic options that are under investigation. […] Thus, the purpose of this review is to synthesize the knowledge to date about remdesivir as a therapeutic option for coronaviruses, with a special focus on information relevant to the One Health community. |
| 32259155 | The aim of this paper is to review all the up to date evidence, including experiences from China and Italy, to guide the safe management of such patients when undergoing gynaecological procedures. |
| 32259279 | Unpublished reports, unspecified date and location of the study or suspicion of duplicate reporting, cases with suspected COVID-19 that were not confirmed by a laboratory test, and unreported maternal or perinatal outcomes were excluded. |
| 32264957 | To date, we have found it is one of the greatest challenges to human beings in fighting against COVID-19 in the history, because SARS-CoV-2 is different from SARS-CoV and MERS-CoV in terms of biological features and transmissibility, and also found the containment strategies including the non-pharmaceutical public health measures implemented in China are effective and successful. |
| 32265182 | To date, there are no medical treatments for COVID-19 with proven effectiveness. |
| 32267098 | In this review article, we summarized the published literatures to date concerning four different aspects: (a) gastrointestinal manifestations of COVID-19 infection; (b) microbiologic and virological investigations; (c) the role of fecal-oral transmission; and (d) prevention/control infection in the digestive endoscopy room. |
| 32269177 | To date, only three centers have performed a catheterization on a confirmed COVID-19 positive patient. |
| 32270371 | To date, there is no specific therapy for COVID-19. |
| 32270521 | This research statistically analyzed the effect of sex, region, infection reasons, birth year, and released or diseased date on the reported numbers of recovered and deceased cases. |
| 32271458 | The proposed classifier used different seven variables, namely, country, infection reason, sex, group, confirmation date, birth year, and region. |
| 32271722 | In the four clusters for which the date of exposure could be determined, presymptomatic transmission occurred 1-3 days before symptom onset in the presymptomatic source patient. |
| 32281052 | However, no standard treatment for this disease has been discovered to date. |
| 32281213 | Although pre-clinical results are promising, till date, there is dearth of evidence to support the efficacy of CQ or HCQ in preventing COVID-19. |
| 32281330 | Documents were screened following the inclusion criteria, and data were extracted in regard to registration date, study objective, type of design, sponsor, patient, sample size, intervention, and evaluation index. |
| 32282022 | No therapies have been shown effective to date. |
| 32283052 | To date, considerable knowledge gaps remain regarding the chest CT imaging features of COVID-19. […] We performed a systematic review and meta-analysis of results from published studies to date to provide a summary of evidence on detection of COVID-19 by chest CT and the expected CT imaging manifestations. |
| 32283108 | To date, the most promising broad-spectrum class of viral RdRp inhibitors are nucleoside analogues (NAs), with over 25 approved for the treatment of several medically important viral diseases. |
| 32283185 | To ensure availability of donor cells on the scheduled date of infusion, many sites now collect cryopreserve grafts before the start of pretransplant conditioning. |
| 32285338 | Few studies have been performed on viral transmission during surgery, but to date there is no study that demonstrates or can suggest the ability for a virus to be transmitted during surgical treatment whether open or laparoscopic. |
| 32286607 | To date, SARS-CoV-2 is known to enter the host cells via the angiotensin-converting enzyme 2 protein. |
| 32288415 | Furthermore, we propose the BAT model, which is composed of three parts: simulation of the return rush (Back), analytic hierarchy process (AHP) method, and technique for order preference by similarity to an ideal solution (TOPSIS) method, to figure out the best return date for university students. |
| 32288418 | We also evaluate the effectiveness of the quarantine measures and schedule the date to reopen Hubei Province. |
| 32289472 | To date, COVID-19 has affected over 944,181 people worldwide, resulting in over 47,312 reported deaths. […] As new findings emerge, there is an urgent need for up-to-date management guidelines. |
| 32291505 | To date there is no specific treatment available-the main goal of supportive therapy is to ascertain adequate oxygenation. |
| 32291526 | Several hypotheses have been proposed to date regarding the net effect of ACEI/ARB on COVID-19 infections. |
| 32292517 | No patient has died in our hospital to date. |
| 32292529 | As the epicentre of the initial outbreak, China has been updating the National COVID-19 Diagnostic and Treatment Guideline with up-to-date information about the disease. […] Medical professionals should diagnose and treat patients according to up-to-date guidelines. |
| 32292686 | To date, there is no specific therapy for COVID-19. |
| 32292697 | The Coronavirus disease 2019 (COVID-19) reminds us of the SARS outbreak in 2003, and up to date, corticosteroid is commonly administrated to severe patients with COVID-19. |
| 32292826 | While there is no intervention for the prevention or treatment of COVID-19 with proven clinical efficacy to date, tools to distil the current research landscape by intervention, level of evidence and those studies likely powered to address future research questions is essential. |
| 32292911 | Its accuracy has been 1.29% for the last day added and predicted by the 57 previous WHO situation reports (the date 18 March 2020). |
| 32293020 | Based on the evidence to date, there are several treatment options to consider for the relief of fever (acetaminophen, NSAID, oral glucocorticoids), cough (morphine), breathlessness (morphine, oxygen, fan), anxiety (benzodiazepines) and pain (NSAID, morphine). |
| 32293875 | Since the emergence of a novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was firstly reported from Wuhan, China, to date, neither a specific vaccine nor antiviral drug against SARS-CoV-2 is available. |
| 32294617 | Individuals should get the most up to date information from the CDC website.]. |
| 32294718 | To date, no case series have been published in Brazil. |
| 32295300 | To date, protease inhibitor drugs, especially HIV-1 protease inhibitors, have been available for human clinical use in the treatment of coronaviruses. |
| 32295811 | Every month, DTB scans sources of information on treatments, disease management and other healthcare topics for key items to bring to our readers’ attention and help them keep up to date. |
| 32298035 | This document consolidates best available evidence to date and presents recommendations to minimize the risks of aerosolization and SARS-CoV-2 exposures in both the inpatient and outpatient settings. |
| 32298149 | The purpose of this article is to critically review some of the most frequently cited studies on the use of CT for detecting COVID-19. CONCLUSION. To date, the radiology literature on COVID-19 has consisted of limited retrospective studies that do not substantiate the use of CT as a diagnostic test for COVID-19. |
| 32298480 | FDA/EMA-approved monitoring guidelines, clinical practice guidelines, and relevant, up-to-date publications regarding initiation and monitoring of beta-blocker therapy were used to inform the recommendations. |
| 32298767 | But no studies to date have systematically described liver test abnormalities in patients with COVID-19. |
| 32298982 | and Aims: No valid treatment or preventative strategy has evolved till date to counter the SARS CoV 2 (Novel Coronavirus) epidemic that originated in China in late 2019 and have since wrought havoc on millions across the world with illness, socioeconomic recession and death. |
| 32301746 | Objectives The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to date, the epidemic has gradually spread to 209 countries worldwide with more than 1.5 million infected people and 100,000 deaths. |
| 32302927 | In radiology, much of the literature to date has focused on chest CT manifestations of COVID-19 (Zhou et al. |
| 32302935 | The COVID-19 pandemic is a major health crisis affecting several nations, with over 720,000 cases and 33,000 confirmed deaths reported to date. |
| 32302954 | The final date of follow-up was February 23, 2020. |
| 32305269 | The country might not be screening optimally, considering the number of COVID-19 tests conducted to date and the suspected cases who missed testing. |
| 32305459 | The most comprehensively tested case reported to date confirmed that the vertical transmission of COVID is unlikely, but still, more evidence is needed. |
| 32307014 | To date, there have been more than 1,260,000 COVID-19 patients, with a mortality rate of approximately 5.44%. |
| 32308494 | Most studies to date on COVID-19 have focused on disease etiology and the genomics of 2019-nCoV, with few reports on the epidemiologic and clinical characteristics of infected patients. |
| 32310028 | In this narrative review we discuss current evidence around detection of SARS-CoV-2 in human tears and forms of transmissions reported to date. |
| 32310815 | To date, we have enrolled 159 participants. |
| 32312018 | To our knowledge, there has been no prospective multicentre imaging study of COVID-19 to date.We proposed a hypothesis: There are some specific CT features on Chest CT of COVID-19 patients. |
| 32312158 | The widespread impact and chronicity of this pandemic makes it unique from any crisis faced by our training programs to date. |
| 32313463 | All cases reported to date have shown radiographic evidence of pneumonia. 2019-nCoV is diagnosed by real-time reverse transcriptase polymerase chain reaction. |
| 32313660 | To date, the anti-malaria drug hydroxychloroquine found to be a treatment option for SARS-CoV-2. |
| 32313807 | To date, only one case of GBS associated with this infection has been described. |
| 32313824 | No Food and Drug Administration approved treatment is available till date. |
| 32313879 | We estimate that Feb. 11, 2020 was the date with the highest transmission risk in Wuhan, which is consistent with the actual peak period of the reported case number (Feb. |
| 32314868 | Coronavirus disease 2019 (COVID-19), the worst pandemic in more than a century, has claimed >125,000 lives worldwide to date. |
| 32315451 | We did not apply any date limit or language limits. |
| 32315963 | Till to date, no epidemiological data on mental health problems due to outbreak of the COVID-19 and mass isolation were not available. |
| 32317050 | We analysed the sources, publication date, type and topic of the retrieved articles/studies.ResultsWe included 249 articles in this scoping review. |
| 32317225 | While clinical reports from China to date demonstrate that the majority of cases remain relatively mild and recover with supportive care, it is also crucial to be well prepared for severe cases warranting intensive care. |
| 32320003 | Among the 3066 patients who remained hospitalized at the final study follow-up date (median age, 65 years [IQR, 54-75]), the median follow-up at time of censoring was 4.5 days (IQR, 2.4-8.1). |
| 32320509 | The 10th of April saw the highest number of UK daily deaths (980) to date. |
| 32321075 | In 2020, hospitalizations for SARI, compiled from the date of the first confirmed case of COVID-19 up to the 12th week, exceeded the numbers observed during the same period in each of the previous 10 years. |
| 32321524 | To date, several drugs targeting RdRp enzymes are being employed for SARS-CoV-2 infection treatment. |
| 32322159 | While NIOSH has standardized N95 and N98 at 300nm, to-date there is no filter standards, nor special filter technologies, tailored for capturing airborne viruses and 100nm nano-aerosols. |
| 32322398 | The limited clinical data about the virus’s behavior to date, especially extrapulmonary symptoms, suggest that we should be aware of the possibility of initial cerebrovascular manifestations of COVID-19. |
| 32322478 | No published treatment to date has been shown to adequately control the inflammation and respiratory symptoms associated with COVID-19, apart from oxygen therapy and assisted ventilation. |
| 32322654 | To date, the world perhaps has never waited for the summer so impatiently in the entire Anthropocene, owing to the debate whether increasing temperature and humidity will decrease the environmental endurance of SARS-CoV-2. |
| 32324358 | As several healthcare interventions are essential even during pandemics, it is necessary for professionals working in such fields to get up-to-date information about the virus and its aspects that can influence patient care and suggested actions. |
| 32327383 | Ultrasound is highly sensitive in the detection of multiple lung pathologies which can be demonstrated in conjunction with COVID-19 however to date there are no specific, nor pathognomonic findings which relate to COVID-19 on ultrasound. |
| 32328363 | To date, data on the behavioral distress and psychiatric morbidity of those suspected or diagnosed with the 2019-nCoV and their treating health professionals are lacking. |
| 32328367 | Furthermore, our review focuses on the most up-to-date clinical information for the effective management, prevention, and counseling of patients worldwide. |
| 32329432 | Reverse transcriptase-polymerase chain reaction testing, our primary diagnostic tool to date, has sensitivity and timing concerns, owing to sampling/handling errors, as well as a complex virus-host interaction. |
| 32329522 | To date, the statistics of COVID-19 reported cases show that more than 80% of infected are mild cases of disease, around 14% of infected have severe complications, and about 5% are categorized as critical disease victims. |
| 32333185 | To date, biomedical forms of curative and preventative treatments for COVID-19 are at best limited. |
| 32334502 | To date, no definitive treatment orvaccine application exists for COVID-19. |
| 32335244 | COVID 19 been declared recently as a pandemic, to date has affected over 1,8881,365 with over 119,403 deaths in accordance to the global pandemic Real-Time Report. |
| 32336927 | In the last two decades, this is the 3rd deadliest Coronavirus pandemic, following SARS which lasted between 2002 and 2003 and Middle East Respiratory Syndrome (MERS) from 2012 till date. |
| 32337148 | She was successfully treated with coronary revascularization and stent placement, and remains on the ventilator to date as she quickly developed acute respiratory distress syndrome. |
| 32337862 | This article details the correct procedure required for effective hand hygiene and emphasises the need for nurses to keep up to date with evidence-based guidelines. |
| 32339723 | Afterward, instant fatality rate was calculated according to the number of deaths and cured cases on the same estimated diagnosis date. |
| 32340050 | To date, to our knowledge there are no studies regarding attitudes and experiences of outpatient medical personnel during a pandemic. |
| 32341103 | While relevant preclinical, experimental models to date favor a protective effect of RAAS-SCoV-axis inhibition on both lung injury and survival, clinical data related to the role of RAAS modulation in the setting of SARS-CoV-2 remains limited. |
| 32341718 | In the non-Hubei region of China it is expected that the epidemic will cease on the 30th of March 2020 and following this date no new confirmed patient will be expected. |
| 32341913 | This article addresses all information collected to date on the virus, in accordance with the guidelines of international health care institutions, and provides a comprehensive protocol for managing possible exposure to patients or those suspected of having coronavirus. |
| 32342026 | Articles listed in PubMed and Google sources for up-to-date information. |
| 32342849 | This is to our knowledge the longest duration of viral shedding reported to date. |
| 32343428 | All contacts of three clusters have been isolated and no new confirmed cases have been identified to date. |
| 32344456 | The goal of this review is to provide up-to-date, evidence-based recommendations or expert opinion when evidence is limited, for performing regional anaesthesia procedures in patients with suspected or confirmed COVID-19 infection. |
| 32344679 | To date, there are no available vaccines or specific therapeutic drugs to treat the virus. |
| 32345226 | To date, the clinical characteristics of COVID-19 patients in the non-Wuhan areas of Hubei Province in China have not been described. |
| 32346490 | To date, no licensed antiviral drugs or vaccines are available against COVID-19 although several clinical trials are underway to test possible therapies. |
| 32347685 | The first part focused on the epidemiology until that date. |
| 32347743 | No arrhythmogenic deaths were reported. Conclusions - In the largest reported cohort of COVID-19 patients to date treated with chloroquine/hydroxychloroquine {plus minus} azithromycin, no instances of TdP or arrhythmogenic death were reported. |
| 32348045 | To date, there is no evidence to support an increase in complications of COVID-19 in these patients. |
| 32348588 | To date, there is no evidence of any effective treatment for COVID-19. |
| 32348591 | This document provides clinical practice guidelines based on available evidence to date to balance the risks of SARS-CoV-2 exposure with the risks associated with dysphagia. |
| 32348598 | Patients should exercise social distancing, optimise co-morbidities and be up to date with influenza and pneumococcal vaccines. |
| 32348627 | From November 2019 to date, almost six thousand papers have been published on COVID-19, the disease caused by SARS-CoV-2 infection. |
| 32350048 | To date, there is limited comparison data for these different testing platforms. |
| 32351037 | The onset date of the first case in Shanghai was 28 December, with the peak appearing on 27 January. |
| 32351056 | The date of population expansion was calculated based on the expansion parameter tau ( τ) using the formula t= τ/2 u. |
| 32351243 | Multiple gastroenterology associations have issued guidance and statements that would help healthcare providers in navigating these unprecedented and difficult times, and the Saudi Gastroenterology Association has provided this statement in an effort to bring the most up to date information for the management of endoscopy units in terms of resources, manpower planning, scheduling, as well as infection control policies and leadership. |
| 32353457 | Most studies on previous respiratory virus epidemics to date suggest surgical masks are not inferior compared with N95 respirators in terms of protective efficacy among healthcare workers. |
| 32353723 | Three megacities were differentiated by the spatial patterns and quantities of infected communities, average cases per community, the percentages of imported cases, as well as the potential risks, although their COVID-19 infection situations have been preliminarily contained to date. |
| 32356654 | The impact of dietary patterns and the commensal microbiome on susceptibility to and severity of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has been largely ignored to date. |
| 32356867 | The final follow-up date was April 2, 2020. |
| 32356910 | This review was conducted to evaluate the effectiveness of CPT therapy in COVID-19 patients based on the publications reported till date. |
| 32357381 | This article aims to provide an overview of the various methods and their evidence till date. |
| 32358406 | To date, 1 patient was discharged from hospital, while the other had been transferred to the rehabilitation department. |
| 32359226 | The results demonstrated that to date, neonatal COVID-19 infection is uncommon, generally acquired postnatally, and associated with favorable respiratory outcomes. |
| 32359227 | To date, no information on late-onset infection in newborns to mother with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contracted in pregnancy are available. |
| 32359819 | Herein, we briefly describe the affects of COVID-19 on Interventional Radiology residency training and summarize up to date guidance by governing bodies and key stakeholders. |
| 32360053 | Patient information was collected and organized by date of visit, sex, age, and systemic disease history. |
| 32360108 | All data were reported at death or after a minimum of 14 days from date of admission with COVID-19 disease. |
| 32360480 | Further, chloroquine and hydroxychloroquine, and off-label antiviral drugs, such as the nucleotide analogue remdesivir, HIV protease inhibitors lopinavir and ritonavir, broad-spectrum antiviral drugs arbidol and favipiravir as well as antiviral phytochemicals available to date may limit spread of SARS-CoV-2 and morbidity and mortality of COVID-19 pandemic. |
| 32361446 | Data started from 12 February 2020-09 April 2020 (the date on Covid-19 was detected in Spain). |
| 32362424 | In the largest number of cases described to date of hospitalized patients with SARS-CoV-2 disease (2019-nCoViD), 26% required care in an intensive care unit (ICU). […] This narrative literature review aims to gather the main contributions in the area of intensive care to date in relation to the epidemiology, clinic, diagnosis and management of 2019-nCoViD. |
| 32365233 | To date the group, comprising UK-based specialists in diabetes, pharmacy and psychology, have produced two sets of guidelines which will be continually revised as new evidence emerges. |
| 32367558 | To date, there are no data in the literature on the comorbid dermatologic diseases and COVID-19. |
| 32367683 | From November 1, 2019 to March 31, 2020, we compared outcome of patients admitted for acute ST-elevation MI (STEMI) and non-ST elevation MI (NSTEMI) before (group 1) and after (group 2) January 25, 2020 which was the date when Hong Kong hospitals launched emergency response measures to combat COVID-19. |
| 32370766 | To date, there is no specific anti-COVID-19 treatment. |
| 32370984 | The goal of the present article is to provide up-to-date information on potential mental health risks associated with exposure of health professionals to the COVID-19 pandemic. […] Stress may also be caused by organizational factors, such as depletion of personal protection equipment, concerns about not being able to provide competent care if deployed to new area, concerns about rapidly changing information, lack of access to up-to-date information and communication, lack of specific drugs, the shortage of ventilators and intensive care unit beds necessary to care for the surge of critically ill patients, and significant change in their daily social and family life. |
| 32370986 | Moreover, to date there is no evidence that ACEi or ARB administration facilitates SARS-COV2 cell entry by increasing ACE2 tissue expression in either animal or human studies. |
| 32371558 | To date there is no evidence from randomized controlled trials that any single therapy improves outcomes in patients infected with COVID-19. |
| 32372877 | To-date, unfortunately there are no test standards for nano-aerosols (≤100 nm). |
| 32374903 | The major mutation detected to date in the SARS-CoV-2 viral envelope spike protein, which is responsible for virus attachment to the host and is also the main target for host antibodies, is a mutation of an aspartate (D) at position 614 found frequently in Chinese strains to a glycine (G). |
| 32375067 | Under moderate control of scenario two, the number of infected people will increase by 1.43-1.55 times of that in scenario one, the date of the epidemic being controlled will be delayed by about 10 days, and Algeria, Nigeria, and Kenya are in accordance with this situation. |
| 32375144 | There is, to date, minimal, unconfirmed evidence of spontaneous vertical transmission, though it may theoretically be increased with some procedures. |
| 32375488 | The severe acute respiratory syndrome coronavirus 2 pandemic is to date affecting more than a million of patients and is challenging healthcare professionals around the world. |
| 32375909 | According to the contents of the reports, we recorded in detail the gender, age, first symptom date, death date, primary symptoms, chronic fundamental diseases, and other data of the patients, and carried out analyses and discussion. |
| 32376350 | Assuming a service restoration date of either June 1 or July 1, we calculated the need to perform 216% or 263% of monthly baseline volume, respectively, to clear the backlog in one month. |
| 32377486 | To date, the number of confirmed cases and deaths has risen exponentially in more than 200 countries, with an estimated crude mortality ratio of at least over 2%. |
| 32377576 | Chatbots, if effectively designed and deployed, could help us by sharing up-to-date information quickly, encouraging desired health impacting behaviors, and lessening the psychological damage caused by fear and isolation. |
| 32377638 | To date, there is no specific vaccine against the causative virus, SARS-CoV-2, nor is there an effective medicine for treating COVID-19, thus raising concerns with respect to the effect of risk factors such as clinical course and pathophysiological parameters on disease severity and outcome in patients with COVID-19. |
| 32377709 | To date, COVID‑19 has infected more than 3,000,000 people worldwide and killed more than 200,000 people. |
| 32378464 | A summary of available clinical guidelines with recommendations is presented, to provide community nurses with the up-to-date information required for protecting individuals living with a number of long-term conditions. |
| 32378471 | Much more serious than SARS-CoV in 2002, the current SARS-CoV-2 infection has been spreading to more than 213 countries, areas or territories and causing more than two million cases up to date (17 April 2020). |
| 32378648 | We provided a rapid review to critically assess the potential anti-coronavirus effect of remdesivir on COVID-19 and other coronaviruses based on the most up-to-date evidence. |
| 32379077 | Additionally, limited recommendations to date have been issued regarding scene investigative protocol, and there are a paucity of publications characterizing COVID-19 postmortem gross and histologic findings. |
| 32380582 | However, to date, knowledge, no observational study on spine surgeries during the pandemic has not been reported. |
| 32381442 | We highlight the value of engaging in humanitarian medical work, contributions of the hip and knee arthroplasty community to date, and future needs after the resolution of the pandemic. |
| 32382737 | To date, real-time RT-PCR is the only test able to confirm this infection. |
| 32384153 | With a run time of 15 to 20 minutes and first results being available in under 7 minutes for high RNA concentrations, the reported assay constitutes one of the fastest nucleic acid based detection methods for SARS-CoV-2 to date and may provide a simple to use alternative to RT-qPCR for first-line screening at the point of need. |
| 32384397 | Thirty-five children with COVID-19 infection matched for age, sex and date of admission, and who classified as non-severe type, were randomly selected from the hospital admissions. |
| 32385799 | To date, however, no specific recommendations are available for cardiothoracic robotic assisted surgery in COVID-19 positive patients. |
| 32385985 | The outbreak of coronavirus disease 2019 (COVID-19) is serious and there is no effective treatment to date. |
| 32386435 |
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| 32387384 | The initial phase of the epidemic, from February 17th to March 23rd, 2020, is used to estimate the contact rates, infectious periods and mortality rate using both confirmed cases (by date of symptoms initiation), and daily mortality. |
| 32387562 | To date, the coding potential of SARS-CoV-2 remains partially unknown. |
| 32387564 | The first whole genome sequence was published on January 5 2020, and thousands of genomes have been sequenced since this date. […] We identify regions of the SARS-CoV-2 genome that have remained largely invariant to date, and others that have already accumulated diversity. |
| 32389150 | SARS-CoV-2, has been implicated in the largest recorded CoV outbreak to date.Initially the majority of COVID-19 cases were in China, but the virus has spread to more than 184 countries worldwide with the United States currently having more cases than any other country. |
| 32389538 | The service to date has been shown to be effective, safe, largely reproducible and reflective. |
| 32389893 | To date, the literature has predominantly consisted of case reports, case series, and systemic protocols for dealing with this deadly disease from a plethora of specialties with larger observational and randomized studies only now starting to emerge. |
| 32391369 | The literature to date does not fully support the routine use of corticosteroids in COVID-19, but some findings suggest that methylprednisolone could lower mortality rate in more severe forms of the condition. |
| 32392282 | The date of final follow-up was April 24, 2020. |
| 32392288 | While there is evidence that the burden of COVID-19 infection in hospitalized children is lesser than in their adult counterparts, to date, there are only limited reports describing COVID-19 in pediatric intensive care units (PICUs). |
| 32393147 | The groups that enable these inspirational collaborative accomplishments through their dedication, innovation, and imagination are the practicing physicians who have given freely and generously of their time and talents to help the whole health care community provide the most up-to-date care possible. |
| 32393394 | In these three MRT applications, potential cases of word misuse were evaluated by the regulator who then notified the practitioner to comply with existing regulations by a specific date. […] The MRT was then used on that date to determine compliance. |
| 32393973 | The case presentation is followed by a review of the literature to date on COVID-19 in regard to inflammatory bowel disease and pregnancy, respectively. |
| 32395909 | Medline was systematically searched using PubMed (search date March 19, 2020) for relevant studies in accordance with PRISMA guidelines. |
| 32397511 | To date, it is unclear why some patients develop severe symptoms. |
| 32397688 | To address this global crisis, up-to-date information on viral genomics and transcriptomics is crucial for understanding the origins and global dispersion of the virus, providing insights into viral pathogenicity, transmission, and epidemiology, and enabling strategies for therapeutic interventions, drug discovery, and vaccine development. |
| 32398569 | In this review, we summarize the epidemiologic and clinical features of children infected with SARS-CoV-2 reported in pediatric case series to date. […] Children rarely needed admission to intensive care units (3%), and to date, only a small number of deaths have been reported in children globally. |
| 32399507 | We estimated the reproduction number, R, during the early transmission phase in Lima from the daily series of imported and autochthonous cases by the date of symptoms onset as of March 30th, 2020. […] Prior to the implementation of the social distancing measures in Lima, the local incidence curve by the date of symptoms onset displays near exponential growth dynamics with the mean scaling of growth parameter, p, estimated at 0.9 (95%CI: 0.9,1.0) and the reproduction number at 2.3 (95% CI: 2.0, 2.5). |
| 32399515 | On the same date (also the date of this review), Africa had reported 5,999 confirmed cases, of which 3,838 (almost 65%) occurred in South Africa, Algeria, Egypt, Morocco and Tunisia, with the remaining 2,071 cases distributed unevenly across the other African countries. |
| 32399995 | To date, no study attempted to quantify the impact of the Covid-19 outbreak on incidence and treatment of acute stroke. |
| 32402329 | In the present paper, we provide an up-to-date review of the literature currently available on animal CoVs, focusing on the molecular mechanisms that are responsible for the emergence of novel CoV strains with different antigenic, biologic and/or pathogenetic features. |
| 32403261 | To date, most of the effective hand sanitizer products are alcohol-based formulations containing 62%-95% of alcohol as it can denature the proteins of microbes and the ability to inactivate viruses. |
| 32404225 | The country’s “go hard, go early” policy serves as an exemplar for the rest of the world to date. […] Though there has been no significant rise in referrals to secondary mental health services to date (4 May 2020), a rapid surge in mental health presentations is widely anticipated. |
| 32404257 | In the absence of concrete economic measures to date, and the scenario of economic uncertainty, we conclude that it is not possible to prevent gender-based violence in a comprehensive way, without considering the increase in unemployment, temporary and instability employment, economic dependency or the overload of household chores and reproductive tasks, among other elements that facilitate it. |
| 32404498 | We should adapt CME sessions to keep trainees up to date with core clinical competencies as they will continue to manage both COVID-19 and non-COVID-19 cases and this pandemic may last until year’s end. |
| 32404630 | To date there was one minor bleeding due to postoperative therapeutic anticoagulation. |
| 32405603 | Extracted data included author; date; study design; country; patient demographics; number of participants in severe and non-severe disease groups; prevalence of clinical gastrointestinal symptoms such as vomiting, nausea, diarrhoea, loss of appetite, abdominal pain, and belching; and digestive system comorbidities including liver disease and gastrointestinal diseases. |
| 32406374 | To date, the literature is widely heterogeneous regarding the loss of smell; therefore, we advise home isolation measures and/or social distancing, and to carry out diagnostic tests for SARS-CoV-2 when possible in those patients with sudden and severe loss of smell who cannot be promptly evaluated. |
| 32408547 | To date, there is no specific drug registered to combat the disease it causes, named coronavirus disease 2019 (COVID-19). |
| 32410225 | We urge policy-makers to ensure that nurses’ voices and perspectives are integrated into both local and global decision-making so as to minimize the structural injustices many nurses have faced to date. |
| 32410714 | The duration from the date of ICU admission to the study date was 11 (5-17) days, and the duration from onset of symptoms to the study date was 31 (24-36) days. |
| 32410913 | Children have had a relatively lower rate and a less serious course of infection as reported in the literature to date. |
| 32412509 | To date, there is no specific therapy for SARS-CoV-2 infection. |
| 32413112 | This estimate of excess cases represents 30.4% of the 716 total cases in those Iowa counties by that date. |
| 32413502 | In this comprehensive and up to date review we assess changes to working practices through the lens of each surgical specialty. |
| 32414522 | To the best of our knowledge, there was only one literature to date documented SARS-CoV-2 induced rhabdomyolysis as a late complication of COVID-19 patient. |
| 32414622 | To date, Coronavirus Disease 2019 (COVID-19) has affected at least 100,000 individuals worldwide, reaching thousands of mortalities (Zhou et al., 2020; World Health Organization, 2020). |
| 32414678 | To date, April 12, 2020, the virus has reached 209 nations, affecting 1.8 million people and causing more than 110,000 deaths. |
| 32415519 | Measures therefore need to be taken concerning the transmission of up to date and accurate information to medical students. |
| 32415860 | To date, data are limited regarding the trend of liver biochemistries over the course of illness. |
| 32416074 | Notably, RmYN02 shares 93.3% nucleotide identity with SARS-CoV-2 at the scale of the complete virus genome and 97.2% identity in the 1ab gene, in which it is the closest relative of SARS-CoV-2 reported to date. |
| 32416357 | Although to date, and by obvious reasons, the number of studies on this issue are still scarce, most results indicate that chronic exposure to air pollutants delays/complicates recovery of patients of COVID-19 and leads to more severe and lethal forms of this disease. |
| 32416785 | As a reference group, we randomly sampled ten patients per case, individually matched for age, sex, region (ie, Madrid), and date of admission to hospital (month and day; index date), from Base de datos para la Investigación Farmacoepidemiológica en Atención Primaria (BIFAP), a Spanish primary health-care database, in its last available year (2018). […] We extracted information on comorbidities and prescriptions up to the month before index date (ie, current use) from electronic clinical records of both cases and controls. |
| 32416984 | We review our experience with the virus to date, our strategic approach to burn center function under these circumstances, and lessons learned. |
| 32417380 | Final date of follow-up was May 7, 2020. |
| 32417802 | The COVID-19 pandemic represents the greatest challenge to date faced by the medical community in the 21st century. |
| 32418278 | Hence, there is a need for simple, digestible, up-to-date, and accurate information on COVID-19 that is electronically disseminated and easy to obtain. |
| 32418715 | To date, no specific therapeutic drugs or vaccines are available to treat COVID-19 patients. |
| 32418793 | The 2013-2016 West Africa EBOV epidemic was the biggest EBOV outbreak to date. |
| 32419769 | To date, there have been zero incidences of radiographer healthcare worker transmission within our institution during the course of work. |
| 32420652 | To date, the coronavirus (COVID-19) outbreak that started in Wuhan, in the Hubei province of China, in late December 2019 seems to be eclipsing all of these previous infectious diseases in terms of its global reach and impact (Wang, Horby, Hayden, & Gao, 2020). |
| 32420921 | Italy is one of the most afflicted Country by this epidemic with 136,110 confirmed cases and 16,654 deaths on 9.4.2020 (at the same date, the Ministry of Health was reporting 143,626 cases). |
| 32420923 | From that date, the Regional Emergency Medical Services (EMS) Trust (AREU) of the Lombardy region decided to apply Business Intelligence (BI) to the management of EMS during the epidemic. |
| 32421292 |
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| 32421858 | A systematic review showed there was insufficient evidence to support the exclusive use of either CBEs or OBEs in assessment, however the studies conducted to date have rarely looked at high-stakes assessments due to concerns about the validity of OBEs1 . |
| 32422341 | The search strategy included clinical date published until May 9, 2020. |
| 32423922 | Every month, DTB scans sources of information on treatments, disease management and other healthcare topics for key items to bring to our readers’ attention and help them keep up to date. |
| 32425316 | This article, therefore, presents a critical review of hand sanitation approaches and products available on the market in light of the scientific evidence available to date. |
| 32425470 | To date, most of the medical literature, including Center for Disease Control guidelines, has relied on three necessary symptoms in making the diagnosis of COVID-19: fever, cough and shortness of breath. |
| 32425484 | From all the documents located, information was extracted on the date of publication, country of publication, type of study, assessment of the level of evidence and degree of recommendation, and results of interest to answer the research question. |
| 32425486 | A bibliographic search was conducted in the Medline, CINAHL, Scopus and WOS main databases, with no date limit and using the keywords “transmission”, “infection”, “contagious”, “spreads”, “coronavirinae”, “coronavirus”, “COVID 19”, “sars cov 2”, “nurses” and “nursing”. |
| 32425490 | A bibliographic search was made, without date limit, in Medline, CINAHL, PsycINFO, Scopus and Web of Science databases using the following keywords: “emotional management”; “health crisis” and “health crisis response”. |
| 32425663 | Published reports to date suggest that perinatal transmission of SARSCoV- 2 can occur but is rare. |
| 32426202 | VANISH has been utilized regularly in an anesthesia practice of 30+ providers and, to date, there have been no documented COVID-19 infections. |
| 32426864 | Up to date, a total of 1177 COVID-19 patients have been hospitalized. |
| 32427103 | To date, no work has assessed how this guidance differs across governments. |
| 32428207 | The median time to seropositivity observed for a reactive IgM and IgG result from the date of a positive PCR was 5 days (IQR: 2.75-9 days) and 4 days (IQR: 2.75-6.75 days), respectively. |
| 32429249 | When reviewing the literature it became obvious that keeping up-to-date with all relevant publications is almost impossible. |
| 32429679 | It would aid in emphasizing the up-to-date situation in a nutshell and the measures taken by the health sector of Pakistan to abate the risk of communication. |
| 32430286 | Here we review what is currently known on the mechanisms of action of CQ and HCQ as anti-viral, anti-inflammatory and anti-thrombotic drugs and discuss the up-to-date experimental evidence on the potential mechanisms of action of CQ/HCQ in Sars-Cov2 infection and the current clinical knowledge on their efficacy in the treatment of COVID-19 patients. |
| 32430459 | Based on one of the largest genome-wide association studies on type 2 diabetes mellitus (T2DM) to date (N = 898,130), T2DM was causally linked to raised ACE2 expression (P = 2.91E-03; MR-IVW). |
| 32430840 | To date, non-pharmacological interventions (NPI) have been the mainstay for controlling the coronavirus disease-2019 (COVID-19) pandemic. […] We employed a multivariate prediction model, based on up-to-date transmission and clinical parameters, to simulate outbreak trajectories in 16 countries, from diverse regions and economic categories. |
| 32430957 | We conducted a comprehensive literature search using PubMed, EMBASE, the Cochrane Library, China National Knowledge Infrastructure Database and Wan Fang Data until 20 April 2020 (studies were identified through PubMed alert after that date). […] Exclusion criteria were non-peer-reviewed or unpublished reports, unspecified date and location of the study, suspicion of duplicate reporting, and unreported maternal or perinatal outcomes. |
| 32431120 | The aim of the present study is to review the up-to-date professional literature dealing with the psychological impact of a pandemic outbreak on medical staff. |
| 32432217 | To date the FDA has given emergency use authorization (EUA) to 48 COVID-19 in vitro diagnostic tests and 21 high complexity molecular-based laboratory developed tests, as well as implemented policies that give broad authority to clinical laboratories and commercial manufacturers in the development, distribution, and use of COVID-19 diagnostic tests. |
| 32433345 | To date, several direct anti-SARS-CoV-2 agents have demonstrated promising in vitro and clinical efficacy. |
| 32433799 | According to the largest case series to date, most of the symptomatic patients complain of a mild respiratory syndrome (81%), while approximately 14% develop a severe disease requiring hospitalization and a further 5% need intensive care3 . |
| 32434788 | To date, there is no effective treatment. |
| 32436005 | In this study it is aimed to identify the up-to-date practice patterns related to preoperative evaluation and anesthesia for stone disease interventions during COVID-19 pandemic. |
| 32437052 | The data were obtained from the website of health organizations of 36 European countries and the website of WHO until the date of May 11, 2020. |
| 32437340 | Changes in vaccine doses administered to children and the effects of those changes on up-to-date status were examined for vaccinations recommended at milestone ages corresponding to the end of an Advisory Committee on Immunization Practices (ACIP) recommendation period for one or more vaccines (4). |
| 32437912 | To date, globally, over 30,000 people have died from this emerging disease. |
| 32437930 | We considered outbreak information where the first case registered in Marche with onset symptoms (26 February 2020) to the present date (20 April 2020). |
| 32438330 | As on date, no specific treatment is available for devastating COVID-19 (SARS-CoV-2) infection. |
| 32438579 | There were some family infections of coronavirus disease 2019 (COVID-19) in Taiwan to date. |
| 32440666 | To date, only a few studies have reported the distribution of lung lesions by segment. |
| 32441351 | To date, there is a paucity of patient selection criteria and prognosticators to facilitate decision making and enhance precious ICU capacity. |
| 32441666 | The final date of follow-up was March 20, 2020. |
| 32442684 | After this date, 39 patients with a diagnosis of cancer were operated on in our clinic. |
| 32443459 | To date, assays based on the reverse-transcription polymerase chain reaction (RT-PCR) in respiratory samples are the gold standard for COVID-19 diagnosis. […] To date, few studies have been conducted concerning the potential utilization of rapid testing for COVID-19, with some conflicting results. […] We can conclude that: (1) rapid diagnostic tests for COVID-19 are necessary, but should be adequately sensitive and specific; (2) few studies have been carried out to date; (3) the studies included are characterized by low numbers and low sample power, and (4) in light of these results, the use of available tests is currently questionable for clinical purposes and cannot substitute other more reliable molecular tests, such as assays based on RT-PCR. |
| 32443871 | With this prediction model, the overall infections, the infection peak, and date can accurately be predicted one week before they occur. |
| 32444366 | The final date of follow up was 5 May 2020. |
| 32444393 | The final date of follow-up was March 19, 2020. |
| 32444460 | Overall, 41% (8199/20 133) of patients were discharged alive, 26% (5165/20 133) died, and 34% (6769/20 133) continued to receive care at the reporting date. 17% (3001/18 183) required admission to high dependency or intensive care units; of these, 28% (826/3001) were discharged alive, 32% (958/3001) died, and 41% (1217/3001) continued to receive care at the reporting date. |
| 32445776 | To date, 23 confirmed cases of infections (0.4% of all HCWs) have been reported in a 30-day observation period. |
| 32445839 | The purpose of this review is to provide information, up-to-date as of the date of submission of the manuscript to the journal, on the various tests that have been developed, their scientific basis and their interpretation. |
| 32447630 | This review addresses the preliminary observations regarding the neurological disorders reported with COVID-19 to date and describes some of the disorders that are anticipated from prior experience with similar coronaviruses. |
| 32449192 | With over 4 700 000 infections to date across 188 countries and more than 310 000 deaths worldwide over the course of just 5 months, we were remarkably unprepared.[ |
| 32449374 | To date, more comprehensive systematic reviews of laboratory findings on COVID-19 are missing. |
| 32450087 | To-date, there has not been a clear signal suggesting that asthma or treatment with inhaled steroids are a risk factor for severe COVID-19 disease. |
| 32450344 | To date, specific indications to treat this condition are lacking. |
| 32450631 | Excel was used to describe the relationship between clinical classification and age distribution, contact history and date of onset. |
| 32451162 | The last date of research for this study was April 4, 2020. |
| 32451260 | To date, there have been more than 2.3 million confirmed cases and more than 160,000 deaths globally caused by COVID-19. |
| 32451301 | Up to date, there are no reported deaths in pregnant women with Covid-19, while in the cases that have presented pneumonia because of Covid-19, the symptoms have been moderate and with a good prognosis in recovery. |
| 32451351 | We agree with the authors that, despite conflicting clinical data to date, it is possible that HCQ may have a protective effect in the setting of COVID-19. |
| 32451367 | There is great uncertainty regarding how countries’ characteristics will affect the spread of the epidemic; to date, there are few studies that attempt to predict the spread of the epidemic in African countries. |
| 32451808 | This global pandemic has affected almost the whole planet and caused the death of more than 315,131 patients as of the date of this article. |
| 32452050 | In this review, we provide a comprehensive and up-to-date overview of the different types of Clinical and Para-clinical diagnostic methods and their practical features, which can help understand better the applications and capacities of various diagnostic approaches for COVID-19 infected cases. |
| 32452804 | To our knowledge, this infoveillance study employs the largest, most comprehensive, and most fine-grained social media data to date to predict COVID-19 case counts in mainland China. |
| 32452888 | Overall mortality to date in this critically ill cohort is 30.9% (67/217) and 60.4% (131/217) patients have survived to hospital discharge. |
| 32453411 | The modelled epidemic with the full ban fitted the observed incidence of cases well, predicting 57 cases on March 6th in Australia, compared to 66 observed on this date, however we did not account for imported cases from other countries. |
| 32453494 | To date, few investigations have been carried out to ascertain the presence of SARS-CoV-2 in the seminal fluid with contrasting results. |
| 32454808 | No breast milk samples were positive for SARS-CoV-2 and, to date, there is no evidence on the presence of SARS-CoV-2 in breast milk of pregnant women with COVID-19. |
| 32454981 | Since no therapies have been formally approved and completely effective and safe to date, the best clinical choice is acquired only after consistent and fair communication and collaboration between licensed clinicians, researchers, regulatory authorities, manufacturers and patients. |
| 32455517 | Up to date there is little known regarding the impact of this outbreak on spinal specialists’ daily clinical practice. |
| 32455534 | To this date, no specific drugs or vaccines are available to treat SARS-CoV-2 despite its close relation to the SARS-CoV virus that caused a similar epidemic in 2003. |
| 32455859 | To date, despite no universal guidelines are available for dental procedures in pediatric dentistry during COVID-19 outbreak, routine dental practice should be postponed and only severe dental emergencies must be treated. |
| 32456944 | Most cases are managed as outpatients, however severe symptoms are also appearing and mortality to date is 16.2%. |
| 32457048 | We conducted a comparative cohort study of patients with rheumatic disease and COVID-19 (confirmed by severe acute respiratory syndrome coronavirus 2 PCR), compared in a 1:2 ratio with matched comparators on age, sex and date of COVID-19 diagnosis, between 1 March and 8 April 2020, at Partners HealthCare System in the greater Boston, Massachusetts area. |
| 32458712 | Only 187 urine samples have been reported to have been tested in the literature to date despite over 4 million cases of respiratory Covid 19 positive cases being reported worldwide. |
| 32459192 | The International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Task Force on COVID-19 has been established to synthesize up-to-date information on the epidemiology, pathogenesis, and laboratory diagnosis and monitoring of COVID-19, as well as to develop practical recommendations on the use of molecular, serological, and biochemical tests in disease diagnosis and management. |
| 32459675 | First, they propose delaying the date that programs can access applicant data through the Electronic Residency Application Service, thereby affording students more time to complete clinical experiences, solidify their specialty decision, and strengthen their residency application. |
| 32460208 | Unfortunately, to date, there is no specific antiviral treatment for COVID-19. |
| 32461194 | This article, therefore, presents a critical review of hand sanitation approaches and products available on the market in light of the scientific evidence available to date. |
| 32462701 | These infection models have already been useful for studies of transmission and immunity, but to date only partially model the mechanisms implicated in human severe COVID-19. |
| 32462756 | A total of 166 patients receiving colorectal surgery from 20th December 2019 to 20th March 2020 at Department of General Surgery in Chinese General Hospital of People’s Liberation Army were enrolled, and further divided into two groups based on before or after admission date of 20th January 2020. |
| 32463377 | On that date there were 134,576 reported cases and 4,981 deaths worldwide. |
| 32463716 | To date, there has not been any broad assessment of urological surgery residency changes and concerns during the COVID-19 pandemic. |
| 32464668 | What explains the anemic global response to date? |
| 32467561 | To date, no vaccines or effective drugs have been approved to prevent or treat COVID-19 and the current standard care relies on supportive treatments. |
| 32468508 | To date there are no studies in the literature that demonstrate its feasibility and efficacy in the context of the worldwide SARS-CoV-2 epidemic. |
| 32470120 | In regression analyses controlling for demographic variables and survey date, older adult age was associated with perceiving larger risks of dying if getting COVID-19, but with perceiving less risk of getting COVID-19, getting quarantined, or running out of money, as well as less depression and anxiety. |
| 32470470 | There are over 2118 on-going clinical trials underway, but to date none of these drugs have consistently proven effective. |
| 32471004 | The manifestations of COVID-19 in solid organ transplant recipients are only beginning to be understood with cases reported to date in transplant recipients on chronic immunosuppression. |
| 32471009 | There are now over 1 million confirmed cases of COVID-19 globally with more than 270,000 recorded deaths to date. |
| 32472683 | Although RNA has been detected in various clinical samples, no reports to date have documented SARS-CoV-2 in human milk. |
| 32472687 | Characteristics of each season, including the rate of influenza-like illness (ILI), duration of epidemic, date of termination of epidemic, distribution of influenza virus strain and hospitalization were analyzed. |
| 32473007 | To date, no specific estimate of R0 for SARS-CoV-2 is available for healthcare settings. |
| 32473151 | Limited data exists to-date on the laboratory findings in children with COVID-19, warranting the conduction of this study, in which we pool the currently available literature data on the laboratory findings seen in children with mild and severe COVID-19. |
| 32474026 | Till date, no drug has been approved for the treatment of this infection. |
| 32474093 | Indeed, in this review we discuss several neurologic aspects reported in the literature to date including the evidence and pathways of neuroinvasion in COVID-19 and the main neurologic disorders reported in the literature to date, as well as future perspectives and the potential long-term consequence of current neuroinfection in COVID-19 patients. |
| 32474860 | The last follow-up date was Feb. |
| 32476001 | In fact, within the SECURE-IBD database, there have been only 4 Greek IBD patients, to date, who have been reported as positive for SARS-CoV-2. |
| 32476394 | It was found out that to date there is very little data on the state of loro organs in patients with SARS-CoV-2 and no data on anosmia in the pediatric population. |
| 32476607 | Results were analysed in combination with sera collection date and clinical information. |
| 32476796 | In this review, we summarize the data on GI involvement to date, as well as the impact of COVID-19 on underlying GI diseases. |
| 32479246 | To date, no specific treatment has been proven to be effective for coronavirus disease 2019 (COVID-19). |
| 32479632 | To date, no report on COVID-19 pediatric patients in a large urban center with data on underlying comorbidities and co-infection for hospitalized cases has been published. |
| 32479766 | To date no evidence confirmed COVID-19 vertical transmission from infected pregnant mother to their fetus. |
| 32479816 | SARS-CoV-2 infection in pregnant women does not lead to fetus mortality, unlike other zoonotic coronaviruses such as SARS-CoV and MERS-CoV, and there is, to date, no evidence of intrauterine transmission to neonates. |
| 32481690 | This is especially true for the newly identified COVID-19 caused by SARS coronavirus 2 (SARS-CoV-2) for which, to date, no specific antiviral drugs or vaccines have been approved. |
| 32481719 | We summarize the most up-to-date information on the role of miRNAs in ASL homeostasis and host-pathogen interactions in the airway and discuss concepts for miRNA-directed therapy. |
| 32485299 | Using the Medicare POSPUF database, aerosol-generating procedures (AGPs) were mapped based on hospital referral regions, against up-to-date COVID-19 case distribution data, as of April 24, 2020. |
| 32490842 | This up-to-date analysis may elucidate the evolution of the COVID-19 pandemic in Italy. |
| 32490972 | The evidence generated on COVID-19 and ophthalmology to date is limited, although this is understandable given the circumstances. |
| 32491297 | To date the European experience with COVID-19 mortality has been different to the observed in China and Asia. […] We have adapted our predictive model of COVID-19-related mortality, which rested on the observed mortality within the first weeks of the outbreak and the date of the respective lockdown in each country. |
| 32492529 | To date, our hospital has treated thousands of COVID-19 positive patients and sits at the forefront of the United States response to this pandemic. |
| 32493447 | The name of the trial register is Iranian registry of clinical trial (IRCT), registration number is IRCT20120826010664N6, date of trial registration is April 7, 2020, FULL PROTOCOL: The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). |
| 32493460 | The protocol version number is 1.0 and the date is 18 May 2020. |
| 32493466 | Here we estimate the effective reproduction number, Rt, of COVID-19 in Singapore from the publicly available daily case series of imported and autochthonous cases by date of symptoms onset, after adjusting the local cases for reporting delays as of March 17, 2020. |
| 32493468 | Secondary outcomes include mortality from the date of randomization until the last day of the study which will be the day all of the patients have had at least one of the following outcomes: 1) Improvement of two points on a seven-category ordinal scale. […] Duration of hospitalization from date of randomization until the date of hospital discharge or date of death from any cause, whichever comes first. […] Incidence of new mechanical ventilation uses from date of randomization until the last day of the study. […] Recruitment is finished, the start date of recruitment was on 9th April 2020 and the end date was on 14th April 2020. |
| 32493475 | Primary outcome will be measured until the end of treatment for each participant (until the date of the last dose taken by each patient). […] EU Clinical Trials Register: 2020-001530-35; Date of trial registration: 13th of April 2020; https://www.clinicaltrialsregister.eu/ctr-search/trial/2020-001530-35/ES FULL PROTOCOL: The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). |
| 32493478 | Protocol version: 1.2 05 April 2020 Recruitment is ongoing, started March 31 and anticipated end date is September 30, 2020. […] ClinicalTrials.gov, Protocol Registry Number: NCT04328961 Date of registration: April 1, 2020, retrospectively registered FULL PROTOCOL: The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). |
| 32493740 | To date, persuasive evidence of important benefit in COVID-19 does not exist for any antiviral treatments, although for each treatment evidence has not excluded important benefit. |
| 32494546 | To date, there is no approved targeted treatment, and many investigational therapeutic agents and vaccine candidates are being considered for the treatment of COVID-19. |
| 32494567 | To date (17th April 2020) a total of 2,230,439 cases of COVID-19; 150,810 cases of deaths and 564,210 recovered cases have been reported worldwide. […] To date, there is no vaccine or no specific treatment for COVID-19. |
| 32494931 | To date, there is no licensed treatment or approved vaccine to combat the coronavirus disease of 2019 (COVID-19), and the number of new cases and mortality multiplies every day. |
| 32495333 | Taiwan’s success to date is grounded in proactive preparedness and deployment by the government and effective teamwork among government agencies, medical institutions, enterprises, and the public. |
| 32496101 | Health care providers are experiencing potentially morally injurious events that may violate their moral code or values, yet almost no research has been conducted on moral injury among health care providers to date. |
| 32496357 | Only 1 mortality (4.8%) to date, in a critically-ill heart/kidney patient who had been in the ICU prior to diagnosis. |
| 32496919 | Yet, despite an explosion in the number and availability of serologic assays to test for antibodies against SARS-CoV-2, most have undergone minimal external validation to date. |
| 32497806 | Optimal management of infectious diseases is guided by up-to-date information at the individual and public health level. |
| 32498138 | We measured the period from the date of illness onset to the date of COVID-19 confirmation. […] The estimated median period between the date of symptom onset and the date of COVID-19 confirmation was 4 days (95% confidence interval, 1-12). […] There was a delay in COVID-19 confirmation from the date of illness onset among the cases linked to the Shincheonji religious group. |
| 32498503 | Approximately 1,016,128 reported cases, 211,615 recovered cases and 53,069 deaths of COVID-2019 have been reported to date (April 2, 2020). |
| 32498731 | The relative search volume was obtained for ‘Coronavirus’, ‘handwashing’, ‘face mask’ and symptom related keywords, for the United Kingdom, from the date of the first confirmed case until numbers peaked in April. |
| 32498752 | Average preventive measure interest was calculated for the query terms “hand sanitizer,” “hand washing,” “social distancing,” and “COVID testing.” We then calculated the delay in statewide SAH orders from March 1, 2020, to the date of issuance and by-state presidential voting percentage. |
| 32499154 | The viruses remain a threat till date and are of serious concern since no vaccine or specified drug therapy has been approbated for treating human coronaviruses. |
| 32499832 | To date, clinical evidence and guidelines based on reliable data and randomized clinical trials for the treatment of COVID-19 are lacking. |
| 32500648 | In this manuscript, our goal was to provide a “up-to-date” account on this topic, through analysis of current literature and sharing our experiences during this pandemic. |
| 32501378 | The latest version of human coronavirus said to be COVID-19 came out as a sudden pandemic disease within human population and in the absence of vaccination and proper treatment till date, it daunting threats heavily to human lives, infecting more than 12, 11, 214 people and death more than 67, 666 people in 208 countries across the globe as on April 06, 2020, which is highly alarming. […] When no treatment or vaccine is available till date and to avoid COVID-19 to be transmitted in the community, social distancing is the only way to prevent the disease, which is well taken into account in our novel epidemic models as a special compartment, that is, home isolation. |
| 32501397 | To date the potential impact of previous infection history has been poorly investigated as a potential determinant of risk. |
| 32502054 | The patient reported in this case report is the youngest case reported in Chengdu, China to date. |
| 32502319 | At the date of writing this editorial, there is now agreement amongst experts that the first wave of the United Kingdom’s (UK) COVID-19 pandemic is in decline (1). |
| 32503304 | To date, data on COVID-19-related death cases among physicians from different medical specialties are incomplete and scattered. |
| 32503352 | Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe respiratory illness in humans; the second-largest and most deadly outbreak to date occurred in Saudi Arabia. |
| 32503620 | Recruitment began on 20/03/2020 and the date by which the recruitment is anticipated to be completed is 30/05/2020. |
| 32503657 | Trial participants, investigators, care givers, outcome assessors, and date analysts are not blinded to group assignment. 210 patients are expected to be enrolled and allocated according to the ratio of 2 (Favipiravir group, n=140): 1(regular treatment group, n=70). […] Protocol version number 3.0, 10th April 2020 First Patient, first visit 17th March 2020; recruitment end date anticipated June 1, 2020. |
| 32503874 | The secondary endpoints will be proportion of participants relieved from clinical symptoms defined at the time (in hours) from initiation of the study treatment, all-cause mortality, discharged date, frequency of respiratory progression and treatment-emergent adverse events. |
| 32504135 | To date, no report on LU and neonates with SARS-CoV-2 infection has been published.What is new:• This study adds evidence about LU findings in neonates with SARS-CoV-2 infection. |
| 32505220 | We describe China’s strategies for prevention and control of COVID-19 (containment and suppression) and their application, from the perspective of the COVID-19 experience to date in China. |
| 32505678 | We analyzed our surgical practice since March 14th when the lockdown was declared up to date, May 14th (2 months). |
| 32506109 | Pandemic enveloped RNA Novel Corona Virus’ 2019 (SARS-CoV-2) appears as a beating reed which induce overwhelming outbreak all over the world since November 2019 to till date. |
| 32507006 | We describe our experience as the Division of Arthroplasty in the hospital at the epicenter of the COVID-19 pandemic in Singapore.Patients and methods - The number of COVID-19 cases reported both nationwide and at our institution from February 2020 to date were reviewed. |
| 32507030 | To date, the reasons for this have been generically attributed to old age and underlying diseases. |
| 32507546 | To date, there are varying levels of agreement on the optimal triaging of urologic oncology cases. |
| 32509205 | The current study reviewed published evidence of clinical interventions of severe and critical COVID-19, aiming to provide an up-to-date reference for further clinical treatment. |
| 32510978 | In this review, we highlight what is known to date about coronavirus disease 2019 and cardiovascular risk, focusing in on the putative role of the endothelium in disease susceptibility and pathogenesis. |
| 32511245 | Although double-membrane vesicles (DMVs) appear to be a pan-CoV RO element, studies to date describe an assortment of additional CoV-induced membrane structures. |
| 32511692 | The final date of follow-up was May 22, 2020. |
| 32511859 | The ongoing COVID-19 pandemic has to date infected more than one million people and led to tens of thousands of deaths across the globe. |
| 32511912 | To date, no drug or vaccine has been approved to treat the severe disease caused by this coronavirus, COVID-19. |
| 32511989 | It resulted in the maintenance of a high-volume, high-quality thoracic surgical oncology program with no Covid-19 positive cases to date. |
| 32512950 | To date, there are no specific antiviral agents available for this disease, currently known as COVID-19. |
| 32513062 | Our multidisciplinary team, at the suggestion of a parent, hosted 3 virtual “town halls” in which families could ask questions directly of pediatric otolaryngology, pediatric pulmonology and case management in order to efficiently obtain factual evidence-based up-to-date advice. |
| 32513231 | Date of trial registration: April 10, 2020 FULL PROTOCOL: The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). |
| 32513299 | Trial participants, investigators, care givers, outcome assessors, and date analysts are not blinded to group assignment. 750 patients are expected to be enrolled and the cases are allocated according to the ratio of 2 (Anluohuaxian combined with regular treatment group):1 (regular treatment group). […] Actual Study Start Date: April 1, 2020 Estimated Primary Completion Date: June 1, 2020 Estimated Study Completion Date: December 1, 2020 TRIAL REGISTRATION: ClinicalTrials.gov ID: NCT04334265. |
| 32513308 | ClinicalTrials.gov: NCT04359810 Date of trial registration: April 24, 2020 Retrospectively registered FULL PROTOCOL: The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). |
| 32513502 | We collected epidemiological information about «time» (date of onset of symptoms), «place» (zip code), and «person» (gender, age). |
| 32513514 | However, there have been no vaccines approved in the world to date. |
| 32515384 | The current pandemic of COVID-19 has infected around 2.5 million people with more than 125,000 deaths across the globe till date, and numbers are still rising. |
| 32515404 | Here, we present an overview of the clinical trials that are currently being conducted or have concluded to date on COVID-19 globally. […] Collectively, there are 1,528 trials reported for COVID-19 to date. |
| 32516704 | A plethora of treatments has been or is being assessed, but to date, none has been proven effective. |
| 32516817 | Guidance has come from expert opinion, professional societies and public health agencies, but to date, there is no report on how obstetrical practices have adapted these recommendations to their local situations. |
| 32517882 | To date, no effective vaccine is available which can combat the infection caused by this virus. |
| 32518743 | Although a number of improvement measures are ongoing, however, no study to date has addressed Rohingyas’ self-adopted strategies to mitigate disaster risks. |
| 32520031 | To date, no specific drug has been discovered for the treatment of COVID-19 and hence, people are in a state of anxiety. |
| 32520135 | Medical Uniforms date back from medieval times. |
| 32520235 | We chose the date of the first COVID-19 case to April 25, 2020, as the training period, and April 26 to May 3, 2020, as the test period. |
| 32520285 | In order to account for the stage of the pandemic, the baseline date was defined as the day in which the 10th death was reported. |
| 32521062 | To date there is limited information on how COVID-19 affects patients with a history migraine. |
| 32521557 | About 70 % of patients seem to experience a reduction of smell and taste in the course of the disease, with most of the studies published to date based on questionnaires and anamnestic data. […] A distinction between taste and taste disorders, i. e. a distinction between retronasal aroma taste and the olfactory system from the dysfunction of taste capsules and the further cranial nerves, was mostly not made in the studies available to date. |
| 32522513 | While much of the emphasis in obstetrics and gynecology to date has been on the as yet uncertain impacts of COVID-19 in pregnancy and on changes to surgical management, the pandemic has broad implications for ambulatory gynecologic care as well. |
| 32523137 | To date there are nearly 3 million people infected and more than 250,000 deaths caused by the disease worldwide. […] In Mexico, the first case was detected in February 2020, and to date there are 26,616 confirmed cases and 2,961 deaths throughout the country. |
| 32523927 | Coronavirus disease 2019 (COVID-19) complications include disseminated coagulation and thrombosis, but, to the best of our knowledge, the literature to date on these manifestations has been limited. |
| 32524645 | This process requires up-to-date drug information to ensure optimum use, particularly safety and efficacy profiles of the medications, until convincing evidence is reported. |
| 32524746 | To date, the world is struggling to find a cure/vaccination to this deadly virus. |
| 32525558 | To date, understanding whether acquired immunity and presence of anti SARS-Cov2 antibodies protects against reinfection is one the most important focus of the scientific community [1-2]. |
| 32525707 | Hotline clinicians provided New Yorkers with clinical assessment and guidance, registered them for home symptom monitoring, connected them to social services, and provided a source of up-to-date answers to COVID-19 questions. |
| 32526560 | Details on the onset date of clinical symptoms, throat swab conversion, and course of disease were collected from medical records retrospectively. |
| 32526721 | For countries that showed a strong slowdown in the rate of infections we have extrapolated the expected saturation of the total number of infections and the expected final date. |
| 32527257 | To date, an ongoing experimental therapy with monoclonal antibody against the IL-6 receptor in Italy seems to have beneficial effects on severe lung disease and prognosis in patients with Covid-19 infection. |
| 32527341 | The clinical data of COVID-19 patients treated in the Second People’ Hospital of Fuyang City from January 20th to February 18th in 2020 were retrospective analyzed, including the demographic and epidemiological date, vital signs and hematology indexes, etc. on admission. |
| 32529866 | With limited knowledge about SARS-CoV-2, no approved treatment or vaccine is available till date. |
| 32530314 | To date its adoption for Amyotrophic Lateral Sclerosis (ALS) care is still in a preliminary stage. |
| 32530816 | For anosmia and ageusia, we assessed whether the respective GT correlated with Covid-19 cases and deaths both throughout 2020 and specifically before March 16, 2020 (i.e., the date when the media started reporting that those symptoms could be associated with Covid-19). |
| 32531138 | To date, little is known about the viral shedding duration, clinical course and treatment efficacy of COVID-19 near Hubei Province, China. |
| 32531777 | Much of the work carried out to date involves the differentiation of bacterial and viral sources of infection and often the detection of bacterial and viral co-infection. |
| 32532356 | Patients screening commenced on 16th April and an estimated date of the recruitment of the final participants will be around end of July. . |
| 32532596 | At the time of publication, this review offers the most up-to-date recommendations for clinical practitioners in radiology departments, including radiographers. |
| 32532802 | Of countries that have undertaken suppression to date, lower income countries have acted earlier. |
| 32532933 | To date, seven known strains of HCoVs belonging to four genera (i.e., α?, β?, γ, and δ-CoV) have been recognized; the latest one has been identified as the SARS-CoV-2. […] To date, despite the whole world effort to review various aspects of SARS-CoV-2, including epidemiology, clinical manifestations, diagnosis, and treatment options, there are still gaps in the knowledge of this disease and many issues remain unclear. |
| 32532942 | No systematic reviews have been published on this topic to date. |
| 32533062 | Coronavirus infections of multiple origins have spread to date worldwide, causing severe respiratory diseases. […] It has created a severe worldwide outbreak beginning in late 2019, leading to date to over 4 million cases globally. |
| 32533197 | To date, there is no specific treatment for COVID-19 induced AKI. |
| 32533777 | To date, no data have ever been reported to reflect the clinical features of Corona Virus Disease 2019 (COVID-19) among these patients with pre-existing ILD. |
| 32534175 | A hypothetical three-part prevention, diagnostic, and treatment approach based on an up-to-date scientific literature review for COVID-19 is proposed. |
| 32534210 | The clinical outcomes of these operative patients were monitored up to 12 May 2020, the final date of follow-up, a minimum of 15 days after all patients were discharged from the hospital. |
| 32534465 | With the success of slowing disease spread in many countries to date, and reduced workload due to limitations on elective surgery in many institutions, there is more time and opportunity to be proactive in implementing measures to mitigate or minimise potential adverse psychological effects and improve, restore and preserve the wellbeing of the workforce now and for years to come. |
| 32535955 | To date it has resulted in ~6.5 million confirmed cases and caused almost 400,000 related deaths worldwide. |
| 32536205 | The evidence to date indicates that CGM offers promise as an effective tool for monitoring hospitalized patients. |
| 32537425 | To date, no cases of human pancreatitis have been identified as related to a COVID-19 infection, although multiple other gastrointestinal symptoms have been described. |
| 32537561 | This review is correct as of the date published and will be updated as more diagnostic tests come to light. |
| 32538276 | To date, there is no confirmed treatment or vaccine prevention strategy against COVID-19. |
| 32538809 | Review of relevant manuscript published up to date, draft creation correctedt hough modified nominal group until final corrected manuscript. |
| 32540268 | This study considers up-to-date information on the biological determinants shared by COVID-19 and renal disease, and aims to provide evidence-based recommendations for the clinical management of RCC patients with COVID-19. |
| 32540369 | Daily numbers of confirmed cases of each category were plotted by date of onset, and the epidemic form of each category was inferred. |
| 32540737 | There is no evidence to date that pioglitazone upregulates ACE2 in the alveolar cells; rather, there is evidence from animal studies of upregulation of ACE2 in insulin sensitive tissues, which might have a protective effect on lung injury. |
| 32541085 | To date, no medication supported by randomized clinical trials has been approved for the treatment of COVID-19. |
| 32541496 | The evidence to date of Chinese medicine in treatment of coronavirus-related pneumonia will be systematically reviewed and meta-analyzed. |
| 32542188 | To-date (4-22-2020) it affected over 2.6 million people and resulted in nearly 200,000 death worldwide mainly due to severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2). |
| 32542213 | Numerous studies are ongoing focusing on anticytokine therapies, antibiotics, and antiviral agents, but none to date have focused on treating the underlying thrombotic coagulopathy in an effort to improve respiratory failure in COVID-19. |
| 32542402 | It is vital that public health officials provide clear and up-to-date information about protective measures and crucial communications to respond to information-seeking behavior across NYC. |
| 32544281 | To date, no data have ever been reported to reflect the prevalence of Corona Virus Disease 2019 (COVID-19) among these outpatients. |
| 32544725 | However, the present detailed report of up-to-date knowledge on this topic can provide a useful source for further studies focusing on more deepened investigations of SARS-CoV-2 behaviour in the environment. |
| 32544872 | In this commentary we perform a bibliometric review of the available academic literature about COVID-19 in the top 20-ranked ENT journal, with the goal of providing an overview of what has been published to date and encouraging a shift towards quantitative research. |
| 32544884 | There is, however, no effective antiviral drug that can be used to treat COVID-19 to date. |
| 32545925 | To date, there have been reports of neurologic manifestations in COVID-19 patients including ischemic strokes, Guillain-Barre Syndrome and anosmia. |
| 32546458 | The ongoing pandemic of Covid-19 caused by the SARS-CoV-2 virus has infected more than 6 million all over the world and has caused more than 3.8 lakh fatalities till date(1) Health workers are the frontline responders and are exposed to a plethora of health hazards. |
| 32547323 | Rationale: Up to date, the exploration of clinical features in severe COVID-19 patients were mostly from the same center in Wuhan, China. |
| 32547911 | In the opinion of the medical societies of hygiene and pediatrics undersigning the present statement, the analyses published to date regarding transmission of SARS-CoV-2 and the course of CoVid-19 show that children play a much less significant role in the spread of the virus than do adults. […] According to the findings available to date, not only do children and adolescents less frequently fall ill with CoVid-19, they also generally become less severely ill than do adults. |
| 32549076 | To date there is no study that demonstrates or can suggest the ability for a virus to be transmitted during surgical treatment whether open, laparoscopic or robotic. |
| 32549337 | Case confirmation was not performed in all hospitalized patients, but 72.15% of hospitalized patients had favorable outcomes to date. |
| 32549531 | Despite initial difficulties in management of such patients, the constant increase of literature in the field is to date clarifying some questions from clinicians. |
| 32550040 | To date, no evidence shows that ACEIs or ARBs increase the susceptibility and mortality of patients infected with SARS-CoV-2, and hence, it is not advisable to discontinue such drugs in patients with cardiovascular disease. |
| 32552509 | Visit volumes were assessed weekly and practice patterns were compared before and after March 15, 2020, as this was the date of a major statewide stay-at-home order in Ohio. Results: Before March 15 the mean in-person visit per week was 5129.4 and decreased to 866.7 after that date. |
| 32552659 | With the large numbers of undifferentiated patients managed by the ED to date, more than 820 patients with COVID-19 have been identified in the hospital. |
| 32552751 | To date, there is no available literature on the clinical data on COVID-19 patients in Iran. |
| 32552794 | Finally, we estimate the date when the first infected case occurred in Wuhan. […] The date of first infection is estimated as 30 November 2019. |
| 32553503 | In summary, based on the currently available evidences and as recommended by several medical societies, ACEi or ARB should not be systematically discontinued because to date no safety signal was raised with the use of these drugs. |
| 32553562 | Up to date, a lot of reports have shown that olfactory dysfunction is related to viral infections but no exact mechanism, clinical course, and definite treatment have been discovered, which is also same in COVID-19. |
| 32554861 | This study is a retrospective, single-center case series of the 238 consecutive hospitalized patients with confirmed COVID-19 at the First Hospital of Changsha city, China, from 01/21 to 02/14, 2020; the final date of follow-up was 02/27, 2020. |
| 32554901 | The most commonly used CFR is thecase fatality ratio, typically constructed using the estimated number of deaths to date divided by the estimated total number of confirmed infected cases to date. |
| 32555565 | In order to evaluate this trend, we analyzed the literature data published since the beginning of the COVID-19 pandemic to date, in addition to our intensive cardiac care unit (ICCU) experience. |
| 32555974 | Studies carried out to date on possible SARS-CoV2 drug targets highlight glycoprotein S, Mpro (main protease or protease type 3C), and a member of the transmembrane serine protease II families (TMPRSS2). |
| 32556054 | However, non-pharmacological approaches have proven to be the most efficient strategy to date. |
| 32557011 | To date, emerging anti-SARS-CoV-2 treatments are warranted to control epidemics. |
| 32557847 | Since December 2019, SARS-CoV-2 epidemic has spread all over the world.1 To date, few reports regarding the cutaneous involvement in COVID-19 have been published.2,3 Herein, we report a four cases series describing skin lesions probably related with COVID-19. |
| 32558655 | Sixth, following experiences to date in responding to the COVID-19 infodemic and the lessons from other disease outbreaks, infodemic management approaches should be further developed to support preparedness and response, and to inform risk mitigation, and be enhanced through data science and sociobehavioral and other research. |
| 32558877 | ACEI/ARB use was defined as prescription fillings 6 months prior to the index date. |
| 32558916 | Articles were excluded if they did not include specific ventilator allocation recommendations, were in draft status, did not include their state department of health, or were not the most up-to-date guideline. |
| 32559308 | Given the unknown effects that relaxation of social distancing measures will have on the infection rate, we review the evidence to date to see whether a history of haematological malignancy is associated with increased risk of COVID-19. |
| 32559451 | Consistent with previous modelling studies and country-specific COVID-19 responses to date, our analysis estimated that a high proportion of cases would need to self-isolate and a high proportion of their contacts to be successfully traced to ensure an effective reproduction number lower than 1 in the absence of other measures. |
| 32560340 | The high contagiousness of the virus, the strong impact on the health system of the various countries and the absence to date of treatments able to improve the prognosis of the disease make the introduction of a vaccine indispensable, even though there are currently no approved human coronavirus vaccines. |
| 32560745 | Identifier: IRCT20120225009124N4 version 1; Registration date: April 2 2020. |
| 32562316 | To date, the recently discovered SARS-CoV-2 virus has afflicted >6.9 million people worldwide and disrupted the global economy. |
| 32562477 | We finally perform a Monte Carlo simulation with 25,000 runs to evaluate a random uncertainty in the prediction of the date of a substantial reduction in the number of diagnosed daily cases per swab. |
| 32562913 | In 2019, a new coronavirus (SARS CoV2) infecting humans has emerged in Wuhan, China which caused an unprecedented pandemic involving at least 185 countries infecting 2.5 million people till date. |
| 32562915 | In general, based on existing data published to date, 80.9% of patients infected with the virus develop mild infection; 13.8% severe pneumonia; 4.7% respiratory failure, septic shock or multi-organ failure; 3% of these cases are fatal. |
| 32563019 | In this paper, we have reviewed the relevant knowledge based on up-to-date literature. |
| 32563601 | One thousand six hundred fifty-one of 3,369 patients tested have had SARS-CoV-2-positive results to date. |
| 32563745 | Protective factors included having sufficient medical resources, up-to-date and accurate information, and taking precautionary measures. |
| 32564417 | Some systemic and biologic psoriasis treatments [SBT] have been associated with an increased risk of infection.1 To date, more and more data regarding the risk of COVID-19 infection in patients receiving SBT becomes available.2-5 To enrich these data, we evaluated the frequency of severe COVID-19 infections, defined as hospitalisation or death, in psoriasis patients receiving SBT, especially during the 4 months following SBT initiation. |
| 32565599 | The review focuses on the various approaches adopted till date for developing effective therapeutic strategies including combination of drugs, vaccine therapy, and convalescent plasma therapy to combat this viral outbreak. |
| 32565901 | The Brazilian Gastrointestinal Tumours Group board of directors and members sought up-to-date scientific literature on each tumour type and discussed all recommendations by virtual meetings to provide evidence-based-and sometimes, expert opinion-recommendation statements. |
| 32566128 | During COVID-19 pandemic, allergists have the responsibility of balancing individual patients’ needs with public health issues, and innovative tools, such as telemedicine and digital medicine services, can be helpful to reduce the risk of viral spreading while delivering up-to-date personalized care. |
| 32566234 | Sequences were selected based on the travel history of the individual and the collection date. |
| 32567995 | Till date, no potential medicine/ drug is available to cure the infected persons from SARS-CoV-2. |
| 32568499 | We carry out a review of the little scientific evidence based mainly on the few publications available to date and on the recommendations of the main scientific societies regarding which patients should undergo surgery, when surgery should be performed and how patient visits should be organize. |
| 32569196 | All the above databases will be searched from the available date of inception until the latest issue. |
| 32569422 | The consensus to date is that most infants and children only have mild COVID-19 symptoms and few require intensive care. |
| 32570240 | To date, the clinical characteristics of coronavirus disease 19 (COVID-19)-infected urologic cancer patients are unknown. |
| 32570713 | Little information on the SARS-CoV-2 virus in animals is available to date. […] Whereas no one husbandry animal case has been reported to date, which would have significant implications in food safety, companion animals play a role in COVID-19 epidemiology that opens up new questions. |
| 32570819 | The public relied on online sources, whether through official websites or phone-based applications, to acquire up-to-date health information, provide accurate instructions, and limit misinformation. |
| 32570995 | To date, there has been no definite therapy for COVID-19. |
| 32571224 | To date, there have been few reports of the varying degrees of illness caused by the COVID-19. |
| 32571528 | Our work also stresses the importance of reliable up to date epidemiological data in order to accurately assess the impact of Public Health policies on viral outbreak. |
| 32571980 | Detection of SARS-CoV-2 infections to date has relied heavily on RT-PCR testing. […] Combining excess ILI counts with the date of onset of community transmission in the US, we also show that the early epidemic in the US was unlikely to have been doubling slower than every 4 days. |
| 32572816 | To date May 5 2020, if we carry out a search in pubmed with the keyword “COVID-19”, more than 9000 papers appear. |
| 32573501 | To date, however, we know that COVID 19 affects numerous areas of the body (1,2). |
| 32573538 | To date, in the treatment of COVID-19 in different countries, a little more than 10 drugs are used. |
| 32574109 | Expected final online publication date for the Annual Review of Pharmacology and Toxicology, Volume 61 is January 8, 2021. |
| 32574177 | We first used case reports from Japan, Singapore, and Korea to investigate the date of flights of infected travelers. |
| 32574232 | However, to date, efforts at improving sanitary safety in toilet use have been insufficient. |
| 32574277 | There are, to date, no adequately powered prospective trials addressing this important question. |
| 32574285 | In conclusion, to date, no convincing evidence has been found for vertical transmission of SARS-CoV-2. |
| 32574286 | To date, many cases have been reported in the pediatric age group, most of which were from China. |
| 32574303 | Then, we consider the Lombardy case and calibrate the model with the number of dead individuals to date (May 5, 2020) and constrain the parameters on the basis of values reported in the literature. |
| 32575505 | Nevertheless, to date, the best/optimal method to screen HWs for SARS-CoV-2 infection is still under debate, and data on the prevalence of SARS-CoV-2 infection in HWs are still scarce. |
| 32575763 | Iran has faced one of the worst COVID-19 outbreaks in the world, and no studies to date have examined COVID-19-related stress in the general Iranian population. |
| 32576386 | The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected several millions and killed more than quarter of a million worldwide to date. |
| 32576468 | In aviation after a prolonged period of absence from flying, this deficit in keeping skills and thinking up to date is known as being “out of currency” or “not current”. |
| 32576811 | The number of people infected up to the date of lockdown was also registered. |
| 32578811 | We use a time series analysis of deaths due to COVID-19 referenced to the date of deaths (as opposed to the date in which the test results were obtained). […] The use of a time series of deaths due to COVID-19 referenced to the date of the event allows a better understanding of the effects of the SDS on the progression of the COVID-19 epidemic in São Paulo State, Brazil. |
| 32579306 | Based on reports to date, neurological signs or symptoms appear in 30-50% of hospitalized COVID-19 patients, with higher incidence in those with more severe disease. |
| 32579957 | Up-to-date, a number of mechanisms have been postulated for COVID-19-associated cardiovascular damage including SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) activation, cytokine storm, hypoxemia, stress and cardiotoxicity of antiviral drugs. |
| 32580535 | Compared to scenario I, it was found that in scenario III, the cumulative number of patients would increase by 107 and the date of occurrence of the last patient would be delayed by 92 days. |
| 32581810 | To date, there are no specific therapeutic strategies for treatment of COVID-19. |
| 32582324 | To date, April 25, 2020, more than 2.4 million humans are infected and more than a hundred thousand deaths have been reported from more than 200 countries from COVID-19. |
| 32582615 | The final date of follow-up was March 6th, 2020. |
| 32582739 | We also estimate the fraction of the population that would be infected by the beginning of May, at the official date at which the lockdown should be relaxed. |
| 32583671 | To date, no cases have been reported on the effects of COVID-19 in laryngectomees. |
| 32584779 | To date, there is limited evidence on how the infodemic may have the potential to influence psychobehavioural responses to the crisis. |
| 32584795 | To date, data to assess the prevalence and severity of COVID-19 among pregnant U.S. women and determine whether signs and symptoms differ among pregnant and nonpregnant women are limited. |
| 32586214 | The evidence to date supports the concept that the thrombotic manifestations of severe COVID-19 is due to the ability of SARS-CoV-2 to invade endo¬thelial cells via angiotensin-converting enzyme 2 (ACE2), which is expressed on the endothelial cell surface. |
| 32586323 | This was a retrospective cohort study from electronic case records of the first 450 patients admitted to our hospital with PCR-confirmed COVID-19, 77% of the total inpatient caseload to date. |
| 32586363 | Registration date is April 14, 2020. |
| 32586399 | Triiodothyronine for the Treatment of Critically Ill Patients With COVID-19 Infection (Thy-Support), ClinicalTrials.gov Identifier: NCT04348513, date of trial registration: April 16, 2020, EudraCT Identifier: 2020-001623-13, date of trial registration: April 22, 2020 FULL PROTOCOL: The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). |
| 32587651 | No vaccine has been developed against the 2019-nCoV virus to date. |
| 32588589 | Case studies to-date indicate that this infection causes a mild illness (i.e. pneumonia or mild pneumonia) in approximately 80% of cases, and most cases recove; 14% have a more severe illness, 6% experience a critical illness. […] This article contains up-to-date information as at 04/04/2020. |
| 32589600 | To date, many biomarkers reflecting the main pathophysiological characteristics of the disease have been identified and associated with the risk of developing severe disease. |
| 32590725 | In the global coronavirus disease 2019 (COVID-19) pandemic, to date, delivery of critically ill pregnant patients has predominantly been by cesarean. |
| 32591166 | Although the number of studies to date is limited, LUS findings have demonstrated high diagnostic sensitivity and accuracy, comparable with those of chest computed tomography scans. |
| 32591466 | We summarize the immunogenicity of leading vaccine candidates tested to date in animals and humans, and discuss the outcome and interpretation of virus-challenge experiments in animals. |
| 32591665 | Publications up until the date of the literature search, 19th March 2020, were used. |
| 32591667 | Besides the clinical guidelines presented within the study, it also encourages further up-to-date and evidence-based management guidelines for patients with COVID-19. |
| 32591712 | This paper describes its evolution to date and the challenges encountered along the way. |
| 32593065 | To date, we have no French data about the psychiatric consequences of the Covid-19 pandemic and the confinement. |
| 32593339 | To date, few data on paediatric COVID-19 have been published, and most reports originate from China. |
| 32593341 | Physicians were encouraged to report cases prospectively and we permitted recent cases to be notified retrospectively when assigned a confirmed date of admission or initial clinical assessment, allowing identification of cases that occurred before notification portals were available. |
| 32593519 | Although scientists and researchers have been racing to develop specific therapeutic agents or vaccines against SARS-CoV-2 since the identification of the agent, either a drug or a vaccine has not been approved to treat or to prevent COVID-19 up to date. |
| 32593564 | We inquired about their COVID-19-related experiences and perspectives, documented opportunities for transmission, and assessed COVID-19’s perceived impacts to date. |
| 32594928 | The date of infection and infector-infectee pairs were inferred from the history of travel in Wuhan or exposed to confirmed cases. |
| 32595070 | To date, injecting drug use has been of primary concern in relation to harm reduction initiatives. |
| 32595085 | With a necessary cautionary note that the evidence around the links between Covid-19 and cardiovascular disease is accruing at a fast pace, to date we can conclude that: (a) the greater susceptibility of individuals with underlying cardiovascular conditions to develop more severe Covid-19 with higher mortality rate is likely to be confounded, in part, by age and the type of co-morbidities. |
| 32599060 | This last decade, the literature on remote home-based CR programs has been increasing, but to date only clinical research experiences have been implemented. |
| 32599100 | This study used publicly available data to examine gender, age, source of infection, date returned from Hubei, date of disease onset, date of first medical visit, date of final diagnosis, and date of recovery of COVID-19 cases. |
| 32599811 | We achieved the aim by (1) sampling Weibo users (geo-location = Wuhan, China) and Twitter users (geo-location = Lombardy, Italy); (2) fetching all the users’ published posts two weeks before and after the lockdown in each region (e.g., the lockdown date of Wuhan was 23 January 2020); (3) extracting the psycholinguistic features of these posts using the Simplified Chinese and Italian version of Language Inquiry and Word Count (LIWC) dictionary; and (4) conducting Wilcoxon tests to examine the changes in the psycholinguistic characteristics of the posts before and after the lockdown in Wuhan and Lombardy, respectively. |
| 32600881 | General surgery chief residents were most concerned about the potential delay in the date of board examinations, followed by not feeling adequately prepared for the board examinations and a possible delay in the graduation date. |
| 32601708 | The termination date of follow-up was 19 February 2020. |
| 32603253 | To date, physical distancing and good personal hygiene have been the only effective measures to limit spread. |
| 32603900 | Members of the Telemedicine Work Group in the American Academy of Allergy, Asthma & Immunology (AAAAI) completed a telemedicine literature review of online and Pub Med resources through May 9, 2020, to detail Pre-COVID-19 telemedicine knowledge and outline up-to-date telemedicine material. |
| 32604138 | In the largest cohort to date of PLWH and confirmed COVID-19, almost all had a comorbidity associated with severe disease, highlighting the importance of non-HIV risk factors in this population. |
| 32605192 | Analyzing the diagnostic methods, to date, virus nucleic acid RT-PCR represents the standard method used to ascertain the COVID-19 infection in living subjects and corpses, even if this technique has several criticisms: mainly, the staff should be highly specialized, working in high-throughput settings, able to handle high workloads and aware of health risks and the importance of the results. |
| 32605363 | To date, many serology LFAs have been developed, though none meet the performance requirements necessary for diagnostic use cases, primarily due to the relatively long delay between infection and seroconversion. […] To date, only a very small number of antigen-detecting LFAs have been developed. |
| 32605549 | Scientific studies to date have focused primarily on describing the clinical course of patients, identifying treatment options and developing vaccines. |
| 32606050 | To date, there are no effective antiviral medications for COVID-19. |
| 32607332 | To date, a limited number of studies have concentrated on the epidemiological and clinical characteristics of COVID-19 patients with different genders, clinical classification, and with or without basic diseases. |
| 32607499 | To date, there is no specific vaccine or treatment proven effective against this viral disease. |
| 32607737 | The COVID-19 pandemia due to the SARS-CoV-2 coronavirus, in its first 4 months since its outbreak, has to date reached more than 200 countries worldwide with more than 2 million confirmed cases (probably a much higher number of infected), and almost 200,000 deaths. |
| 32608335 | The onset date of the earliest COVID-19 case in this study was 25 January 2020. |
| 32609079 | To date, 110,000+ people in the United States have died from the COVID-19 pandemic. |
| 32609085 | This review represents the most up to date information published in the literature that is a must-know to every orthopedic surgeon. |
| 32609825 | Epidemiological parameters for COVID-19 were validated on a limited date range; where substantial uncertainties remained, multiple parameters were tested. |
| 32609839 | Most importantly, to date, no study, including this one, supports the view that smoking acts as a treatment intervention or prophylaxis to reduce the impact or ameliorate the negative health impacts of COVID-19. |
| 32610808 | The experience in the United Kingdom and Canada to date has not seen much uptake of health economics methods. |
| 32610873 | The indoor admitted patient’s information inclusive of demographic profile (age, sex, nationality, residence), date of confirmation for positive COVID-19 case, travel/ exposure history, date of recovery/ death, clinical features, co morbidities and treatment plan was recorded. […] 60.27% of patient population with underlying co morbid conditions were more prone to develop symptomatology complex as compared to that observed in patients with no co morbidity (18.42%). 116 patients had recovered with effective treatment till the date of data analysis. […] Time of recovery was counted from the date of positive report to 1st negative report of oropharyngeal sample by RT-PCR for COVID-19 with an average recovery time of 8.15 days. |
| 32610879 | This prompted physicians from across the world to use them in the present SARS-CoV- 2 pandemic that is currently sweeping the globe, with 5 million people already infected to date. |
| 32611457 | To date, there is not much information published addressing the cardiac workup and monitoring of children with COVID-19. |
| 32611687 | The present review summarizes up-to-date evidence addressing the frequently discussed clinical controversies regarding the use of immune checkpoint inhibitors (ICIs) in cancer patients with viral infections, including AIDS, hepatitis B and C, progressive multifocal leukoencephalopathy, influenza, and COVID-19. |
| 32611746 | No restriction regarding the publication date, setting or languages will be considered. |
| 32611914 | We described cases by time (epidemic curve by date of specimen collection; seven-day moving average), place (area map) and person (attack rate by age, sex and contact status), and trends were represented along with public health measures and events. |
| 32614777 | The variables analyzed were name, platform, country, language, category, cost, update date, size, version, number of downloads, developer, and purpose. […] The mean time between the date of the analysis and the date of the last update was 11.1 days (SD 11.0). |
| 32614810 | Respondents were contacted 14-21 days after SARS-CoV-2 testing and asked about their demographic characteristics, underlying chronic conditions, symptoms experienced on the date of testing, and potential exposures to SARS-CoV-2 during the 2 weeks before illness onset (or the date of testing among those who did not report symptoms at the time of testing). |
| 32615862 | To date, a large number of clinical trials addressing various aspects of COVID19 have been registered in the Chinese Clinical Trial Registry (ChiCTR), including more than 200 interventional studies. |
| 32615871 | To the best of our knowledge, no new infectious case of COVID-19 resulting from endoscopic procedures has been reported in China to date. |
| 32616067 | Time to diagnosis of positive COVID-19 disease (defined by record of date of symptoms onset and confirmed by laboratory test) RANDOMISATION: Participants will be randomised to either hydroxychloroquine dosed daily with weekly placebo, HCQ dosed weekly with daily placebo, or placebo dosed daily and weekly. […] V 1.0, 7th April 2020 EU Clinical Trials Register EudraCT Number: 2020-001331-26 Date of registration: 14th April 2020 Trial registered before first participant enrolment. […] The recruitment end date cannot yet be accurately predicted. |
| 32617010 | Not enough systematic reviews on predictors of critical illness and mortality in COVID 19 have been published to date. |
| 32617050 | There have been approximately 7734185 reported cases, and 412369 reported deaths to date (09/June/2020). |
| 32617169 | To date, there are no especial therapeutic agents for COVID-19 infections. |
| 32617313 | Evidence generated to-date on the virulence and pathogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) suggests that COVID-19 may be considered a perfect storm, caused by a nature’s virtually perfect biological weapon. |
| 32617365 | The World Health Organization has declared COVID-19 a global pandemic, with a death toll of over 300,000 to date. |
| 32619756 | To date, the most commonly used method for identifying and confirming the virus is the laboratory-based reverse transcription-polymerase chain reaction (RT-PCR) test. |
| 32621281 | Recently, concern arose on unrecognized infections before this date. |
| 32622375 | Encephalitis has been described in eight patients to date, and Guillain-Barré syndrome in 19 patients. |
| 32623176 | Till date no medication or vaccine is available to cope with the COVID-19 infection and infection rate is increasing drastically across the globe. |
| 32624494 | To date, there has been no clear guideline endorsement of ward-based non-invasive pressure support (NIPS) for severely hypoxic patients who are deemed unlikely to benefit from invasive ventilation. |
| 32624560 | Socio-demographic and clinical data, aspects of the event-exposure (date, place, length and distance of exposure, use of PPE) and details of the contact person were collected. |
| 32627172 | The commonly used contact-tracing based estimation of incubation distribution is highly influenced by the individuals’ judgment on the possible date of exposure, and might lead to significant errors. |
| 32627963 | To date, the impact, timeline and duration of COVID-19 pandemic remains unknown and more than ever it is necessary to provide safe pathways for cancer patients. |
| 32629147 | Patients with a positive COVID-19 diagnosis were given a questionnaire consisting of general questions (age, sex, date of symptoms, smoking history, concomitant diseases), questions about the most obvious symptom at presentation (one option only), the severity and frequency of symptoms (general and ENT), and STL (recovery time and degree of recovery). |
| 32630746 | Up to date, neither an effective vaccine nor SARS-CoV-2 specific antiviral agents have been approved, but significant advances were enlisted in this direction by investigating repurposed approved drugs (ongoing clinical trials) or developing innovative antiviral drugs (preclinical and clinical studies). |
| 32631426 | April 1, 2020 would be a reasonable date to lift quarantine in Hubei and Wuhan. |
| 32631442 | The retrieval inception date was February 9, 2020. |
| 32632766 | Nevertheless, up to date, no drugs have been confirmed as a definitive treatment for COVID-19. |
| 32632960 | To date, no vaccines or effective therapeutics have been discovered yet that may successfully treat COVID-19 patients or contain the transmission of the virus. |
| 32633720 | By contrasting Electronic Health Record (EHR)-derived symptoms of COVID-19-positive (COVIDpos ; n = 2,317) versus COVID-19-negative (COVIDneg ; n = 74,850) patients for the week preceding the PCR testing date, we identify anosmia/dysgeusia (27.1-fold), fever/chills (2.6-fold), respiratory difficulty (2.2-fold), cough (2.2-fold), myalgia/arthralgia (2-fold), and diarrhea (1.4-fold) as significantly amplified in COVIDpos over COVIDneg patients. |
| 32633997 | To date, there is no recommended medical treatment, and supportive measures are a crucial part of management. |
| 32634106 | Descriptive data will include patient demographics, the radius of care, the time between the date of injury and initial visit, the average number of follow-up visits, and days until medically cleared for return-to-learn and return-to-play. |
| 32634536 | In these patients, the mean from the date of their first detectable result to attaining an undetectable result was 14.89 days. |
| 32637738 | Informed consent and Institutional Review Board approval was obtained prior to this study (196/2020BO2; Date of approval: 03/26/2020; Ethics Committee of the University of Tuebingen). |
| 32638221 | To date, many studies have discussed that the rationale behind its transmission potential is that viral RNA has unexpectedly been detected in multiple bodily fluids, with some samples having remained positive for extended periods of time. |
| 32638896 | Classical definition of myocarditis, supported by endomyocardial biopsy of inflammatory infiltrate, is rare; it has been observed in only one case report to date, and the virus has not been identified inside cardiomyocytes.Thus, the phenomenon that has been documented is acute myocardial injury, making it necessary to rule our obstructive coronary disease based on increased markers of myocardial necrosis, whether or not they are associated with ventricular dysfunction, likely associated with cytokine storms and other factors that may synergistically promote myocardial injury, such as sympathetic hyperactivation, hypoxemia, arterial hypotension, and microvascular thrombotic phenomena.Systemic inflammatory and myocardial phenomena following viral infection have been well documented, and they may progress to cardiac remodeling and myocardial dysfunction. |
| 32639216 | To date and to our knowledge, a small amount of reports describing a surgical department’s response to this unprecedented pandemic have been published, but a well-documented account from within the United Kingdom (UK) has not yet been reported in the literature. |
| 32639466 | We observed a greater proportion of hospitalized children requiring mechanical ventilation than has been reported to date. |
| 32639598 | This impact in the specific setting of transplantation and immunosuppression has been poorly explored to date. |
| 32640723 | The world is currently suffering from a pandemic which has claimed the lives of over 230,000 people to date. |
| 32641154 | TACTIC-R Protocol version number 2.0 date May 20, 2020, recruitment began May 7, 2020 and the end trial will be the date 18 months after the last patient’s last visit. […] The recruitment end date cannot yet be accurately predicted. |
| 32641343 | To date, symptomatic supportive care has been the most common treatment. |
| 32642842 | To date, no vaccines are available nor any specific treatment. |
| 32642929 | To date, however, training opportunities in this field have been limited, and residents may not be adequately prepared to provide high-quality telemedicine care. |
| 32643136 | To date, it is essential for all Specialists, clinicians and surgeons, to direct attention towards the study of this virus, to better clarify the spectrum of its neurological manifestations. |
| 32644140 | Patients were divided into 5 groups based on the date of their clinical presentation in relation to the COVID-19 pandemic. |
| 32644275 | To date, data is limited for medications that facilitate clinical improvement of COVID-19 infections. |
| 32645207 | To date, reports from China, United States and Europe did not reveal an higher risk of infection, either for rheumatoid arthritis, juvenile idiopathic arthritis nor for lupus erythematosus. |
| 32645276 | To date, the world has paid a high toll in this pandemic in terms of human lives lost, economic repercussions and increased poverty. |
| 32645974 | In an up-to-date format, we shed light on HCQ’s anecdotal function in stalling SARS-CoV-2 replication and immunomodulatory activities. |
| 32646502 | The protocol with code TAC-COVID-19, version 2.0 on date: April 16, 2020 is approved by the Spanish Drug Agency (AEMPS) and the local Ethics Committee. |
| 32647526 | To date, there are 12 case studies reporting 47 cases of CVD in COVID-19. |
| 32647807 | To date, preliminary evidence from case series is favorable as significant clinical, biochemical improvement and hospital discharge have been reported. |
| 32648093 | The final date of follow-up was Mar 31, 2020. |
| 32648218 | The study calculated that if we increase five times our testing capacity from the current date, the total registered cases will be reached to 137,370 and death tolls will increase up to 3090. |
| 32648546 | From the largest U.S. serosurvey to date, we estimated >2 million adult New York residents were infected through late March, with substantial disparities, although cumulative incidence remained less than herd immunity thresholds. |
| 32648592 | To date, there are no clear scientific data that preclude the use of non-steroidal anti-inflammatory drugs in the general population who may acquire COVID-19 or in those acutely infected with the virus. |
| 32648973 | To date, however, there is a very limited understanding of the extent and management of COVID-19-related conditions outside of the pulmonary system. |
| 32649214 | Volumes were evaluated by result date (3/16/2020 - 5/6/2020) and the average of received to verified turn-around-time (TAT) was calculated and compared for in-house and send-out testing, and different in-house testing methodologies. |
| 32649222 | Several biomarkers have been proposed to predict COVID-19 severity, but no definite interpretative criteria have been established to date for stratifying risk. |
| 32649399 | To date, over 180 PICUs have responded detailing 530 PICU admissions requiring over 3,467 days of PICU care with 30 deaths. |
| 32649566 | At the end of December, 2019, a new virus was named severe acute respiratory syndrome coronavirus 2 appeared in Wuhan, China, and the disease caused is called as coronavirus disease 2019 (COVID-19) by World Health Organization, which to date having infected more than 3,588,773 people worldwide, as well as causing 247,503 deaths. |
| 32650818 | Protocol version number: V3, 19.05.2020 Recruitment not yet started but is anticipated to begin by June 2020 and be complete by December 2020 TRIAL REGISTRATION: ClinicalTrials.gov: NCT04351516 , date: 17 April 2020 EudraCT: 2020-001482-37, date: 30 March 2020 FULL PROTOCOL: The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). |
| 32653015 | To date, no specific treatment has convincingly demonstrated its efficacy. |
| 32653432 | Given the heterogeneous methods used in studies to date, we are unable to draw conclusions on the most efficacious and safe intervention for decontaminating surgical masks. |
| 32653452 | To date, no effective therapeutic is available to fight its associated disease, COVID-19. |
| 32653819 | To date, it is often considered obsolete giving the inadequacy to provide samples of a quality appropriate to the sophisticated diagnostic techniques available today. |
| 32653906 | No cases involving young patients have been presented to date. |
| 32654024 | While it is being recommended to carry out only the emergent procedures and to postpone the non-urgent ones to a later date, this article is meant to provide an insight into triage of the ENT procedures and the various precautions to be taken into account by the ENT surgeons while carrying out a procedure during the COVID-19 pandemic. |
| 32654361 | To date, despite the slow reopening, the government has decided to maintain school closures for the entire academic year, leaving the future of young people in uncertainty. |
| 32656017 | The output of the model is nearly instantaneous, producing an estimate of the census and the number of ventilators required in one, three, and seven days following the date on which the simulation is run. |
| 32657527 | We highlight challenges of outpatient and inpatient HIV care in the setting of the COVID-19 pandemic and present the largest detailed case series to date from the United States on HIV/SARS-CoV-2 coinfection, adding to limited global reports. |
| 32657710 | Evidence to date suggests that COVID-19 is efficiently passed from infected individuals via large droplets and hard-surface fomites. |
| 32658096 | To date, although neonatal infections with severe acute respiratory syndrome coronovirus 2 (SARS-CoV-2) have been described, none of these have been proven to be the result of vertical transmission of SARS-CoV-2. |
| 32658132 | To date, there are no centralized or compiled international COVID-19 guidelines for oculoplastic surgeons. |
| 32658735 | To date, no approved treatment regimen or vaccine is available to effectively attenuate or prevent the infection. |
| 32658757 | Up to this date, there is no scientific evidence that proves that a COVID-19 corpse is still infectious. |
| 32658841 | Convalescent plasma is the only antibody-based therapy available for COVID-19 patients to date. |
| 32658858 | We examined the trends in the percent increase in daily new cases from 7 days before to 30 days after the dates on which containment measures went into effect by continent, World Bank income classification, type of containment measures, effective date of containment measures, and number of confirmed cases on the effective date of the containment measures. |
| 32658879 | Lockdown and self-isolation are to date the only solution to limit the spread of recent outbreak of coronavirus disease (CoViD-19), highlighting the great advantage of home dialysis in a patient otherwise forced to travel from / to the dialysis center to receive this “life-saving” treatment. […] Peritoneal dialysis (PD) represents a type of home dialysis therapy not yet adequately implemented to date, in spite of safe and simple practice, as well as similar dialytic efficiency vs in-center hemodialysis. |
| 32659292 | To date, no vaccines or specific antiviral drugs have been approved for the treatment of this disease in clinic. |
| 32660220 | To estimate time-variant reproductive number (Rt) of coronavirus disease 19 based on either number of daily confirmed cases or their onset date to monitor effectiveness of quarantine policies. […] Using number of daily confirmed cases from January 23, 2020 to March 22, 2020 and their symptom onset date from the official website of the Seoul Metropolitan Government and the district office, we calculated Rt using program R’s package “EpiEstim”. […] For asymptomatic cases, their symptom onset date was considered as -2, -1, 0, +1, and +2 days of confirmed date. […] When we changed assumed onset date for asymptotic cases (-2 days to +2 days of the confirmed date), the results were comparable. |
| 32660611 | query=ALXN1210-COV-305 , Start date: 07 May 2020 FULL PROTOCOL: The full redacted protocol is attached as an additional file, accessible from the Trials website (Additional file 1). |
| 32661780 | The Italian College of Breast Radiologists by the Italian Society of Medical Radiology (SIRM) provides recommendations for breast care provision and procedural prioritization during COVID-19 pandemic, being aware that medical decisions must be currently taken balancing patient’s individual and community safety: (1) patients having a scheduled or to-be-scheduled appointment for in-depth diagnostic breast imaging or needle biopsy should confirm the appointment or obtain a new one; (2) patients who have suspicious symptoms of breast cancer (in particular: new onset palpable nodule; skin or nipple retraction; orange peel skin; unilateral secretion from the nipple) should request non-deferrable tests at radiology services; (3) asymptomatic women performing annual mammographic follow-up after breast cancer treatment should preferably schedule the appointment within 1 year and 3 months from the previous check, compatibly with the local organizational conditions; (4) asymptomatic women who have not responded to the invitation for screening mammography after the onset of the pandemic or have been informed of the suspension of the screening activity should schedule the check preferably within 3 months from the date of the not performed check, compatibly with local organizational conditions. |
| 32661937 | However, to date, mortality rate among children is low as they mostly suffer from a mild disease. |
| 32662062 | We have studied up-to-date knowledge about the clinical feature of the Novel coronavirus pandemic worth consideration by the urologist. |
| 32662421 | To date, no consistent evidence for the vertical transmission of SARS-CoV-2 exists. |
| 32662525 | As of the final follow-up date of this study, 240 (83.0%) patients were discharged from the hospital and 49 (17.0%) patients died. |
| 32662615 | Up to date few studies have actually assessed the impact of COVID-19 on the postoperative morbidity and mortality following emergency gastrointestinal surgery. |
| 32662690 | The coronavirus disease 2019 (COVID-19) pandemic has affected almost 2.5 million people worldwide with almost 170,000 deaths reported to date. |
| 32662757 | To date, 23 data collection partners are involved and the first data imports have been performed successfully. |
| 32662814 | To date, the number of COVID-19 patients worldwide has crossed over six million with over three hundred and seventy thousand deaths (according to the data from World Health Organization; updated on 2 June 2020). |
| 32663708 | To the best of our knowledge, till date only one compound has been identified and tested in-vivo as a potent inhibitor of Mpro protein, addressed as N3 (PubChem Compound CID: 6323191) and is known to bind irreversibly to Mpro suppressing its activity. |
| 32664113 | The study will provide up-to-date evidence of the effectiveness and safety of A&M for patients with COVID-19. |
| 32664908 | Pertinence has various dimensions, including whether the guidance applies to this professional, this patient and/or this setting, whether it is up-to-date, and whether the guidance addresses the situation the professional is facing. |
| 32665039 | Recruitment is ongoing - started April 20, 2020 and anticipated end date is July 30, 2021 TRIAL REGISTRATION: ISRCTN.com Identifier: ISRCTN14326006, registered April 14, 2020. |
| 32665090 | To date, there is no evidence of a higher incidence of COVID in patients with autoimmune rheumatic diseases and we support the approach of maintaining chronic rheumatological treatments. |
| 32665091 | The first week of this date range and the 10 weeks prior were used to derive the normal practice expected volume. |
| 32665331 | Similarly, we show that the apparent oscillation in mortality in the U.S. data are mostly an artifact of reporting, which disappears in data sets that record death by episode date, such as the NYC and LA data sets. |
| 32665352 | The PubMed, Embase, Web of Science, the Cochrane Central Register of Controlled Trials, Chinese Biomedical Literature Database, China National Knowledge Infrastructure, Wanfang Data and Viper information databases will be searched from inception time to date without restricting research types to find relevant studies. |
| 32666513 | No study published to date has analyzed the characteristics of headache in these patients. |
| 32666588 | To date, available data are heterogeneous and scarce and mortality in LT recipients seems to be higher compared to normal population, but whether this is caused by altered immunological status, immunosuppression (IS), or underlying comorbidities has not yet been fully clarified. […] To date, 244 LT recipients have been reported as COVID-19-positive. |
| 32666887 | To date, no definitive treatments to the pandemic have been promoted. |
| 32666912 | The global impact on the clinical practice of manual therapy and education has to date not been explored. a questionnaire survey methodology was used. |
| 32668041 | The role of extracorporeal membrane oxygenation (ECMO) remains unknown, with the few publications to date lacking detailed patient information or management algorithms all while reporting excessive mortality. |
| 32668803 | SARS-CoV-2 infection/COVID-19 provides numerous therapeutic targets, each of them promising, but not leading to the success of therapy to date. |
| 32669221 | The definition and diagnostic/management criteria of sepsis have been modified several times but the mortality rate has not been improved until date. |
| 32670391 | Up to date, facts and figures of the total the confirmed cases, daily confirmed cases, total deaths, and daily deaths that have been reported in the Asian countries are provided. |
| 32670517 | To date, no definite link has been irrefutably found between a single infection and KD. |
| 32671688 | To date, the USA, Italy, Spain, France, Russia, and the UK have been hit the hardest by the virus. |
| 32673296 | Symptom data were analyzed by age group, sex, hospitalization status, and symptom onset date relative to expansion of testing guidelines on March 8, 2020 (3). |
| 32674646 | Data about timing of symptom onset and death (pregnancy or postpartum), gestational age, mode of birth, maternal age, comorbidities and/or risk factors, date of death, and place of death were retrieved when available. |
| 32674969 | However, to this date, there has been no clear evidence to suggest either way. |
| 32675033 | To date, however, no literature has focused on the clinical symptoms of emergency surgery patients with COVID-19 pneumonia. […] For this report, the final date of follow-up was February 5, 2020. |
| 32676039 | Up to date (2020 May 6) in Italy we had more than 28,000 deaths, while there were more than 205.000 infected. |
| 32676080 | As a result, there is no specific treatment available to date for CRS, and it is managed only symptomatically to support the deteriorating organ functions and maintain the blood pressure. |
| 32676542 | We searched the available literature to-date, and present the pathophysiology underlying increased morbidity and mortality of SARS-CoV-2 infection in the lungs, heart and kidneys in a highly illustrated presentation that is easy-to-understand for the clinician, researcher, and student alike. |
| 32676882 | To date, it’s not fully clear how COVID-19 may affect patients with hereditary bleeding disorders. |
| 32678017 | No effective treatment has been discovered to date. |
| 32678672 | Training efficiency was measuring by the days between the date of product shipment and the date of the first and final trainings. |
| 32678949 | To date, however, pregnant women do not appear to have a substantially increased risk of thrombotic complications related to COVID-19. |
| 32679155 | To date there are few reports of ST-segment elevation myocardial infarction (STEMI) caused by type 1 myocardial infarction in patients with COVID-19. |
| 32679173 | Unfortunately, no antiviral medications have been discovered to date as treatments for any of these diseases. […] By contrast, the HIV/AIDS pandemic has garnered consistent research investment since it began and resulted in drugs being developed within 7 years of its start date, with many more to follow. |
| 32679185 | To date, some aspects remain to be investigate about the pathophysiology of this viral infection. |
| 32679206 | The guiding principles for restarting elective surgeries in a safe and acceptable manner include up-to-date disease awareness, projection and judicious management of equipment and facilities, effective human resource management, a fair and transparent system to prioritize cases, optimization of peri-operative workflows and continuous data gathering and clinical governance. |
| 32680478 | To date, the psychological impact of COVID-19 epidemic among family members of health care workers (HCWs) in China has been neglected. |
| 32680658 | Based on the official data available on the date of this work, and through the models described, we estimate a total of around 240.000 infected and 25.000 deaths at the end of the epidemic. |
| 32680910 | To date, pathologic analyses have been limited to patient reports and autopsy series. |
| 32681089 | The World Health Organization has stated “To date there has been no information nor evidence to suggest that the new coronavirus could be transmitted by mosquitoes”. |
| 32681845 | To date, coagulopathy has been found as a prominent feature of COVID-19 and severe coagulation dysfunction may be associated with poor prognosis. |
| 32681968 | Fever and cough are the most common symptoms of COVID-19 infection in the literature published to date. |
| 32682491 | To date, documentation of the histopathological features in fatal cases of the disease caused by SARS-CoV-2 (COVID-19) has been scarce due to sparse autopsy performance and incomplete organ sampling. |
| 32683373 | To date, oncology and surgery groups have only given instructions for addressing phases 1 and 2. |
| 32683801 | Although no randomized clinical trials have been published to date, it is interesting to explore potential modalities for treating COVID-19 in children, based on review articles, case reports, and recent guidelines. |
| 32684674 | To this date, there are no universal guidelines for musculoskeletal (MSK) care in the face of the coronavirus pandemic. |
| 32687630 | To date, these medications are not approved for the treatment of viral infections, and there are no well-controlled, prospective, randomized clinical studies or evidence to support their use in patients with coronavirus disease 2019 (COVID-19). […] In addition, this work presents data describing the proposed mechanisms of action against the severe acute respiratory distress syndrome coronavirus-2 and summarizes clinical efficacy to date. |
| 32687823 | Current survival is 96.3%, with only 1 death to date in more than 350 days of total ECMO support. |
| 32687997 | Water bodies receiving raw sewage may pose risk of infection but this has not been investigated to date. |
| 32689586 | Treatment was changed to enoxaparin and no thrombotic events were encountered to date. |
| 32689925 | We collected information on the date of publication, first author’s country, the title of the article, study design, study population, intervention and outcome, and key findings, and divided all research articles into two domains: physical and mental health impact. |
| 32690074 | EUDRACT number: 2020-001667-85; date of trial registration: 15 May 2020 Protocol registered on ClinicalTrial.gov, registration number: NCT04361474 ; date of trial registration: 24 April 2020. |
| 32690463 | The aim of this study is to systematically review the data available to date regarding the potential risk posed to theatre staff by laparoscopy. […] The data and analysis reported in this study reflect the most up-to-date evidence available for the surgeon to assess risk towards healthcare staff. |
| 32691024 | In this review we summarize the most up to date literature around the association between COVID-19 and myocarditis and provide clinicians a practical framework about the clinical manifestations, diagnostic tools, and treatment options currently available. |
| 32691236 | To date, only smaller cohort studies or single cases have reported cerebrovascular events, seizures, meningoencephalitis, and immune-mediated neurological diseases, not suitable for quantitative analysis. |
| 32692365 | The number of infections in each site was estimated by extrapolating seroprevalence to site populations; estimated infections were compared with the number of reported coronavirus disease 2019 (COVID-19) cases as of last specimen collection date. |
| 32692408 | To date, some limited studies have been published on placentas from SARS-CoV-2-positive women. |
| 32692580 | To date, only dexamethasone and remdesivir have been shown to be effective, but several other promising candidates are in trials. |
| 32692649 | To date, there have been no cases of in-hospital spread to other patients or to professionals in this department. |
| 32693023 | To date, there is not any vaccine or specific antiviral medicine that can prevent or treat this virus. |
| 32693652 | To date, clinical evidence suggests lack of benefit from HCQ use for the treatment of hospitalized patients with COVID-19. |
| 32694143 | To date, limited genetic changes in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome have been described. |
| 32694480 | To date, there has not been literature discussing the process of resuming CFOP mission trips. |
| 32695123 | To date, there has been no mention of this dual connection between GSK-3 and SARs CoV2 in the literature. |
| 32696735 | To date, there have been no detailed reports of patients developing persistent psychotic symptoms following Coronavirus disease 2019 (COVID-19) infection. |
| 32696830 | COVID-19 in pregnant women may not be associated with the occurrence of preterm deliveries or the birth weight of the newborn children, however the evidence to date is very uncertain. |
| 32698862 | A systematic literature review of six databases (PubMed, Scopus, The Cochrane Central Register of Controlled Trials [CENTRAL], Science Direct, Web of Science and Google scholar) was carried out without any restrictions on date of publication to identify the reliability of saliva as a diagnostic specimen for detection of SARS-CoV-2 in suspected patients. |
| 32699006 | Long-term care (LTC) homes have been the epicentre of the coronavirus disease 2019 (COVID-19) pandemic in Canada to date. |
| 32699423 | To date, most studies have been conducted among inpatients with severe COVID-19. |
| 32699691 | Veno-venous extracorporeal membrane oxygenation (VV-ECMO) has been used in some centers, but its role in the setting of COVID-19 infection is still unclear to date. |
| 32703064 | To date, countries have relied on the prevention of the disease through isolation, quarantine, and clinical care of affected individuals. |
| 32703069 | Rapid progress and advances have been made to date in the development of COVID-19 vaccines. |
| 32703089 | To, date no clear indications on how to treat patients with cancer with COVID-19 infection are available. |
| 32705976 | To date, only two treatments, remdesivir and dexamethasone, have demonstrated clinical efficacy through randomized controlled trials (RCTs) in seriously ill patients. |
| 32706095 | The information on daily temperature and humidity was obtained from world climate web “Time and Date”. […] The daily basis, mean temperature and humidity were recorded from the date of appearance of first case of COVID-19 in the region, Jan 29, 2020 to May 15, 2020. |
| 32706371 | The final date of follow-up was May 16, 2020. |
| 32707965 | To date, 38 cases have been reported, with other cases most likely undiagnosed mainly due to a lack of clinical awareness and diagnostic screening. |
| 32708840 | After its arrival in South America in February 2020, the virus has expanded throughout the region, infecting over 900,000 individuals with approximately 41,000 reported deaths to date. |
| 32708858 | To date, most evidence has come from renal transplantation, with about 45 patients reported thus far, and the current data from the ERA-EDTA (ERACODA) registry for transplanted patients and patients on Renal Replacement Therapy (RRT); as for those with glomerular diseases, data are lacking. |
| 32708953 | This short article intends to give an up-to-date glimpse of the pandemic from air quality and climate perspectives and calls for a follow-up discussion. |
| 32710056 | Liverpool University Dental Hospital (LUDH) responded by commencing an emergency dental service on the same date. |
| 32711003 | However, to date, there are no comprehensive studies aiming to explain the exact relationship between diabetes and COVID-19. |
| 32713282 | This broad spectrum of COVID-19 influence on kidney patients and kidney functions obviously necessitate an up to date management policy for nephrological care. |
| 32713385 | We analyzed biosecurity and disinfection standards at the dental office and dental health personnel to date, and their adaptation to the needs and way of working of each. |
| 32713784 | To date, no randomized trials have been published. |
| 32713821 | Very few cases of lung transplant patients affected by coronavirus disease 2019 (COVID-19) have been reported to date. |
| 32715315 | To date, Virus-CKB archived 65 antiviral drugs in the market, 107 viral-related targets with 189 available 3D crystal or cryo-EM structures and 2698 chemical agents reported for these target proteins. |
| 32715498 | However, to date, the quality of the evidence has not been systematically assessed. |
| 32715512 | To date, inpatient facilities for eating disorders (both medical stabilization units and higher level of care facilities) have not needed to consider how to translate services to electronic platforms, given that most of these programs have in-person staff. |
| 32716647 | We used the TriNetX platform to analyze 20 health care institutions that have relevant, up-to-date encounter data. |
| 32716828 | Date of EVT and symptom onset-to-groin puncture time were collected. |
| 32716836 | Analysis of the available literature to date suggests that, in addition to older age, patients with underlying co-morbidities including hypertension, diabetes, heart disease are at higher risk for severe disease with increased mortality. |
| 32716900 | We collected data on the patients’ date of MDPOA completion, use of advance care planning messaging, age, sex, and geographic location during the early phase of the COVID-19 pandemic (December 29, 2019, to May 30, 2020). |
| 32717056 | There have been limited published studies to date documenting the performance of SARS-CoV-2 antibody assays. |
| 32717066 | We identified adults hospitalized with COVID-19, where cohort entry was the date of hospitalization. |
| 32717854 | The emergence of the COVID-19 outbreak at the end of 2019, caused by the novel coronavirus SARS-CoV-2, has, to date, led to over 13.6 million infections and nearly 600,000 deaths. |
| 32718020 | Overall, the review aims at presenting update-to-date details, so as to enhance awareness of potential therapeutics, and thus, to catalyze their appropriate use in combating the pandemic. |
| 32719490 | Since the differences in the CoVID-19 morbidity and mortality may depend on the different timing of the epidemics in each country, we applied the date of first documented CoVID-19 in each country as a proxy of susceptibility, with a statistical control for population size effects. […] The prevalence of toxoplasmosis co-varies negatively, while the date of first CoVID-19 co-varies positively with GDP per capita across countries. […] Further, to control for the strong spatial autocorrelation among countries, we carried out a Spatial Structure Analyses of the relationships between the date of first CoVID-19, prevalence of toxoplasmosis, and GDP per capita. |
| 32719673 | Considering the importance of the ongoing coronavirus crisis, we decided to evaluate genomes of all coronaviruses sequenced to date (stated more broadly, the order Nidovirales) to determine if they contain non-canonical nucleic acid structures. |
| 32719683 | In such a rapid-paced field, up-to-date systematic studies and meta-analysis will aid the scientific community to separate hype from hope and offer an unbiased position to the society and governments. |
| 32719737 | The Coronavirus (2019-Cov-2) infection Covid-19 is highly contagious caused by single stranded RNA virus (+ssRNA) with nucleocapsid and spreading widely all across the world and responsible for more than 3.6 million morbidity and 0.25 million mortality No specific treatment is available till date. |
| 32719874 | We characterized symptom profiles on the date of first positive RT-PCR test and described progression of symptoms over time. […] Eight (17%) individuals were asymptomatic at the date of first positive RT-PCR collection; two (4%) had preceding symptoms that resolved and six (13%) subsequently developed symptoms. |
| 32720611 | Up-to-date information about principles for administration of statins, antithrombotics, and antiarrhythmics is presented. |
| 32720703 | It was named COVID-19, and to date, thousands of cases of infection and death are reported worldwide. |
| 32721449 | However, most of initiatives taken were based on various hypotheses and till date no successful treatments have been achieved. |
| 32721782 | In Florida, New York, and Massachusetts, there was a general downward trend of vehicle collisions and vehicle related injuries over this time period, with statistically significant association between number of total vehicle collisions vs. date (p < 0.001), as well as number of vehicle related injuries vs. date (p < 0.001). |
| 32721808 | Various explanations, based on demographic, social and climatic factors, have been suggested to account for this variability, but these remain unverified to date. |
| 32722174 | To date, numerous measures have been applied by the government and the medical community during the early stages of the COVID-19 outbreak including the reporting of methods for diagnostic testing, patient classification, the introduction of drive-through screening centers, COVID-19 preventive measures, implementation of government policies for the shortage of face masks, and entry restrictions. |
| 32722715 | A limitation of the model is that count data by date of onset are required, and these are not available in all countries. |
| 32723442 | To the best of author’s knowledge, there is no comprehensive review on COVID-19 till date. |
| 32723447 | The disease started as an epidemic in China in December 2019 that later achieved a pandemic potential spreading to over 210 countries with more than 3.5 million confirmed cases and close to 250,000 deaths till date. |
| 32724171 | SARS-CoV-2 itself is not a recombinant of any sarbecoviruses detected to date, and its receptor-binding motif, important for specificity to human ACE2 receptors, appears to be an ancestral trait shared with bat viruses and not one acquired recently via recombination. […] Bayesian evolutionary rate and divergence date estimates were shown to be consistent for these three approaches and for two different prior specifications of evolutionary rates based on HCoV-OC43 and MERS-CoV. |
| 32724793 | In this article, all reported cases to date were collected and classified under 6 major groups: maculopapular rash, urticaria, chilblain, vesicular lesions, livedo reticularis, and petechiae. |
| 32725453 | To date, the clinical importance of chronic liver diseases among COVID-19 infection has remained undefined. |
| 32725833 | To date, coronavirus disease 2019 (COVID-19) has infected millions of people worldwide. |
| 32726185 | The estimated date of SARS-CoV-2 introduction into Brazil was consistent with epidemiological data from the first case of a returned traveller from Lombardy, Italy. |
| 32726230 | To date, coronavirus disease-2019 (COVID-19) has spread to over 200 countries, leading to over 1.6 million cases and over 99,000 deaths. |
| 32727613 | Two hundred and seventy-fiveparticipants were recruited and completed first month follow-up until date. […] Thus, 275 is the total number of participants included until date. |
| 32727861 | To date, COVID-19 cases have been reported in 54 out of 55 African countries. |
| 32728951 | Up to date, after 6 weeks of systematic execution of swabs no physician, nurse or other individual of the staff has been found positive to COVID-19. |
| 32729892 | Models developed by the Institute for Health Metrics and Evaluation (IHME) were used to estimate the anticipated duration of suspension by using the date that no ventilators would be required to for COVID-19 patients. |
| 32730095 | To date, there is no effective medicine available in the market which is effective in COVID-19. […] Till date, it has claimed millions of death worldwide. |
| 32730238 | Interviews were conducted 14-21 days after the test date. […] Respondents were asked about demographic characteristics, baseline chronic medical conditions, symptoms present at the time of testing, whether those symptoms had resolved by the interview date, and whether they had returned to their usual state of health at the time of interview. […] Among 292 respondents, 94% (274) reported experiencing one or more symptoms at the time of testing; 35% of these symptomatic respondents reported not having returned to their usual state of health by the date of the interview (median = 16 days from testing date), including 26% among those aged 18-34 years, 32% among those aged 35-49 years, and 47% among those aged ≥50 years. |
| 32732010 | In conclusion, this is the largest case series to-date of COVID-19 positive patients presenting with STEMI and spans 4 countries. |
| 32732190 | Updates may occur for up to two years from the date of original publication. |
| 32732316 | To date, therapy and review of known paediatric patients with IBD has continued. |
| 32732586 | It is essential for both the clinicians and pathologists to maintain up-to-date knowledge of this continuously evolving topic in the midst of the current pandemic. |
| 32734689 | To date, the task force has approved 80 guidance statements: 36 with moderate and 44 with high consensus. |
| 32734810 | To date, effective treatment remains elusive. |
| 32735524 | Up-to-date scientific evidence in this field was described in the form of a narrative and easy-to-read review. |
| 32735546 | This ensures providing up to date evidence of the fast development of this disease. |
| 32736407 | From available published data to date, we can conclude that the prognosis of COVID-19 positive neonates is good with no mortality. |
| 32736418 | Methods: SEIR dynamics model was used to fit daily onset infections to search the start date of this resurgent COVID-19 epidemic in Beijing. |
| 32736592 | TACTIC-E Protocol version number 1.0 date May 27th, 2020. […] The end trial date will be 18 months after the last patient’s last visit and cannot be accurately predicted at this time. |
| 32736597 | Since up to date reduced evidence about COVID-19 infection epidemiology, the continuous update of diagnostic and therapeutic approaches, the sample size estimation could be updated after a one third of population will be recruited and eventually modified according to a substantial protocol amendment. […] The PROTECT trial is registered in the EudraCT database (no. 2020-001501-24) and in ClinicalTrials.gov (NCT04363827), date of registration 24 April 2020. |
| 32737627 | The final follow-up date was March 2, 2020. |
| 32738881 | Thus, to track the current hotspots, and highlight future directions, we performed a bibliometric analysis to obtain an approximate scenario of COVID-19 to date. |
| 32739397 | Coronavirus Disease 2019 (COVID-19) has rapidly become a global pandemic, with over 1.8 million confirmed cases worldwide to date. |
| 32740067 | The effect of these guidelines on utilization of vitreoretinal care has not been explored to date. |
| 32740374 | Men reported the date they become concerned about COVID-19 and whether they engaged in sexual behavior with regular or casual partners or “fuckbuddies” in the 6 months before becoming concerned about COVID-19 (hereafter referred to as “before COVID-19”), and following the date, they become concerned about COVID-19 (hereafter referred to as “since COVID-19”). […] Before and since COVID-19 was based on individual participants’ own perceived date of becoming concerned about COVID-19. |
| 32740530 | To date, pancreatitis has not yet been reported in either acute SARS-CoV-2 infection in children or the subsequent inflammatory syndrome. |
| 32740720 | These finding comprise the most comprehensive report of COVID-19 tracheostomy decannulation to date and will assist service planning for future peaks of this pandemic. |
| 32740858 | To date, only remdesivir and dexamethasone have demonstrated a positive response in a prospective, randomized trial for the treatment of patients with COVID-19. |
| 32740925 | A review was conducted of 525 otolaryngology patients at a tertiary-care referral center with scheduled visits requiring rescheduling to a future date or a telemedicine visit. |
| 32741719 | The self-reports include the date of the transaction, the types of illicit drugs bought/sold, and whether the shipment of the illicit drugs succeeded, had issues (ex. unusually long delivery, an error in the type of drug shipped, quantity or concentration of the drug), or failed. |
| 32742034 | Delaying the start date of control measures by only 3 days would have increased the estimated 30 699 confirmed cases of COVID-19 by 1 March 2020 in regions outside Wuhan by 34.6% (to 41 330 people). |
| 32742059 | However, to date, there has been little investigation into the implications of the ‘Telegram’ application for online medical education and training. |
| 32742564 | To date, the safety and feasibility of stem cell and extracellular vesicles administration have been confirmed by numerous phase I/II trials in patients with COPD, acute respiratory distress syndrome, bronchial dysplasia, idiopathic pulmonary fibrosis, pulmonary artery hypertension, and silicosis. |
| 32742978 | This article reviews the characteristics of COVID-19-induced AKI largely based on up-to-date studies in the hope that it will be helpful in the current global fight against and treatment of COVID-19. |
| 32742979 | To date, all patients had been discharged successfully from Centro Hospitalar Conde de São Januário, a designated hospital to manage all COVID-19 patients in Macao. |
| 32744757 | To date, the outbreak of the novel coronavirus (COVID-19) has infected more than 5 million people and caused around 350 000 deaths globally. |
| 32745593 | To reduce the shortage of N95 respirators and surgical masks during the COVID-19 pandemic, stockpiled equipment beyond its expiry date could be released. |
| 32746922 | The severe acute respiratory syndrome virus SARS-CoV-2, a close relative of the SARS-CoV virus, is the cause of the recent COVID-19 pandemic affecting, to date, over 14 million individuals across the globe and demonstrating relatively high rates of infection and mortality. |
| 32747329 | To avoid misuse of personal protective equipment (PPE), ensure health care workers’ safety, and avoid shortages, effective communication of up-to-date infection control guidelines is essential. |
| 32748331 | Although various clinical trials are being conducted on renin- angiotensin- system inhibitor, till to date there is no standard treatment protocol approved for critically ill COVID-19 positive cases with pre-existing hypertension. |
| 32748582 | To date, COVID-19, with its high infectivity, has killed more people than severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) combined (Wu and McGoogan, 2020). |
| 32750135 | The literature to date has focused heavily on issues surrounding the quality of seroprevalence tests and less on the sampling methods that ultimately drive the representativeness of resulting estimates. |
| 32750378 | To this end, we conducted a systematic meta-analysis of histopathologic observations to date and review the reported findings. |
| 32750960 | To slow the spread of virus infections and better respond for community mitigation, by advancing capabilities of artificial intelligence (AI) and leveraging the large-scale and up-to-date data generated from heterogeneous sources (e.g., disease related data, demographic, mobility and social media data), in this work, we propose and develop an AI-driven system (named α-Satellite), as an initial offering, to provide dynamic COVID-19 risk assessment in the United States. |
| 32751633 | To date, health disparities are associated with COVID-19 mortality among underserved populations. |
| 32752129 | Throughout this comprehensive review, we describe the similarities and differences between both conditions and the possible pathophysiological and therapeutic-based mechanisms leading to the low incidence and severity of COVID-19 reported in PAH/CTEPH patients to date. |
| 32753143 | To date, the effects of any pandemic on telestroke service lines have not been described. |
| 32753375 | The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. |
| 32754298 | We, therefore, decided to conduct this assessment of AFP performance from 2012 to 2019 in the ESA sub-region have evidence documentation and support the certification process of the WHO AFRO region. we reviewed all reported acute flaccid paralysis (AFP) cases from 19 countries in the ESA sub region with the date of onset of paralysis from 1 January 2012 to 31 December 2019. |
| 32754756 | From the start date of the epidemic in Korea (18 February 2020), the time to peak and plateau were 15.2 and 25 days, respectively. |
| 32755231 | To date, there is no approved vaccine or specific therapy against COVID-19, but many trials are ongoing with some of them showing promising results. |
| 32755724 | According to clinical information, the incidence of vertical transmission of SARS-CoV-2 is limited to date. […] As the frequency and molecular mechanisms of intrauterine vertical transmission of SARS-CoV-2 have not been determined to date, intensive clinical examinations by repeated ultrasound and fetal heart rate monitoring are strongly recommended for pregnant women infected with COVID-19. |
| 32755836 | Till date, there is no approved medicine/treatment to cure COVID-19, whereas, vaccine development efforts are going on high priority. |
| 32756480 | To date, there are no therapies or vaccines that are proven to be effective against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). […] The most promising therapy to date is remdesivir, which is US Food and Drug Administration (FDA) approved for emergency use in adults and children hospitalized with severe suspected or laboratory-confirmed COVID-19. |
| 32757751 | We report the largest case series to date of cerebrovascular complications of COVID-19 and compare with stroke patients without infection. […] Demographic, clinical, laboratory, imaging, and outcome data were collected, and cases were compared with date-matched controls without COVID-19 from 1 year prior. |
| 32758298 | Date of trial registration: 10 July 2020. |
| 32758659 | The follow-up censoring date was 17 April 2020. |
| 32759006 | The Evidence possibly supporting or disputing this hypothesis is reviewed, however the major problem with the hypothesis is that to date no coronavirus has ever been isolated from arthropods. |
| 32759645 | The new respiratory infectious disease coronavirus disease 2019 (COVID-19) that originated in Wuhan, China, in December 2019 and caused by a new strain of zoonotic coronavirus, named severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), to date has killed over 630,000 people and infected over 15,000,000 worldwide. |
| 32760206 | COVID-19 is a public health emergency that has rapidly spread to over 200 countries and regions, and no effective treatment has been established to date. |
| 32761248 | Third, closure taxed personal coping resources but most were able to cope using thought-management (e.g., distraction, focusing on positives), getting mentally and physically fit for next treatments, strengthening their social network, and keeping up-to-date. |
| 32761260 | A date-matched control group (n = 205) of patients from 2019 was used for comparison. |
| 32761402 | Demographic and laboratory data closest to the CT date were recorded. |
| 32761974 | This invited commentary is a series of questions to Dr Mikhail Kazachkov, a pediatric pulmonologist at New York University, about his experiences to date in a major COVID-19 “hotspot” and his thoughts about how other pediatric pulmonologists facing this situation can best support their colleagues. |
| 32762250 | To date, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has infected nearly 600 times more people and resulted in 200 times more deaths relative to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV) combined. |
| 32762270 | This systematic review presents up-to-date evidence on the use of telemedicine and provides data for organisations considering its use in the current COVID-19 pandemic and beyond. |
| 32762411 | To date, ∼463,000 people died worldwide due to this disease. |
| 32762537 | The ongoing pandemic COVID-19 (COrona Virus Immuno Deficiency-2019) which is caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome-CoronaVirus-2) has emerged as a pandemic with 400,000 plus deaths till date. |
| 32762735 | Based on the scientific evidence accumulated to date, our view is that SARS-CoV-2 is not spread by the airborne route to any significant extent and the use of particulate respirators offers no advantage over medical masks as a component of personal protective equipment for the routine care of patients with COVID-19 in the health care setting. |
| 32762834 | Only limited evidence has been available to date on the accuracy of systematic low-dose chest computed tomography (LDCT) use in the diagnosis of COVID-19 in patients with non-specific clinical symptoms. |
| 32763263 | To date, the most utilized definition of ‘most at risk’ for COVID19 morbidity and mortality has focused on biological susceptibility to the virus. |
| 32763338 | For instance, numerical simulations suggest that if the lockdown measures in South Africa were implemented a week later than the 26 March, 2020 date it was implemented, this will result in the extension of the predicted peak time of the pandemic, and causing about 10% more cumulative deaths. |
| 32764257 | We explore why research to date has failed to show convincing evidence for environmental modulation of COVID-19, and discuss directions for future research. |
| 32764417 | Based on the current published evidence, herein we summarize the origin, genetics, epidemiology, clinical manifestations, preventions, diagnosis and up to date treatments of SARS-CoV-2 infections in comparison with those caused by SARS-CoV and MERS-CoV. |
| 32764454 | We herein provide a comprehensive and up-to-date overview of the role of ACE-2 and TMPRSS2 genes, as key entry elements as well as therapeutic targets for SARS-CoV-2 infection, which can help to better understand the applications and capacities of various remedial approaches for infected individuals, especially those with lung cancer. |
| 32765185 | Participants were asked whether they had experienced fever or other cold symptoms between February 17, 2020 and the date of the survey. |
| 32766112 | At the date of this evidence map´s publication, there is no evidence of specific treatments for COVID-19. |
| 32766414 | The date is two weeks after the government call of the Republic of Indonesia to carry out Physical Distancing to anticipate the COVID-19 Global Pandemic. |
| 32766546 | Only 3.6% of patients required an ICU admission and 1.7% were dead at the study’s cutoff date. |
| 32766756 | Date of hospitalization. |
| 32766927 | Using an online questionnaire, we asked Japanese board-certified radiologists to register their patients’ information including patient age and sex, the CT examination date, the results of PCR test for COVID-19 infection, CT findings, and the postal code of the medical institution that performed the CT. |
| 32767355 | The selection of the countries was based on the daily basis mean temperature from the date of appearance of the initial cases of COVID-19, Dec 29, 2019 to May 12, 2020. […] The data on the global outbreak of COVID-19, daily new cases and deaths were recorded from World Health Organization, and daily information on temperature and humidity was obtained from metrological web “Time and Date”. |
| 32767742 | To date, there have been no COVID-19 infections among the bronchoscopy team staff, whereas the overall Hospital staff COVID-19 prevalence rate has exceeded 13.5% (667/4949). |
| 32768308 | Children in the Asia-Pacific region, as with children all over the world to date, have fared better than older adults. |
| 32769921 | According to the retrieval strategies, randomized controlled trials (RCTs) on the Shufeng Jiedu capsule for COVID-19 were obtained from CNKI, WanFang, VIP, PubMed, Embase and Cochrane Library, regardless of publication date, or language. |
| 32770414 | To date, only few cases of GBS associated with this infection have been described. |
| 32770825 | To date, there are no proven effective therapies for this virus. […] To date, a considerable number of bacterial strains have been resistant to various antibiotics such as azithromycin, and the overuse could render those or other antibiotics even less effective. |
| 32770973 | To this date little information exists on the effects, clinical course and outcome of the COVID-19 among patients undergoing transplantation. |
| 32771034 | The intended completion date is December 31, 2020. […] Date of trial registration: May 26, 2020. |
| 32771068 | The current study protocol is version 1.0 (20 July 2020) TRIAL REGISTRATION: This study was prospectively registered in the ISRCTN registry (registration number ISRCTN43900695 , date of registration: 8 April 2020). |
| 32771480 | Factors predicting willingness to change and vaccinate included child’s up-to-date vaccination status (aOR 2.03, 95% CI 1.29-3.32, P = .003); caregivers’ influenza vaccine history (aOR 3.26, 95% CI 2.41-4.40, P < .010), and level of concern their child had COVID-19 (aOR 1.09, 95% CI 1.01-1.17, P = .022). |
| 32771639 | No study has evaluated whether the presence of antibodies to SARS-CoV-2 confers immunity to the infection relapse but however, to date, no human reinfections with SARS-CoV-2 have been confirmed. |
| 32772318 | Based on the date of declaration of national lockdown, the cohort was separated into two groups: ‘pre-COVID time’ (PCT), including 86 patients, and ‘COVID time’ (CT), consisting of 74 patients. |
| 32772434 | Our results show that urologists lack up-to-date knowledge of preferred protocols for personal protective equipment selection and use, social distancing, and coronavirus disease 2019 testing. |
| 32773286 | We provide and describe a cross-functional, collaborative on-the-ground adaptive application of eTCB initially piloted at two hospitals and subsequently reproduced at 16 additional hospitals and health systems in the US to date. |
| 32773618 | ICU follow-up programs or peer support groups remain important interventions to learn about and address the multifaceted challenges of critical illness survivorship, but there is little evidence of benefit to date. |
| 32773996 | As of this article’s publication date, COVID-19 has spread to approximately 200 countries and territories, with over 4.3 million infections and more than 290,000 deaths as it has escalated into a global pandemic. |
| 32774009 | We have not observed any mortality, to date in the Non NOF procedures carried out. |
| 32774178 | Given the high mortality rate and economic damage to various communities to date, great efforts must be made to produce successful drugs and vaccines against 2019-nCoV infection. |
| 32774918 | Using publicly available data for confirmed COVID-19 cases from the Korea Centers for Disease Control and Prevention from January 20, 2020, to April 30, 2020, we undertook descriptive analyses of cases stratified by sex, age group, place of exposure, date of confirmation, and province. |
| 32775771 | Here, we present steps taken to date to flatten the curve at the radiation oncology division of a tertiary cancer center with the goal of mitigating risk of exposure among patients and staff, and optimizing resource utilization. |
| 32776298 | To date no trial comparing hydroxychloroquine (HCQ) and lopinavir/ritonavir (LPV/RTV) has been performed. |
| 32776573 | This review was conducted to evaluate the impact of CPT in COVID-19 patients based on the publications reported to date. |
| 32777758 | To date, there are no confirmed specific therapies, and prevention and management of AKI should follow established guidelines. |
| 32777861 | This is the largest study of baseline immune seroconversion in maternity healthcare workers conducted to date and reveals that one out of six were seropositive, of whom one out of three were asymptomatic. |
| 32778180 | To date, there is a major lack of understanding of the transmission dynamics and epidemiological characteristics of the disease in India, inhibiting effective measures to control the pandemic. |
| 32778421 | To date, seven human CoVs were identified including the alpha-CoVs HCoVs-NL63 and HCoVs-229E and the beta-CoVs HCoVs-OC43, HCoVs-HKU1, the severe acute respiratory syndrome-CoV (SARS-CoV), the Middle East respiratory syndrome-CoV (MERS-CoV) and the novel virus that first appeared in December 2019 in Wuhan, China, and rapidly spread to 213 countries as of the writing this paper. |
| 32779002 | Of these, 25 were selected from the Google play store and Apple App store in India, and 19 each from the UK and US. 18 apps were developed for sharing up to date information on COVID-19, and 8 were used for contact tracing while 9 apps showed features of both. |
| 32779309 | Most up-to-date evidences about how SARS-CoV-2 affected patients especially in pregnancy were collected by conducting a comprehensive search of medical literature electronic databases. |
| 32779341 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causing coronavirus disease 2019 (COVID-19) is the biggest pandemic of our lifetime to date. |
| 32780206 | To date, the disease has affected almost all countries in the world. […] The DOTF has positioned us well to confront the many challenges to date. |
| 32780376 | To date, few data have been obtained of the prevalence of SARS-CoV-2-antibodies in general population and in asymptomatic outpatients in Germany.From March 26 to June 4 2020, 415 asymptomatic outpatients were tested prospectively in Northrhine-Westfalia (Germany), to detect SARS-CoV-2-IgG-antibodies. |
| 32780415 | The present paper is an up-to-date review that discusses the available research regarding the implications of coronavirus infection in COPD. |
| 32781623 | Intracranial bleeding was diagnosed on computed tomography (CT) of the brain within one month of the date of COVID-19 diagnosis. |
| 32782784 | To date, information about the clinical course of COVID-19 in pre-existing pulmonary arterial hypertension is lacking, and it is thus unknown whether pulmonary arterial hypertension belongs to the risk factors of severe COVID-19 disease. |
| 32784826 | Despite this, to date, very few studies have been performed concerning autoptic specimens. |
| 32784922 | Results: Although many agents have been proposed as possible treatment, to date, any of the potential drugs against SARS-CoV-2 has shown to be safe and effective for treating COVID-19. |
| 32785155 | The approach presented in this paper contributes to the establishment of a methodology framework that may equip decision-makers with up-to-date estimations of health crisis effects on economic parameters of food availability and access to staples in food-insecure communities. |
| 32785162 | In this review all the up-to-date findings, concerning the association between COVID-19 and cancer, are reported. |
| 32785701 | We have trained a machine learning model to analyze the correlation between SARS-CoV-2 test results and 20 routine laboratory tests collected within a 2-day period around the SARS-CoV-2 test date. |
| 32789282 | In light of the considerable COVID-19 disparities observed, this study sought to assess the race reporting and representation among COVID-19 therapeutic studies published to date. […] For each study, the date published, treatment investigated, study design, race/ethnicity of participants, sample size and study site were recorded. […] Six studies (n = 3, observational; n = 3, randomized clinical trial) have been published to date with participants in the United States. |
| 32791241 | However, research to date is at high risk of bias, and randomized control trials are desperately needed to determine the efficacy and safety of this therapeutic option. |
| 32791259 | To date, only 2 nurses working in China who contracted SARS-CoV-2 have died from COVID-19 in the early period of the epidemic (February 11 and 14, 2020). |
| 32792023 | Transmitters were individuals who had onset date prior to their infected social contact. |
| 32792167 | To date, there are no approved antiviral drugs or vaccines against this transmissible disease. |
| 32792492 | The final follow-up date observed was April 15th, 2020. |
| 32793245 | However, to date, no licensed vaccine exists, neither for SARS-CoV-2 nor for the closely related SARS-CoV or Middle East respiratory syndrome-CoV. |
| 32793722 | To date, although many studies have reported on the computed tomography (CT) manifestations of COVID-19, the vascular enlargement sign (VES) of COVID-19 has not been deeply examined, with the few available studies reporting an inconsistent prevalence. |
| 32793722 | To date, although many studies have reported on the computed tomography (CT) manifestations of COVID-19, the vascular enlargement sign (VES) of COVID-19 has not been deeply examined, with the few available studies reporting an inconsistent prevalence. |
| 32793722 | To date, although many studies have reported on the computed tomography (CT) manifestations of COVID-19, the vascular enlargement sign (VES) of COVID-19 has not been deeply examined, with the few available studies reporting an inconsistent prevalence. |
| 32793722 | To date, although many studies have reported on the computed tomography (CT) manifestations of COVID-19, the vascular enlargement sign (VES) of COVID-19 has not been deeply examined, with the few available studies reporting an inconsistent prevalence. |
| 32793722 | To date, although many studies have reported on the computed tomography (CT) manifestations of COVID-19, the vascular enlargement sign (VES) of COVID-19 has not been deeply examined, with the few available studies reporting an inconsistent prevalence. |
| 32793722 | To date, although many studies have reported on the computed tomography (CT) manifestations of COVID-19, the vascular enlargement sign (VES) of COVID-19 has not been deeply examined, with the few available studies reporting an inconsistent prevalence. |
| 32793722 | To date, although many studies have reported on the computed tomography (CT) manifestations of COVID-19, the vascular enlargement sign (VES) of COVID-19 has not been deeply examined, with the few available studies reporting an inconsistent prevalence. |
| 32793722 | To date, although many studies have reported on the computed tomography (CT) manifestations of COVID-19, the vascular enlargement sign (VES) of COVID-19 has not been deeply examined, with the few available studies reporting an inconsistent prevalence. |
| 32794454 | Laboratory test alterations have been described in COVID-19 patients, but differences with other pneumonias have been poorly investigated to date, especially in Caucasian populations. |
| 32794463 | Currently, there are several experimental therapies with demonstrated in vitro activity against COVID-19 used in clinical practice, including hydroxychloroquine, remdesivir, interleukin-6 pathway inhibitors, and convalescent plasma; however, to date no agent has proven efficacy against COVID-19. |
| 32795148 | Up to date over a hundred crystallographic structures of SARS-CoV-2 Mpro have been deposited to Protein Data Bank. |
| 32795149 | As revealed in the summary independent-samples t test and Hedges’ g values, both Oceanian countries (Australia and New Zealand) reacted differently compared to the other countries, which may have played a role in their low death and infection rates to date. |
| 32795214 | Of each trial, medicines assessed, design, sample size, registration date, study start and study completion dates, and type of patients were registered. 106 trials were identified, 62 in Europe and 46 in the USA ─with two conducted in both regions. |
| 32796045 | Non-rheumatic controls were randomly sampled 1:1 and matched by age, sex and PCR date. |
| 32798227 | Explaining the present situation and best available statistics of the disease, the velocity the disease is spreading and our approximate predicted date its subsidence or partial remission. |
| 32798444 | Progress in SARS-CoV-2 vaccine development to date has been faster than for any other pathogen in history. |
| 32800868 | In the context of the COVID-19 worldwide pandemic, an up-to-date review of current challenges in addictions is necessary. |
| 32802142 | The SARS-CoV-2 infection has widely spread to become the greatest public health challenge to date, the COVID-19 pandemic. |
| 32802586 | Objective: In this brief review, the authors examine the latest available evidence to date regarding the neurological implications of COVID-19 and how the novel coronavirus might possibly impact patients with pre-existing neurological conditions. |
| 32803146 | The commonest cardiac presentation to date is acute heart failure resulting from biventricular or left ventricular hypokinesis and elevation of cardiac troponins. |
| 32803255 | To date (29 April 2020), the Italian penitentiary system is housing 161 minors (147 males), most of them in pre-trial custody, as well as 50 children <3 y of age residing with their mothers in detention. |
| 32806657 | In 2002 and following years, the scenario changed dramatically with the advent of the new more pathogenic CoVs, including Severe Acute Respiratory Syndome (SARS-CoV-1), Middle Eastern respiratory syndrome (MERS)-CoV, and the new zoonotic SARS-CoV-2, likely originated from bat species and responsible for the present coronavirus disease (COVID-19), which to date has caused 15,581,007 confirmed cases and 635,173 deaths in 208 countries, including Italy. |
| 32807047 | At present, the world is facing a global pandemic threat of SARS-CoV-2 or COVID-19 and till date, there are no clinically approved vaccines or antiviral drugs available for the treatment of coronavirus infections. |
| 32807209 | Azithromycin was widely used to treat severe SARS-CoV and MERS-CoV, but to date, no randomised data are available in any coronavirus infections. |
| 32809115 | The date in which the number of daily new deaths will fall below the rate of 3 deaths per million - the average level in which some countries start to relax the stay-at-home measures - was estimated. […] If the daily new deaths curve was bending today (i.e., about 1250 deaths per day), the predicted date would be on July 5. |
| 32810325 | There is no standardised and up-to-date education model for urology residents in our country. |
| 32810701 | To evaluate the diagnostic and prognostic performance of CT in patients referred for COVID19 suspicion to a French university hospital, depending on symptoms and date of onset. […] Sensitivity, specificity, negative and positive predictive values of first and expert readings were calculated together with inter reader agreement, with results of RT-PCR as standard of reference and according to symptoms and onset date. |
| 32810855 | However, to date, prospective studies are lacking. |
| 32811213 | Telemedicine, slow to become established in many countries to date, has also revolutionized practice in the current environment. |
| 32812834 | The variation in mortality rates reported to date likely reflects differences in the severity of illness of the evaluated populations. |
| 32812872 | Control group consisted of patients with new fractures admitted to the hospital in the same date range in 2018 and 2019. |
| 32812904 | The emerging SARS-CoV-2, a novel human coronavirus, caused the COVID-19 pandemic, with more than 9.5 million cases and 484 000 known fatalities to date (June 24th, 2020). |
| 32813298 | The Odd Ratio (OR) of anaemia related to the severe condition of COVID-19 was 3.47(95% CI: 1.02-11.75, P=0.046) and 3.77 (95% CI:1.33-10.71, P=0.013) after adjustment for baseline date and laboratory indices, respectively. |
| 32813575 | To date, nearly 600 research units and companies have claimed to have completed the development of NAT reagents. |
| 32813843 | We were unable to find any review of the literature or analysis on ongoing registered clinical trials that reported diagnostic tests, therapeutics, vaccines and devices for COVID-19 along with estimated enrollment, participants’ ages, study type, start and completion date, status, treatment/intervention and country. |
| 32814575 | However, to date no specific guidelines or strategies about mental health services of migrant workers have been released. |
| 32815174 | For ICU practitioners, management of acute respiratory failure, hemodynamics, and cardiovascular complications certainly are the key for the best treatment of these patients but to date specific data on supportive ICU care for these patients are lacking, and current recommendations are based on existing evidence from other viral infections and general intensive care management. |
| 32816200 | Based on the published scientific evidence published to date, we summarized herein the effects of different potential therapies and up-to-date clinical trials. |
| 32817375 | Studies to date have now demonstrated that in patients with COVID-19, these drugs are associated with significant QTc prolongation, as well as reports of ventricular arrhythmias. |
| 32817598 |
|
| 32819955 | The date when COVID-19 was declared an outbreak in Beijing was 20 January 2020. |
| 32820179 | Thousands of SARS-CoV-2 strains have been sequenced to date, providing a valuable opportunity to investigate the evolution of the virus on a global scale. |
| 32820359 | Since the majority of pain medicine centers have been closed to date, the question has arisen as to whether a resumption of regular care can be easily provided under the required protective measures. |
| 32820868 | To date, numerous studies have been conducted to evaluate the safety and efficacy of tissue engineering and regenerative medicine (TERM) products, including mesenchymal stem cells (MSCs), and their derivatives (eg, exosomes) for coronavirus infections, which could be applied for the COVID-19. |
| 32821884 | To date, no specific antiviral treatment has been confirmed. |
| 32821939 | The date of final follow-up was May 20, 2020. |
| 32822426 | To date, millions of infections and thousands of deaths have been reported worldwide, and the numbers continue to rise. |
| 32822955 | To date, the effects of the COVID-19 pandemic on neuro-trauma has not been reported. |
| 32823901 | In this review, we have compiled the up to date information about the origins, evolution, epidemiology, and pathogenesis of this disease. |
| 32825737 | To date, there are no vaccines or specific antiviral drugs to prevent or treat COVID-19. |
| 32825816 | None of these registered trial results was available during the timeframe of the pandemic, and the median date of publication was 213 days after the Public Health Emergency of International Concern ended. |
| 32826322 | However, to date, studies on protective immunity have been performed only in animal models and correlates of protection have not been established in humans. |
| 32826332 | Applying that logic to data on imported cases and local deaths in the United States through 12 March, we estimated that 108,689 (95% posterior predictive interval [95% PPI]: 1,023 to 14,182,310) infections occurred in the United States by this date. |
| 32827728 | Changes in encounter characteristics, viral testing patterns, and air pollution before and after Mar 17, 2020, the date public health interventions to limit viral transmission were enacted in Philadelphia, were assessed and compared with data from 2015 to 2019 as a historical reference. |
| 32828135 | Indeed, to date, a well-established therapy is still lacking. |
| 32829231 | Respondents felt that the most significant factor for work-related changes to mental health was keeping up to date with frequently changing guidelines and protocols related to COVID-19. |
| 32829962 | Through this review, we aim to provide an up-to-date summary of current evidence-based literature of hematological manifestations, their consequences and management including role of anticoagulation and drugs targeting cytokine storm in patients with SARS-CoV-2. |
| 32831521 | About 400,000 SARS-CoV2-positive patients have been declared ‘recovered’, although it is not clear to date what exactly that entails. |
| 32831936 | Till date, no pharmaceutical agent is known to manage in terms of prevention and treatment of coronavirus disease 2019 (COVID-19), the disease caused by a novel virus. |
| 32832913 | Relevant and up-to-date literature, media reports, and author experiences were included from Medline, national newspapers, and public clinical trial databases. |
| 32833771 | In this article, we explore the diagnostic modalities for COVID-19 based on the available information to date. |
| 32834156 | In the meantime, the number of reported new infections has been significantly reduced and the German healthcare system does not appear to be overburdened to date. |
| 32834243 | Here, we critically review the limited number of prototypes demonstrated to date that is based on a polymerase chain reaction (PCR) and has come close to fulfill this vision. |
| 32834559 | In real wastewater and in sewage sludge, to date studies on the influence of the different parameters on the inactivation of SARS-CoV-2 are not available. |
| 32834573 | Visualisation of reported data provides up-to-date condition monitoring, while daily model calibration allows for a continued and updated forecast of the current state of the pandemic. |
| 32834581 | Here we use an individual based model (IBM) to study how the duration, start date and intensity of quarantine affect the height and position of the peak of the infection curve. |
| 32834582 | We use the model to make predictions about the total expected number of infections in each country as well as the date when the number of infections will have reached 99% of this total. |
| 32834603 | A complete scenario is given to demonstrate the estimated pandemic life cycle along with the real data or history to date, which in turn divulges the predicted inflection point and ending phase of SARS-CoV-2. |
| 32834902 | This article aims at presenting an up-to-date review on the pathogenesis, diagnosis and complications of COVID-19 infection. |
| 32834946 | To date there are over 133 ongoing registered clinical studies on TCM/integrated traditional Chinese and Western medicine. |
| 32834947 | Unfortunately, neither drug nor vaccine has yet been approved to date to prevent and treat these diseases caused by CoVs. |
| 32834948 | There have been more than 4,400,000 reported cases of COVID-2019 and more than 300,000 reported deaths to date (16/05/2020). […] To date, there is no specific treatment proven effective against these viral infectious diseases. |
| 32834995 | We describe the measures implemented in the largest cancer centre in Singapore to continue optimal cancer care in spite of the ongoing pandemic, with no nosocomial infections reported in our centre to date. |
| 32835062 | To date, no drugs have demonstrated safety and efficacy in randomized controlled trials for patients with COVID-19. |
| 32835090 | To date, there is no approved therapeutics or effective treatment available to combat the outbreak. |
| 32835123 | However, no study to date has examined such climatic extensions for the growth or otherwise of the novel coronavirus in Africa. |
| 32835135 | To date there is no direct evidence from human or animal studies on the role of lung microbiome in modifying COVID-19 disease; however, related studies support that microbiome can play an essential role in developing immunity against viral infections. |
| 32835962 | We investigated the possibility that SARS-CoV-2 emerged in Italy earlier than that date, by analysing 40 composite influent wastewater samples collected - in the framework of other wastewater-based epidemiology projects - between October 2019 and February 2020 from five wastewater treatment plants (WWTPs) in three cities and regions in northern Italy (Milan/Lombardy, Turin/Piedmont and Bologna/Emilia Romagna). |
| 32836410 | This article sets out the advantages of this form of deliberation-which bears some similarity to certain types of citizen science-in the context of the UK government’s responses to Covid-19; both the confused decision making evident to date, and the forthcoming re-opening phases that will prioritise or advantage some constituencies over others. |
| 32836447 | This Viewpoint essay argues that timely, up-to-date surveys of public sector workers are an essential tool for identifying problems, resolving bottlenecks and enabling public sector workers to operate effectively during and in response to the challenges posed by the global pandemic. |
| 32836712 | Data of the date of onset, clinical details, laboratory results, history of travel, history of contact with positive case and control measures initiated were collected, analysed and compared. |
| 32836859 | However, to date there has been little attention given to what the consequences of the COVID-19 economic shock may be for the wildlife trade; the people who rely on it for their livelihoods; and the wildlife that is exploited. […] In this policy perspective, we argue that the links between the COVID-19 pandemic, rural livelihoods and wildlife are likely to be more complex, more nuanced, and more far-reaching, than is represented in the literature to date. |
| 32836862 | Our analyses show that, to date, differences in policy interventions have out-weighed socio-economic variation in explaining the range of death rates observed in the data. |
| 32837029 | However, to date, no study that we know of has identified what type of person is willing to fly during the COVID-19 pandemic. |
| 32837097 | Given the rapid pace of clinical information and discoveries, it is important for clinicians to be up to date with the latest, evidence-based treatment options available for this novel disease. |
| 32837113 | There are no approved antiviral drugs or vaccines for the treatment of human CoV infection to date. |
| 32837119 | Although after the continuous scientific efforts, we are still not having any specific drug or vaccine for the SARS-CoV-2 pathogen to date and there is an urgent need to develop a newer therapy to counter the COVID-19 global pandemic. |
| 32837137 | COVID-19 is a global health emergency and no clinically approved vaccines or antiviral drugs available to date. |
| 32837219 | There has been no vaccines or drugs available for the treatment of human coronavirus infections to date. |
| 32837240 | We outline the work to date on modelling spatially-explicit infective diseases and show that there are gaps that remain important to fill. |
| 32837241 | If relaxations are necessary, they should not be performed before this date and should be in small periods, no longer than 25 days. |
| 32837280 | The CPA week in comparison with date of lockdown and first reported case strongly correlates (Pearson’s r = - 0.86 to - 0.97) to cases, cases per unit area and cases per unit population, indicating earlier the mitigation strategy, lesser the number of cases. |
| 32837391 | To date, there have been zero health care worker transmissions in the department. |
| 32837414 | As our knowledge of the transmissibility of SARS-CoV-2 and the symptomatology and management of COVID-19 expands, orthopedic surgeons must remain up to date on the latest medical evidence and surgical perspectives. |
| 32837583 | However, a limited amount of research has been done to date in the context of how viral infections impact cancer at the cellular level and vice versa. |
| 32837696 | Italy has been the European country most affected by the COVID-19 pandemic to date and has been in social lockdown for the longest period of time compared to other countries outside China. |
| 32837713 | Proper understanding of the mechanics of the complex processes whereby the two-phase flow emitted by an infected individual disperses into the environment would allow us to infer from first principles the practical rules to be imposed on social distancing and on the use of facial and eye protection, which to date have been adopted on a rather empirical basis. |
| 32837836 | To date (22nd April 2020), the COVID-19 situation in Malta is a total confirmed cases of 444, of which 276 are active cases, 165 have recovered and there were three deaths. |
| 32837847 | To date, no specific drug for COVID-19 has been developed. |
| 32837889 | The COVID-19 pandemic has led to hardship for individuals across the globe, and research to-date has indicated a significant impact of the pandemic on mental health functioning. |
| 32837947 | While it is being recommended worldwide to postpone all elective surgeries to a later date, certain emergency procedures must be undertaken promptly but in a manner that minimizes the exposure of the surgeon and health care staff to the SARS-CoV-2. |
| 32837950 | Only 5 studies from the literature have mentioned any smell and taste disturbances after SARS-CoV-2 infection to date. |
| 32838116 | The American Academy of Sleep Medicine strongly urges sleep clinicians to continue postponing non-urgent care until a later date, if such a recommendation is made by state officials due to local conditions. |
| 32838146 | To date, few cases of COVID-19 meningitis have been confirmed, but it must remain in the differential diagnosis for patients with headache and fever. |
| 32838153 | Starting from Wuhan (China) where it was firstly reported, it rapidly spread to the rest of the world, causing a pandemic with more than 300,000 deaths to date. |
| 32838159 | To date, there is no definitive treatment for the new SARS-CoV-2 pandemic. |
| 32838283 | As the number of deaths due to COVID-19 is increasing rapidly and there is no specific treatment available to date, scientists are evaluating the effectiveness of already approved drugs as therapies against COVID-19, and the results were found to vary widely: from no significant effect being observed to a reduction in the time taken for clinical improvement. |
| 32838300 | Although artificial intelligence (AI)-based clinical decision support seemed to have matured, the application of AI-based tools for COVID-19 has been limited to date. |
| 32838447 | In this article, the data available to date are examined in order to provide better information, advice and treatment for pregnant women and newborns with SARS-CoV-2 and to provide suggestions for future research. |
| 32838713 | But exact biochemical mechanisms of these drugs towards COVID-19 have not been discovered to date. |
| 32839288 | To date, little is known on histopathological findings in patients infected with the new SARS-CoV2. |
| 32839763 | To date, the phenotypes of SARS-CoV-2-specific T cells remain poorly defined. |
| 32839923 | We conducted a retrospective observational study analysing all emergency visits occurring at a metropolitan psychiatric ED between March 19th and May 2nd 2019 and 2020 (the beginning/end date of the emergency state which Portugal was under due to COVID-19). […] Data regarding age, sex, diagnoses, admission date, discharge destiny and status were collected. |
| 32840606 | Based on the date of symptom onset in the remaining 41 cases, the period from exposure to illness ranged from 2 to 17 days. |
| 32842849 | The need to adapt to remote technology became the most difficult challenge to date for existing practice models. |
| 32843098 | The protocol with code 1264, version 3.0 on date: May 13, 2020 is approved by the local Ethics Committee. |
| 32843598 | To date, few early post-liver transplantation SARS-CoV-2 infected recipients have been published, but only one was an early postoperative infection. |
| 32844105 | The datasets mainly focus on two major fields, first one is First Case which consists of information of Date of First Case(s), Number of confirm Case(s) at First Day, Age of the patient(s) of First Case, Last Visited Country and the other one First Death information consist of Date of First Death and Age of the Patient who died first for every Country mentioning corresponding Continent.This dataset also can perform a bunch of predictions using Machine Learning applications, like -how fast the virus is spreading, affect rate, death rate, death rate and able to represent comparison between other pandemics. |
| 32844133 | We use the collected data of the new coronavirus pandemic reported up to date July 30, 2020 in India, the Syrian Arab Republic, the United States, France, Nigeria, Yemen, China and Russia. |
| 32844985 | This outbreak quickly reached a pandemic status, affecting at least 185 countries and territories to date on all continents. |
| 32845250 | The research team performed a literature review, searching relevant and up to date information from the literature. |
| 32845868 | Women were stratified into two groups based on date of delivery in relation to the start of the COVID-19 pandemic in New York (Mid-March 2020); those delivering before or during the COVID-19 pandemic. |
| 32847926 | No restriction regarding the language, publication date or setting will be employed. |
| 32848729 | The objectives of this review are to provide up-to-date information on the pharmacology and clinical research on CPMs in the treatment of COVID-19, discuss the research findings, and to better guide clinical application and scientific research on CPMs in the treatment of COVID-19. |
| 32848893 | Several studies till date have indicated a dysregulated host immune response as the major cause of COVID-19 induced mortality. |
| 32849149 | We suggest practical tips for both healthcare workers and organizations and embed this within up-to-date scientific literature. |
| 32849666 | To date the pathophysiology of COVID-19 remains unclear: this represents a factor determining the current lack of effective treatments. |
| 32849867 | The pathophysiology for SARS-CoV-2 has not been well elucidated, and diverse hypotheses to date have been proposed. |
| 32849934 | Despite high morbidity and mortality of ongoing coronavirus disease 2019 (COVID-19) pandemic, no specific therapy has been established till date. |
| 32850925 | To date, 20 (9%) patients have retested positive for SARS-CoV-2 RNA after recovering and being discharged. |
| 32851129 | To date, the studies that have been published show the presence of elevated D-dimer levels in both the adult and pediatric populations and the measured level correlates with disease severity. |
| 32851910 | Novel Coronavirus or SARS-CoV-2 has received worldwide attention due to the COVID-19 pandemic, which originated in Wuhan, China leading to thousands of deaths to date. |
| 32852058 | However, to date, no approved vaccines or drugs against CoV infections are available. |
| 32852240 | In particular, studies using validated olfactory tests are very rare to date. |
| 32852721 | ACEI/ARB use is not associated with either an increased or decreased risk of all-cause mortality, compared with CCB use, in the largest cohort of hospitalised COVID-19 patients exposed to these drugs studied to date. |
| 32853310 | To date all the drugs described in this review need clinical studies to validate their use. |
| 32853663 | In addition, to date incidence data are underestimated in all countries and to a lesser extent also mortality data. |
| 32855070 | Search items were considered from the nature of the articles, date of publication, aims and findings in relation to use of laparoscopic surgery during COVID-19. […] There is no scientific evidence to date for the transmission of COVID-19 by laparoscopic surgery. |
| 32855187 | In this clinical case series, we report our experience to date with neurologic complications of extracorporeal membrane oxygenation therapy for COVID-19 Acute Respiratory Distress Syndrome. |
| 32856766 | To derive clinical sensitivity of PCR, we identified 209 PCR-positive SARS-CoV-2 patients with multiple PCR test results (624 total PCR tests) and calculated daily sensitivity from date of symptom onset or first positive test. |
| 32858940 | To date, no specific antiviral therapy is available for patients with SARS-CoV-2 infection. |
| 32861744 | In this review, we provide an up-to-date overview of the current knowledge of the enzymatic and cytokine-like effects of tPA and describe the role of tPA and plasminogen receptors in the regulation of the inflammatory response with emphasis on the cytokine storm syndrome such as observed during coronavirus disease 2019 or macrophage activation syndrome. |
| 32863610 | The resulting model allows one to infer, among others, the general peak date, the ending date, and the total number of cases as well as to compare the level of difficult imposed by the pandemic among territories. |
| 32863612 | Since the appearance of the first case of COVID-19 in Morocco on March, 02, 2020, the cumulative number of reported infectious cases continues to increase and, up to date, the peak-time of infection is not reached yet. |
| 32863675 | No cure is available for this condition till date. |
| 32864070 | The authors review the up-to-date scientific evidence of SARS-CoV-2 transmission to demystify and explain the exposure control options available for ophthalmic workplace and offer insights from an industrial hygiene standpoint. |
| 32864104 | Literature reviews of research exploring school closure to date have focused upon epidemiological effects; there is an unmet need for research that considers the multiplicity of potential impacts of school closures. […] While dependent upon the nature of epidemics experienced to date, we aim for the model to provide a starting point for theorising about school closures in general, and as part of a wider system that is influenced by contextual and population factors. |
| 32864299 | Till date, no drugs have been discovered to treat COVID-19 patients, and therefore, a considerable amount of interest has been shown in repurposing the existing drugs. […] The existing literature hints that till date, the role of CQ/HCQ in COVID-19 may be sceptical, and further studies are warranted for obtaining a therapeutic option that could be effectively used across the world to rise out from this pandemic. |
| 32864545 | To date, there is no knowledge of the role children (prepubescent, ages 9-13 years) play as “silent” vectors of the virus, with themselves being asymptomatic. |
| 32864575 | Although frantic global efforts for developing safe and effective prophylactic and therapeutic agents are on, no licensed antiviral treatment or vaccine exists till date. |
| 32864815 | However, the huge amount of studies makes it challenging to keep up to date with the literature on COVID-19 therapeutic development. |
| 32865556 | The primary outcome was the percentage change in COVID-19 cases 5 days from the exposure date. |
| 32867008 | The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents a new public health problem, with a total of 10.577.263 documented COVID-19 cases worldwide and 513.441 deaths up to the present date. |
| 32867137 | In this review, we will examine the cardiac involvement associated with SARS-CoV-2 infection, focusing on the pathophysiological mechanism underlying manifestations and their clinical implication, taking into account the main scientific papers published to date. |
| 32867149 | While food insecurity (FI) has been extensively studied in many countries, there have been few empirical contributions in Poland to date. |
| 32867349 | Neither therapeutic agents nor vaccines have been developed to date, which is a major drawback in controlling the present global pandemic of COVID-19 caused by SARS coronavirus 2 (SARS-CoV-2) and has resulted in more than 20,439,814 cases and 744,385 deaths. |
| 32867852 | Clinical Trials Registry of India: CTRI/2020/05/025067 (prospectively registered) Date of registration: 6th May 2020 FULL PROTOCOL: The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). |
| 32868092 | To date, none are FDA approved beyond emergency use authorization (EUA), and 2. |
| 32869558 | In conclusion, this study showed the up-to-date evidence of treatment options for COVID-19 that is helpful for the therapy selection and the development of further guidelines and recommendations. |
| 32870117 | None of the surgical providers involved in tracheotomy for patients with COVID-19 demonstrated positive antibody seroconversion or developed SARS-CoV-2-related symptoms to date. |
| 32870407 | To date, no therapy has demonstrated efficacy in COVID-19. |
| 32870512 | An up-to-date understanding of how best to target this therapy (e.g. arterial partial pressure of oxygen (PaO2) or peripheral oxygen saturation (SpO2) aim) in these patients is urgently required. |
| 32870721 | To address this, programs should consider hosting informal virtual gatherings, create videos that highlight the resident experience, and ensure that program websites are up-to-date. |
| 32871864 | Electronic databases of PubMed, MEDLINE, Google Scholar, Web of science, Cochrane Library, EMBASE, CNKI, CMB, and Wangfang database from the inception to present will be comprehensively and systematically searched without limitations of language, date, and publication status. |
| 32871977 | This systematic review findings will summarize up-to-date evidence for that CM is more effective and safe as adjunctive treatment for patients with COVID-19. |
| 32872017 | Two independent reviewers will search the following databases of the China Biology Medicine disc, China National Knowledge Infrastructure, China Science and Technology Periodical Database, Wanfang database, Embase, PubMed, and Cochrane Library from the date of conception to June 1, 2020. |
| 32872048 | Two independent reviewers searches the databases of the China Biology Medicine disc, China National Knowledge Infrastructure, China Science and Technology Periodical Database, Wanfang Database, PubMed, Embase, and Web of Science from the date of conception to June 30, 2020. |
| 32872736 | We performed a case-control study that utilized up-to-date data on the South Korean population provided by the Korean National Health Insurance System. |
| 32873235 | To date, few studies have investigated bacterial superinfections in COVID-19 patients. |
| 32873480 | To date, it includes viral conjunctivitis, immune conjunctivitis, and oculomotor palsies (OCP) due to the novel coronavirus. |
| 32873575 | Updates may occur for up to two years from the date of original publication. |
| 32873583 | The median date of NPI implementation in Canada was Mar. |
| 32874038 | Moreover, there have been no reported cases of SARS-CoV-2 transmission through tonometry to date. |
| 32874430 | Since it was a discovery, COVID-19 has spread to several countries and to this date, affecting about 2,329,651 people and caused about 160,721 deaths. |
| 32874585 | To date, little is known on the impact of the pandemic on this population, particularly within the UK. |
| 32874663 | We profiled the first 147 cases referring to sex, age, place of residence, probable country of infection, return day to Romania, COVID-19 confirmation date and the probable modes of COVID-19 transmissions. |
| 32874698 | According to the Ministry of Health and population of The Government of Nepal, as of June 20, 2020, out of a total of 8,605 laboratory confirmed cases reported to date, the pattern shows that most of the cases fell into the cohort of 21-30 years (37.72%), followed by 11-20 years (24.35 %), 31-40 years (21.97%) and 41-50 years (9.2%). […] To date Nepal has recorded a total of twenty-two deaths. |
| 32874745 | Several studies to date have suggested worse outcomes occur in patients with elevated troponin levels. […] Additionally, there have been concerns raised regarding COVID-19-related myocarditis, of which reported biopsy-proven cases to date appear to be rare. |
| 32874851 | COVID-19 posed a major public health threat on China with a cumulative number of cases over 89,000 (data cut-off date: August 9th, 2020). |
| 32874863 | The analysis on the excess deaths also shows that the impact in deaths is far higher than the official numbers reported to date for some countries. |
| 32874996 | From the enactment of COVID-19 mitigation policies to the date of survey completion, 90.1% of fellows had performed fewer than 20 cases. […] Also, 10 respondents’ intended practice start date was being delayed by their employer. |
| 32875276 | To date, there are about 18.8 million infected people and about 700,000 deaths. |
| 32875494 | In the largest study of SNFs to date, SARS-CoV-2 infections were detected among both employees and residents. |
| 32875509 | Public health messaging to date may not be effectively reaching vulnerable communities. |
| 32875950 | To the best of our knowledge, till date only one compound has been identified and tested in-vitro as a potent inhibitor of 3CLpro protein, addressed as N3 (PubChem Compound CID: 6323191) and is known to bind irreversibly to 3CLpro suppressing its activity. |
| 32876275 | No filters related to date, language or publication status were applied. |
| 32876277 | To date, several scientific publications have revealed a concentration of up to 60% of deaths attributed to COVID-19 in such institutions. |
| 32876296 | In particular, from February 26, 2020 (date of the first COVID-19 case reported in Brazil) until June 18, 2020, Brazil reported 124 maternal deaths. |
| 32876623 | To date, Remdesivir has been the only antiviral authorized by FDA as therapy for emergency use. |
| 32876694 | The trials were conducted in 12 countries from February 26, 2020, to June 9, 2020, and the date of final follow-up was July 6, 2020. |
| 32877383 | To date, no information is available on the risk of contagion from the peritoneal fluid with which surgeons can come into contact during the abdominal surgery on COVID-19 patients. |
| 32877391 | To date, more than seventeen million confirmed cases and more than half a million died worldwide from COVID-19. |
| 32877395 | To date, some scientific publications provide initial evidence that SARS-CoV-2 can be detected in the air, thus assuming a further route of infection, that airborne, although these results are to be considered preliminary and they need careful interpretation. |
| 32877867 | Although some studies have already been undertaken into the subject of health-focused inequality in the cities of developing countries, the spatial inequity in hospital accessibility has rarely been discussed to date. |
| 32877985 | To date, there has been relatively little published research on the mental health impacts of COVID-19 for the general public at the beginning of the U.S.’ experience of the pandemic, or the factors associated with stress, anxiety, depression, and post-traumatic growth during this time. |
| 32878480 | To date, no study has examined whether an increased fraction of inspired oxygen (FiO2) may affect the expression of SARS-CoV-2 entry receptors and co-receptors, including ACE2 and the transmembrane serine proteases TMPRSS1, TMPRSS2, and TMPRSS11D. |
| 32878619 | There was a visible difference by discharge status, with patients who were discharged alive having longer LoS than those who died during their admission, but no trend associated with study date. |
| 32878641 | To date, August 30, 2020, no effective, proven therapeutic antibodies or specific drugs, and vaccines have turned up. |
| 32879801 | Experts suggest that almost everyone in China is susceptible to SARS-CoV-2 infection, and to date, there are no effective treatments. |
| 32880078 | As society is running against the time to combat the COVID-19, we present here a comprehensive review dealing with up-to-date information of therapeutics or drug regimens being utilized by physicians to treat COVID-19 patients along with in-depth discussion of mechanism of action of these drugs and their targets. |
| 32880263 | However, much of the local debate to date has centred on questions surrounding whether regulatory approval processes are limiting access to serological tests, and has not paused to consider the intrinsically limiting impact of underlying fundamental biology and immunology on where and how different COVID-19 serological tests can usefully be deployed in the response to the current pandemic. |
| 32880407 | Accurate, up-to-date data are the bedrock of effective public health responses, including in the context of the suffering caused by COVID-19. |
| 32880635 | Despite this, there has been little research to date on the relationship between loneliness and COVID-19 preventive behaviours. |
| 32880651 | Treatment changes were defined by changes in vitamin D type and dose between the date of the last vitamin D level measurement and the date of COVID-19 testing. |
| 32881007 | This review was conducted to evaluate the impact of glucocorticoid therapy in patients with COVID-19 based on the publications reported to date. |
| 32881055 | However infections in neonates are higher than in older children, according to the largest population-based study to date, and this means that infants may also face a higher risk of severe respiratory failure (1). |
| 32881976 | To date, most studies have focused on the effect of COVID-19 on kidney function, whereas data regarding kidney function on the COVID-19 prognosis is scarce. |
| 32882184 | To date, reports have identified 5main categories: acral lesions, vesicular rashes, urticarial rashes, maculopapular rashes, and livedoid and necrotic lesions. |
| 32882393 | We included all adult human studies (>20 subjects) regardless of language, region or publication date or status. |
| 32882434 | Each analysis was performed using two different calculations of CFR: according to the calendar date and according to the days since the outbreak of the first confirmed case. […] We thus explored an innovative and original calculation of CFR, concurrently based on the date of the first confirmed case as well as on a daily basis. […] For the first time, we showed that using meta-analyses according to the calendar date and days since the outbreak of the first confirmed case, were different. |
| 32884603 | While only a few in vitro studies have pointed to some efficacy of these drugs as a prophylactic against COVID-19, to date, there are no clinical studies that have established any clinical efficacy of these drugs as a prophylactic. |
| 32885278 | Whereas anesthesiologists may be primarily concerned with airway and respiratory management, the COVID-19 data accumulated to date indicate that primary and/or secondary cardiovascular complications are common. |
| 32886249 | Demographic data, comorbidities, ASA grade and date of death (if applicable) were collected. |
| 32888676 | All personnel in charge of colorectal surgery units nationwide received a survey (from February to April, 2020) with eight questions divided into three sections-cessation date of colorectal cancer surgeries, number of patients waiting for treatment, and use of neoadjuvant therapy to postpone surgery. |
| 32890139 | To date, there are no studies that compared the disease severity of COVID-19 in SOT recipients with nontransplant patients. |
| 32890343 | There is perception that this phenomenon has involved also surgical emergency, but no extensive data have been presented to date. |
| 32890353 | The COVID-19 epidemic has been a major global public health problem during past months in Italy and in several other Countries and on the date of publication of this article, is still a serious public health problem. |
| 32890356 | The aim of this paper is to enhance the importance of providing up to date informations about nicotine and tobacco use in connection with the SARS-CoV-2-related conditions. |
| 32890371 | In the case of a convergent inversion a mid-callosal clash will result, which is observable in psychoses as a mid-callosal high-flow-spot simultaneously with hyper-perfusions of branches and “backwatering” of pial vessels with reactive waste - till date interpreted psycho-mathematically. |
| 32890516 | Telehealth initiatives have been started in 64.3% of facilities to date for on-treatment (29.6%) and posttreatment (34.8%) patients. |
| 32891160 | The intended completion date is 15th January 2021. […] Date of trial registration: 11 May 2020. |
| 32892500 | In many countries, the pandemic had experienced two waves to date. |
| 32893532 | To date, infection control measures for COVID-19 have been focusing on the involvement of the respiratory system. |
| 32894436 | To date in Ireland, over 3300 patients have been admitted to acute hospitals as a result of infection with COVID-19. |
| 32894621 | Lung ultrasound has become an important tool in diagnosis and follow-up of patient with COVID-19 infection.Here we review available, up to date literature on ultrasound use for COVID-19 suspected pediatric patients and contrast it to published findings in adult patients. |
| 32894641 | To date, no recipients have developed posttransplant COVID-19. |
| 32894747 | In this viewpoint, we highlight evidence regarding the increased potential of AYA to transmit SARS-CoV-2 that, to date, has received little attention, discuss adolescent and young adult specific considerations for future COVID-19 control measures, and provide applied programmatic suggestions. |
| 32894838 | To date, there have been few reports of kidney biopsy findings in the context of AKI in COVID-19 infection. |
| 32895056 | The date of approval is 18th June 2020. |
| 32895596 | These findings add an important perspective to the emerging literature on the efficacy of shelter-in-place orders, which to date is dominated by studies of the United States. |
| 32895747 | Physicians face the challenging task of keeping up with the most up-to-date information on COVID-19. |
| 32895900 | To date, most MSC-based preclinical and clinical trials targeted immune-mediated and inflammatory diseases. |
| 32896226 | Till date, there is no vaccination or drugs been approved for the treatment by the World Health Organisation. |
| 32897389 | The reported SARS-CoV-2 Simoa antigen assay is the first to detect viral antigens in the plasma of COVID-19 positive patients to date. |
| 32898149 | NSAID users (defined as individuals having filled a prescription for NSAIDs up to 30 days before the SARS-CoV-2 test) were matched to up to 4 non-users on calendar week of the test date and propensity scores based on age, sex, relevant comorbidities, and use of selected prescription drugs. |
| 32901229 | To date, several modes of transmission such as droplet, contact, airborne, blood borne, and fomite have been described as plausible. |
| 32901580 | Neuropsychologists need to understand the potential cognitive and psychological sequelae of COVID-19 and the impact of the interventions (e.g., ICU, ventilation) that have been used in treating patients with severe forms of the illness.Method: We briefly review the literature regarding the neurological and neuropsychological effects of similar coronaviruses, the limited information that has been published to date on COVID-19, and the literature regarding the long-term cognitive and psychological effects of undergoing treatment in the intensive care unit (ICU). |
| 32901696 | Here, we estimate the probable onset date of the community spread of SARS-CoV-2 for heavily affected countries from Western Europe and the Americas on the basis of the cumulative number of deaths reported during the early stage of the epidemic. |
| 32902087 | A literature search in the PubMed and Scopus databases was conducted, till the cut-off date of 24th July 2020, using the following terms: “skin” or “cutaneous” or “urticaria” or “urticarial,” and “COVID-19” or coronavirus disease. |
| 32902338 | To date, research on preferred interpersonal distances suggests that social distancing could induce discomfort, heighten arousal, and decrease social signaling in the short term. |
| 32902940 | To date, there is no valid medication or vaccination. |
| 32903258 | Secondary outcomes were ICU transfer, intubation, in-hospital mortality, discharge, length of stay, and daily trend of SpO2/FiO2 (SF) ratio from the index date. |
| 32903391 | To date, no studies have taken into consideration the possible secondary effect of mechanical ventilation on brain recovery and outcomes. |
| 32904353 | To predict the number of active cases, deaths and recovery, date wise analysis of current data was done and necessary parameters like daily recovery, daily deaths, increase rate of covid-19 cases were included. |
| 32904494 | Most participants (92.2%) identified elderly individuals as one of the high-risk groups for severe complications and death while 89.5% identified supportive therapy and life support as recommended management options to date. |
| 32904707 | In particular, SARS-CoV-2 spread rapidly over the globe affecting nearly 25.000.000 people up to date. |
| 32904875 | Key recommendations specific to the COVID-19 pandemic include providing up-to-date, health literate, concise information about preventing COVID-19 and accessing care including telehealth. |
| 32905064 | In this article, we present new datasets to track the extent to which multilateral financial institutions are meeting these goals, and conduct a preliminary assessment of progress to date. |
| 32905098 | Our analysis shows that with no lockdown around 2.1 million people might get infected during the peak of spread around 2 months from the date the lockdown was first enforced in KSA (March 25th). |
| 32905786 | To date, there is little published data regarding the presentation and severity of illnesses during the coronavirus disease 2019 pandemic. |
| 32906151 | These data are the highest seroprevalence rates observed to date and highlight the significant burden of asymptomatic infection. |
| 32907635 | Protocol version 3.0, 18 May 2020 Recruiting start date: June 2020. |
| 32907638 | Duration of hospitalisation: Days from the date of enrolment to the date of discharge 3. |
| 32907693 | Between the 31st of December 2019 and the 30th of August 2020 (date of this article), the novel coronavirus and its corresponding infection, COVID-19, more than 25 million cases and 843,158 deaths have been registered. |
| 32909171 | This comprehensive review aimed to: identify all up-to-date original publications relating to urology and COVID-19, characterise where publications were from, and outline what topics were investigated. |
| 32909890 | Her symptoms and pericardial effusion resolved, and she was discharged to home 3 days later on ibuprofen and colchicine with instruction to quarantine at home for 14 days from the date of her positive testing for COVID-19. |
| 32910251 | To our knowledge, cases of spinal epidural abscess in COVID-19 patients have not been reported to date. |
| 32910604 | To date, we have limited information on the operations performed on these patients. |
| 32912089 | COVID-19 has to date affected over 5 million people worldwide and caused in excess of 300000 deaths. |
| 32912356 | The older population is the most vulnerable to serious complications from this illness and over 90% of deaths due to COVID-19 to date have been in patients over the age of 65. |
| 32915172 | To date, there is a lack of reliable study data on the care for patients with complex respiratory, atopic, and allergic diseases in times of an imminent infection risk from SARS-CoV-2. |
| 32915657 | One approach organizations may take to tackle this involves issuing raw data publicly for collaboration with other organizations in order to spark discussion, collectively experiment and stay up to date with advances in scientific knowledge. |
| 32916509 | To date, maximal precautions to prevent coronavirus infection should be maintained in MS/NMOSD patients already exposed to COVID-19 during anti-CD20 therapy. |
| 32917259 | The date of approval is 14th April 2020. |
| 32918792 | In the absence of mechanical ventilation, the timing of the dose was related to the patient’s date of admission only. |
| 32920231 | This article outlines the role of African civil society in safeguarding gains registered to date in sexual and reproductive health and the response to HIV. |
| 32920233 | To date, the rapid spread of the newly emerged coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing coronavirus disease 2019 (COVID-19), has affected over 3.8 million people across the globe. |
| 32921700 | Cases were classified as transmitted before or after the decree according to the date of last contact with a COVID-19 case or, if this date was unavailable, we used the date of onset of symptoms considering the incubation period. |
| 32921705 | The mortality rate of COVID-19 was 4.71% in the normal Iranian population compared to 18.6% in β-thalassemias (P: <0.001) at the same date. |
| 32921707 | Because of this rapid increase in infected people scientists wonder whether SARS-CoV-2 was already highly circulating in Lombardy before such date. |
| 32921710 | A digital search was performed in Medline and Web of Science, using the keywords “coronavirus disease 2019” OR “COVID-19” OR “severe acute respiratory disease 2” OR “SARS-CoV-2” AND “recurrence” OR “repositivization” OR “retesting”, without date or language restrictions. |
| 32921717 | To date, more than 9,000 academic papers have been published since December 2019. |
| 32921732 | To date, it is only clear that no drug can alone cope with all the problems posed by SARS-CoV-2 infection and effective antivirals and inflammatory drugs must be given together to reduce COVID-19 clinical manifestations. |
| 32921865 | The association between COVID-19 cases and climate indicators in London, UK were analysed statistically employing published data from national health services, UK and Time and Date AS based weather data. |
| 32922769 | Till date, no definite treatment for COVID-19 has been discovered. |
| 32923299 | Lumbar spine and femur proximal bone mineral density (BMD) were measured at the last follow-up date (May 25 to June 30, 2020; 0M) and six (6M) and 12 months (12M) before the last follow-up using dual-energy X-ray absorptiometry. |
| 32923450 | To date, there is no specific anti-SARS-CoV-2 drug. |
| 32923601 | We relate this reduction to two of the government’s actions: the announcement of the first report in each province and the date of a province’s lockdown. |
| 32924650 | Limits were put on date to obtain articles between December 2019 to May 2020 (the time at which the search was performed). 776 articles were identified and screened. |
| 32924707 | Retrospective, single-center case series of the 66 hemodialysis patients with confirmed COVID-19 from 1 January to 5 March 2020; the final date of follow-up was 25 March 2020. |
| 32924965 | After finding the first positive cases, the question arose whether the virus had entered Hungary and caused infections before this date. |
| 32925114 | To date there is no clear evidence of vertical transmission of the virus before birth. |
| 32926160 | Yet, to date, there are no longitudinal studies that examined whether the pandemic affects PA levels and what factors help people remain physically active during lockdown. |
| 32926171 | With over 9,000 completed surveys from every US state and over 70 countries worldwide, to our knowledge this is the largest pandemic messaging study to date. |
| 32926211 | Studies published to date have also reported abdominal imaging findings including small and large bowel wall thickening, fluid-filled colon, pneumatosis intestinalis, pneumoperitoneum, intussusception, and ascites. |
| 32927628 | However, to date, children, especially neonates, have been relatively spared from the devastating consequences of this infection. |
| 32929403 | To date, clinical outcomes appear reassuring, but data related to important long-term outcomes are missing or not yet reported. |
| 32930523 | More than ten million patients worldwide have been diagnosed with coronavirus disease 19 (COVID-19) to date (WHO situation report, 1st July 2020). |
| 32932582 | To date, no information is available about care dependency. |
| 32932612 | To date, only hypotheses have been raised to explain this difference, so it is of great importance to describe the presentation of this disease among children. |
| 32932930 | Few publications to date describe using these drugs in COVID-19. |
| 32933552 | The registration date is 31 May 2020. |
| 32934635 | Since the COVID-19 outbreak is up to date existed, therefore this report is considered as interim guidelines for airway management of the suspected/confirmed patients. |
| 32935873 | Neuropathological examination of brain tissue at autopsy will be essential to establish the neuro-invasive potential of the SARS-CoV-2 virus but, to date, there have been few detailed studies. |
| 32936466 | Although in 2016 the GPEI expected to globally coordinate cessation of the remaining OPV serotypes (1 and 3) by 2021, continuing transmission of serotype 1 wild polioviruses to date makes those plans obsolete. |
| 32936947 | The date of the search was 1 June 2020. |
| 32936948 | The date of the search was 1 June 2020. |
| 32936949 | The date of the search was 1 June 2020. |
| 32938496 | Protocol Code: SARTRE Protocol Date: May 05th 2020. […] Start of recruitment: August, 2020 End of recruitment: May, 2021 TRIAL REGISTRATION: Identifier: EudraCT Number: 2020-002037-15 ; Registration date: 26 May 2020. |
| 32938901 | MATERIAL AND METHODS A total of 243 patients with STEMI who underwent PCI were consecutively enrolled and divided into 2 groups according to the date, before or after the pandemic. |
| 32938937 | To date, there is no treatment for coronavirus infections, making the development of therapies to prevent future epidemics of paramount importance. |
| 32939911 | To date, there are no reports on Magnetic Resonance Imaging (MRI) findings in patients with persistent anosmia or hyposmia due to COVID-19. |
| 32940705 | The CDC COVID-19 Information Management Repository was created to address the need for PH and health-care stakeholders at local and national levels to easily obtain access to comprehensive and up-to-date information management resources. |
| 32941066 | The main exposure was survey completion date (March 10-16, 2020). |
| 32941252 | To date, nearly 80,000 users from 132 countries have accessed the curriculum. […] As understanding of the COVID-19 pandemic is constantly changing, the student authors’ immediate goal is to keep the curriculum up to date in the months to come. |
| 32941461 | The further the onset of symptoms was from the date of collection, the greater the sensitivity. […] The sensitivity of COVID-PRESTO® test ranged from 10.00% for patients having experienced their 1st symptoms from 0 to 5 days ago to 100% in patients where symptoms had occurred more than 15 days before the date of tests. |
| 32942705 | To date, there are limited reports describing differences in clinical, laboratory, and radiological characteristics between asymptomatic and symptomatic infection, and between younger and older pediatric patients. |
| 32942796 | To date, there has been no review of all the clinical trials that have assessed the safety and efficacy of MSC therapy in organ failure commonly seen in seriously complicated COVID-19 patients. |
| 32943228 | To date, there are limited data available on the analytical performance of emerging commercially available assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and integration of these assays into laboratory workflows. |
| 32943287 | To date, little evidence is available about the effect of lockdown release in terms of adolescent health from the perspective of an emergency department (ED). |
| 32943630 | Given the limited availability of serological testing to date, the seroprevalence of SARS-CoV-2-specific antibodies in different populations has remained unclear. |
| 32943888 | To date, no specific vaccine or drug has been proven to be effective against SARS-CoV-2 infection. |
| 32944292 | Coronavirus disease 2019 (COVID-19) is a debilitating viral infection and, to date, 628,903 people have died from it, numbers that cannot yet be compared to the 50 million who died in the 1918 flu pandemic. |
| 32945643 | Novel coronavirus disease (COVID-19) has affected nearly 7 million individuals and claimed more than 0.4 million lives to date. |
| 32945710 | The prescription was not documented in the oxygen section of the drug chart (n = 37, 56.1%, p = 0.389), nor did it have the physicians signature (n = 40, 60.6%, p = 0.110) nor date (n = 46, 69.7%, p = 0.002). |
| 32945766 | The regression model also included vectors of fixed effects for the day of the week, the calendar date, and the zip code of residence. |
| 32946270 | Conclusions The existing literature on cognitive sequela of COVID-19 infection is small to date, but much can be learned from similar viral infections and disorders. |
| 32947121 | To date, the published data has analyzed the seroprevalence of COVID-19 infection in the general population, but not in cancer patients. |
| 32947927 | Several promising therapeutics are under investigation to the overall prognosis of COVID-19 patients with high risk of cardiovascular impairment, nevertheless to date, none have shown proven clinical efficacy. |
| 32948577 | We classified trials according to intervention type, and report key trial characteristics including recruitment status, location, funder type, target enrolment number, intervention model (single group, randomised or sequential assignment) and projected completion date. |
| 32948856 | Relative to these indicators, SARS-CoV-2 RNA concentrations in sludge were 0-2 d ahead of SARS-CoV-2 positive test results by date of specimen collection, 0-2 d ahead of the percentage of positive tests by date of specimen collection, 1-4 d ahead of local hospital admissions and 6-8 d ahead of SARS-CoV-2 positive test results by reporting date. |
| 32949606 | Up to date, they are tested for a number of other disorders including the broad spectrum of viruses. |
| 32952250 | However, to date, researchers have not considered how demographics and personality could interact to influence COVID-19 coping responses. |
| 32952300 | The limit of detection (LOD) of the clinical specimen was 200 copies/mL, which is the lowest LOD among the published RNA measurement of SARS-CoV-2 to date. |
| 32952823 | To date, 42 African countries imposed lockdowns on movements and activities. |
| 32952854 | To date, COVID-19 infection has led to about 165000 deaths in 150 countries. |
| 32952855 | To date, several clinical trials have been registered to assess the safety, efficacy, and therapeutic potential of MSCs in COVID-19. |
| 32954247 | To date, there have been no published review of therapeutics in the pregnant patient infected with SARS-CoV-2. |
| 32956164 | Some digital tools have been used as components of SUD research in the past; however, no published clinical trial in SUDs to-date has been entirely virtual. |
| 32956550 | To date, there is limited evidence that these informal healthcare providers receive support from community-based nurses. |
| 32957036 | Survivors of critical illness and ARDS often experience neurocognitive impairment but, to date, there is scant literature correlating radiographic hypoxic brain injury to hypoxemia related to ARDS. |
| 32957894 | Vaccines and antiviral medications are still under trial to prevent or treat infections of human coronavirus (HCoV) till date. |
| 32958069 | To date, only a few neonatal early-onset sepsis by SARS-COV-2 has been reported worldwide. |
| 32959032 | When applied to the COVID-19 Open Research Dataset (CORD-19), dimensionality reduction suggests that COVID-19 studies to date are primarily clinical-, modeling- or field-based, in contrast to the vast quantity of laboratory-driven research for other (non-COVID-19) coronavirus diseases. |
| 32959455 | Finally, we discuss emerging evidence supporting the reduction in mortality in patients with COVID-19 with the use of corticosteroids, while tabulating up-to-date information on the safety of various investigational therapies for COVID-19. |
| 32959547 | The final follow-up date was May 19, 2020. |
| 32960646 | To date, there are no scientific papers offering disease and/or recovery profiling for patients with dysphagia and coronavirus disease 2019. |
| 32960938 | During the outbreak of COVID-19 and up to the present date, there have been no confirmed cases of COVID-19 in this hospital thanks to strict protocols for infection prevention and control. |
| 32961082 | No vaccine against any human coronavirus is available to date. |
| 32962613 | The article highlights an up-to-date progress in studies of structure and the remedial aspects of novel coronavirus 2019-nCoV, renamed as SARS-CoV-2, leading to the disease COVID-19, a pandemic. |
| 32962623 | To date, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected millions of individuals around the world. |
| 32963441 | This description is up to date as of now, but as more experiences are pouring from different corners of the world, almost every day, newer knowledge and information will crop up by the time this article is published. |
| 32963819 | Several treatment strategies are currently under investigation for COVID-19, but none of them have been proved to be safe and effective to date. |
| 32964098 | Coronavirus Disease 2019 continues to spread and to date, no definitive treatment is available. |
| 32964657 | A total of 81 polymerase chain reaction (PCR)-confirmed COVID-19 positive subjects, of whom 54 self-reported smell loss, were prospectively recruited ≤5 days from diagnosis date between May 8, 2020, and July 8, 2020. |
| 32965017 | The information on daily temperature and humidity was obtained from world climate web “Time and Date”. […] The daily cases, deaths, temperature and humidity were recorded from the date of appearance of first case of “Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)” in the European region, from Jan 27, 2020 to July 17, 2020. |
| 32965378 | The implementation’s timing considered both the chronological date and the epidemiological timing, based on the time since the 10th case or 1st death from COVID-19 in each state. |
| 32966809 | The reader should take advantage of the most up-to-date information when making clinical decisions. |
| 32967005 | Here we summarize the findings to date and provides relevant information for preclinical testing of vaccine candidates and therapeutic agents for COVID-19. |
| 32967179 | To date, there is no specific medicine or vaccine available against this pandemic disease. |
| 32967466 | However, to date, only a few data are available on the impact of COVID-19 pandemic on ophthalmological care in different health care systems, its future consequences in terms of disability, and access to sight-saving cures for many patients. |
| 32967538 | Data from available research were used to estimate parameters for the calculation of population attributable risk for COVID-19 deaths reported to date. […] Assuming Trump’s pronouncement to have caused 25%, 50%, and 75% of the non-use of masks, estimates of Trump-attributable COVID-19 deaths to date would be, respectively, 4,244, 8,356, or 12,202. |
| 32969125 | To date there are no randomised trial data on its use in any novel coronavirus infection, although a large number of trials are currently in progress. |
| 32969846 | The expected number (predicted period) was assumed based on the linear trend of trauma activations seen in the prior 3 years (2017 to 2019) for the same date range (March 20, 2020 to May 14, 2020). |
| 32969952 | Mobility exposure: indicator of order enactment by March 29, 2020 (date of mobility data collection). |
| 32970560 | To help equip frontline emergency clinicians with up-to-date protocols throughout the evolving COVID-19 crisis, our team set out to create a dynamic digital tool that centralized and standardized resources from a broad range of platforms across our hospital. |
| 32970655 | The COVID-19-Associated Hospitalization Surveillance Network (COVID-NET) (3) collects data on hospitalized pregnant women with laboratory-confirmed SARS-CoV-2, the virus that causes COVID-19; to date, such data have been limited. |
| 32970935 | This review gathers the available evidence on the global spread of CoVs in wild birds to date. |
| 32972300 | Furthermore, compounding these concerns is the inadequate supply of personal protective equipment, decreased hospital capacity, and paucity of effective treatments or vaccines to date for COVID-19. |
| 32972778 | In this article, we describe the mental health outcomes known to date in regard to the novel coronavirus disease 2019 pandemic for obstetric patients and their providers as well as therapeutic approaches, including our novel embedded mental health service, to address these mental health needs. |
| 32972861 | Studies to date support the safety-and increasingly the efficacy-of CCP to treat COVID-19. |
| 32973066 | To monitor the spreading of COVID-19 in Italy from February 24th to March 13th (the date of the Italian lockdown), official daily data for PM10 levels were collected from all Italian provinces between February 9th and February 29th, taking into account the maximum lag period (14 days) between the infection and diagnosis. |
| 32973526 | To date no specific antiviral drug have been approved for COVID-19, so the treatment of the disease is mainly focused on symptomatic treatment and supportive care. |
| 32974019 | We have outlined the common neurological manifestations in COVID-19 (information are up-to-date as of June 2020) and discussed the possible pathogenetic mechanisms and management options. |
| 32974268 | To date, no vaccine or definitive treatment is available to defeat the virus and therapies are mainly based on existing drugs used to treat other conditions. |
| 32974860 | Drawing on a health and human rights framework, this commentary explores several features of the Canadian response to date that raise human rights concerns. |
| 32975182 | These results suggest that a larger number of people have been infected than the counts detected by surveillance to date; nevertheless, the results suggest the large majority of the general population in Addis Ababa currently is susceptible to COVID-19. |
| 32977074 | The extent of the impact of COVID-19 has not been well characterized in large samples of PwMS to date. |
| 32977525 | The purpose of this review paper is to summarize the main approaches developed to date in the chemical and photodynamic inactivation of human and animal viruses using porphyrins and their analogues and to analyze and discuss the information on viral targets and antiviral activity of porphyrins, chlorins, of their conjugates with organic/inorganic compounds obtained in the last 10-15 years in order to identify the most promising areas. |
| 32978111 | In order to understand more fully the challenges and successes of technology-enabled care to date, a national survey of practice across hand units in the UK was conducted. |
| 32978207 | Retrospective cohort study of 516 patients consecutively admitted for COVID-19 to two Italian tertiary hospitals located in Northern and Central Italy were collected from 22 February 2020 (date of first admission) to 10 April 2020. |
| 32978313 | To date, there are no U.S. […] To date, there are no approved prophylactics or therapeutics available for COVID-19. |
| 32978339 | The COVID-19 pandemic has had variable impacts in the WHO South-East Asia Region to date, but in the countries most affected there has been targeted diversion and repurposing of tuberculosis services, health-care workers and diagnostic equipment. |
| 32978344 | Effective communication of essential, accurate and up-to-date information regarding COVID-19 prevention and control is essential in this population - especially for men, older age groups and those lacking formal education. |
| 32978347 | To date, application of the three-step analysis to data from countries of the region has signalled potential inadequacies of testing strategies. |
| 32978702 | The data lock point date was 7 June 2020. |
| 32979305 | To date, research on the indirect impact of the COVID-19 pandemic on the health of the population and the health-care system is scarce. |
| 32979667 | To date, in vivo effectiveness of PVP-I against SARS-CoV-2 has yet to be established and possible risks of its direct use on upper aerodigestive mucosa of children must be weighed. |
| 32979987 | The index date (start of follow-up) for both cohorts was March 1, 2020; follow-up lasted until May 6, 2020. […] For the COPD cohort, individuals were eligible if they were aged 35 years or older, had COPD, were a current or former smoker, and were prescribed an ICS or long-acting β agonist plus long-acting muscarinic antagonist (LABA-LAMA) as combination therapy within the 4 months before the index date. […] For the asthma cohort, individuals were eligible if they were aged 18 years or older, had been diagnosed with asthma within 3 years of the index date, and were prescribed an ICS or short-acting β agonist (SABA) only within the 4 months before the index date. […] We identified 148 557 people with COPD and 818 490 people with asthma who were given relevant respiratory medications in the 4 months before the index date. |
| 32981492 | In Victoria, 97% of cases (621) were locally acquired and were mostly reported from residential aged care facilities; and 3% of cases (19) were reported as under investigation at the date of extract this reporting period. |
| 32981871 | All OMFS programs (100%) implemented guidelines to suspend elective and nonurgent surgical procedures and limited ambulatory clinic visits by third week of March, with the average date being March 16, 2020 (date range March 8-23). |
| 32981876 | To date, there are no specific guidelines to optimize telemedicine encounters in oral and maxillofacial surgery. |
| 32982078 | Based on our projection results, the probable peak date is estimated to be on August 1, 2020 with approximately 1073 (95 % C I : 714 - 1654) daily confirmed cases. |
| 32982082 | To date, there is no definite answer about whether people who recover from COVID-19 can be reinfected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). |
| 32982514 | Since the new measures were implemented, to date there have only been three new confirmed cases of COVID-19 infection, no cases of medical staff infection, and no COVID-19-related deaths at the hospital. |
| 32982616 | Although previous outbreaks of human coronaviruses (CoVs) such as SARS and MERS stimulated research, there are, to date, no antiviral therapeutics available that specifically target these kinds of viruses. |
| 32983694 | Data were also stratified by date and comparison was made between the intra-COVID-period (March and April 2020), pre-COVID period (March and April 2019), and peri-COVID period (January and February 2020). |
| 32984764 | A systematic review was done to analyze the clinical profile and outcomes in a total of 45 cases of new-onset ITP in COVID-19 patients described in literature until date. |
| 32984766 | To date, many medical schools have successfully transitioned their educational environment to emergency remote teaching and assessments. |
| 32984987 | To date, COVID-19 had spread to almost 235 countries and territories due to its highly infectious nature. |
| 32985046 | To date, no studies have been conducted examining how this fear of COVID-19 contributes to health, well-being and work outcomes in frontline nurses. |
| 32986137 | To date the severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2), known as COVID-19, is for clinicians the most difficult global therapeutic problem. |
| 32986989 | Uninfected pregnant women (controls) were matched to coronavirus disease 2019 cases on a 2:1 ratio based on delivery date. |
| 32987008 | However, initial reports of ECMO use in patients with COVID-19 described very high mortality and there have been no large, international cohort studies of ECMO for COVID-19 reported to date. |
| 32987103 | To date, the pandemic of COVID-19 causes 11.8 million cases and about 545481 deaths in the world. |
| 32987167 | Novel coronavirus disease-19 (COVID-19) has spread worldwide, and to date presence of the virus has been recorded in 215 countries contributing 0.43 million of death. |
| 32987177 | Absolute numbers of COVID-19 cases and deaths reported to date in the sub-Saharan Africa (SSA) region have been significantly lower than those across the Americas, Asia, and Europe. |
| 32987551 | Our findings suggest that if the lock-down date in Wuhan is earlier, the infectious cases are fewer. […] Moreover, we reveal the effects of city lock-down date on the final scale of cases: if the date is advanced two days, the cases may decrease one half (67, 95% CI: 66-68); if the date is delayed for two days, the cases may reach about 196 (95% CI: 193-199). |
| 32988772 | In this review, the authors discuss up-to-date advances in immune-based therapy for COVID-19. |
| 32991223 | A seamless Phase I/II design has been applied in multiple COVID-19 vaccine studies to date. |
| 32991879 | To date, COVID-19 has caused about 935,000 deaths in more than 200 countries. |
| 32992359 | The present comprehensive review aims to show the full extent of what is known to date and provide a more thorough view on the effects of SARS-CoV2 in pregnancy. |
| 32993013 | To date, no study has evaluated the impact of Covid-19 on safety culture. |
| 32993173 | Overall, we aim at presenting up-to-date details of anti-COVID-19 therapeutics so as to catalyze their potential effective use in fighting the pandemic. |
| 32993921 | Analysis was performed between two groups, Group A: patients presenting prior to the national lockdown date; and Group B: patients presenting after the national lockdown date. |
| 32994047 | The COVID-19 pandemic in Cuba was addressed through an integrated all-society action plan that to date has been largely successful with a low incidence of COVID-19 and mortality rates several-fold lower than worldwide averages. |
| 32994757 | Up to date, more than one hundred natural PIAs, while only nine natural PQAs had been described. |
| 32995051 | To date, several thousand HWs globally have been reported as infected with the severe acute respiratory syndrome coronavirus 2 virus that causes the disease. |
| 32995681 | The proposed model was enforced to obtain estimates of important quantities such as the reproductive rate and the average infection period, along with the more likely date when the pandemic peak may occur. |
| 32995682 | By the use of a SEIRD mathematical model with age division, we predict the infection and death curves, stating the peak date for Brazil and above states. |
| 32997344 | To date, the coronavirus disease 2019 (COVID-19) has a worldwide distribution. |
| 32997370 | To date it remains unclear whether hyperCKemia is due to a virus-triggered inflammatory response or direct muscle toxicity. |
| 32997373 | The participants were divided into three successive temporal groups based on their date of CT examination. |
| 32997699 | As a result of the influx of clinical trials, researchers, clinicians, and the lay public, now more than ever, face a significant challenge in keeping up-to-date with the rapid rate of discoveries and advances. […] The freely available, novel resources present up-to-date relevant biological information and insights in a robust, accessible manner, illustrating their invaluable potential to aid researchers overcome COVID-19 and save hundreds of thousands of lives. |
| 32997739 | To date, there is little data on possible IgA-mediated autoimmune responses. |
| 32997812 | To date, however, the utility of such immunoassays remains unclear. |
| 32998162 | Unfortunately, data on SARS-CoV-2 viral presence in oocytes of infected individuals are not available to date. |
| 32998992 | The search yielded 2504 citations published between January and February 2020 or an unspecified date, 109 of which remained for extraction after screening. |
| 33000592 | With these goals, the themes presented in this “mosaic” of topics include - Cardiovascular involvement in genetic syndromes, SIDS and infectious, endocrine, kidney, storage or autoimmune diseases. - Pulmonary hypertension and patent ductus arteriosus in premature infants. - Cardiovascular risk in obese or hypertensive children. - Bicupid aortic valve and aortic dysfunction - Covid 19 and heart disease in childhood I thank the Researchers and Professors of Catanzaro, Palermo, Pavia, Brescia, Taormina and Messina University for their interesting and up-to-date scientific contributions, and I hope the information gathered in this issue will be useful to the reader. |
| 33000640 | To date, this process has avoided the worst-case scenario of intra-hospital epidemic outbreak. |
| 33001783 | To date, only a few articles have been published that comprehensively describe the multisystemic imaging manifestations of COVID-19. |
| 33002041 | To date, several clinical laboratory parameters associated with Coronavirus disease 2019 (COVID-19) severity have been reported. |
| 33002611 | Up-to-date trials were identified by the authors through searches of Medline, Embase, Cochrane Library, Web of Science, ClinicalTrial.gov, and medRxiv from inception up to 14 September 2020. |
| 33003471 | To date, sporadic studies have demonstrated that innate immune mechanisms, specifically neutrophilia, NETosis, and neutrophil-associated cytokine responses, are involved in COVID-19 pathogenesis; however, our understanding of the exact nature of this aspect of host-pathogen interaction is limited. |
| 33003648 | The highly contagious COVID-19 infection has affected millions of people to date and has led to hundreds of thousands of deaths worldwide. |
| 33004166 | Based on up-to-date research and psychological diagnostic manuals of Diagnostic and Statistical Manual of Mental Disorders, 5th edition and International Classification of Diseases, 11th revision, we describe associated psychological disorders and experiences that may arise related to COVID-19. |
| 33004545 | To date, 33 papers have been identified as unsuitable for public use and either retracted, withdrawn, or noted with concern. |
| 33004712 | To date, no specific treatments are available for COVID-19 and its life-threatening complication. |
| 33004773 | Three pediatric deaths have been reported in Italy to date. |
| 33005518 | To date, there have been some reports linking severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to widespread tissue injury; however, there have been no reports so far on the effect of the parathyroid gland. |
| 33006163 | A literature search was performed to provide the most up-to-date information on the pathophysiology, coagulopathy, risk of VTE, and prevention and treatment of VTE in patients with COVID-19. |
| 33006169 | The COVID-19 pandemic represents one of the most challenging healthcare scenarios faced to date. |
| 33006936 | In our viewpoint, we aim to present the relative literature to date and outline our ongoing analyses of the highly affected and diverse stroke populations in San Antonio and Austin, Texas, to answer a simple question: where did all our stroke patients go? |
| 33006938 | The system was rapidly developed and is being used on a large scale with more than 65,000 registered patients to date. |
| 33007400 | To date, no anti-viral therapy has proven its efficacy considering randomized trials. |
| 33007742 | However, there are still no vaccines or medications available till date against SARS coronaviruses which is an urgent requirement to control the current pandemic like situations. |
| 33008440 | In this single-center, retrospective observational study, we included all cases with chronic infective wounds that came to our hospital between the full outbreak of the COVID-19 in China (January 23, 2020) and the latest date prior to posting (20 April 2020). |
| 33009736 | We used a data set where each point was an expression not of a single day, but of a longer period of time (date-points method). |
| 33009800 | In the eight weeks prior to relaxation, mean Rt declined by 0.012 units per day (95% CI, -0.013 to -0.012), and 46/51 jurisdictions achieved Rt < 1.0 by the date of relaxation. |
| 33010461 | To date, SARS-CoV-2 (the virus that causes COVID-19) has spread to almost every region of the world, infecting millions and resulting in the deaths of hundreds of thousands of people. |
| 33011225 | To date, there is one study confirming that the infectivity of SARS-CoV-2 in water for people was null based on the absence of cytopathic effect (CPE) in infectivity tests. |
| 33011594 | Since the first report in December 2019, the novel coronavirus (COVID-19) has spread to most parts of the world, with over 21.5 million people infected and nearly 768,000 deaths to date. […] In this article, we present the up-to-date evidence and discussions on sewage-associated transmission of COVID-19, and highlighted the roles of sewage overflow and sewage-contaminated aerosols in two publicized events of community outbreaks. |
| 33012500 | Two groups were created: 6 weeks before (Group A) and 6 weeks after (Group B) the date elective surgeries were postponed in Massachusetts for COVID-19. |
| 33012886 | Guidelines are set within a well-scientific evidence and available recommendations up to date. |
| 33012988 | To date, studies on COVID-19 have consistently shown that pediatric patients generally have relatively milder cytokine release syndrome and lower mortality rates than adults. |
| 33013004 | Against a backdrop of heightened uncertainty, up-to-date and reliable information is more important than ever, both for regulators and this sector. |
| 33014380 | To date, more than 300 clinical trials have been conducted on various antiviral drugs, and immunomodulators are being evaluated at various stages of COVID-19. |
| 33015425 | To date, many models have been proposed which estimate the transmission risk of COVID-19 in terms of time; however, its dependency on space dimensions has been ignored. |
| 33015546 | The most encouraging treatment to date is suggested to be with the help of remdesivir, hydroxychloroquine, and many such repurposed drugs. […] No treatments have been demonstrated as accurate and dependable to date. |
| 33015822 | The daily temperature and humidity figures were obtained from the weather web “Time and Date”. […] The daily cases, deaths, temperature and humidity were recorded from the date of appearance of first case of “Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)” in the African region, from Feb 14 to August 2, 2020. |
| 33015938 | It is to date the only approved antiviral for treating COVID-19. |
| 33017195 | To date, only a limited number of public assessments of local mass vaccination operational capabilities have been conducted. |
| 33017479 | References for this review were identified by searches within PubMed without any date restrictions. |
| 33017611 | To that end, we have examined the scientific literature to date regarding the viability of SARS-CoV-2 on surfaces and fluids or under different environmental conditions (temperature, precipitation and UV radiation). |
| 33019397 | All the above databases will be searched from the available date of inception until the latest issue. |
| 33019921 | Till date, SARS-CoV-2 infection is still spreading, representing a major threat to public health, where several control measures are being practiced in order to culminate its spread. |
| 33019935 | COVID-19 originated in Wuhan, the capital of Hubei, China in December 2019 and, to date, has spread to at least 187 countries. |
| 33020340 | To date, there is still no vaccine or specific antiviral treatment for COVID-19. |
| 33020343 | To date, no specific therapeutic drugs are available to treat COVID-19 infection. |
| 33020695 | Till date more than 0.948 million deaths out of 30.369 million confirmed cases are reported by WHO. |
| 33020707 | To date, neither a specific antiviral drug nor a clinically effective vaccine is available. |
| 33020722 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the recent pandemic COVID-19, is reported to have originated from bats, with its intermediate host unknown to date. |
| 33020732 | To date, qualitative olfactory testing has been performed only in a very few cohort studies on COVID-19 patients. |
| 33021206 | To date we have collected eight samples from seven subjects. |
| 33022569 | Since the emergence of SARS-CoV2, to date, no effective antiviral drug has been approved to treat the disease, and no vaccine against SARS-CoV2 is available. |
| 33023050 | It should be remembered that the impact of COVID-19 on the health condition of patients with CBD is unknown to date. |
| 33023358 | However, no studies have profoundly investigated these cells in COVID-19 patients to date. γδ T cells can be safely expanded in vivo using existing inexpensive FDA-approved drugs such as bisphosphonate, in order to test its protective immune response to SARS-CoV-2. |
| 33023552 | To the best of the authors knowledge, to this date very little data exists on COVID-19 in a pediatric patient with liver transplantation. |
| 33024072 | A total of 285 patients with SARS and 2850 controls without SARS (1:10) matched for sex, age, insurance premium, comorbidities, residential regions, level of medical care, and index date were selected between February 25 and June 15, 2003 from the Inpatient Database Taiwan’s National Health Insurance Research Database. |
| 33027035 | We plotted mean daily steps and the prevalence of low daily steps (≤1,500 steps/day) 30 days before (reference period) and 30 days after (epidemic period) January 21, 2020 (date of the first COVID-19 case diagnosed in Changsha), and compared it with the same corresponding period from 2019. |
| 33027152 | We summarize lessons learned from the HIV epidemic that offer insights about how the response to COVID-19 can be improved, especially in the United States which has incurred one quarter of world’s infections to date. |
| 33027847 | There have been no reports of infection of dental staff or patients during dental treatment in China to date. |
| 33029094 | However, the pharmacological mechanism of SFJDC still remains vague to date. |
| 33029620 | This review summarizes evidence-to-date on the duration of infectivity of SARS-CoV-2, and how this has informed evolving public health recommendations on when it is safe to discontinue isolation precautions. |
| 33030209 | In addition, no studies have examined whether national distributions of these factors are associated with epidemic experiences to date. […] Both types of national risk profiles correlate meaningfully with countries’ COVID-19 mortality experiences to date. |
| 33031639 | With hundreds of studies published daily on COVID-19, for example, we struggle to find, stay up-to-date, and synthesize information-all hampering evidence-informed decision making. |
| 33031856 | To date, there are no approved vaccines or therapies for COVID-19. |
| 33032335 | In Saudi Arabia, more than 100, 000 cases of COVID-19 have been reported, and more than 4,000 in Al Hofuf to date. |
| 33032593 | To the date this paper was drafted, 38 articles were found, of which 9 satisfied our inclusion criteria. |
| 33032740 | Here, we describe mechanistic links between influenza and COVID-19 infection and the risk of acute cardiovascular events, summarize the data to date on the potential cardioprotective effects of influenza vaccines, and describe the ongoing influenza vaccine cardiovascular outcomes trials, highlighting important lessons learned that are applicable to COVID-19. |
| 33032877 | Two papers review schools: reported clusters to date globally and the specific preparations made by one specific Maltese school to try to avoid/dampen any outbreaks in the school. |
| 33032969 | This highlights the urgent need to identify high-risk individuals to offer psychological support and provide up to date information on the pandemic. |
| 33033170 | There is a shortage of effective therapeutic strategies or preventative vaccines for this disease to date. |
| 33033561 | To date, there is no effective antiviral therapy for COVID-19 patients, and therapeutic strategies are based on experience treating previously recognized coronaviruses. |
| 33035176 | To date, only anecdotal evidence has been available to indicate if the hypothesis of archetype reuse across templates is feasible and scalable. |
| 33035234 | Additionally, the association of the antibody response with both the severity of disease and the date after onset of symptoms was analyzed. |
| 33035628 | This is the largest reported cohort of CLD and cirrhosis patients with SARS-CoV-2 infection to date. |
| 33036052 | To date, more than 3.4 million people have been infected throughout the world. […] Against the background of a rapidly accumulating knowledge base on SARS-CoV-2, 68 expert authors of the current DGVS guidelines for Crohn’s disease and ulcerative colitis took part in a virtual meeting to compile up-to-date, practice-orientated recommendations aimed at improving the care of patients with IBD. |
| 33036662 | Registration date is 23 May 2020. |
| 33036812 | At our main “HOT” site, from a total of 371 separate patient encounters by date of study, 72 patient encounters (19%) were COVID-19 positive at time of exam. |
| 33038433 | To date, with the exception of intravenous Remdesivir and dexamethasone, which have modest effects in moderate to severe COVID-19, no strong clinical evidence supports the efficacy and safety of any other drugs against SARS-CoV-2. |
| 33039230 | Globally, more than 12 million people have been infected with COVID -19 infection till date with more than 500,000 fatalities. |
| 33039952 | After this date, patients were administered 1000 IU/d oral vitamin D3, 150 mg/d oral magnesium, and 500 mcg/d oral vitamin B12 upon admission if they did not require oxygen therapy. |
| 33040042 | With many regions suspending the provision of non-essential healthcare services, there is a risk that patients with common treatable illnesses do not receive prompt treatment, leading to more serious and complex presentations at a later date. |
| 33041326 | However, the pharmacokinetics and tissue distributions of the parent drug and its active metabolites have been poorly characterized to date. |
| 33041633 | By fitting the extended model to the real detected data during the lockdown, an optimization algorithm is used to derive the optimal parameters, the initial condition and the epidemics start date of regions in France. |
| 33041830 | To date, there are no proven drugs or vaccines against this virus. |
| 33042602 | There is a paucity of published studies to date that investigate how display type affects pathologist performance, with more research necessary in order to develop standards and minimum specifications for displays in digital pathology. |
| 33042952 | To date, there have only been a total of 92 indigenous COVID-19 cases confirmed in the Gansu Province, which is considered to be a consequence of the strict screening approach applied during the outbreak. |
| 33043030 | However, to date, there is no sufficient evidence of the effectiveness of any researched therapy. |
| 33043784 | To date, millions of confirmed cases and hundreds of thousands of deaths have been reported worldwide, and there are currently no medical countermeasures available to prevent or treat the disease. |
| 33044199 | Please relate the information to the date on which it was written. |
| 33045008 | Peak infection date varied across scenarios and counties; on average, increasing shelter-in-place duration delayed the peak day by 6 days. |
| 33047475 | To date, little is known about the duration and effectiveness of immunity as well as possible adverse late effects after an infection with SARS-CoV-2. |
| 33047816 | We placed no restrictions on the language or date of publication. |
| 33048300 | This has drawn sharp criticism within the scientific community, with the approval being granted on the basis of a relatively small phase II trial, without conduct of a conventional phase III trial, and lacking availability of the claimed supportive real-world evidence in the public domain to date. |
| 33048801 | To date, however, there is no evidence of HIV infection worsening the evolution and prognosis of COVID-19. |
| 33048824 | The outcome of the model for the patient’s application was the length of time from the date of hospitalization to the date of the first usage of an oxygen supplement. |
| 33048825 | Given the potential of undermining global efforts in COVID-19 disease control, up-to-date public health strategies are required to counter proliferation of misinformation. |
| 33049279 | Although numerous antiviral and anti-parasitic drugs are under clinical trials to combat this pandemic, to date, neither a specific treatment nor any successful vaccine has been established, urging researchers to identify any potential candidate for combating the disease. |
| 33049563 | As on date, the traditional polymerized chain reactions (PCR), lateral flow devices (LFID) and enzyme linked immunosorbent assays (ELISA) are being adapted for the detection of this deadly virus. |
| 33050869 | Till date, there exists no effective vaccine or therapy against COVID-19. |
| 33050945 | Since the recruitment ended earlier than expected (the expected recruitment end date was 21/12/2020), we submitted post recruitment but prior to publication of the results. |
| 33051386 | Neuromuscular complications such as cerebrovascular disease, encephalopathy, meningoencephalitis, peripheral neuropathy, and myositis/myopathy have been reported to date. |
| 33052259 | To date, treatment to protocol has relied on standard face-to-face delivery. |
| 33052311 | Nevertheless, to date we lack a geographical description of this trifecta that can be applied strategically to pandemic prevention. |
| 33052317 | Until the same date patients quarantined at home were 43,752, whereas hospitalized patients were 31,776, of which 3981 in intensive care. […] The active cases (i.e. the number of patients not yet recovered until that date) were 75,528. |
| 33052958 | We derived the epidemic growth rates (r) and the corresponding reproductive numbers (R) from the epidemic curve of these 1,311 individuals with laboratory-confirmed diagnosis of COVID-19 using their date of test collection as a proxy for symptoms onset. |
| 33053023 | Patients with COVID-19 and on mechanical ventilation in this series presented clinical variables similar to those described to date in other international reports. |
| 33053582 | However, the number of daily infection cases, hospitalization rate, lag time from onset to diagnosis date and their associations with measures introduced to slow down the spread of COVID-19 have not been fully explored. […] All of the patients had an onset date from 21 December 2019 to 23 February 2020. […] The overall and weekly hospitalization rate and lag time from onset to diagnosis date were calculated. |
| 33054027 | To date, descriptive results of a clinical and morphological study of novel coronavirus COVID-19 infection, mainly of the lungs, have appeared. |
| 33054679 | Since this date, the Vascular Surgery Unit started a “scaled-down” activity, both for elective surgical procedures and for the outpatient Clinical activities; different protocols were developed for health preservation of staff and patients. |
| 33055501 | To date, there are no comprehensive data on pediatric COVID-19 from Latin America. |
| 33057955 | This review reports on the most highlighted polyphenolic compounds present in up to date literature and their specific antiviral perceptive properties that might enhance the body immunity facing COVID-19, and other viral infectious diseases. |
| 33058643 | It appeared in December 2019 in China and has spread rapidly affecting more than 2.5 million people with more than 177,000 deaths worldwide to date. |
| 33058941 | Only studies assessing the virucidal effect of hydrogen peroxide mouthwash were selected, regardless of publication date. |
| 33059225 | To date, no attention has been given to the accumulation of killed/inactivated/degenerated SARS-CoV-2 associated molecular particle patterns (SAMPPs). |
| 33060093 | Individual information on age, sex, occupation, residence location, date of illness onset, date of diagnosis and clinical outcome was extracted. |
| 33061265 | Hence, we conducted a scoping review of all available literature till date to fill in the “potential” gaps in currently available knowledge on ocular manifestations of SARS-CoV-2 infection in an attempt to establish continuity in the “chain of information” from December 2019 till April 2020. […] The commonest ocular manifestation in SARS-CoV-2 infection is follicular conjunctivitis and has been the first manifestation of SARS-CoV-2 infection in 3 reported cases till date. |
| 33061304 | To date, rigorous results from clinical trials using MSCs in human have been weakly positive. |
| 33062489 | This is the first such case reported in Australia to date. |
| 33063034 | Controls were identified using a 2:1 hierarchical process that matched for 1) date and unit of admission; 2) specific organ support modalities; 3) age; 4) chronic lung, cardiovascular, and kidney disease; and 5) sex. |
| 33063150 | Although the impact of the pandemic on organ activity has been analysed, to date, less data exist regarding the impact on tissue activity. |
| 33063241 | Two estimation methods of ICU_ALOS were compared: the average LOS of already discharged patients at the date of estimation (DPE), and a standard parametric method used for analyzing time-to-event data which fits a given distribution to observed data and includes the censored stays of patients still treated in the ICU at the date of estimation (CPE). […] At the last follow-up date, 99 days after the first admission, all patients but one had been discharged. […] CPE and DPE estimates were also compared to COVID-19 estimates reported to date. […] Series’ true ICU_ALOS was greater than 21 days, well above reported estimates to date. […] Cautious unbiased ICU_ALOS estimates suggest parameterizing a higher burden of ICU bed occupancy than that adopted to date in COVID-19 forecasting models. |
| 33063649 | Therefore, it is crucial for businesses to stay up-to-date not only with the released guidances but also with the latest understanding and information about SARS-CoV-2. |
| 33064679 | The information collected about the induction of an immune response by SARS-CoV-2 will be presented, as well as a description of the vaccine candidates reported to date in the various ongoing clinical trials. |
| 33065092 | On August 16, 2020, the World Health Organisation had reported 2,1294,845 cases which are confirmed to date out of which 413,372 deaths have occurred. |
| 33065163 | ClinicalTrials.gov number: NCT00850629, https://clinicaltrials.gov/ct2/show/NCT00850629, date of registration: February 25, 2009. |
| 33065278 | To date there are no data relating to SARS-CoV-2 in PCOS women. |
| 33065421 | This is the largest survey to date addressing changes in pediatric rheumatology practice due to the COVID-19 pandemic. |
| 33066801 | Third, we assessed the association between viral presence in LRT and mortality using mixed-effect logistic models for clustered data adjusting for the time between symptoms’ onset and date of sampling. […] This difference was statistically significant after adjusting for the time interval between onset of symptoms and date of sampling (OR 3.78, 95% CI 1.13-12.64, p = 0.03). |
| 33067013 | Independent factors associated with caregivers’ willingness to accept expedited COVID-19 vaccine research included having children who were up to date on the vaccination schedule (odds ratio [OR] = 1.72; 95% CI, 1.29-2.31), caregivers’ concern about having had COVID-19 themselves at the time of survey completion in the ED (OR = 1.1; 95% CI, 1.05-1.16), and caregivers’ intent to have their children vaccinated against COVID-19 if a vaccine were to become available (OR = 1.84; 95% CI, 1.54-2.21). |
| 33067299 | Studies published on any date containing primary data comparing surgical facemasks and respirators specific to SARS-CoV-2, and studies underpinning UK Government PPE guidance, were included. |
| 33067353 | Likewise, there was a significant increase in the number of patients offered testing during virtual care who did not provide a blood sample (176/180 (97.7%) vs 180/243 (74.1%); p<0.001), and a longer median time from the date of pretest genetic counselling to the date a sample was given (0 vs 11 days; p<0.001). |
| 33068412 | Specially, RASP curates the up-to-date datasets of several RNA secondary structure probing studies for the RNA genome of SARS-CoV-2, the RNA virus that caused the on-going COVID-19 pandemic. |
| 33068611 | Additionally, as the Center for Medicare and Medicaid Services (CMS) has revised telemedicine reimbursement and encouraged its increased use, it has provided no guidance for the sterilization consent form, use of oral consents, and change to the sterilization consent form expiration date. |
| 33069048 | A literature review was performed using PubMed and Ovid servers without date or language restrictions. |
| 33069206 | This new strain of coronavirus is not completely understood and to date, there is no treatment for coronavirus. |
| 33069360 | Most of the SARS-CoV-2 neutralizing antibodies to date target the spike (S) protein receptor binding domain (RBD), which engages the host receptor ACE2 for viral entry. |
| 33069725 | Subgroup analyses were based on geographic distribution, study type, quality assessment, sample size, end date, and patient disposition. |
| 33070389 | BioGRID-ORCS contains datasets for over 1,042 CRISPR screens carried out to date in human, mouse and fly cell lines. |
| 33071002 | A univariate and subsequent multivariate analysis found that increased intended uptake was associated with children that were older, children with no chronic illness, when fathers completed the survey, children up-to-date on their vaccination schedule, recent history of vaccination against influenza, and caregivers concerned their child had COVID-19 at the time of survey completion in the ED. |
| 33071145 | Higher temperatures and high relative humidity can have a modest effect on SARS-CoV-2 viability in the environment, as reported in previous studies to this date. |
| 33072084 | To date, Stronger data in favor of their clinical use are provided in the prevention of gastrointestinal disorders, antibiotic-associated diarrhea, allergy and respiratory infections. |
| 33072461 | In Dec 2019, a novel pathogen emerged, and within weeks, led to the emergence of the biggest global health crises seen to date. |
| 33072509 | To the best of our knowledge, there is no case report or data published regarding COVID pneumonitis presenting initially as pneumothorax.There are 3 case reports published to-date (May 30, 2020) reporting secondary pneumothorax as complication in later stages of Acute respiratory distress syndrome (ARDS) secondary to COVID-19 in non-ventilated patients. |
| 33072810 | Disease duration was calculated from the date of symptom onset to the date of specimen collection and divided into 3 groups: ≤14 days, 14-21 days, and >21 days. |
| 33072871 | To date there is no cure and no vaccine is available. |
| 33073202 | While no cure is available to date, herein we put forward with rationale and supporting evidence that if administrated simultaneously, a combination of FDA-approved drugs comprising ivermectin, famotidine, and doxycycline may provide robust chemoprophylaxis effective against COVID-19. |
| 33073251 | The dominant and consistent concentration of workforce research to date has focused on attitudinal factors including job satisfaction and burnout and there is limited research on how organisational commitment in combination with job satisfaction and burnout may explain what keeps nurses in nursing. |
| 33074995 | Gastroenterologists should stay up-to-date with the rapidly evolving literature regarding gastrointestinal symptoms in COVID-19 patients as well as its impact on chronic gastrointestinal illnesses. |
| 33075530 | To date, a direct link between chilblains and COVID-19 still seems impossible to confirm. |
| 33077309 | Outcome, complications, and treatments were monitored until May 6, 2020, the final date of follow-up. |
| 33077985 | In this contribution the most up to date indications on the use of facial masks by health care workers and general population, for the prevention of contagion are discussed and confronted. |
| 33078010 | On the same date, as the commercial activities were still regularly open, the dinner, which saw as protagonists the participants of this retrospective study, took place. |
| 33078074 | To date, no recommendations have been published on when and how to start again carrying out elective, non-urgent surgery on COVID-19-negative patients after the epidemic peak has been reached in a given country or region and the pressure on healthcare facilities, healthcare workers and resources has been released by so far that elective surgery procedures can be safely and ethically programmed again. |
| 33078089 | To date, there is no specific treatment or vaccine for COVID-19, thus staying at home is the best preventive measure to curb the further growth of positive cases in the country. |
| 33079693 | We extracted study characteristics such as the paper title, journal, and publication date, and we categorized the retrieved papers by the type of technology and patient needs addressed. |
| 33080051 | Some of these patients are under oral anticoagulation (OAC) at admission, but to date, there are no data on the clinical profile, prognosis and risk factors of such patients during hospitalization for COVID-19. |
| 33081851 | However, little is known about the epidemic dynamics in different age groups during these periods.We used the daily number of coronavirus 2019 cases (by date of symptom onset) reported to the National Epidemiological Surveillance Network among individuals aged 15-19 years through 65-69 years. |
| 33081867 | To date, human, technological and institutional barriers may have held back the integration of such approaches in routine clinical practice, particularly in the UK. |
| 33081889 | The clinical date of critical COVID-19 patients undergoing IMV who were hospitalized in Wuhan Union Hospital, Tongji Medical College of Huazhong University of Science and Technology from February 4th to March 25th in 2020 were collected. |
| 33082338 | To date, all available studies designed to investigate the psychological effects of this unprecedented global crisis are based on cross-sectional surveys that do not capture emotional variations over time. |
| 33082630 | The severe acute respiratory syndrome coronavirus 2 has emerged as an alarming disease since December 2019, claiming the lives of thousands across the world to date. |
| 33082924 | We describe here the impact, changes, and outcomes achieved by a large, multifaceted ABA clinical program that has (a) ongoing data that forecasted and tracked changes, (b) staff well practiced with data-based shifts in operations (behavior), and (c) up-to-date information (data) on policy and regulations. |
| 33083387 | Numerous therapeutic strategies have been used until now but, to date, there is no specific effective treatment for SARS-CoV-2 infection. |
| 33083500 | Symptoms and possible treatment till date is well defined in this paper. |
| 33083695 | To date, the reported cases of neurological and neuromuscular complications associated with coronaviruses, especially COVID-19, are increasing. |
| 33083773 | However, precise quantification of olfactory loss in asymptomatic COVID-19 carriers is missing to date. |
| 33085079 | The following recommendations, based on current knowledge of the disease and therefore liable to change in the future, are proposed when the pandemic appears to have entered a process of decreasing virulence and, with it, the strict containment measures established to date. |
| 33087207 | In this study, we look at the clinical characteristics, possible causes, pathogenesis, and infectivity of re-detectable positive patients and provide up-to-date information to public health policy planners and clinicians. |
| 33087610 | Information and Communication Technology (ICT) can be a valuable tool in providing tools for self-assessment and reporting of physical symptoms, early detection of symptom changes, up to date information towards citizen empowerment, personalized recommendations and communication with healthcare providers in case of need. |
| 33088093 | Unfortunately, there is no approved medication for treatment, till date, thereby supporting triage management and difficult decision-making. |
| 33088153 | This review will highlight the latest source information on clinical observation/outcomes of the IBD population and provide a concise summary of the most up to date perspectives on IBD management in the age of COVID-19. |
| 33088905 | Coronavirus disease 2019 (COVID-19) has rapidly evolved into a global pandemic, with affecting to-date over 23 million people and causing over 800,000 deaths around the globe. |
| 33089046 | To date, COVID-19 pneumonia associated with a VT storm as the main manifestation of cardiac involvement has never been reported. |
| 33089707 | To date, neurological manifestations of COVID-19 have been described largely within the disease trajectory and the long-term effects of such manifestations remain unknown. |
| 33089717 | While awaiting the results of significant clinical studies, which to date do not exist, the commercial availability of mouth rinses leads us to search among them for reagents that would have specific antiviral properties with respect to SARS-CoV-2. |
| 33090440 | The daily cases, deaths, particulate matter (PM-2.5 μm) and carbon monoxide were documented from the date of the occurrence of the first case of (SARS-CoV-2) in San Francisco, CA, USA, from March 20, 2020 to Sept 16, 2020. |
| 33090686 | The findings to date suggest pervasive inequities across common conditions and injuries in physical medicine and rehabilitation for this group compared to other racial/ethnic groups. |
| 33090710 | The final date of follow-up was 21 March 2020. |
| 33091230 | To date, two potential cases of animal-to-human transmission are being investigated, on infected mink farms. |
| 33091285 | However, to our knowledge, there are no reports to date of the utilization or results of repeat testing to help guide this practice. |
| 33091590 | This review mainly focused on the brief up to date information about COVID-19, molecular characterization, pathogen-host interaction pathways involved during COVID-19 infection. |
| 33092632 | The anticipated date of recruitment completion is April 30, 2021. |
| 33092637 | Therefore, we deemed it prudent to review the associations between specific human genetic variants and clinical disease severity or susceptibility to infection that have been reported in the literature to date (at the time of writing this article in early August 2020 with updates in mid-September). |
| 33093376 | To date, pancreatitis has not yet been reported in either acute SARS-CoV-2 infection in children or the subsequent inflammatory syndrome. |
| 33094260 | To date members of 18 departments across the Trust have delivered 51 virtual teaching sessions which have been viewed 3,814 times. |
| 33094701 | To date, ∼530,000 people died of this disease worldwide. |
| 33095253 | A secondary outcome was subsequent COVID-19 fatality rates, derived using mean cumulative fatality rates 21 to 28 days after each date. |
| 33095841 | Overall unadjusted survival at 1 week after date of positive COVID-19 test was 87.5% (95% CI 86.1-88.8%); mortality increased with age, treatment vintage and there was borderline evidence of Asian ethnicity (HR 1.16, 95% CI 0.94-1.44) being associated with higher mortality. |
| 33095853 | We used Kaplan-Meier methods and Cox regression to describe the association between HIV status and day-28 mortality, after separate adjustment for sex, ethnicity, age, hospital acquisition of COVID-19 (definite hospital acquisition excluded), presentation date, ten individual comorbidities, and disease severity at presentation (as defined by hypoxia or oxygen therapy). |
| 33098835 | To date, no SARS-CoV-2-explicit drug has been reported, but we here introduce bioactive peptides in the perspective of their potential activity against SARS-CoV-2 infection. |
| 33100531 | To date, there are no approved treatments for SARS-CoV-2, and current management is focused on supplemental oxygen and supportive care. |
| 33101291 | To date, no specific treatment or vaccine is available for COVID-19. |
| 33102187 | We have done 5 cochlear implants surgeries till date. |
| 33102987 | Till date, about twenty four million people around the world are infected due to the SARS-CoV-2. […] Till date, no medicine or vaccine is in the market to cure from the infection. |
| 33103442 | During the outbreak of coronavirus disease 2019 (COVID-19), many studies have investigated laboratory biomarkers in management and prognostication of COVID-19 patients, however to date, few have investigated arterial blood gas, acid-base and blood pressure patterns. |
| 33103715 | This project conducted during the 2019 coronavirus (COVID-19) pandemic reflects the largest clinical cohort to date of TeleNP in a pediatric population (N = 129). |
| 33104517 | To date, limited information is available on Canadian older adults’ attitudes toward and use of mHealth technologies for self-tracking purposes-an area that is increasingly important and relevant during the COVID-19 era. |
| 33106134 | This brief review aims to prompt identification of risk factors and main adverse effects in a systematic view related to therapy with partial evidence proposed to date. |
| 33106171 | The registration date was 14 August 2020. |
| 33106183 | Geneva: World Health Organization) or discharge from the hospital, whichever comes first. mortality from the date of randomization until the last day of the study which will be the day all of the patients have had at least one of the following outcomes: 1) Improvement of two points on a seven-category ordinal scale. […] Improvement of SPO2 during the hospitalization, duration of hospitalization from date of randomization until the date of hospital discharge or death, whichever comes first. […] The incidence of new mechanical ventilation uses from the date of randomization until the last day of the study and the duration of it will be extracted. |
| 33106717 | To date, there are no specific, clinically significant licensed drugs and vaccines available for COVID-19. |
| 33106780 | To date, there is no medicine and vaccine available for COVID-19 treatment. |
| 33106832 | To the date of Sep. 13th, 2020, COVID-19 is affecting 216 countries or regions, causing 28 637 952 cases, 917 417 deaths, and the mortality rate is 3.20%. |
| 33107677 | To date, this is the first large-scale study to report the rates of trauma and burnout for nurses during the COVID-19 pandemic. |
| 33109039 | To date, the farthest in the drug development pipeline so far is Remdesivir. |
| 33109244 | The registration date is 17 May 2020. |
| 33109299 | Only a few such randomised trials have already been conducted, but the ones done to-date demonstrate that a randomised trials agenda is feasible. |
| 33109863 | A 12-item questionnaire on surgeries performed in the 6 weeks prior to the survey date, PPE usage, and preoperative SARS-CoV-2 testing was circulated electronically to Indian neurosurgeons from May 12, 2020 to May 31, 2020 and their responses analyzed. |
| 33110585 | To date, the pandemic has been successfully controlled thanks to the Vietnamese government’s prompt, proactive and decisive responses including mobilization of the health care systems, security forces, economic policies, along with a creative and effective communication campaign corresponding with crucial milestones of the epidemic’s progression. |
| 33110762 | Symptoms of psychological distress and depression measured by the K-10 and PHQ-9, and the proportion reporting suicidal thoughts and plans did not change, and to date we have not identified indications of a mental health crisis. |
| 33110844 | Till date more than 200 COVID-19 patients have been admitted here. |
| 33112411 | This is the largest study of patients with cancer versus patients without cancer to date and is the first multivariate analysis study comparing these 2 patient populations. |
| 33113146 | The mainstay of management of coronavirus disease 2019 (COVID-19) is mainly supportive as to date there is no effective antiviral treatment, apart from remdesivir which has been approved by Food and Drug administration (FDA) for treatment of COVID-19, or vaccine. |
| 33114779 |
|
| 33116032 | To date, no study has examined ECMO-related bleeding and AVWS in COVID-19 patients.We report a COVID-19 patient who experienced bleeding from AVWS in addition to disseminated intravascular coagulation (DIC) during ECMO. |
| 33116300 | Although the previous coronavirus SARS-CoV and MERS-CoV epidemics raised awareness of the need for clinically available therapeutic or preventive interventions, to date, no treatments with proven efficacy are available. |
| 33116555 | Evidence to date suggests that having chronic conditions increases the probability of severe illness from severe coronavirus disease 2019 (COVID-19). |
| 33116556 | Therefore, it is crucial that they have up-to-date information on vaccinological interventions that reduce the risk of transmission of SARS-CoV-2 infections. |
| 33116688 | To date, more than 35 million people worldwide have been infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent of coronavirus disease 2019 (COVID-19), and more than one million have died in the COVID-19 pandemic. |
| 33116976 | The combined staged and quarantined IPC policy led to the fewest confirmed cases caused by work resumption in Shanghai, and the spread of COVID-19 stopped (ie, the number of newly confirmed cases reduced to zero) at the earliest date. |
| 33116980 | To date, no specific vaccines and drugs have been developed for this disease. |
| 33117508 | The analysis of the literature indicates that to date, a certain positive experience has been accumulated in the world in the application of extracorporeal methods in clinical practice in patients with COVID-19. |
| 33117535 | To date, the effects of COVID-19 pneumonia on health-related quality of life (HRQoL) and dyspnoea are unknown. |
| 33118527 | As of date, there is no approved vaccine or treatment for COVID-19 though there are ongoing research studies to formulate a treatment. |
| 33118913 | To date, little evidence on COVID-related concerns have been produced and no report has provided structured feedback from the point of view of people with intellectual disabilities and/or autism or of their family/carers. |
| 33118945 | These included terms of use, time zone configuration to reflect local time and date, safety and moderation protocols, the need help now feature, and the list of trigger words to flag posts indicative of potential risk. |
| 33119139 | To date, 18 living recommendations for the clinical care of pregnant and postpartum women with COVID-19 have been issued by the National COVID-19 Clinical Evidence Taskforce. |
| 33119536 | Data from each post was also recorded as follows: date of post, headline, number of “likes,” number of messages left, number of shares, video or non-video post, and date of search. |
| 33120327 | To date, we have completed 24 teleNP assessments: 18 remotely (participant in own home) and six on-site (participant using equipment at research facility). |
| 33120619 | The donor cornea retrieval was resumed in a strategized manner 3 weeks prior to the date of exit of the lockdown, with modified guidelines on donor suitability, screening, retrieval, processing, and harvesting from various sources. |
| 33120648 | While elective eye surgeries such as uncomplicated cataract surgeries, blepharoplasty and eyelid procedures and refractive surgeries can be planned at a later date; emergency cases pertaining to ocular trauma cannot be deferred. |
| 33120812 | Up-to-date information on the current progress made in the research and development to control the global COVID-19 pandemic is important. |
| 33121591 | Most published commentary has been around the Mental Health Nurse Incentive Program, but, to date, scholarly work related to this program has not influenced public views and policy formation despite multiple favourable evaluations. |
| 33121920 | This review is consequently an endeavour to highlight the several aspects of COVID-19 with incorporation of important treatment strategies discovered to date and putting the real effort on the future directions to put them into the perspective. |
| 33122319 | To date, 106 of 201 requests received approval, 5 have been declined, 27 withdrew and 27 are in the revision stage. |
| 33122620 | Elevated D-dimer levels, COVID-19-associated coagulopathy (CAC), disseminated intravascular coagulation (DIC), and positive lupus anticoagulants are the most common findings to date. |
| 33123514 | Systematic evidence quantifying the crime opportunities posed by synthetic biology has to date been very limited. |
| 33123776 | The study comprised year-to-date intervention analyses of in- and outpatient key procedures, machine occupancy, and no-show rates in calendar weeks 12 to 19 of 2019 and 2020 to evaluate effects of active patient flow management while monitoring nosocomial COVID-19 infections. |
| 33124029 | The global coronavirus disease 2019 (COVID-19) pandemic has deranged the recent history of humankind, afflicting more than 27 million individuals to date. |
| 33124193 | To date, there are still no effective approaches for the prevention and treatment of COVID-19. |
| 33125393 | To demonstrate the efficiency of the model and approach, we also provide a tentative forecast two months ahead of time, i.e. until May 4, the date on which relaxation of the measures commenced, on the basis of the COVID-19 Community Mobility Reports released by Google on March 29. […] On May 4, the date on which relaxation of the measures commenced the effective reproduction number was found to be 0.987 (interquartiles: 0.857, 1.133). |
| 33126204 | The NCCN Best Practices Committee, which is composed of senior physician, nursing, and administrative leaders at NCCN Member Institutions, conducted a webinar series in June 2020 highlighting the most promising and effective strategies to date. |
| 33128861 | To date, the molecular mechanism of transmission of SARS-CoV-2, its clinical manifestations and pathogenesis is not completely understood. |
| 33129363 | The date recruitment started was May 21, 2020 and the investigators anticipate the trial will finish recruiting by the end of December 2020. |
| 33130197 | We summarize here the results from randomized controlled trials (RCT) published to date and analyze their flaws and biases. |
| 33132534 | In this context, we present six new boarding methods and compare their performance with that of the two best boarding methods used to date with social distancing. |
| 33133127 | The present paper meets those demands by providing mathematical developments that implement classical models of genetic effects and bring them up to date with the prospects current available data bestow. |
| 33133827 | To date, no case of severe hemolytic anemias with stress cardiomyopathy/acute myocarditis in a patient of COVID-19 has been formally reported in the literature. |
| 33133990 | To date, no safety guidelines are available for safe reconstructive microsurgical procedures in high-risk operations/known COVID-19 patients-particularly, to address operations risk and COVID-19 status of the patients, who would operate, how many should be involved, how to equip the surgeons for the procedure, when to operate as the procedure unfolds, how to adapt surgical techniques to reduce exposure risk, and can advanced technology be used to minimize exposure. |
| 33134308 | From December 2019 to date, more than 22 million cases have been reported worldwide and global health institutions are acting to slow down the virus transmission and are looking for possible prevention strategies in case of a new outbreak. |
| 33134944 | Several risk stratification tools were developed to predict disease progression in coronavirus disease 2019, with no external validation to date. |
| 33135085 | To date, the exact route/routes of transmission of COVID-19 are still unclear. |
| 33135788 | This study provided up-to-date evidence of several clinical and epidemiological characteristics in the association with COVID-19 recurrence cases. |
| 33136249 | In this article we assess the impact of missteps by the Federal Government in three specific areas: the introduction of the virus to the US and the establishment of community transmission; the lack of national COVID-19 workplace standards and enforcement, and lack of personal protective equipment (PPE) for workplaces as represented by complaints to the Occupational Safety and Health Administration (OSHA) which we find are correlated with deaths 16 days later (ρ = 0.83); and the total excess deaths in 2020 to date already total more than 230,000, while COVID-19 mortality rates exhibit severe-and rising-inequities in race/ethnicity, including among working age adults. |
| 33136293 | The follow-up cutoff date was July 22, 2020. |
| 33138197 | Despite the established antimicrobial and immune-boosting potency described for honey, to date there is still a lack of evidence about its potential role amid COVID-19 outbreak. |
| 33138652 | To date, an effective drug for reliable treatment of COVID-19 has not been registered or introduced to the international community. |
| 33138721 | Historically, three major pharmacological approaches have been employed to treat FIP: (1) immunomodulators to stimulate the patient’s immune system non-specifically to reduce the clinical effects of the virus through a robust immune response, (2) immunosuppressive agents to dampen clinical signs temporarily, and (3) re-purposed human antiviral drugs, all of which have been unsuccessful to date in providing reliable efficacious treatment options for FIPV. |
| 33138836 | To date, twenty-six studies have used SARS-CoV-2 nucleic acid in plasma or serum (RNAaemia) to diagnose COVID-19. |
| 33138974 | The date of final follow-up was June 4, 2020. |
| 33139290 | Here, clinical trials published to date are presented and appraised. |
| 33140176 | The final date of follow-up was 6 May 2020. |
| 33140444 | To date, limited discussion exists about conceptualizing public libraries as health literate multi-purpose workspaces for supporting and sustaining public library health literacy efforts. |
| 33140636 | To date, several peptides have been proposed against SARS-CoV-2 both as inhibitor agents or as detection tools that can also be attached to the surfaces of nanoparticle carriers. |
| 33140690 | Till date, there is no promising drug or vaccine available in market to cure from this lethal infection. |
| 33140740 | This work analyses the evaluation conducted by our Regional Ethics Committees during the initial period of the health emergency (between 13th March and 28th May 2020). 81 research projects were evaluated, 73 of them of regional scope (62 single-centre), 4 national and 4 international. 57 projects obtained a favourable opinion, 4 were withdrawn by the sponsors, 6 did not require ethics approval and 14 did not respond to the clarifications requested up to the date of the study’s closure. |
| 33141806 | Multiple organizations have developed guidance, but to date, no comparative summary has emerged to understand differences in existing recommendations. |
| 33141813 | The worldwide interest in this new disease is reflected in the increasing number of intervention studies that are being carried out to date. |
| 33142123 | Pregnant women have unique needs during infectious disease outbreaks and could benefit from up-to-date, consistent information and guidance; appropriate support and advice from healthcare professionals, particularly with regards to the risks and benefits of prophylaxis and treatment; virtual support groups and designating locations or staff specifically for pregnant women. |
| 33142828 | The evidence to date generally satisfies Hill’s criteria for causality in a biological system, namely, strength of association, consistency, temporality, biological gradient, plausibility (e.g., mechanisms), and coherence, although experimental verification is lacking. |
| 33143799 | However, it also shows that apparent control has only been partially achieved to date. |
| 33144493 | To date, there are no established methods of infection control. |
| 33145146 | Based on the COVID-19 data to date and our experience, we present testing, management, and prevention methods for COVID-19. |
| 33145147 | Up-to-date epidemiological data is needed on which to base an appropriate decision regarding the Tokyo 2021 Olympics. |
| 33145303 | SARS-CoV-2 RNA and plasma antibody levels were measured, and all patients were followed up for at least 14 days, with a cutoff date of March 10, 2020. |
| 33146552 | Patients should remain up to date with appropriate vaccinations, particularly annual influenza vaccination. |
| 33146625 | To date, no confirmed transmission of the virus has been confirmed within a laboratory setting; however, operating processes and procedures should be adapted to ensure safe working of samples of positive, negative, or unknown COVID-19 status. |
| 33146785 | The date ranges in 2020 mark the early COVID-19 pandemic period in BC and the large shift in operating room access during this time. |
| 33147345 | The Day 5 model to predict trigger date has a mean squared error 2.16 ± 0.12 and to predict over-response an area under the receiver operating characteristic curve 0.91 ± 0.01. |
| 33147503 | To date, several sphingolipid derivatives are known, but S1P (Sphingosine-1-phosphate) and Ceramide are the best-studied sphingolipid derivatives in the context of human diseases. |
| 33147584 | To date, little is known about the characteristics of pulmonary auscultation in novel coronavirus (COVID-19) pneumonia. |
| 33147660 | This article includes an overview of the up-to-date international and U.S. treatment guidelines for psoriasis, atopic dermatitis, hidradenitis suppurativa, and acne/rosacea; it provides tables summarizing these resources to assist providers and patients in remaining updated regarding recommended treatment modifications during the pandemic (See Tables 1-4). |
| 33147715 | The availability of computerized clinical guidance and an up-to-date knowledge base play a role in Saudi health organizations, which may not have to constantly train their physician staff and may no longer have to rely on international experts, since the expert system can offer clinicians all the information necessary to treat their patients. |
| 33147840 | Since whole genome sequencing (WGS) data is very crucial to understand the spreading dynamics of the ongoing pandemic, but only limited sequencing data is available from the Sahel region to date, we have focused our efforts on generating the first Malian sequencing data available. |
| 33148714 | To date, the vast majority of the serological tests for SARS-CoV-2-specific Abs are based on serum detection of Abs to either the viral spike glycoprotein (the major target for neutralizing Abs) or the viral nucleocapsid protein that is known to be highly immunogenic in other coronaviruses. |
| 33148777 | The outcome measure was the proportion of patients surviving at time t (time from the positive result of COVID-19 test to discharge/death date). |
| 33149917 | To date, there are four cases of tension pneumothorax in patients with COVID-19, published in literature. |
| 33151142 | Unfortunately, no vaccine or antiviral drug that completely eliminates the transmissible disease coronavirus disease 2019 (COVID-19) has been developed to date. |
| 33151287 | DrugCentral is a public resource (http://drugcentral.org) that serves the scientific community by providing up-to-date drug information, as described in previous papers. |
| 33152188 | To date, certain comorbidities are known to be risk factors for unsatisfactory disease outcomes, but little has been reported regarding hemodialysis patients despite being a population at high risk of infection, complications, and death.Here we describe the clinical course, clinical manifestations and complications of COVID-19 in seven patients on permanent hemodialysis. |
| 33152196 | To achieve comparability, the analyses considered the day the first case was diagnosed as the first analysis date for each department. |
| 33152279 | To date, mouse, hamster, ferret, guinea pig, and non-human primates have been investigated. |
| 33153991 | This up-to-date review tackles some of the key issues which have significant impact on the long-term outlook for COPD patients in the context of COVID-19. |
| 33154232 | Till date, randomised controlled studies for the use of CP in SARS-CoV-2 infection are lacking, and many countries have invited institutions to participate in clinical trials. |
| 33155252 | Since the service situation is changing quickly; surgeons should be up to date with the local and national guidelines. |
| 33155834 | To date, the analysis of fatal cases and the risk factors for death have rarely been reported. |
| 33155887 | To date, there is no significant exact medication is available to treat Covid-19 as a result both the death toll and the number of people affecting by this disease is increasing every day. 35 phytochemicals having antiviral properties were taken to get the best compounds against Nsp1 Materials and Methods: As no PDB structure of this protein is available, homology modeling was done to predict the probable structure. |
| 33155905 | Till date, there are no optional treatment or prevention options. |
| 33156806 | To date, studies have not compared people’s experiences with telehealth services during the pandemic in Australia to their experiences with traditional in-person visits. |
| 33157297 | To date, the SARS-CoV-2 infection prevalence is 0.70% among exposed HCWs and 0.435% among all HCWs working at the examined university hospital. |
| 33158456 | This LSR will provide an in-depth and up-to-date summary of whether the common neuropsychiatric conditions observed in patients hospitalized for severe acute respiratory syndrome (SARS-CoV) and Middle East respiratory syndrome (MERS) are also prevalent in a different stage of COVID-19 patients. |
| 33159728 | To date, most patients have exhibited hypercoagulability on viscoelastic tests not detected by standard coagulation tests. |
| 33160066 | To date, no study has been published on viral kinetics during the preclinical and clinical periods of SARS-CoV-2. |
| 33160264 | This positive correlation persists even when controlling for date of first death, presence of lockdown, Covid tests per capita, hospital beds per capita, proportion of elderly, GDP per capita, government’s political orientation, percentage urban, and rental prices. |
| 33162558 | However, the obligations of the employee and the employer must be fulfilled in this respect immediately, but not later than within 60 days from the date of the epidemic cancellation. |
| 33162725 | To date, despite the great debate regarding the best seating arrangement for learning in classrooms, no empirical studies have examined the direct effects of different seating arrangements on children’s cognitive processes. |
| 33163105 | These data made it possible to better understand the origin of this virus, to date its emergence in China, but also in France, and to analyse the spread of the epidemic using techniques from the emerging field of phylodynamics. |
| 33163106 | Even though data and knowledge on the emerging disease were patchy, a wide variety of models were developed and applied in unprecedented timeframes, with the aim of estimating the reproduction number, the starting date of the epidemic or the cumulative incidence, but also to explore different scenarios of non-pharmaceutical interventions. |
| 33163107 | Since that date, and until the beginning of September, 3 374 cases have been diagnosed, including 75 cases in intensive care unit which progressed to death in 40 cases. |
| 33163683 | To date 32,174,627 cases, of which 962,613 (2.99%) have died, have been reported (https://www.who.int/westernpacific/health-topics/coronavirus, accessed 23 Sep 2020). |
| 33163859 | To date, there are no effective pharmaceutical treatments available. |
| 33165237 | No case of donor-derived COVID-19 has been reported to date. |
| 33166390 | To date, the COVID-19 Open Research Dataset (CORD-19), lists ∼130,000 articles from the WHO COVID-19 database, PubMed Central, medRxiv, and bioRxiv, as collected by Semantic Scholar. |
| 33166392 | This is causing an increasingly serious information overload, making it difficult for scientists, healthcare professionals and the general public to remain up to date on the latest SARS-CoV-2 and COVID-19 research. […] Hence, we developed LitCovid (https://www.ncbi.nlm.nih.gov/research/coronavirus/), a curated literature hub, to track up-to-date scientific information in PubMed. |
| 33166657 | To date, despite the fact that millions of SARS-CoV-2 infections have been diagnosed worldwide, there is no definitive proof that SARS-CoV-2 is a novel cardiotropic virus causing direct cardiomyocyte damage. |
| 33166683 | To date, thousands of cases of infection are reported worldwide. |
| 33166999 | Despite this, only a handful of functionally-conserved coronavirus structural RNA elements have been identified to date. |
| 33167401 | Our main objective is to present the current most up-to-date progress in some clinical trials registered at ClinicalTrials.gov. |
| 33167921 | Date of registration: 23 November 2018. |
| 33168456 | No specific antiviral drugs are available for the treatment of COVID-19 till date. |
| 33169056 | Additionally, available literature pertinent to this topic is explored, assessment of the work to date is presented, and suggestions are provided regarding future directions related to online graduate medical education. |
| 33169599 | The pandemic of COVID-19 has emerged as a serious health crisis globally and India too has been extensively affected with 604,641 active cases reported, till date. |
| 33170094 | Because of the recency of the pandemic, few examples of COVID-19 contact-tracing models have been shared among local, state, and federal public health officials to date. |
| 33170150 | To date, there is no model to predict the severity of COVID-19 in elderly patients. |
| 33170333 | Date of final follow-up was July 17, 2020. |
| 33170448 | Since its outbreak in December 2019 in Wuhan, China, there are no medicines to cure the disease till date. |
| 33170741 | To date, however, the wide range of incompatible approaches taken to developing and reporting HEM estimates has limited their comparability and usefulness to policymakers. |
| 33170800 | The meta-analysis will be completed within 2 months of the start date. |
| 33170802 | Individuals with arthritis use Twitter to communicate with peers, and to receive up-to-date information from health professionals and services about novel therapies and management techniques. |
| 33172223 | To date, there have only been a few reports of reinfections in COVID-19 patients. |
| 33173127 | Furthermore, our long term simulations forecast the optimal date to end the policy. |
| 33173852 | The proper vaccine for COVID-19 is not available till date. |
| 33174388 | To date, there remains a paucity of high-quality evidence to inform clinical practice world-wide. |
| 33175700 | They were designed to minimize the risk of contagion were thus based on the fact that during that phase of SARS-COV-2 virus pandemic (COVID-19) and in the absence of an effective vaccine, the zero-contagion risk did not exist and does not exist to date. |
| 33175703 | To better understand the epidemics in different areas, the progress percentage was generated in this study by dividing everyday total confirmed case number by the up-to-date total case number, so data obtained from different countries and territories can be put together and compared directly regardless of the large difference in the magnitude of numbers. |
| 33175894 | Despite the profound health and economic implications of Covid-19, there is only limited knowledge to date about the role of economic concerns, health worries and social distancing for mental health outcomes during the pandemic. |
| 33176215 | However, the presence of SARS-CoV-2 has not been detected in the human eye to date. |
| 33176598 | We investigated the presence of SARS-CoV-2 receptor-binding domain (RBD)-specific antibodies in blood samples of 959 asymptomatic individuals enrolled in a prospective lung cancer screening trial between September 2019 and March 2020 to track the date of onset, frequency, and temporal and geographic variations across the Italian regions. |
| 33176850 | IRCT registration number: IRCT20091201002804N12 Registration date: 1st June 2020, 1399/03/12 FULL PROTOCOL: The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). |
| 33176886 | First recruitment: June 29, 2020 Estimated date for last recruitment: December 31, 2020 TRIAL REGISTRATION: Responsible Party: University of Sao Paulo General Hospital (Hospital das Clinicas) ClinicalTrials.gov Identifier: NCT04487990 , registered July 27, 2020, ReBec www.ensaiosclinicos.gov.br/rg/RBR-45kf9p/ Other Study ID Numbers: U1111-1252-0194 FULL PROTOCOL: The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1) In the interest in expediting dissemination of this material, the familiar formatting has been eliminated; this Letter serves as a summary of the key elements of the full protocol. |
| 33177251 | Hereafter, we define the date of delivery as Day 0 to make timeline clear. |
| 33178074 | To date, compliance of the Italian public with voluntary home quarantine has been very high, but little is known about the impact of psychological health on sociodemographic categories during the quarantine. |
| 33178237 | Despite the previous positive reports of plant-based medications, no successful clinical trials of phyto-anti-COVID drugs could be conducted to date. |
| 33178771 | More than 26,760,000 cases of SARS-CoV-2 infection have been reported globally to date. |
| 33178783 | PRoVENT-COVID will be the largest observational study to date, with high density ventilatory data and major outcomes. |
| 33179039 | These goals to date have been met. |
| 33180097 | The final date of follow-up was September 19, 2020. |
| 33180431 | The first Covid-19 case of the Republic of Turkey was seen March 10, 2020, which was determined as the threshold date for comparisons. |
| 33181320 | In this retrospective multicenter study, we included 782 patients (males, 56 %; median age 46) with confirmed COVID-19 from 54 hospitals in nine provinces of China, who were divided into four groups according to the treatment initiation time from the first date of onset of symptoms to the date of starting treatment with QFPDD. |
| 33181698 | This ongoing meta-analysis will provide up-to-date evidence of the efficacy of moxibustion for patients with COVID-19. |
| 33183205 | To date, various therapeutic approaches has been proposed and are being implemented to combat this pandemic, but unfortunately, no sovereign remedy has been es-tablished yet. |
| 33183207 | All evidence available to date on this topic is discussed in this review. |
| 33183366 | Models using numerical date, contemporaneous and distributed lag CMR data were contrasted using Bayesian Information Criteria. |
| 33184173 | To date, type VI, characterized by the four signature SNVs C241T (5’UTR), C3037T (nsp3 F924F), C14408T (nsp12 P4715L), and A23403G (Spike D614G), with strong allelic associations, has become the dominant type. |
| 33184280 | This up-to-date O-D flow open data can support many other social sensing and transportation applications. |
| 33184504 | To date, of all the respiratory viruses including influenza and coronaviruses, only influenza has had a drug (i.e., Tamiflu) specifically targeted to treat and prevent infection. |
| 33185036 | To date, the contribution of macrothrombi, i.e. visible thrombi in pulmonary arteries, to the death of patients with influenza A in comparison to COVID-19 remains unaddressed. […] We compare these results with influenza A autopsies from 2009 to 2020, other influenza A autopsy series and all COVID-19 autopsies published to date. |
| 33185145 | A search of the literature identified only twenty-five mechanistic models of bat-virus systems published to date, derived from twenty-three original studies. |
| 33185147 | We test whether European countries or US states who experienced their first death from COVID-19 at a later date have fewer deaths from COVID Â 60Â and 100 days after the start of the pandemic in their borders. |
| 33185365 | The final date of the follow-up was April 18. |
| 33186212 | To date, no certificated drug or vaccine has been developed for the treatment or prevention of coronavirus disease Extensive researches and international coordination has been conducted to rapidly develop novel vaccines against SARS-CoV-2 pandemic. |
| 33186229 | Evidence to date does not suggest that people living with HIV (PLWH) have a markedly higher susceptibility to SARS-CoV-2 infection, with disparities in the social determinants of health and comorbidities likely having a greater influence. |
| 33186406 | Quantitative fit-testing (QNFT) data from these stop-gap devices has not been published to date. |
| 33188620 | To date, we do not dispose of enough data to speculate about the risk of COVID-19 among immunocompromised patients, although in our SSc patients their frailty seems to have been their shelter. |
| 33188764 | However, no paper has been published up to date indicating how this virus could be quantified in soil samples. |
| 33188933 | Pooling all studies to date shows that on average 10% of patients with coronavirus infections might be missed with PCR tests. |
| 33189639 | To date, results of numerous studies have been shown that mesenchymal stem cells and their derivatives can suppress inflammation. |
| 33189768 | To date, no effective vaccines or therapies are available against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pandemic agent of the coronavirus disease 2019 (COVID-19). |
| 33190021 | The primary endpoint was 30-day all-cause mortality from the date of confirmed COVID-19. |
| 33190387 | The underlying mechanisms are to date controversial. |
| 33190456 | The present research explored the psychological implications associated with COVID-19 during the outbreak in 2020 to date. |
| 33191126 | Collating recommendations and keeping up-to-date with the latest guidance can help clinicians provide the best possible care to pregnant women and their babies. |
| 33191247 | Moreover, there have been limited evaluations to date of the impact of these sociodemographic factors on the use of telephone versus video visits. |
| 33192697 | Accurate and up-to-date health information should be disseminated to distressed and vulnerable subpopulations, perhaps using digital health technology, and social media platforms to prompt professional help-seeking behavior. |
| 33192820 | To date, it is not clear how compliant the Italian public has been with voluntary home quarantine, neither which factors have influenced an individual’s decision to comply with a quarantine order. |
| 33194438 | The results are compared with the so-called reactive strategy, which consists of isolating regions ordered by the date the first case of COVID-19 appeared. |
| 33194912 | This is the largest series of COVID-19 neonatal cases in Spain published to date. |
| 33195880 | We collected data on person (socio-demographics, circumstances of travel/contact, clinical and laboratory), time (date/period of reported exposures; laboratory confirmation and death) and place (location). |
| 33196056 | Integrated, up-to-date data about SARS-CoV-2 and COVID-19 is crucial for the ongoing response to the COVID-19 pandemic by the biomedical research community. |
| 33197765 | To date, the SARS-CoV-2 spread has already become a global pandemic with a considerable death toll. |
| 33198633 | Higher accuracy was associated with the availability of more data for estimation and with a more pronounced cumulative case growth from the first case to the date of estimation. |
| 33199180 | The data show that the pandemic in Brazil has grown rapidly since February 25th (date of the first reported case). |
| 33199278 | Responses to date have been highly variable and it is not clear whether public health guidance has been informed by the best available evidence. |
| 33199570 | Retrospective study comparing TBI incidence before and during COVID-19 pandemic era starting from the declaration of national pandemic date (March 16, 2020) until June 14, 2020 with the comparison of the same period in the previous year. |
| 33199941 | To date, the various transmission modes of SARS-CoV-2 have not been completely determined. |
| 33199975 | To date, the scale has been translated and validated in 19 other languages, among which Greek. |
| 33200026 | However, no effective treatment has been found for SARS-CoV-2 infection to date. |
| 33200069 | To date, there is no prescribed medicine for COVID-19. |
| 33200080 | Globally, approximately 2% of genomes, which to date could not be mapped to any distinct known cluster, fall within this clade. variants per site per year, which is lower than the prevalent A2a cluster. |
| 33200085 | Researchers are continuously searching for any possible cure and/or vaccine, but no conclusive report is available till date. |
| 33200093 | To date, few reports describe successful discharge from ECMO in COVID-19 after a prolonged ECMO run. |
| 33200304 | Remdesivir (RDV) has recently demonstrated promising results in adults with COVID-19, but few data have been reported to date in children.A nationwide multicenter observational study was conducted on children with confirmed SARS-CoV-2 receiving compassionate treatment with RDV in Spain. […] • Remdesivir has recently demonstrated promising results in adults with COVID-19, but few data have been reported to date in paediatric population. |
| 33201896 | The searches covered the period from the inception date of each database until April 28, 2020. |
| 33202421 | Seroprevalence estimates of anti-SARS-CoV-2 antibodies remain low to date, and the interpretability of serological testing and immunity remains undefined. |
| 33202656 | The rapid spread of the new Coronavirus Disease 2019 (COVID-19) has actually become the newest challenge for the healthcare system since, to date, there is not an effective treatment. |
| 33205222 | To date, hemorrhagic cutaneous manifestations reported are chilblain-like lesion, purpura to ecchymosis, livedo reticularis, and dry gangrene. |
| 33206207 | However, in vitro studies have to date failed to show a direct inhibition of famotidine on SARS-CoV-2 replication. receptor-mediated immunomodulatory actions on mast cell histamine-cytokine cross-talk, rather than a direct action on SARS-CoV-2. |
| 33206644 | The Islamic Republic of Iran reported its first COVID-19 cases by 19th February 2020, since then it has become one of the most affected countries, with more than 73,000 cases and 4,585 deaths to this date. |
| 33206721 | Using transit demand data derived from a widely used transit navigation app, we fit logistic functions to model the decline in daily demand and derive key parameters: base value, the apparent minimal level of demand and cliff and base points, representing the initial date when transit demand decline began and the final date when the decline rate attenuated. |
| 33207699 | To date, the present study provides the largest untargeted metabolomics and lipidomics analysis of plasma from COVID-19 patients and control groups, identifying new mechanisms associated with the host response to COVID-19, potential plasma biomarkers, and therapeutic targets. |
| 33208083 | In this review, we reported our multi-disciplinary team experience with up to date literature guidance to propose a valid protocol for management of COVID-19 patients in limited resources setting. |
| 33209137 | To date, several therapeutic agents have been studied or are currently examined, such as hydroxychloroquine, chloroquine, ritonavir/lopinavir, remdesivir, colchicines and interleukin-6 inhibitors. |
| 33210447 | Till to date, we do not have any specific medicine and/or vaccine to treat COVID-19; however, research is still going on at war footing. |
| 33210457 | Up to the date of writing this review (19 May 2020), there is one finished randomized clinical trial and two completed non-randomized studies, in addition to some ongoing studies, including three observational studies, two expanded access studies, and seven active clinical trials registered on the clinicaltrials.gov and isrctn.com websites. |
| 33211737 | Patient characteristics (age, gender, comorbidities), symptoms, date of symptom onset, RT-PCR results, imaging results of CT and leg ultrasound, laboratory findings (C-reactive protein, differential blood count, troponine, N-terminal pro-B-type natriuretic peptide (NT-proBNP), fibrinogen, interleukin-6, D-dimer, lactate dehydrogenase (LDH), creatine kinase (CK), creatine kinase muscle-brain (CKmb) and lactate,) and patient outcome (positive: discharge or treatment on normal ward; negative: treatment on intensive care unit (ICU), need for mechanical ventilation, extracorporeal membrane oxygenation (ECMO), or death) were analyzed. |
| 33211797 | To our knowledge, this study provides the most comprehensive multivariable analysis of county-level predictors of rates of COVID-19 cases and deaths conducted to date. |
| 33213322 | No effective therapy has been approved to date for the prevention or treatment of this disease, suggesting the need to broaden the scope in the search for effective treatments. |
| 33213323 | To date, more than thirty animals were tested positive for SARS-CoV-2, all of them infected by humans with COVID-19. |
| 33213379 | No specific therapies nor vaccine have been developed to date and the only way to limit the virus diffusion is by modifying one’s lifestyle limiting social life and following strict hygienic precautions. |
| 33213529 | Given the uncertainty of the pandemic, it is difficult to predict the anticipated end date. , 2020 (ClinicalTrials.gov Identifier: NCT04382755 ) and on EudraCT (Identifier: 2020-002130-33 ). |
| 33214421 | Subgroup analysis by geographical region and date of publication revealed variations over both time and geography in calculated R0 and Rt values. |
| 33214905 | Evidence to date has been about broad shifts in unemployment rates as a percent of the labor force. |
| 33215120 | To date, no studies have evaluated the mental health impact of these changes on the T&O workforce. |
| 33215154 | All orthopaedic trauma cases at the Wrightington Wigan and Leigh NHS Foundation Trust from ‘lockdown’ (23 March 2020) to date (15 June 2020) were collated and split into three groups. |
| 33215765 | Estimates for the number of present-day infections that will, at a later date, prove to be fatal are derived through a nowcasting model, which relates the day of death of each deceased patient to the corresponding day of registration of the infection. |
| 33216852 | The only drug to date to show a mortality benefit for COVID-19 in a randomized control trial is dexamethasone, but there remains uncertainty about which patients may benefit most and longer-term complications including secondary infections. |
| 33217545 | The purpose of this article is to review the most up-to-date published data regarding both the leading pharmacological therapies undergoing clinical trials and vaccine candidates in development to stem the threat of COVID-19. |
| 33217916 | COVID-19, a global pandemic causing to date more than 50 million cases and more than a million deaths, has to be controlled. |
| 33218946 | Stroke occurs in up to 6% of all patients with COVID-19, a figure that becomes significant given the large number of patients diagnosed to date. |
| 33219013 | The document has not been needed to date, nor adopted as hospital policy. |
| 33220155 | The date, title, source, type of advice and link to the advice were recorded in Excel. |
| 33220366 | We review the 42 cases of psychosis reported in infected patients to date, and discuss the potential implications of in utero infection on subsequent neurodevelopment and psychiatric risk. |
| 33220442 | To date, Vietnam is one of the few countries that have successfully control the spread of COVID-19. […] Early policy interventions were the main factors that contributed to the success of Vietnam to date. |
| 33221457 | To date, there are hundreds of herbal TCM formulae developed for the purpose of prevention and treatment during epidemic infections. |
| 33221922 | Striving to keep data up-to-date, new updates to gene annotations include GENCODE Genes, NCBI RefSeq Genes, and Ensembl Genes. |
| 33222515 | The recent pandemic has posed perhaps the biggest challenge for PCR to date. |
| 33223376 | Up-to-date data released by major health organizations such as the World Health Organization and major orthodontic associations involved in the pandemic were also evaluated. |
| 33223467 | Reported rates of acute kidney injury (AKI) have varied significantly among studies of coronavirus disease 2019 (COVID-19) published to date. |
| 33223590 | Reports to date have shown that the SARS-CoV-2 pandemic may have a negative impact on individuals’ mental health. |
| 33224361 | To date, real-time reverse transcription-polymerase chain reaction (RT-PCR) has been recognized as the diagnostic criterion for COVID-19. |
| 33225036 | To date, it remains unclear if severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) co-infection exacerbates liver injury in patients with chronic hepatitis B virus (HBV) infection. |
| 33225287 | A cross-sectional study of consecutive adult (> 13 years) patients with musculoskeletal trauma referred as either in-patients or out-patients over a 40-day period beginning on 5 March 2020, the date of the first reported UK COVID-19 death, was performed. |
| 33225363 | The study period was from 17 March (the date of first incident case in the healthcare system) to 6 May (the date Massachusetts implemented public masking). |
| 33225945 | Our primary exposure was the time between the date of the first reported case of COVID-19 to an implemented stay-at-home mandate for each region. |
| 33225948 | This study provides researchers and clinicians with a greater knowledge of the characteristics of articles that been published globally at the intersection of COVID-19 and TICAM to date. |
| 33225958 | We amplified partial RdRP gene, a stable genetic marker of coronaviruses, from a collection of 57 clinical specimens positive for SARS-CoV-2 or other human coronaviruses, and sequenced the amplicons with Nanopore Flongle and MinION, the fastest and the most scalable massively-parallel sequencing platforms to-date. |
| 33225995 | The estimated date for the end of the extended recruitment period is Feb 1, 2021. |
| 33227044 | To date of paper submission, it has very favorable course. |
| 33227069 | After providing mental healthcare, each volunteer completed an online form to record relevant consultation data provided with a total of 6800 interventions to date. |
| 33227071 | Since the start of COVID-19 till date, almost one-third of the world’s population is under some degree of restriction and lockdown, and the mental health effect of which is something that is being discussed widely. |
| 33227700 | More than 200 compounds have been screened and till date approximately 69 therapeutic agents are undergoing clinical trials across the world. |
| 33227708 | To date, there is no approved effective treatment or vaccine available to control the coronavirus disease-2019 (COVID-19). |
| 33229457 | Herein, experiences to date with telehealth usage for oncology care are reviewed, and priorities are outlined for postpandemic opportunities to improve the lives of patients with cancer through telemedicine. |
| 33230386 | To virtually screen various drugs against SARS-CoV-2, the scientists need the detail information about the various drug targets identified till date. |
| 33230404 | No definitive treatment or vaccine has been officially approved to-date. |
| 33230627 | It was detected initially in Wuhan, China and has spread rapidly to more than 208 countries to date. |
| 33231483 | Over 28 million confirmed cases of COVID-19 have been reported to date, resulting in over 900 000 deaths. |
| 33233013 | As far as these authors are aware, orthopaedic physical examination of the knee joint, including trauma work-up, has not been the subject of any studies to date. |
| 33233987 | To date, 14 patients have been placed on ECMO support at an outside facility and successfully transported via helicopter to our hub hospital using this protocol. |
| 33234660 | Of 14 150 patients included in CHESS until 13 May 2020, 401 lacked a confirmed diagnosis of COVID-19 and 7666 lacked a recorded date of symptom onset. |
| 33235142 | We present a case of an adolescent female with B-cell acute lymphoblastic leukemia hospitalized multiple times for symptomatic SARS-CoV-2 infection who was safely treated with 2 courses of remdesivir (RDV) and has had no additional readmissions to date. |
| 33235833 | This article presents a concise and up-to-date review focusing on its mechanisms of action and indications. |
| 33236131 | To date, remdesivir has been granted emergency use authorization for use in the management of infection. |
| 33238927 | To date, there are limited studies that have investigated the impact of COVID-19 pandemic on mental health among female population. |
| 33239100 | Date of first patient enrolled: 25.05.2020. […] Patients enrolled to date: 20 in total. 8 with confirmed COVID-19 infection and 12 with other infections. |
| 33239571 | In this article, the Association of Public Health Laboratories and a subset of its members examine the response to date and evaluate lessons learned from 4 main categories: testing surges, supplies, staffing, and regulations and policy. |
| 33239633 | Here, we formally test whether any homoplasies observed in SARS-CoV-2 to date are significantly associated with increased viral transmission. |
| 33240167 | The COVID-19 quarantine has affected more than 860 million children and adolescents worldwide, but to date, no study has been developed within Western countries to examine the psychological impact on their lives. |
| 33240557 | For those who accessed for orthopedic reasons, the analyzed variables included the date of ED admission, age, gender, after visit discharge or hospitalization, place where the injury occurred, traumatic mechanism, diagnosis, relationship with sport activity, and time from injury/symptoms debut to ED access. |
| 33240957 | To date, the direct and indirect consequences of the pandemic have been substantial including restrictions on agricultural workers, planting, current and future harvests; shifts in agricultural livelihoods and food availability; food safety; plant and animal health and animal welfare; human nutrition and health; along with changes in public policies. |
| 33241766 | A number of studies to date, however, have focused on ventilation in medical facilities (e.g. hospitals) as the risk of transmission of SARS-CoV-2 is higher there (because of the close proximity of workers to patients who have the disease and their treatment procedures). |
| 33242596 | To date, Sweden has reported higher case counts and attributable mortality than other Scandinavian countries and lower than other Northern European countries. |
| 33242791 | Recently, the novel coronavirus disease 2019 (COVID-19) has grown to be a global public health emergency but no effective drug is available to date. |
| 33243356 | The epidemic curve was represented by date of testing. |
| 33243817 | We will include all women in Scotland, UK, who were pregnant on or became pregnant after, 1 March 2020 (the date of the first confirmed case of SARS-CoV-2 infection in Scotland) and all births in Scotland from 1 March 2020 onwards. |
| 33244256 | Data, to date, has combined outcomes from medical and intensive care cohorts, or looked exclusively at intensive care. |
| 33244376 | The coronavirus disease (Covid-19) has caused a pandemic with more than 600,000 deaths to date. |
| 33244856 | To date, it is still not unanimously clear which effects parameters of virus and host are important for the development of severe disease course. |
| 33245704 | With no definitive treatment to date, prevention is critical, and strengthening the immune system is a valuable tool in reducing the risk of infection. |
| 33246271 | To date, the majority of chest imaging studies in COVID-19 pneumonia have focused on CT. |
| 33246296 | From our analysis of the available studies to date, it appears that a relationship is emerging in regard to patients with a smoking history having a higher likelihood of developing more severe symptoms of COVID-19 disease than non-smokers. |
| 33246674 | A website and a Facebook page were launched in Malta in March 2020 to disseminate accurate and up-to-date general information and the latest scientific developments vis-à-vis the COVID-19 pandemic. |
| 33247638 | Baseline data included demographics, prophylaxis regimen (including “no prophylaxis”) and start date. |
| 33249285 | To date, several studies revealed the beneficial effects of HPC in ischemia, kidney failure, and in pulmonary function recovery of patients who underwent lung surgery. |
| 33249407 | Participants (n=3207, aged 2-90 years), enrolled from a previously established nationwide serosurveillance study, provided a self-collected fingerstick blood sample and completed a questionnaire (median inclusion date 3 April 2020). |
| 33249673 | To date, SPMs have not been studied in the context of the novel Coronavirus, severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2), however their preclinical efficacy in combatting infections and improving acute respiratory distress suggest they may be a valuable resource in the fight against Coronavirus disease-19 (COVID-19). |
| 33250818 | Although a strong psychological impact is possible, scant evidence is available to date. |
| 33251158 | Apart from its diagnostic ability, CRISPR-Cas system is also being assessed for antiviral therapy development; however, till date, no CRISPR-based therapy has been approved for human use. |
| 33253058 | Although the genome, named CU_S3, belongs to the prevalent global genotype, marked by the D614G spike variation, the combined variations in the spike proteins and ORF1a do not co-occur in any of the 197,000 genomes reported to date. |
| 33253455 | From the evidence available to date, direct risks to the foetus from the SARS-CoV-2 virus are low. |
| 33254560 | To date however, there is no clear explanation how the viruses arrive form the face into the nose and the lung. |
| 33254561 | Till date, there is no clinically approved vaccine or drug for the treatment of COVID-19, and the ongoing search to find a novel therapy is progressing at pandemic pace. |
| 33254564 | To date, the spread of SARS-CoV-2 infection is increasing worldwide and represents a primary healthcare emergency. |
| 33254928 | Since no specific vaccines or drugs have been developed till date for the treatment of SARS-CoV-2 infection, early diagnosis is essential to further combat this pandemic. |
| 33255751 | In this article, an up-to-date review of published evidence on modern surgical and radiation therapy treatment options is summarized, including currently recommended treatment modifications of both therapeutic approaches during the coronavirus disease 2019 pandemic. |
| 33257496 | We conducted a cohort study at Mass General Brigham in Boston, Massachusetts, of patients with RMD matched to up to five comparators by age, sex and COVID-19 diagnosis date (between 30 January 2020 and 16 July 2020) and followed until last encounter or 18 August 2020. |
| 33257622 | To date, research on viral shedding (VS), live virus isolation and infection status remains ongoing as scientists and clinicians attempt to better understand the coronavirus disease of 2019 (COVID-19) pandemic. |
| 33257910 | A total of 2113 members of two Facebook groups for coronavirus patients with persistent complaints in the Netherlands and Belgium, and from a panel of people who registered on a website of the Lung Foundation Netherlands, were assessed for demographics, pre-existing comorbidities, health status, date of symptoms onset, COVID-19 diagnosis, healthcare utilisation, and the presence of 29 symptoms at the time of the onset of symptoms (retrospectively) and at follow-up (mean±sd 79±17 days after symptoms onset). |
| 33258339 | As the literature search was conducted on March, any subsequent versions of these guidelines require an up-to-date literature review. |
| 33258903 | To date, Sarbecovirus surveillance has been almost entirely restricted to China. |
| 33259325 | We assessed the date (May 23) that the government declared a rescission of the state of emergency. […] Taking into consideration the number of infectious cases in the field, a date of 1 week later (May 30) would have been most effective. |
| 33259815 | We also describe the pathophysiologic mechanisms proposed to date and their possible association with these manifestations. |
| 33261847 | The virus SARS CoV-2, which causes the respiratory infection COVID-19, continues its spread across the world and to date has caused more than a million deaths. |
| 33262067 | With over 50 million cases and 1.2 million deaths around the world, to date, this pandemic represents the gravest global health crisis of our times. |
| 33262543 | Our results using historic data from 4 countries provide insights into on-going disease suppression measures, while visualisation of reported data provides up-to-date condition monitoring of the pandemic status. |
| 33262913 | To date, it is unknown whether all infected patients induce an adequate protective immune response or how long this effect remains. |
| 33262931 | To date, ground-breaking 3D printing technologies are used in automobile, aerospace, clothing, pharma, and biomedical industries by creating pre-requisite engineered and tailored end-user products reaching standard sets. |
| 33263073 | To date, no effective preventive or curative medical interventions exist against COVID-19, caused by Severe Acute Respiratory Syndrome corona virus 2 (SARS CoV-2). |
| 33263102 | While there are promising developments, to date, there is no available drug or vaccine, and researchers are working around the clock to develop a solution. |
| 33264056 | Consistent documentation of progress and data gaps from standardized reporting of methods utilized, sampling date, details of test results by specimen type, risk assessments, and symptoms can all be used strategically and provide incentives to governments and their partners to prioritize the development, detection, and response to outbreaks. |
| 33264345 | Despite tremendous efforts and resources spent worldwide trying to explore antiviral drugs, there is still no effective clinical treatment for COVID-19 to date. |
| 33264393 | All viruses described to date entirely rely on the protein synthesis machinery of the host cells to produce proteins required for their replication and spread. |
| 33264436 | To date, there are no specific antiviral drugs proven to be effective in treating SARS-CoV-2, requiring joint efforts from different research fronts to discover the best route of treatment. |
| 33264497 | To date, no high-frequency mutations were detected at the C-terminal domain of the S1 subunit in the S protein, where the receptor-binding domain (RBD) is located. |
| 33267785 | The outcomes of pregnancies included miscarriage, intrauterine fetal death (IUFD), preterm birth and live birth were assessed until the end date of the outcomes follow-up (November 10th 2020). |
| 33267873 | Data on calls received, including date and time, caller characteristics, questions and responses were recorded in a database designed for this purpose. |
| 33268103 | An exact date of close contact with someone in Wenzhou with confirmed or suspected COVID-19 infection from Wuhan (the second-generation confirmed cases) could be provided by 38 (36%) patients. |
| 33268419 | To date, no robust vaccine or treatment has been identified. |
| 33269260 | The websites of World Health Organization, Centers for Disease control and Prevention, and the Johns Hopkins Coronavirus Resource Center were reviewed to provide up to date numbers and infection control recommendations. |
| 33269271 | To date, no serious complications have been found during follow-up after discharge. |
| 33269412 | Human coronaviruses known to date, common throughout the world, are seven. |
| 33270662 | To date, the scale-free network has been adopted for modeling online communities in several studies. |
| 33270705 | We compared this intervention with some hypothetical ones, varying the starting date and also the population proportion that is released, breaking the confinement. |
| 33270782 | A piecewise regression analysis was conducted with mortality and cumulative incidence rates introduced as dependent variables and time interval (days from the 22nd of January to the date when 100 first cases were reported) as the main predictor. |
| 33271925 | To date multiple mAbs against SARS-CoV-2 proteins have been established, however, bigger sets of various antibodies will allow the detection and neutralization of SARS-CoV-2, even if the virus acquires novel mutations. |
| 33272175 | To date, no clinically approved vaccines and/or specific therapeutic drugs are available to prevent or treat the COVID-19. |
| 33272309 | Date of trial registration: 20 October 2020, retrospectively registered. |
| 33273592 | In China-Excluding-Hubei area within 7 days after the first public report, our model successfully and accurately predicted the long trend up to 40 days and the exact date of the outbreak peak. |
| 33274091 | In the face of COVID-19, a new disease with unclear maternal and fetal outcomes to date, a collaboration of care teams is essential to navigate through the challenging decisions made, including timing of delivery, treatment options, and administration of steroids. |
| 33274530 | To date, the strongest predictor for dying with COVID-19 is suffering from several chronic disorders prior to the viral infection. |
| 33274614 | To date (30/09/2020) no recombination of the virus has been documented in the human host, and very few insertions and deletions. |
| 33276770 | The majority of dental emergency encounters do not result in definitive treatment, rather patients often return to the dentist at a later date for that treatment. |
| 33276811 | The recruitment is ongoing, and the date recruitment was initiated in June 2020. […] The anticipated date of the end of data collection is June 2021. […] The date of trial registration is 10 March 2020. |
| 33277291 | Patients diagnosed with COVID-19 from 22 February 2020 to 17 May 2020 were followed from date of diagnosis until outcome of interest, death or 17 May 2020. |
| 33279418 | It is difficult to argue with triage of medical care and resources in the face of anticipated overwhelming demand, but this situation resulted in considerable distress, as shown by a change.org petition opposing ASRM recommendations, which has gathered over 21,000 signatures to date. |
| 33279653 | We observed that the delay from the date of lockdown relaxation to the start of the second wave increases as lockdown is extended farther after the first wave peak-this delay is longer if lockdown is relaxed gradually. |
| 33280595 | Despite, to date, no certified antiviral treatment or vaccine prevails. |
| 33280767 | To date, all patients reported with venous thromboembolic disease and COVID-19 have shown evidence of viral pneumonia. |
| 33281245 | We analyse an interesting focal point as to how conferences in the area of Computer Science have reacted to this disruption with respect to their mode of offering and registration prices, and whether their response is contingent upon specific factors such as where the conference was to be hosted, its ranking, its publisher or its original scheduled date. |
| 33281306 | There is no clear date yet on when it will end. […] Then the distribution of the data was examined using the most up-to-date Covid-19 weekly case data and its parameters were obtained according to the statistical distributions. |
| 33281941 | While data profiling the gut microbiome in COVID-19 infection to date are limited, they support the possibility of several routes of interaction between COVID-19, the gut microbiome, angiotensin converting enzyme 2 (ACE-2) expression in the small bowel and colon and gut inflammation. |
| 33282058 | The coronavirus infection (COVID-19) to date has no vaccine or effective treatment. |
| 33282072 | Viral shedding duration was defined as the date of return from the COVID-19 pandemic countries for imported cases and from the first positive RT-PCR test for local cases, up to the second negative nasopharyngeal RT-PCR swab. |
| 33282166 | To date, there are no studies that report on the risk of infection among patients with haematological diseases or abnormalities. |
| 33282284 | To date, clinical evidence and guidelines based on reliable data and randomized clinical trials (RCTs) for the treatment of COVID-19 are lacking. |
| 33282586 | To date, several studies have suggested a severe acute respiratory syndrome coronavirus 2 (SARS-CoV2)-mediated hypercoagulability in the forms of pulmonary embolism, stroke, gangrene, “COVID toes,” as well as other acute thrombotic complications, warranting the use of systemic anticoagulation. |
| 33284848 | Articles in English evaluating the effectiveness of VI were included, without applying any date limits. |
| 33287245 | This review begins with an overview of SARS-CoV-2 morphology and replication and summarizes what is known to date about the detection of the virus in nasal, oropharyngeal, and fecal specimens of patients who have recovered from COVID-19, with a focus on the factors thought to contribute to prolonged detection. |
| 33287311 | Since the first patient identified with SARS-CoV-2 symptoms in December 2019, the trend of a spreading coronavirus disease 2019 (COVID-19) infection has remained to date. |
| 33287545 | Standard and practical approaches for COVID-19 management in surgical patients to date are not accessible, despite the magnitude of the pandemic. |
| 33289900 | Age-specific IFRs were computed using the prevalence data in conjunction with reported fatalities 4 weeks after the midpoint date of the study, reflecting typical lags in fatalities and reporting. |
| 33290245 | To date, 58 participants have been recruited (intervention group: n=35; control group: n=23). |
| 33290247 | In both the lockdown and nonlockdown groups, we calculated SWB indicators during the 2 weeks before and after the enforcement date of the residential lockdown using individuals’ original posts on Sina Weibo. |
| 33290402 | To date there is emerging evidence to provide effectiveness and compliance to intervention measures on COVID-19 due to rapid spread of the disease. […] In the study, we systematically searched the literature on community interventions to mitigate COVID-19, SARS (severe acute respiratory syndrome), H1N1 Influenza and MERS (middle east respiratory syndrome) epidemics in PubMed, Google Scholar, World Health Organization (WHO), MEDRXIV and Google from their inception until May 30, 2020 for up-to-date published and grey resources. |
| 33292147 | To date, there is no specific antiviral treatment against this virus. |
| 33292746 | To date, China has continued to implement actions to control any resurgence of new cases of COVID-19 and keep its population safe. |
| 33292755 | Non-randomized and modeling articles published to date in areas of COVID prevention with contact tracing, screening, quarantine, and isolation were included. |
| 33293100 | Hospital surge capacity is to date hardly quantifiable and often has to face physical limitations (material, personnel, spaces). |
| 33293664 | Older adults subjects > 60 years of age account for > 95% of the over one million fatal cases reported to date. |
| 33294485 | = 0.9953) and the lowest root mean squared error (RMSE = 8827); and second, predicting a probable end date found to be around the end of December 2020 with a projected number of 378,299 at the end of the outbreak. |
| 33294906 | In New South Wales (NSW), the most populous state in Australia, COVID-19 case numbers have to date been relatively low. |
| 33295957 | To date, no study has characterized the mucocutaneous features seen in hospitalized children with multisystem inflammatory syndrome in children (MIS-C) or the temporal association of these findings with the onset of systemic symptoms. |
| 33296419 | The final date of follow-up was May 1, 2020. |
| 33297491 | The evidence to date indicates that oral vitamin C (2-8 g/day) may reduce the incidence and duration of respiratory infections and intravenous vitamin C (6-24 g/day) has been shown to reduce mortality, intensive care unit (ICU) and hospital stays, and time on mechanical ventilation for severe respiratory infections. |
| 33298023 | Hence, key approaches to reducing these concerns require changes to the reality of their situation, and are likely to include (1) helping people optimise their health, limit risk of infection, and access necessities; (2) minimising the negative experience of disease where possible, (3) providing up-to-date, accurate and consistent information, (4) improving the government and healthcare response. |
| 33298196 | The study suggested that half of the respondents suffered from at least one symptom of psychological distress whereas 32% suffered from two or more symptoms of psychological distress such as restlessness, fearfulness, anxiety and worry and sadness in the past 2 weeks preceding the survey date. |
| 33298761 | Medical charts were reviewed for the date of admission, past medical history, and demographic variables, presenting signs and symptoms, admitting laboratory values, diagnostic imaging, diagnosis, treatment modalities, and outcomes including length of stay and disease severity. |
| 33298894 | Here, we retrospectively analyze 851 SARS-CoV-2-positive patients with at least two positive PCR tests and find that 99 of these patients remain SARS-CoV-2-positive after 4 weeks from their initial diagnosis date. […] Among 104 patients with an IgG test result, 90 patients were seropositive to date, with mean upper bound of time to seropositivity from initial diagnosis being 37.8 days (95% CI: 34.3-41.3). |
| 33301247 | The review ensures up-to-date data on surgical management of cancer patients under the pandemic, recommendations for resuming the elective surgery, preoperative screening and prevention of COVID-19. […] To date, the COVID-19 pandemic is still not resolved, and infection continues spreading around the world. […] To date, the recommendations for optimal surgical management of cancer patients within the pandemic are still actively developed considering the benefits of treatment and risks of SARS-CoV-2 infection. |
| 33301418 | To date, reducing and tracking human movement during the COVID-19 pandemic has proven effective in limiting the spread of the virus. |
| 33302344 | Given the persistent rise in Covid-19 cases to date, efforts should be directed towards validating the therapeutic effectiveness of these identified small molecule inhibitors. |
| 33302976 | The anticipated study completion date is November 2021. |
| 33303188 | Based on the available scientific evidence, it is not clear to date what is the best therapeutic strategy for the treatment of COVID-19. |
| 33303255 | Given the unprecedented nature of these changes, and unknown outcomes to date, we advocate for a data-driven approach to guide future policy and practice recommendations regarding MOUD. |
| 33303516 | To date, only a few cases of COVID-19 have appeared in refugee camps, and whether feasible non-pharmaceutical interventions can prevent the spread of the SARS-CoV-2 virus in such settings remains untested. |
| 33304869 | To date, only few seroprevalence studies included children. |
| 33305456 | To date, an approved vaccine or treatment option of a preventive character to avoid severe courses of COVID-19 is still not available. |
| 33306333 | LitCovid is a curated literature hub for tracking up-to-date scientific data about the SARS-CoV-2. |
| 33306423 | To date, the transmission of Coronavirus Disease-2019 (COVID-19) is still uncontrollable with the fact that the numbers of confirmed and death cases are still increasing. |
| 33306735 | The variables used for analysis were date of admission, date of discharge, length of stay, age, sex and diagnosis. |
| 33306986 | The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to the coronavirus disease (COVID-19) outbreak that became a pandemic in 2020, causing more than 30 million infections and 1 million deaths to date. |
| 33307227 | Several strategies failed, to date, to fully alleviate this testing process (e.g. saliva sampling or antigen testing on nasopharyngeal samples). |
| 33308423 | Decisions about the continued need for control measures to contain the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rely on accurate and up-to-date information about the number of people testing positive for SARS-CoV-2 and risk factors for testing positive. |
| 33308503 | To date, we do not have high-level evidence to inform immunosuppression minimization strategies in infected transplant recipients. |
| 33308661 | Till date there is no promising drug and vaccine available to treat this deadly viral infection. |
| 33308911 | This study is the first to date to show what happens when an opportunistic disease that could affect anyone meets the American system of inequality and is powerfully shaped by it. |
| 33309261 | It is essential CR surgeons keep up to date with changes in guidance, so uniformity in practice can be maintained. |
| 33309578 | To date, 38 patients required hospitalization while 9 remained self-home quarantined and 14 died. |
| 33312229 | Diffuse alveolar damage (DAD) is the histopathological pattern commonly described in all the postmortem series up to date. |
| 33312379 | The associations of lockdown-date, and turning points of these trends were assessed. |
| 33313575 | Five electronic databases (CINAHL, Embase, Medline, PsycINFO and Global Health) were searched from database inception to date, using pre-defined search terms. |
| 33313582 | This study aimed to compile the up-to-date information about the methods and pharmacological agents used in the diagnosis and treatment of coronavirus disease 2019 (COVID-19) and examine the methods used in the treatment of COVID-19 in patients in the intensive care unit by reviewing the treatment guidelines published by national health authorities worldwide. […] The available information revealed that, given the size and scope of the pandemic, to date, there has been no scientifically proven effective medicine and vaccines against SARS-CoV-2. |
| 33314173 | To date, there is no definitive and specific treatments for coronavirus disease-19 (COVID-19) infection while drugs introduced are still in the clinical trial phase. |
| 33315163 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as the causative agent of the ongoing pandemic, has spread into more than 200 countries to date. |
| 33315687 | Guidance to date has relied on data from SARS-CoV-1 and MERS-CoV to guide practices on patient isolation and personal protective equipment (PPE) use. |
| 33316027 | To date, there are no studies that assist health professionals in adjusting the dose of these drugs. |
| 33316211 | We included all adults (aged ≥18 years) alive and in follow-up on Feb 1, 2020, and with at least 1 year of continuous registration with a general practitioner before this date. |
| 33317498 | To date, most research on the causes and correlates of obesity has focused on a small number of direct predictors of obesity rather than testing complex models that address the multifactorial nature of the origins of obesity in early development. |
| 33320823 | We targeted patients who had an in-person appointment date that fell in the first few weeks following the Michigan governor’s stay-at-home order, necessitating conversion to virtual visits or deferment of in-person care. |
| 33320904 | Cohorts of severely ill patients with COVID-19 have been described in several countries around the globe, but to date there have been few published reports from the United Kingdom (UK). |
| 33322939 | To date, public health organizations’ efforts to counter COVID-19 misinformation have focused on identifying and correcting false information on social media platforms. |
| 33323525 | To date, quantifying seasonality of the disease has been limited by scarce data and the difficulty of isolating climatological variables from other drivers of transmission in observational studies. |
| 33323550 | However, a vaccine or specific drug is absent up to this date and more attention has been focused on the use of convalescent plasma (CP). |
| 33324258 | To date, there is a paucity of information regarding the effect of COVID-19 or lockdown on mental disorders. |
| 33325240 | BP control was defined by the most recent BP reading within 24 months of the index date (January 1, 2020). |
| 33327566 | Here, we provide the most extensive study to date of the genomic epidemiology of SARS-CoV-2 in Italy covering the first wave of infection. |
| 33327940 | To date, very few nationwide studies addressing the way in which mental health services are addressing the current pandemics have been published. |
| 33328777 | However, to date, there has been no clear association of CAPS to COVID-19. |
| 33330528 | This review examines up-to-date information on ocular manifestation, laboratory testing, transmission, and prevention of COVID-19. |
| 33330675 | To date, little data is available about COVID-19 presentation, complications, and appropriate treatment in this population. |
| 33331649 | Prior transcriptomic studies of host cells in response to SARS-CoV-2 infection have not reported to date the effects of SARS-CoV-2 on the MVP. |
| 33332288 | To date, no specific antiviral treatment or vaccine for COVID-19 has been approved by the Food and Drug Administration (FDA). |
| 33332356 | This is the largest and most racially/ethnically diverse case series of patients tested and hospitalized for COVID-19 in New York City to date. |
| 33332418 | We used log-linear regression models to explore associations of cases and deaths with the BCG vaccination policy in each country, adjusted for population size, gross domestic product, proportion aged over 65 years, stringency level measures, testing levels, smoking proportion, and the time difference from date of reporting the 100th case to 31 May 2020. |
| 33333012 | Our aim is to provide definitions for clinical research and up-to-date recommendations for clinical management of the diagnosis and treatment of COVID-19-associated pulmonary aspergillosis. |
| 33333252 | The purpose of this study is to evaluate clinical outcomes in patients with critical COVID-19 pneumonia requiring invasive mechanical ventilation who were treated with tocilizumab DESIGN: Single-center retrospective cohort study SETTING: Stony Brook University Hospital, a 600-bed academic tertiary medical center in Suffolk County, New York PARTICIPANTS: Consecutive patients with COVID-19 confirmed by nasopharyngeal polymerase chain reaction (PCR) who were admitted to Stony Brook University Hospital between March 10 and April 2 2020 and required mechanical ventilation in any intensive care unit during their hospitalization EXPOSURE: Treatment with tocilizumab while intubated MAIN OUTCOME: Overall mortality 30 days from the date of intubation RESULTS: Forty-five patients received tocilizumab compared to seventy controls. |
| 33333255 | The virus originated in Wuhan, China, in December 2019 and has spread across the globe to-date. |
| 33333393 | COVID-19 is a public health emergency of international concern with millions confirmed cases globally including in Indonesia with more than two hundred thousand confirmed cases to date COVID-19. |
| 33333559 | To identify key gene expression pathways altered with infection of the novel coronavirus SARS-CoV-2, we performed the largest comparative genomic and transcriptomic analysis to date. |
| 33334050 | To date, there is no vaccine, and no specific antiviral medicine has been shown to be effective in preventing or treating COVID-19. |
| 33334338 | Real-time linkage of all sources per study could help to keep systematic reviews up-to-date. |
| 33334357 | The registration date is May 4, 2020. |
| 33334457 | To date, there is only randomized controlled trial evidence to support the use of dexamethasone in patients requiring oxygen therapy and remdesivir for shortening the time to recovery, with no specific treatment for COVID-19-associated AKI. |
| 33335769 | The 2019 novel coronavirus pandemic, severe acute respiratory syndrome CoV-2 (COVID-19), has been a worldwide urgent public health threat, resulting in six-hundred seventy thousand deaths to date. |
| 33335873 | The search included the data published from the date of the start of the pandemic in December 2019 up to October 2020. |
| 33336354 | For subgroup analyses the patients were divided according to the percentage of parenchymal opacification (0-33 %, 34-66 %, 67-100 %) and according to time interval between symptom onset and CT date (0-5 d, 6-10 d, 11-15 d, > 15 d). […] Radiologists should take into account the time interval between symptom onset and date of CT and the severity of disease when discussing the likelihood of COVID-19 pneumonia based on CT morphology. |
| 33337310 | Ontario families are required to provide up-to-date vaccination records as children begin schooling. |
| 33338078 | These were sex, age, ethnicity, date of the last ALRTI, number of ALRTIs in the last year, and treatments received. |
| 33339110 | The current COVID-19 pandemic has tested the resolve of the global community with more than 35 million infections worldwide and numbers increasing with no cure or vaccine available to date. |
| 33339696 | To date, health organizations and countries around the world are struggling to completely control the spread of the coronavirus disease 2019 (COVID-19). |
| 33340275 | However, due to the ever-changing state of understanding of COVID-19, all points discussed in this review may be out of date at the time of its publication. |
| 33340801 | To date, limited information exists about how Accountable Care Organizations (ACOs) are adapting to manage these patients. |
| 33341098 | The objective of this review is to provide an up-to-date overview of current mobile health applications (apps) that claim to assess hearing. |
| 33341155 | To date, influenza epidemics have been considered suitable for use as a model for the COVID-19 epidemic, given that they are respiratory diseases with similar modes of transmission. |
| 33341900 | Through enormous scientific effort, thousands of viral strains have been sequenced to date, thereby creating a strong background for deep bioinformatics studies of the SARS-CoV-2 genome. |
| 33342635 | This systematic review reports the largest number of children younger than five years with COVID-19 infection till date. |
| 33344621 | No COVID-19-specific drug has been reported to date, and symptomatic and optimal supportive care, including oxygenation, anti-coinfection treatments, and ventilation, represent the mainstay of treatment for this disease, especially in critical patients. |
| 33344792 | These symptoms could be mitigated by continuing the regular academic activities and delivering the most accurate up-to-date information on the COVID-19 through social networking sites. |
| 33347419 | Despite the pandemic, the development or actualization of medical guidelines, especially in the rapidly changing field of oncology, needs to be continued to provide up-to-date evidence- and consensus-based recommendations for shared decision making and maintaining the treatment quality for patients. |
| 33347846 | We searched MEDLINE(R) ALL (Ovid), CINAHL (EBSCO), PsycINFO (Ovid), Scopus, Sociological Abstracts (ProQuest), Embase and Embase Classic (Ovid), Emcare Nursing (Ovid), and AgeLine (EBSCO) for research that quantified an aspect of social connection among LTC residents; we limited searches to English-language articles published from database inception to search date (July 2019). |
| 33348065 | However, the inflammatory response in Corona virus disease-19 (Covid-19) and its potential to cause collateral organ damage has not been fully elucidated to date. |
| 33348315 | All patients undergoing PCI in England between January 1, 2017 and May 10, 2020 (n = 273,141) were retrospectively analyzed according to their outcome from the date of PCI: no death, in-hospital death, postdischarge death, and total 30-day death. |
| 33351863 | Till date, no completely effective drug or vaccine is available to cure COVID-19. |
| 33352098 | Turkey had 1,396 new cases, 194,511 total cases, and 5,065 deaths by the same date. |
| 33352298 | We reviewed the literature to date on COVID-19 in patients with SLE and provide an in-depth review of current research in the area, including immune pathway activation, epidemiology, clinical features, outcomes, and the psychosocial impact of the pandemic in those with autoimmune disease. |
| 33352330 | The data included the date of sampling, sex, age and the SARS-CoV-2 RT-PCR test result on specimens collected between 1 February and 15 June 2020. |
| 33352883 | As of the same date, Italy represents the third country worldwide in total number of cases and the first one in total number of deaths. |
| 33354578 | To date, no intervention is available to prevent COVID-19 and its manifestations. |
| 33354679 | The date of final follow-up was June 12, 2020 Two large, acute-care hospitals in Western Connecticut. |
| 33355053 | Although, considerable knowledge has been acquired with time about the viral mechanism of infection and mode of replication, yet no specific drugs or vaccines have been discovered against SARS-CoV-2, till date. |
| 33356684 | With a quick spread of the outbreak from its origin, Wuhan, China, to almost all over the world, it has affected more than seven million people to date, hence it has devastated every part of the infrastructural skeleton of governance. |
| 33357220 | Up-to-date data regarding the role of hydroxychloroquine (HCQ) and chloroquine (CQ) in COVID-19 have been summarized. |
| 33358057 | To date, approximately one million deaths and over 32 million cases have been reported. |
| 33358180 | This perspective discusses proposed and enacted state statutes, resolutions, and bills addressing college FI to date, which range in depth, breadth, and success. |
| 33358220 | This study presents the most extensive description, to date, on the clinical and demographic characteristics of COVID-19 patients in Nigeria. |
| 33359807 | All ORF3a mutations in the virus genomes were grouped according to the collection date interval and over the entire data set. |
| 33360242 | To date there is no data about the SARS-CoV-2 RNA detectability period in human bodies after death. |
| 33361342 | These challenges may help to explain why very few cases have been described to date. […] To provide context for future investigations of SARS-CoV-2 reinfection, we review 16 cases that have been published to date or are available in pre-print. |
| 33361753 | No date or language restrictions were applied. |
| 33361797 | To date, only a handful of studies have explored the emotional impact of the pandemic surrounding pregnancy and none have investigated the consequence of pandemic-related social restrictions on the postpartum mood of those living among different socioeconomic status (SES). |
| 33362233 | Only confirmed COVID-19 cases who are Vietnamese and locally infected with available data on date of symptom onset and clearly defined window of possible SARS-CoV-2 exposure were included. |
| 33362654 | Searches were restricted by date (2000 until present). |
| 33362758 | Up to the date, 42 prototypes are being tested in humans in different clinical stages, with 10 vaccine candidates undergoing evaluation in phase III clinical trials. |
| 33362916 | To date, no treatment has proved to be safe or effective. |
| 33363165 | To date, immunomodulatory therapies and supportive treatment are the predominant strategies. |
| 33363453 | During the COVID-19 pandemic from January 23, 2020, the date of lockdown of Wuhan, to April 30, 2020, 34 sessions of remote programming were conducted with 16 patients. |
| 33363932 | This is the first case of acquired severe neutropenia in the context of COVID-19 reported to date. |
| 33364675 | Overall, the evidence to date supports the notion that all connected hearing devices can improve accessibility to and affordability of amplification. |
| 33365070 | According to the recommendations of the International Health Regulations Emergency Committee and the facts and cases that 215 other countries have also reported to date, the World Health Organization Director-General announced that the outbreak of 2019-nCoV constitutes a public health emergency of international concern and a severe threat to the human health worldwide. […] To date, the prevalence of the virus has continued in waves and is increasing globally. |
| 33367597 | Coronaviruses (CoV) are positive-sense single-stranded RNA viruses, harboring the largest viral RNA genomes known to date. |
| 33367960 | Quantitative data was expressed in mean ± SD, while the qualitative date in percentages. |
| 33368777 | However, to date, recruiting and retaining COVID-19 convalescent plasma donors has been challenging. |
| 33369296 | This contrasts with the rest of the world, in which most residency exams were cancelled, even without a solution or an alternative date. |
| 33369568 | The WHO announced the coronavirus disease 2019 (COVID-19) outbreak as a pandemic in February 2020 with over 15 million confirmed cases of COVID-19 globally to date. |
| 33369903 | The first pandemic is new and to date substantial resources have been allocated to urgently addressing its mitigation; the second has a long history with inconsistent attention and resources but has recently been spotlighted more intensely than at any time in the nation’s recent past. |
| 33370015 | As additional information from clinical trials and from data collected on vaccinated pregnant persons becomes available, it will be critical for obstetricians to keep up to date with this information. |
| 33370173 | To date, only 1 randomized controlled trial has examined a community mask recommendation. |
| 33371042 | To date, no specific antivirus drugs or vaccines have been available to prevent or treat the COVID-19 pandemic. |
| 33371140 | Relevant randomised controlled trials(RCTS), controlled before and after, interrupted time series and prospective analytic cohort studies regardless of publication date, language and geographic location, will be included. |
| 33372427 | The mean serial interval before and after this fifth case definition was 6.12 and 3.93 days based on the infectors’ symptom onset date, respectively, and 4.02 days in total with the median of 3 days. |
| 33373808 | The novel coronavirus disease (COVID-19) poses mental health challenges globally; however, to date, there is limited community level data. |
| 33373874 | To date, no studies have analyzed the role played by the different dimensions of psychological distress quarantine-induced in patients with epilepsy. |
| 33375040 | There are no screening methods to date and a molecular biology platform is essential to perform RT-PCR for SARS-CoV-2; however, accessibility remains poor. |
| 33375194 | Few reports speculated about the prognostic implications of anticancer therapy, including immunotherapy, in lung cancer patients with concomitant Sars-Cov-2 infection, showing, to date, inconsistent results. |
| 33376052 | The document provides useful information about preventive measures in the practice of ultrasound in rheumatology in times of a COVID-19 pandemic based on the experience and literature available to date. |
| 33378367 | Follow up was done for the participants from the first date of diagnosis to the date of recovery (negative Real-time Reverse Transcriptase Polymerase Chain Reaction (rRT-PCT) test of throat swab). |
| 33380055 | Our results are in good agreement with the data to date and show that social distancing significantly reduces the epidemic spread and flattens the curve. |
| 33380341 | However to date, this integration remains inadequate, fragmented and under-funded, with limited reach and small initial investments. |
| 33380727 | The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has devastated global public health systems and economies, with over 52 million people infected, millions of jobs and businesses lost, and more than 1 million deaths recorded to date. |
| 33382348 | To date, proposed therapies and antiviral drugs have been failed to cure coronavirus disease 2019 (COVID-19) patients. |
| 33382676 | Among 185 household contacts enrolled, 109 (59%) had detectable SARS-CoV-2 at any time; 76% (83/109) of test results were positive within 7 days, and 86% (94 of 109) were positive within 10 days after the index patient’s illness onset date. |
| 33382764 | Assessment of the full range of evidence generated to date to understand the characteristics of the antibody response, its dynamics over time, its determinants and the immunity it confers will have a range of clinical and policy implications for this novel pathogen. |
| 33382773 | We conducted a retrospective study on patients admitted to the ICU with a diagnosis of COVID-19 between March 10 (i.e. the date of the first admitted patients) and April 30, 2020. |
| 33382903 | The impact of coronavirus disease 2019 (COVID-19) on patients listed for solid organ transplantation has not been systematically investigated to date. |
| 33383142 | To date, TCR bias has been observed in various diseases. |
| 33383190 | However, to date a specific regimen to treat COVID-19 is not available. |
| 33384142 | To date, little is known about the impact of COVID-19 on pregnancy. |
| 33384154 | We compared 30-day outcomes between COVID-19 positive and negative patients, and the effect of time from testing positive to the date of procedure (≤10 days, 11-30 days and >30 days) on outcomes. |
| 33384501 | What happens to the children with MIS-C, in the long run, remains unknown to date. |
| 33385021 | Although many studies have explored the neural mechanism of the feeling of stress, to date, no effort has been made to establish a model capable of predicting the feeling of stress at the individual level using the resting-state functional connectome. |
| 33385107 | Nevertheless, to date no specific suggestions regarding physical activity and exercise in cancer patients during the COVID-19 era have been released, neglecting the potential deleterious effects of quarantine and sedentary behaviour (imposed as containment measures against COVID-19), particularly in these subjects. |
| 33385178 | COVID-19 is the current day pandemic that has claimed around 1,054,604 lives globally till date. |
| 33388027 | We introduce Propedia, a comprehensive and up-to-date database with a web interface that permits clustering, searching and visualizing of protein-peptide complexes according to varied criteria. […] Propedia is up-to-date as a ready-to-use webserver with a friendly and resourceful interface and is available at: https://bioinfo.dcc.ufmg.br/propedia. |
| 33388249 | Nevertheless, the positive outcomes of the few case reports published to date suggest that convalescent plasma therapy may be of potential benefit. |
| 33388575 | Age, sex, comorbidities, symptom onset date, mortality, and specimen collection date were obtained from electronic medical records. |
| 33390384 | To date, a large number of COVID-19 vaccines are being rapidly developed worldwide, with thirteen candidates in Phase 3 trials, 52 tested in clinical trials, and 162 in preclinical evaluation. |
| 33390829 | China is regarded as one of the world’s leading countries in SARS-CoV-2 vaccine development, up to date the last inactivated vaccine international clinical (Phase III) trial was launched in the United Arab Emirates by Sinopharm China National Biotec Group (CNBG). |
| 33391099 | The present review includes an actualized to date bibliography, articles for which were methodologically analyzed to verify they met the standards of quality and scientific accuracy. |
| 33391129 | In this article we review the empirical basis of the approach within experimental, social, biological and clinical psychology, illustrate the novel and time-efficient delivery format, describe its relevance to sports and exercise, summarise feedback from the recipients of the intervention to date, and describe the directions for future evaluation. |
| 33391281 | Having a thorough understanding of the benefits and cautions of standardized serological testing at a community level remains critically important in the design and implementation of future vaccination campaigns, epidemiological models of immunity, and public health measures that rely heavily on up-to-date knowledge of transmission dynamics. |
| 33391888 | However, to date, there is no published effective and efficient method to titrate HCoVs other than expensive indirect immunostaining. |
| 33391929 | To date, there remains an unknown association between COVID-19 and causation of pneumomediastinum and pneumopericardium. |
| 33392261 | The 3CL protease (3CLpro) is the main protease of the SARS-CoV-2, which is responsible for the viral replication and therefore considered as an attractive drug target since to date there is no specific and effective vaccine available against this virus. |
| 33392360 | From the onset of initial symptoms, the total CT score peaked at an earlier date in the non-severe than the severe cases (13 days versus 15 days). |
| 33393278 | To date, there is a lack of findings on the role of rehabilitation in post-acute COVID-19 patients. |
| 33394296 | To assess problems faced by doctors and satisfaction of caregiver of patients with teleconsultation, a prospective questionnaire was sent via Google Forms 6-10 wk after the initial appointment date. |
| 33394354 | To date, not much is known about the outcomes of acute surgical diseases in this scenario. |
| 33394524 | To date, no data have been published concerning pain induced by conventional- or self-swabbing. |
| 33395031 | Patients were divided into three groups based on injury date: before SAH from 1/1/2020-3/18/2020 (PRE), after SAH from 3/19/2020-6/30/2020 (POST), and a historical control from 3/19/2019-6/30/2019 (CONTROL). |
| 33395080 | However, to-date, no harm has been proven for these drugs. |
| 33395100 | Over 70 million people worldwide, including those with neurodegenerative disease (NDD), have been diagnosed with coronavirus disease 2019 (COVID-19) to date. |
| 33397429 | The registration date is November 17, 2020. |
| 33397626 | However, to date, neither epidemiological data nor case reports of clear foodborne transmission of either viruses exist. |
| 33397903 | Serologic methods can more accurately estimate the disease burden by detecting infections missed by the limited testing performed to date. |
| 33398249 | With the data available until the 24st of March the peak date should be reached on May 3 (April 23 to May 23) with 197,179 cumulative infections expected (130,033-315,269); with data available until the 31st of March the peak should be reached on May 4 (April 25 to May 18) with 202,210 cumulative infections expected (155.235-270,737); with data available until the 07st of April the peak should be reached on May 3 (April 26 to May 11) with 191,586 (160,861-232,023) cumulative infections expected. |
| 33398362 | To date, multiple theories relating to the pure effects of renin-angiotensin-aldosterone system (RAAS) inhibitors on COVID-19 infections have been postulated. […] Up-to-date published data concerning the RAAS inhibitors and COVID-19 are summarized. |
| 33400393 | To date, many 3CLpro inhibitors have been reported, and their molecular mechanisms have been illustrated. |
| 33401078 | To date, there is no evidence to suggest specific pharmacological strategies. |
| 33402882 | The date of admission to hospital ranged from January 30 to February 19, 2020. |
| 33403180 | To our knowledge, to date, there has been only one case report of COVID-19 presenting as KD in an adult patient. |
| 33403201 | Through the 1339 hotline, callers received the up-to-date information that enabled them to protect themselves as well as others from COVID-19. |
| 33403981 | To date, the subcommittee has reviewed 14 potential treatments, and made recommendations based on local context, feasibility, resource requirements and equity. |
| 33403985 | Analysis was performed by age, sex, province, date of death and comorbidities. |
| 33404263 | To date, no specific drug in controlling this disease has been identified. |
| 33406478 | We also found an association between correct nasopharyngeal swab techniques and recency of video publication date (relative to May 15, 2020). |
| 33407321 | To date, there is no effective treatment for COVID-19, which is a pandemic disease, caused by a novel coronavirus called SARS-CoV-2. |
| 33407833 | To date, there are several reports on nosocomial outbreaks of SARS-CoV-2, and although the attack rate is variable, it can be as high as 60%, with high mortality. |
| 33408540 | Considering the date and dose coverage of last prescription, all patients due to refill this prescription for a chronic therapy in the last month were identified, and it was verified if they had the refill. |
| 33409021 | To date, the neurological symptoms of stuttering and word-finding difficulties have not been reported in confirmed COVID-19 cases. |
| 33410121 | To date, there has been little application of a race, migration and gender lens to explore the long-term health and social consequences of COVID-19 in African, Caribbean and Black (ACB) communities in Canada, who have been disproportionately impacted by this pandemic. |
| 33411700 | During May 8-November 16, VDH identified 8,798 exposed contacts of COVID-19 patients; 3,983 (45%) had sought testing within 14 days of their exposure, with day 0 defined as the date of last exposure noted in the case investigation record. |
| 33411805 | Statistical approaches were utilized to explore the difference and correlation for the seropositive rate of IgG and IgM antibody on the basis of sex, age group, geographic region and detection date. |
| 33412360 | To date the impact of these pandemic-related variations has yet to be fully understood also in the field of maternal health for which continuity of care is a proven life-saving preventive measure. |
| 33412793 | The RDt index does not take into account the time of infection, but the date of the diagnosis of positivity and for this reason it is defined as diagnostic replication index, as it aims to describe the intensity of the development of frequency for cases recognized as positive in the population.The comparison between different possible applications of the methods and the use of different types of monitoring data was limited to four areas for which complete individual data were available in March and April 2020. […] The main problems in the use of Rt, which is based on the date of symptoms onset, arise from the lack of completeness of this information due both to the difficulty in the recording and to the absence in asymptomatic subjects.The general trend of RDt, at least at an intermediate lag of 6 or 7 days, is very similar to that of Rt, as confirmed by the very high value of the correlation index between the two indices. |
| 33412802 | Finally, the resulting model was used to produce medium-long term projections of the epidemic dynamics. the date of the first infection in Tuscany was estimated as February 21st 2020. |
| 33413718 | Only studies in the UK on individuals dying from coronavirus disease 2019 (COVID-19) in hospital have been published, to date. […] Age, sex, date and place of death, occupation, comorbidities and where infection acquired was recorded for all deaths from COVID-19, between 6 April and 30 May, for whom an application was made for cremation at a South Wales’ crematorium. |
| 33414763 | To date, the incidence rate of spinal cord involvement in COVID-19 is not known and the pathogenesis is still not fully understood. |
| 33416859 | Yet, to date, there is no evidence of this disproportionate impact on non-national individuals, including economic migrants, short-term travellers and refugees. […] We found that, compared to Italian cases, non-Italian cases were diagnosed at a later date and were more likely to be hospitalized {[adjusted rate ratio (ARR)=1.39, 95% confidence interval (CI): 1.33-1.44]} and admitted to ICU (ARR=1.19, 95% CI: 1.07-1.32), with differences being more pronounced in those coming from countries with lower human development index (HDI). |
| 33417586 | To date, no studies have assessed China’s internet hospitals during the COVID-19 pandemic. |
| 33420507 | Referrals between March-August 2020 were analysed by date and industry to assess service utilization. |
| 33420914 | The challenges associated with imaging infected patients have resulted, to date, in a paucity of metabolic imaging studies of patients with severe COVID-19 infection. |
| 33421743 | However, till date there is no effective treatment found against SARS-CoV-2. |
| 33421866 | Mixed-effects logistic regression was used to examine the association between date and mental distress, stratified by resilience level (low, normal, or high). |
| 33422039 | The evidence to date suggests that female nurses with close contact with COVID-19 patients may have the most to gain from efforts aimed at supporting psychological well-being. |
| 33422901 | This study represents the largest study to date, that objectively analyzes the outcomes of COVID-19 positive patients who underwent surgery. |
| 33424059 | Yet, to date, no work has examined AS as a vulnerability factor for the negative mental health effects of COVID-19. |
| 33424145 | Till date, no specific validated medication is available for the treatment of COVID-19 patients. |
| 33425407 | To date, there are no studies and scant information in the literature evaluating remdesivir utilization in patients with eGFR less than 30 mL/min or receiving hemodialysis. |
| 33425654 | This review summarizes findings up to date on the relationship between cardiovascular disease (CVD) and COVID-19. |
| 33426009 | Data collected to-date suggest that ambient levels of both UVA and UVB may be beneficial for reducing severity or mortality due to COVID-19, with some inconsistent findings. |
| 33426593 | Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), a highly pathogenic member of family coronaviridae, has caused an exponentially growing global pandemic termed as the coronavirus disease 2019 (COVID-19) with more than 12 million cases worldwide till date. |
| 33427377 | To date, these analogues have not been documented in-depth as anti-human immunodeficiency virus (HIV) and anti-hepatitis virus agents, these are at various stages of testing ranging from pre-clinical, to those withdrawn from trials, or those that are approved as drugs. |
| 33428224 | A total of 69 participants have been enrolled to date. |
| 33428871 | To date, 750 000 patients with COVID-19 worldwide have required mechanical ventilation and thus are at high risk of acute brain dysfunction (coma and delirium). |
| 33429439 | For each case, symptoms, date of onset, date of testing and the last attendance at work were extracted. […] Out of 130 symptomatic COVID-19 cases, 42 (32.3%) attended the workplace after their reported date of symptom onset, including 16 (12.3%) with recorded COVID-19 symptoms. |
| 33429731 | The PubMed, EMBASE, ClinicalTrials.gov, Cochrane Library, China National Knowledge Infrastructure, and Wanfang databases were searched for randomized controlled studies published to date. |
| 33429732 | To determine whether anti-IL6 drugs are effective in improving prognosis and reducing hospitalization times and mortality in COVID-19 pneumonia.To date 84% (42/50) of IL6 group patients have already been discharged and only 2/50 are still recovered and intubated in intensive care. |
| 33430200 | To date, the need for further well-designed studies stating protocols and the efficacy/tolerability profile of IVIG and convalescent plasma in selected situations are awaited. |
| 33431109 | Studies were summarised into five main subcategories: potential impact of the COVID-19 pandemic on physical health outcomes of patients with schizophrenia spectrum disorders, impact on mental health outcomes, review of case reports and case series to date, treatment recommendation guidelines and risk of increased prevalence of psychosis. |
| 33431394 | To date, short-term funding and policy fixes for the coronavirus disease 2019 (COVID-19) pandemic have focused on saving the current health care system; policies have not maximized the population’s health, prioritized the safety net, nor addressed the fundamental problems that have hindered our nation’s response for our most vulnerable neighbors. |
| 33432606 | Since the beginning of the current pandemic our journal has published a series of important mechanistic and clinical reports of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection and Coronavirus Disease 2019 (COVID-19) aimed to keep our readership up-to-date on all relevant developments in this world-wide crisis (1). |
| 33433419 | Till date, SARS CoV2 (COVID-19) is a pandemic viral infection in the world with the main and strong impact on respiratory airway, but this virus can affect any system of the human body. |
| 33434096 | This article reports the results of the NIOSH testing to date and discusses how it has contributed to continuous improvement of the crisis strategy of temporarily permitting the use of non-NIOSH-approved respirators in US occupational settings during the COVID-19 pandemic. |
| 33434141 | However, research to date has mostly focused on initial adoption, with limited consideration of how video consulting can be mainstreamed and sustained. |
| 33434661 | We explored testing data through July 31, 2020, or most recently available, using case-indexing methods, which involve synchronizing countries by date of first reported COVID-19 case as an index date and normalizing to the cumulative tests 25 days post-index date. |
| 33437687 | To date, there are no specific vaccines or medicines for COVID-19; and treatments are under investigation through clinical trials. |
| 33437919 | To date, only rare cases of arterial thrombosis related to COVID-19 have been reported. |
| 33437921 | To date, this is the first case of COVID-19 complicated by IE. infection. |
| 33438054 | Comparative analysis of the number of publications in the PubMed® database concerning COVID-19 with respect to publication type, date and place of publication, affiliation to an institute of pathology, and correlation with the number of SARS-CoV‑2 infections over the same timeframe. |
| 33439316 | Each patient with a positive SARS-CoV-2 RT-PCR and a normal initial chest CT after second reading was 1:1 matched based on sex, age and date of CT acquisition to a patient with positive RT-PCR and initial chest CT with typical COVID-19 lesions. |
| 33439508 | Retrospective data were collected for 3 months from the date of transplantation or until study conclusion (5/7/2020). |
| 33439878 | While there is a growing number of studies looking at the performance of household materials against some of these situations, to date, there has not been any systematic characterization of household materials against all three modes. |
| 33440895 | This review discusses the different phases of vaccine development and the various platforms in use for candidate COVID-19 vaccines, including their progress to date. |
| 33442818 | To date, the risk/benefit balance of lockdown in controlling severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) epidemic is controversial. |
| 33444408 | Up to date, the underlying mechanisms are obscure and there is no effective and specific treatment for COVID-19-induced AKI. |
| 33444702 | The newly emerged severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) coronavirus initiated a pneumonia outbreak (COVID-19) that rapidly spread worldwide and quickly became a public health emergency of international concern; However to date, except Remdesivir, there are no clinically approved specific or effective medicines to prevent or treat COVID-19. |
| 33444770 | To date, there has not been a focused analysis of patients undergoing cardiothoracic surgery in the United States during the COVID-19 pandemic. |
| 33444904 | To date, over forty million people have officially been identified to be infected with this virus with less than 3% death rate. |
| 33447194 | Till date, India houses 10,453 confirmed COVID-19 patients with a death toll of 358 nationwide and the number is steadily rising with each passing day. |
| 33447332 | The coronavirus 19 (COVID-19) disease, which was declared in China in December 2019, very early on became a pandemic, claiming more than 28 million victims worldwide to date. |
| 33448868 | Research findings provide an up-to-date glimpse of the pandemic from the perspectives of current and future indirect environmental impacts and the post-pandemic situation. |
| 33449202 | However, a requirement of physical distancing to date compromises their achievement. […] The effectiveness of telerehabilitation can be potentiated by several technologies available to date: virtual reality can recreate realistic environments in which patients may bodily operate, wearable sensors allow to quantitatively monitor the patient’s performance, and signal processing may contribute to the prediction of long-term dynamics of patient recovery. |
| 33449247 | To date, a clear image is lacking of the critical issues Italian community pharmacists had to face and of how they responded in their daily work.. |
| 33449998 | This study represents the largest compilation to date of clinical and postmortem data from decedents with coronavirus disease 2019 (COVID-19). |
| 33450699 | Lockdown, isolation, quarantine and social distancing are proved to be only effective measures to prevent and tackle COVID-19 till date. |
| 33451327 | In the present single-centered, retrospective, observational study, we reported findings from 87 consecutive laboratory-confirmed COVID-19 patients with moderate-to-severe acute respiratory syndrome hospitalized in an intermediate Respiratory Intensive Care Unit (RICU), subdividing the patients in two groups according to the admission date (before and after March 29, 2020). |
| 33451350 | Relevant clinical trials for any prior indication were listed by identifier (NCT number) and checked for results and for timely result reporting (within 395 days of the primary completion date). |
| 33452826 | While there have been no supply issues to date, the framework developed early in the pandemic should facilitate timely responses to possible disruptions in future waves of infection. |
| 33453121 | However, the implications of telemedicine on patient-physician interaction, patient satisfaction, and absence of the personal touch have not been studied to date. […] The use of telemedicine regarding patients’ perspectives, emotions, and patient-physician communication in daily oncology practice has not been studied to date. |
| 33455926 | The expected date of final follow-up is May 2022. |
| 33458586 | While, at the initial outbreak, the treatment of patients had focused on the respiratory symptoms, many diverse clinical manifestations of the disease have to date been reported. |
| 33459550 | To date, the true incidence of stroke in patients with COVID-19 remains unclear. |
| 33460992 | To date, no antivirals directed against SARS-CoV-2 or effective vaccines to combat the viral infection are available. |
| 33461264 | The State of São Paulo (SSP) hosts the largest number of confirmed cases in Brazil, with over 60,000 cases to date. |
| 33461641 | Minimal research to date has explored their application or value in managing mental health during significant broad-scale public health crises. |
| 33462562 | To date, no specific therapies or vaccines have been approved for coronavirus. |
| 33462567 | However, there have been no reported cases with positive GM1 or GQ1b antibodies in the literature to date. |
| 33463658 | A literature search of MEDLINE, EMBASE, Scopus, Web of Science, CENTRAL, OpenGrey and preprint servers medRxiv and bioRxiv was performed, with no restriction on language or date of publication. |
| 33465283 | Several therapeutic strategies have been used until now but, to date, there is no specific therapy to treat SARS-CoV-2 infection. |
| 33465486 | The findings were consistent with the hypothesis of a propagating outbreak with decreasing incidence since the peak date of onset. |
| 33465833 | Notably, 59% (n = 411) felt they had received insufficient education regarding up-to-date guidance, with 81% (n = 565) advocating further training. |
| 33466134 | Coronavirus disease 2019 (COVID-19) is an emerging disease caused by severe acute respiratory syndrome coronavirus 2; no specific effective medication to treat the disease has been identified to date. |
| 33468418 | In addition, we cover the limitations of the research efforts to date and how the current knowledge translates into practice guidance. |
| 33468431 | The 30 day all-cause mortality from the date of presentation of injury was 20%. |
| 33468987 | This article reviewed the scientific evidence to date regarding the possible influence of environmental temperature and air pollution on the transmission of SARS-CoV-2. |
| 33469387 | Therefore, accurate and up-to-date information regarding prevention and control methods is essential. |
| 33470663 | To date, the vast majority of the studied antiviral and immunomodulatory agents have failed to improve outcomes of patients with COVID-19 except for dexamethasone. |
| 33471809 | To date, there is lack of studies describing clinical characteristics of the people at high risk of infection. |
| 33472675 | One hundred eighty eligible patients will be randomly assigned in a 1:1:1 ratio to receive either the inhibitor of C1e/kallikrein 20 U/kg intravenously on day 1 and day 4 plus standard care; or icatibant 30 mg subcutaneously, three doses/day for 4 days plus standard care; or standard care alone, as recommended in the clinical trials published to date, which includes supplemental oxygen, non-invasive and invasive ventilation, antibiotic agents, anti-inflammatory agents, prophylactic antithrombotic therapy, vasopressor support, and renal replacement therapy. |
| 33472681 | First posted date: April 14, 2020. |
| 33476312 | another 2.3% were not up to date for MMR and did not have a vaccine exemption. |
| 33478237 | To date, clinically effective agents for prevention and treatment of covid-19 infections are limited. |
| 33479261 | The study proves no correlation between the country surge date and the 2 weeks preceding temperature or humidity but shows an impressive linear correlation with latitude. […] The country surge date corresponds to the time when its sun UV daily dose drops below ≈ 34% of that of 0° latitude. […] The date of the surge is an intrapopulation observation and has the benefit of being triggered only by a parameter globally affecting the population, i.e. decreases in the sun UV daily dose. |
| 33480017 | The number of cases of SARS-Cov-2 contamination in Setif (Algeria) is constantly increasing, representing to date nearly 10% of all cases recorded throughout the country. |
| 33481754 | All these public mental health surveys were cross-sectional in design, and the journals efficiently made these articles available online in an average of 18.7 (range 1-64) days from the date they were received. |
| 33481773 | The most severe measures to date include all restaurants, pubs and cafes being ordered to close on 20th March, followed by a “stay at home” order on the 23rd March and the closure of all non-essential retail outlets for an indefinite period. […] We present a deterministic, age-structured transmission model that uses real-time data on confirmed cases requiring hospital care and mortality to provide up-to-date predictions on epidemic spread in ten regions of the UK. |
| 33482025 | To date, this is the largest study demonstrating a mortality benefit for the use of CCP in patients with COVID-19 compared to matched controls. |
| 33482149 | To date, the sequence data from tens of thousands of virus isolates have revealed hundreds of mutations. |
| 33483446 | Manual data were collected and recorded by the clinical research team for assessments which are not part of the structured electronic healthcare record, for example, symptom onset date. |
| 33485917 | We describe the largest COVID-19 VV-ECMO single-center experience to date and assess the utility of standard risk calculators. , 2020, at a single academic center was performed. |
| 33486202 | About seventy-nine million infections and more than 1.7 million death have been reported to date, along with destruction of the global economy. |
| 33486674 | Coronavirus Disease 2019 (COVID-19) is an acute respiratory syndrome, reported at the end of 2019 in China originally and immediately spread affecting over ten million world population to date. |
| 33487533 | Date of onset of initial symptoms or date of positive testing (for asymptomatic patients) were self-reported by the patients. |
| 33487885 | The new Coronavirus disease 2019 (COVID-19) is rapidly affecting the world population with statistics quickly falling out of date. |
| 33488023 | Despite an explosive growth in research, a comprehensive review of up-to-date information is lacking. |
| 33488032 | Compared to before January 21st, 2020 (the date of the first confirmed COVID-19 in Taiwan), the number of patients who have received echocardiography and cardiac catheterization has since fallen. |
| 33489530 | To date, the diagnostic criteria for COVID-19 include nasopharyngeal and oropharyngeal swabs. |
| 33489537 | Our study further illustrates the value of GT in localizing rapidly recovering interest in several of the most common elective orthopedic surgeries, enabling surgeons with up-to-date actionable data to guide the management of practices and healthcare facilities as the US slowly emerges from precautions endorsed during the COVID-19 pandemic. |
| 33489609 | Information obtained from the medical records included demographic data, date of visit, the reason for the visit, history of a similar episode, number of ED visits during the past year, priority given at the ED, length of hospitalization, diagnosis of COVID-19 at KAUH, known chronic diseases, and whether brain imaging was performed with which kind of imaging. |
| 33489854 | 72.2% responders were not up to date with their knowledge of tracheostomy safe practices. |
| 33490198 | Unfortunately, there is no adequate global and standard response to this pandemic to date, and each country is facing a crisis based on its situation, expertise, and hypotheses. |
| 33490999 | There have been few descriptions in the literature to date specifically examining initial coronavirus disease 2019 (COVID-19) patient presentation to the emergency department (ED) and the trajectory of patients who develop critical illness. |
| 33492377 | For the postexposure period (March 25-July 31), approximately 168 positive test results occurred for the studied organisms in the 2020 virus year, a positivity rate of 9.88 positive results per 100 tests that was much lower than the positivity rate of 29.90 positive results per 100 tests observed for this date range in the previous 5 virus years. |
| 33492400 | To date, there are few data on the physical therapist management of patients with COVID-19. |
| 33493012 | Time to death, censored at hospital discharge, or date of last follow-up. |
| 33495692 | To date, no drug has been clinically approved for treatment of COVID-19. |
| 33495739 | To date, there is no effective treatment for COVID-19-induced kidney dysfunction, and current treatments are yet limited to anti-inflammatory (e.g. ibuprofen) and anti-viral medications (e.g. |
| 33497425 | We obtained data from the Global Initiative on Sharing All Influenza Data repository by sampling all genomes available on that date. |
| 33498909 | Vaccination is one of the most effective approaches to protect against infectious diseases, and to date, multiple vaccines have been successfully used to protect against and eradicate both viral and bacterial pathogens. |
| 33499581 | To date, no evidence shows that respiratory viruses can be transmitted through a surgical plume or an aerosolized gas. |
| 33499887 | Date of trial registration: June 26, 2020. |
| 33500407 | While Digital contact tracing (DCT) has been argued to be a valuable complement to manual tracing in the containment of COVID-19, no empirical evidence of its effectiveness is available to date. |
| 33500591 | Unfortunately, to date no vaccine or antiviral therapeutic is approved thus there is an urgent need to discover antiviral agent to help the individual who are at high risk. |
| 33500595 | Past work has revealed that perceived stress relates to poorer outcomes, however, little work to date has examined factors that may exacerbate these outcomes, and no work to date has examined this relation in terms of COVID-19. |
| 33502141 | To date, there is lack of specific effective treatment or vaccine for the SARS-CoV-2, and clinical and laboratory research is still ongoing to find successful drugs. |
| 33502436 | To date, the association of psychiatric diagnoses with mortality in patients infected with coronavirus disease 2019 (COVID-19) has not been evaluated. […] The final date of follow-up was July 15, 2020. […] Patients were categorized based on the following International Statistical Classification of Diseases, Tenth Revision, Clinical Modification diagnoses before their testing date: (1) schizophrenia spectrum disorders, (2) mood disorders, and (3) anxiety disorders. |
| 33504339 | In Taiwan, most cases to date were imported or linked to imported cases. |
| 33504412 | Searches were designed to identify: (1) systematic reviews (<10 years), or (2) primary intervention studies (no date limit) reporting evidence on anti-stigma interventions (in relation to COVID-19 or other infectious/stigmatised conditions) or (3) additional relevant materials. |
| 33507887 | The growth rate during this interval was the highest to date in Wisconsin and among the highest in the United States during that time (1). |
| 33508281 | To date, the association of ACEi and/or ARBs with the up-regulation of ACE2 expression has not been defined distinctively. |
| 33509605 | Evidence on the population-level mental health impacts of COVID-19 are beginning to amass; however, to date, there are significant gaps in our understandings of whose mental health is most impacted, how the pandemic is contributing to widening mental health inequities, and the coping strategies being used to sustain mental health. |
| 33509611 | There have been no reports of infection of dental staff or patients during dental treatment in China to date. |
| 33509629 | However, to date, limited definitive evidence exists regarding many of these aspects, creating a challenging landscape for both patients and physicians to obtain and provide the best clinical care. |
| 33509967 | Outcomes were days from the first COVID-19 case in the origin of Hubei Province to the date when case was first detected in a destination province, and cumulative number of confirmed cases. |
| 33510400 | This article examines how Argentina, Brazil, Chile, Colombia, Mexico, and Peru addressed the COVID-19 pandemic and the effectiveness of these policy responses from the date each country declared a sanitary emergency, between middle and late March 2020 to the most recent available measurement on 23 September 2020. |
| 33511495 | Limitations in epidemiologic data available to date do not allow for assessing the risk and severity of COVID-19 in patients with SLE. |
| 33512353 | Peter Piot, head of the London School of Hygiene & Tropical Medicine noted that none of the CoViD-19 vaccines have offered much data to date. |
| 33512355 | In addition to doctors and nurses, hospital and clinical pharmacists also struggle to keep up to date. |
| 33513240 | Till date, there is paucity of published literature on clinical manifestations of Coronavirus disease 2019 (COVID-19) in children from low-middle-income countries (LMIC). |
| 33513562 | As COVID-19 continues to alter healthcare delivery, user activity metrics suggest that our solution will remain important in our efforts to continue providing safe and up-to-date clinical care. |
| 33513563 | To date, chilblain-like lesions’ association with COVID-19 remains controversial in the scientific community. |
| 33515712 | We developed the predictive model for severe patients of COVID-19 based on the clinical date from the Tumor Center of Union Hospital affiliated with Tongji Medical College, China. |
| 33518410 | While SARS-CoV-2 assays can suffer from poor sensitivity, all FDA authorized assays to date are intended to be qualitative. |
| 33518823 | Our method traces the initial outbreak date in Santa Clara County back to January 20, 2020 (95% CI: December 29, 2019-February 13, 2020). |
| 33519121 | Up to date, the spread of the outbreak continues to complicate our lives, and therefore, several research efforts from many scientific areas are proposed. |
| 33519127 | To date, however, there is no study that fills this gap in a comprehensive way. |
| 33519145 | Up to date, there has been no specific cure to treat the disease. |
| 33519188 | We have reviewed the current information on SARS-CoV-2 in the ophthalmologic field and provide up-to-date recommendations to help create protocols that can adapt to the dynamic situation of ophthalmologic institutions, patient cases, economic situations and access to diagnostic tests. |
| 33519271 | To date, 06 human coronaviruses (HCoVs) are reported; α-CoVs (HCoVs-NL63 and HCoVs-229E) and β-CoVs (HCoVs-OC43, HCoVs-HKU1, SARS-CoV, MERS-CoV). |
| 33519324 | On-going assessment of the epidemiological features and future impacts of the COVID-19 disease is required to stay up-to-date of any changes to its spread dynamics and foresee needed resources and consequences in different aspects as social or economic ones. |
| 33519345 | The following data were collected: date of admission, gender, age and details of intensive care unit admission and outcomes. |
| 33519949 | However, to date, and despite such promise, we have received very limited information about the potential of nanomedicine to fight against COVID-19 or as an adjunct therapy in the treatment regimen. |
| 33520006 | We calculated the correlations between the polarities of financial market indicators and posts on Twitter by applying a date shift on tweets. |
| 33520252 | A cross-sectional study based on retrospective interviews was conducted on 1021 individuals with RT-PCR-confirmed COVID-19 admitted in six different hospitals in Bangladesh and who recovered 4 weeks before the interview date. |
| 33520580 | As information from COVID-19 is evolving rapidly, this review will help the researcher to consider new insights and potential therapeutic approaches based on up-to-date knowledge. |
| 33520663 | To date, however, none has looked at the impact of culture on market responses to disasters. |
| 33520683 | This present review aims to comprehensively summarize the up-to-date scientific literatures on biological activities of plant- and mushroom-derived compounds relevant to mechanistic targets involved in SARS-CoV-2 infection and inflammatory-associated pathogenesis, including viral entry, replication and release, and the renin-angiotensin-aldosterone system (RAAS). studies were excluded. molecular docking analysis, herein, we provide a total of 150 natural compounds as potential candidates for development of new anti-COVID-19 drugs with higher efficacy and lower toxicity than the existing therapeutic agents. |
| 33521067 | By incorporating the most up-to-date knowledge, we have developed a detailed, easy-to-follow novel protocol for producing SARS-CoV-2 spike-bearing pseudovirus using the VSV-ΔG system. |
| 33521322 | To date, there is no approved vaccine or specific drug to prevent or treat COVID-19, while the infection is globally spreading at an alarming rate. |
| 33521378 | The COVID-19 death toll has involved to date more than 1 million confirmed deaths. |
| 33521495 | To date, the practice of global emergency medicine (GEM) has involved being “on the ground” supporting in-country training of local learners, conducting research, and providing clinical care. |
| 33521582 | Using registries, custom dashboards and operational reports were developed to provide daily high-level summary for clinical practice use and provide up to date information used to manage individual patients impacted by COVID-19, including support of case identification, contact isolation and other care management tasks. we developed and implemented a systematic approach for using EHR patient registries to manage the COVID-19 pandemic that proved feasible and useful for managing a large multistate group clinical practice. |
| 33521583 | The data included basic deidentified demographics, symptoms at intake into the program, date of symptom onset, risk factors, location, and outcomes including hospitalization, ICU admission, and death. |
| 33522697 | Participants’ demographic and clinical information, such as age, the American Society of Anesthesiologists score, surgical date and location, surgical subspecialty and procedure name, was included. |
| 33522928 | Highest estimates of cumulative deaths (and cases) for latest date available in 2020 were 418,834 on 2020-12-19 (and 41,475,792 on 2020-12-31). |
| 33522951 | Protocol version/date May 21, 2020. […] Due to recruitment adaptations to Primary Care changes, the authors anticipate the trial will finish recruiting on April 10, 2021. , 2020, and the trial start date was June 15, 2020. |
| 33522974 | Countries from regions with less pronounced influenza activity including South Asia and Sub-Saharan Africa, showed more heterogeneity in COVID-19 epidemics seen to date. […] Ecological consistency in COVID-19 trends seen to date with influenza trends suggest the potential for shared individual, structural, and environmental determinants of transmission. |
| 33524563 | Till date millions of people are infected by SARS-CoV-2 throughout the world, while no potential therapeutics or vaccines are available to combat this deadly virus. |
| 33524979 | To date, viral vector-based vaccines, genetic vaccines, attenuated vaccines, and protein-based vaccines are the major vaccine types tested in the clinical trials. |
| 33525225 | The P.A.R.M.A. protocol is the result of a periodic review literature update, which has allowed us to take charge of patients affected by COVID-19 according to the most up-to-date clinical evidences, guaranteeing a shared and uniform treatment within a local reality in an era of health emergency. |
| 33525447 | This article provides an up-to-date summary of recent epidemiological and intervention studies on a possible role of vitamin D supplementation for preventing severe COVID-19 cases and deaths. |
| 33525556 | With this review, we provide an up-to-date overview of the available evidence on non-invasive remote monitoring in chronic HF patients and provide future perspectives that may significantly benefit the broader group of HF patients. |
| 33525993 | Even though several structures were reported to date, its dynamics is not understood well. |
| 33526252 | LitCOVID is a data set containing the most up-to-date literature around COVID-19. |
| 33526409 | This framework was implemented in a large health care system, and to date compliance has been monitored at 15 facilities. |
| 33526961 | The Coronavirus disease (Covid-19) has been declared a pandemic by World Health Organisation (WHO) and till date caused 585,727 numbers of deaths all over the world. |
| 33527510 | Given the rapid widespread transmission of the COVID-19 disease worldwide, a more comprehensive and up-to-date understanding of its features is needed to better inform nurses, clinicians and public health policy makers. […] This review provides an up-to-date synthesis of main diagnostic features of SARS-CoV-2-positive patients at the time of hospitalisation. |
| 33528655 | With the availability of the vaccination many questions have arisen for patients as well as for physicians, which are addressed as up to date as possible in this hot topic article. |
| 33528824 | To date, there has not been discussion of persistent neurocognitive deficits in patients with milder COVID-19. |
| 33530357 | To date, thousands of cases of COVID-19 have been reported in the United Kingdom, and over 45,000 patients have died. |
| 33530777 | The observations available to date suggest that COVID-19 vaccine can be administered safely to hypertensive patients. |
| 33530781 | The observations available to date suggest that COVID-19 vaccine can be administered safely to hypertensive patients. |
| 33531356 | To date, there has been no systematic review on telerehabilitation for respiratory tract diseases, including COVID-19. |
| 33531805 | Furthermore, it elucidates the achievements in developing COVID-19 vaccines and therapeutics to date through existing approaches. |
| 33532003 | To date, only dexamethasone has shown to be an effective treatment in the subgroup of patients requiring oxygen supplementation; however, countless trials including novel therapeutic approaches are ongoing. |
| 33532098 | To date, there has only been one reported case of patient salvage with arterial or partial arterial support. |
| 33532594 | IDentif.AI independently mirrored clinical trial outcomes to date without any data from these trials. |
| 33532755 | EMS call volumes were compared before and after March 10, the date of a statewide emergency declaration. |
| 33533178 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic and has taken lives of approximately two million people to date. |
| 33536046 | Since this date, there have been variable jurisdictional responses, including lockdowns, and restrictions on podiatry practice. […] Podiatrists also described their “marathon” journey through the pandemic to date, with quotes describing their challenges and highlights. |
| 33536937 | The mechanisms are still poorly qualified to date. |
| 33537824 | To date, limited effective therapies are available for the prevention or treatment of COVID‑19; therefore, it is necessary to propose novel treatment options with immunomodulatory effects. |
| 33538477 | To date, however, only one school has had its curriculum approved for this purpose. |
| 33539060 | All patients were successfully rescheduled and underwent their elective arthroplasty procedure within 6 weeks of their original surgery date. |
| 33539307 | To date, however, little information has been provided regarding telehealth uptake among this high-risk population. |
| 33540179 | Evidence to date shows the benefit of statin use in patients with COVID-19. |
| 33542386 | We use SafeGraph smart device location data and variation in the date that US states and counties issued face mask mandates as a set of natural experiments to investigate risk compensation behavior. |
| 33543649 | At our institution, we are adding questions regarding the date(s) and laterality of administration of COVID-19 vaccination to our intake form before all breast imaging examinations. |
| 33544692 | RRTF initially convened in March 2020 to prioritize and streamline COVID-19 observational research, and to date has reviewed over 60 protocols and made recommendations to the institutional review board (IRB). |
| 33546734 | Additionally, the date of restarting the withdrawn medication or whether the medication was re-prescribed on discharge or not, will be collected. |
| 33547062 | No other immunomodulator demonstrated efficacy on mortality to date, with however inconsistent results for tocilizumab. |
| 33547637 | The ability to access and process up-to-date, evidence-based information was perceived as important. |
| 33549417 | Consecutive primary hip, knee, and partial knee arthroplasties, performed 30 days before March 15, 2020 (date of practice closure), were included from a single institution, yielding 47 cases. |
| 33549421 | The SARS-CoV-2 (COVID-19) pandemic caused a massive disruption in elective arthroplasty practice in the United States that to date has not been quantified. |
| 33549565 | Records were abstracted for comorbidities, signs and symptoms, and illness outcomes during the 2 weeks before and after the date of positive specimen collection. |
| 33550152 | However, no individual-level study has confirmed the association to date. exposure and hospitalizations for COVID-19, adjusting for socioeconomic characteristics and comorbidities. |
| 33551522 | However, to date, there is a dearth of research into factors that could lead to UK residents’ acceptance or rejection of COVID-19 vaccines. |
| 33551661 | To date, there are no specific drugs formulated for it, and researchers around the globe are racing against the clock to investigate potential drug candidates. |
| 33551672 | Though efforts on development of SARS-CoV-2 vaccine have been started earlier as soon as the pandemic was emerged, till date no effective drug or vaccine has been validated with significant efficacy against the disease; therefore, there is a dire need to design effective vaccine against SARS-CoV-2. |
| 33552379 | This behavior does not differ from that of respiratory viruses known to date: in naturally occurring viral respiratory infections, reinfections are exceptional. […] From the information we have to-date, we suggest that, in principle, patients who have already overcome the infection should not be prioritized to the SARS CoV-2 vaccine. |
| 33554040 | Most studies to date have focused on hospitalized patients with severe COVID-19, thereby limiting the generalizability and interpretability of the association between cancer and COVID-19 severity. |
| 33554523 | The evidence accumulated to-date has hence persuaded us to develop a tentative algorithm, which would magnify the potential benefits of rapid antigen testing in SARS-CoV-2 diagnostics. |
| 33554582 | To find out if the expressed breast milk delivery rate to neonatal intensive care unit (NICU) for babies who were hospitalized for any reason other than COVID-19, and exclusive breastfeeding (EB) rates between discharge date and 30th day of life of those babies were affected by COVID-19 pandemic. […] Babies who were hospitalized before the date first coronavirus case was detected in our country were included as control group (CG). […] The study group was divided into two groups; study group 1 (SG1): the mothers whose babies were hospitalized in the period when mother were asked not to bring breast milk to NICU, study group 2 (SG2): the mothers whose babies were hospitalized after the date we started to use the informed consent form for feeding options. |
| 33555336 | Mixed-effects logistic regression was used to examine the association between date and self-reported mental distress (measured with the four-item Patient Health Questionnaire) among U.S. adults overall and among sociodemographic subgroups defined by sex, age, race/ethnicity, household structure, federal poverty line, and census region. |
| 33555378 | To date there have been no specific treatment options available for this life-threatening disease. |
| 33556319 | To date, only monoclonal antibodies have been shown to be effective for outpatients with COVID-19. |
| 33556957 | Multiple drugs have been tried to date in the treatment of COVID-19. |
| 33557873 | To date no universally agreed approach is available for this disease. |
| 33558479 | High susceptibility has limited the role of climate in the SARS-CoV-2 pandemic to date. |
| 33558864 | No epidemiological investigations to date have described evidence suggesting that COVID-19 is an STD. |
| 33559756 | Closer to the rank list due date, training information, the graduate medical education (GME) documents, and the diversity and wellness initiatives seemed to have more activity. |
| 33559821 | Study baseline was defined as the date of first prescription of chlorpromazine during hospitalization for COVID-19. |
| 33560530 | The search covered the period from the inception date of each database to September 13, 2020. |
| 33561374 | To date, the only effective means to respond to the spreading of the COVID-19 pandemic are non-pharmaceutical interventions (NPIs), which entail policies to reduce social activity and mobility restrictions. |
| 33562501 | To this end, a source code written in R language is attached that allows for the customization of the analysis and provides up-to-date results. |
| 33563148 | To date, about half of antivirals have been created based on nucleosides. […] To date, two known nucleoside drugs (Ribavirin, Favipiravir) have been recommended for the treatment of SARS-CoV-2 infection and nine hit compounds based on nucleosides and their analogues have been found, one of which efficiently suppressing SARS-CoV-2 replication and eight others inhibiting SARS-CoV replication. |
| 33563156 | To date, there is no selective antiviral agent for the management of pathologies associated with covid-19 and the need for an effective agent against it is essential. |
| 33564461 | All were asymptomatic, received home-based care via telecommunication and were operated at a later date when test turned out negative. |
| 33564538 | Background To date, several pharmacological agents have been employed in the treatment and management of the coronavirus disease 2019 (COVID-19). |
| 33565568 | To date, it is unknown how many Italians have had or have a mild SARS-CoV-2 infection, because of the lack of epidemiological studies involving the general population. |
| 33565741 | To date, COVID-19 has been mainly investigated concerning the acute and subacute phase implications and management. |
| 33566109 | In the main analyses, patients currently receiving α1-blockers were compared with those not receiving α1-blockers (defined as patients with no prescription for an α1-blocker filled within 365 days before the index date) and those currently receiving 5α-reductase inhibitors. |
| 33566898 | To date, there are no scientific evidence to uphold the use of chlorine dioxide or derivatives as preventive or therapeutic agents against COVID-19. |
| 33568226 | It was started on July 30, 2020, and the estimated end date for the trial is August 15, 2021. |
| 33568967 | To date, the cases due to this disease are increasing exponentially, but there is no vaccine of COVID-19 available commercially. |
| 33569200 | Five databases were searched on April 15, 2020, without publication date restriction. |
| 33569392 | Owing to the high mortality and the spread rate, the infectious disease caused by SARS-CoV-2 has become a major threat to public health and social economy, leading to over 70 million infections and 1. 6 million deaths to date. |
| 33569525 | Up to date, prophylactic anticoagulants are recommended in all patients that are hospitalized with COVID-19 infections to prevent venous and arterial thrombotic complications. |
| 33571141 | 1.9 million deaths globally, as of date. |
| 33571429 | Memory B cells play a fundamental role in host defenses against viruses, but to date, their role has been relatively unsettled in the context of SARS-CoV-2. |
| 33571916 | To date, no study has evaluated the association of alcohol dependence with the outcome of the COVID-19 infection. |
| 33572857 | To this end, current up-to-date information on the coronavirus evolution and SARS-CoV-2 modes of transmission, detection techniques and current control and prevention strategies are summarized in this review. |
| 33572863 | To date, past research studying the connections between dietary behaviors, alcohol misuse, sleep, and resilience commonly investigated singular relationships between two of the constructs. |
| 33573545 | However, none has succeeded till date to provide a substantial cure to it and evidently patient recovered from covid-19 further suffered again. |
| 33573673 | However, to date, no studies have examined the prevalence of PGD among people bereaved due to COVID-19. |
| 33573696 | Protocol Number : SCRUND GIMS Noida Study 1,Version: 2.0 Protocol Date : 20.08.2020 The recruitment period is completed for the trial. |
| 33574010 | Median day of plasma infusion from date of diagnosis of Covid-19 infection was 4 days (range: 2-25 days). |
| 33575412 | Through association of observed case trends with a series of (county-specific) data-driven dynamic interdependencies (lagged values), a systematically non-assumptive approximation of VAR representation for COVID-19 patterns to-date and prospective upcoming trends was produced. range: 0.9221-0.9751, all p < 0.001). |
| 33575849 | Only a few reports of AHLE in coronavirus disease 2019 (COVID-19) patients have been described to date. |
| 33576464 | To date, host innate immunity may be the only identified direct factor associated with viral replication. |
| 33577581 | However, there is to date little research chronicling how people perceived their changed everyday lives and which consequences this had. |
| 33577704 | Subsequent changes in DNH orders, hospitalizations, and deaths were ascertained by retrospective chart review from the date of new DNH through 8/5/2020. |
| 33579540 | The primary outcome was 30-day COVID-19 infection among patients, with day 0 the date of surgery. |
| 33580823 | Allergic reactions and anaphylaxis account for a substantial proportion of the adverse reactions to these vaccines observed to date, but overall they are rare. |
| 33581991 | To date, only 1 case of combined superior mesenteric artery and superior mesenteric vein thrombosis caused by COVID-19 has been reported. |
| 33582654 | To date, at least 27 autopsy studies on the brains of COVID-19 patients can be retrieved through PubMed/MEDLINE, among which neuropathological alterations were observed in the brainstem in 78 of 134 examined patients, and SARS-CoV-2 nucleic acid and viral proteins were detected in the brainstem in 16/49 (32.7%) and 18/71 (25.3%) cases, respectively. |
| 33585153 | The results achieved to date on the subject are promising. |
| 33585175 | In this paper, we have elaborated on the therapeutic strategies that have been hypothesized or trialed to-date, the mechanism of action of each therapeutic, the clinical trials finished or in-process that support the use of each therapeutic, and the adverse effects associated with each therapeutic. |
| 33587028 | This work attempts to bridge the critical gap regarding the genomic landscape and associate mutations in SARS-CoV-2 from a highly infected southern region of India, which was lacking to date. |
| 33587745 | Up-to-date genomic data of severe acute respiratory syndrome coronavirus 2 and Middle-East respiratory syndromes-CoV strains demonstrate that the stress from host miRNA milieus sustained even after their epidemics in humans. |
| 33588588 | To date, no published research has been found on stroke caregiving during the COVID-19 pandemic. |
| 33589305 | Studies to date are largely surveys and lack meaningful involvement from service users in their design, planning, and delivery. |
| 33589506 | To this date, there has been no identified COVID-19 disease in any protected code blue (PCB) team members. |
| 33592050 | Profession, gender, age and date of diagnosis were matched for 186 case-control pairs. |
| 33593248 | Although preventing these infections by using vaccines has been the most successful strategy to date, effective vaccines are not always available. |
| 33593784 | To date, a search of ClinicalTrials.gov identified 21 potentially eligible trials for this meta-analysis. |
| 33594938 | ), the disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), represents an ongoing global health challenge and the deadliest epidemic coronavirus outbreak to date. |
| 33595634 | The primary outcome was length of stay, defined as the time from the date of randomization to hospital discharge. |