DANOPREVIR


DrugBank ID: db11779
DrugCentral: danoprevir
Synonymous : None



Drug Sentece Context


Table 1. Analysis of context sentence of danoprevir gene in 6 abstracts.

pmid sentence
32501538 Patients were divided into two groups according to different treatment plans (danoprevir and lopinavir/ritonavir). […] COVID-19 patients treated with danoprevir or lopinavir/ritonavir were all improved and discharged. […] Additionally, under the circumstance that there was no significant difference in patients’ general information between the two groups, we found that the mean time to achieve both negative nucleic acid testing and hospital stays of patients treated with danoprevir were significantly shorter than those of patients with lopinavir/ritonavir. […] Collectively, applying danoprevir is a good treatment plan for COVID-19 patients.
32643436 Initial findings from antivirals such as remdesivir, favipiravir, danoprevir or lopinavir with ritonavir are presented.
32696811 After treatment with ritonavir-boosted danoprevir (DNVr, 100/100 mg, once daily), all four patients showed two to three consecutive negative SARS-CoV-2 RNA and were thus discharged from hospital.
32798373 Among the drugs that are being tested in clinical trials for COVID-19, Danoprevir and Darunavir have the highest binding affinity for the target main protease of SARS-CoV-2.