DALTEPARIN


DrugBank ID: db06779
DrugCentral: dalteparin
Synonymous :alpha-heparin



Drug Sentece Context


Table 1. Analysis of context sentence of dalteparin gene in 4 abstracts.

pmid sentence
32335456 We suppose that host cell proteases including furin (as expressed highly in lungs), factor Xa and cathepsin are possible targets to decrease viral burden, therefore unfractioned heparin and low molecular weight heparin-LMWH (specifically dalteparin and tinzaparin for their anti inflammatory action) can be potential inhibitors of multiple endoproteases involved in virus infectivity.
32776010 A computed tomography (CT) pulmonary angiogram demonstrated large bilateral pulmonary emboli with right heart strain, for which he received intravenous systemic thrombolysis followed by therapeutic weight-adjusted anticoagulation with low molecular weight heparin (dalteparin). […] The dose of therapeutic dalteparin was increased incrementally to an eventual dose of 12,500 units twice daily.
32920503 Standard thromboprophylaxis was given with dalteparin (75-100 IU/kg subcutaneously). […] There was no significant correlation between dalteparin dose and anti-factor Xa activity.
33128800 High-dose dalteparin was adjusted by D-dimer. […] D-dimer peaked at 3.8 mg/L (2.1-5.3), and maximum dalteparin dose was 15 000 IU/24 h (10 000-15 000).
33225952 Patients were categorized into three groups according to initial daily dose of thromboprophylaxis: low (2500-4500 IU tinzaparin or 2500-5000 IU dalteparin), medium (> 4500 IU but < 175 IU/kilogram, kg, of body weight tinzaparin or > 5000 IU but < 200 IU/kg of body weight dalteparin), and high dose (≥ 175 IU/kg of body weight tinzaparin or ≥ 200 IU/kg of body weight dalteparin).