CYTIDINE

Drug Sentece Context

Table 1. Analysis of context sentence of cytidine gene in 3 abstracts.

pmid	sentence
32432977	The antiviral effect of gemcitabine was suppressed efficiently by the cytidine nucleosides.
32797103	These enzymes are cytidine deaminases which transform cytosine into uracil. […] They preferentially mutate cytidine preceded by thymidine making the 5’TC motif their favored target.
32933166	Anti-Neu5Gc appeared in hominins following the inactivation of the cytidine-monophosphate-N-acetyl-neuraminic acid hydroxylase gene, which led to the loss of Neu5Gc <6 million-years-ago.
33006981	Similarly, to what was previously reported for rubella virus, C to U changes showed enrichment in the uCn motif, which suggested a subclass of APOBEC cytidine deaminase being a source of these substitutions.
33108121	Here we show that the metabolism of all cells is coordinated by the availability of a core building block of the cell’s genome, cytidine triphosphate (CTP).
33125064	Cytidine triphosphate (CTP) is at the crossroad of the processes allowing SARS-CoV-2 to multiply, because CTP is in demand for four essential metabolic steps.
33161087	Of the total 20,163 instances of polymorphism detected across global genomes, 12,594 and 7569 involved transitions and transversions, predominated by cytidine-to-uridine and guanosine-to-uridine conversions, respectively.
33472904	Interestingly, both mutations are of C>T type, a common single nucleotide polymorphism (SNP) that may be associated with strong host cell mRNA editing mechanisms known as APOBEC cytidine deaminase (3, 4).
33545556	Members of the APOBEC family of cytidine deaminases show antiviral activities in mammalian cells through lethal editing in the genomes of small DNA viruses, herpesviruses and retroviruses, and potentially those of RNA viruses such as coronaviruses.
33576494	Here, we immunized cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMAH) and α1,3-galactosyl-transferase (GGTA1) double knockout (DKO) pigs with the SARS-CoV-2 spike receptor-binding domain (RBD) to produce glyco-humanized polyclonal neutralizing antibodies (GH-pAb) lacking Neu5Gc and α-Gal epitopes.