CYCLOPHOSPHAMIDE


DrugBank ID: db00531
DrugCentral: cyclophosphamide
Synonymous :(+-)-cyclophosphamide | (rs)-cyclophosphamide | 2-[bis(2-chloroethylamino)]-tetrahydro-2h-1,3,2-oxazaphosphorine-2-oxide | anhydrous cyclophosphamide | bis(2-chloroethyl)phosphoramide cyclic propanolamide ester | ciclofosfamida | ciclofosfamide | cyclophosphamid | cyclophosphamide | cyclophosphamide anhydrous | cyclophosphamidum | cytophosphane | n,n-bis(2-chloroethyl)tetrahydro-2h-1,3,2-oxazaphosphorin-2-amine 2-oxide



Drug Sentece Context


Table 1. Analysis of context sentence of cyclophosphamide gene in 9 abstracts.

pmid sentence
32283185 Post-transplant cyclophosphamide (ptCY), is an increasingly used approach for graft-versus-host disease (GVHD) prophylaxis but the impact of graft cryopreservation on the outcomes of allo-HCT using ptCY is not known.
32305989 For standard-risk patients, we recommend the following: ixazomib, lenalidomide, and dexamethasone (IRd) (preferred), cyclophosphamide lenalidomide and dexamethasone (CRd), daratumumab lenalidomide and dexamethasone (DRd), lenalidomide, bortezomib, and dexamethasone (RVd), or cyclophosphamide, bortezomib, and dexamethasone (CyBorD).
32361703 Methylprednisolone and cyclophosphamide were prescribed due to suspected glomerulonephritis.
32513299 Have used other anti-pulmonary fibrosis drugs in the past 14 days, such as nintedanib, pirfenidone, penicillamine, colchicine, tumor necrosis factor alpha blocker, imatinib, glucocorticoid hormones, morphomycodyl esters, azathioprine, cyclophosphamide, interferon-γ, and traditional Chinese medicine;6.
32526511 We propose the use of cyclophosphamide as an immunomodulator, given its proven role in various settings including autoimmune diseases, and in the post-haploidentical stem cell transplant. […] Cyclophosphamide could deplete cytotoxic and effector T cell populations while relatively sparing the regulatory T cells (Tregs). […] Cyclophosphamide could tip the balance away from the overtly pro-inflammatory and could be a less expensive and effective alternative to the currently investigated monoclonal antibodies.
32733908 Pulses of methylprednisolone along with cyclophosphamide were applied.
32809050 In the case of outpatients under immunosuppression with proven COVID-19 more than 50% of the respondents would refrain from administering intravenous high-dose steroids, cyclophosphamide, anti-CD20 antibodies as well as BAFF, CTLA‑4 and TNF-alpha blockades.
32879154 A 69-year-old woman with lymphoma-type ATL was treated using cyclophosphamide, doxorubicin, vincristine, prednisolone and mogamulizumab (M-CHOP) with substantial efficacy.
32892275 Ixazomib-based regimens included ixazomib-lenalidomide-dexamethasone (IRd) in 44.7% of patients, ixazomib-dexamethasone (Id) in 29.4%, and Id plus another agent (doxorubicin, cyclophosphamide, thalidomide, or daratumumab) in 25.9%.
32900822 Cyclophosphamide (CyP) immunosuppressed or RAG2 knockout (KO) hamsters were exposed to SARS-CoV-2 by the respiratory route. […] We demonstrate the efficacy of a novel neutralizing monoclonal antibody using the cyclophosphamide transient suppression model.
32931985 Available data suggest no increased frequency or risk of respiratory viral events with NSAIDs, hydroxychloroquine, sulfasalazine, methotrexate, azathioprine, mycophenolate mofetil, cyclophosphamide, or apremilast.
32983161 With only few case studies published on SARS-CoV-2 infection in patients with rheumatic diseases, we report a 25-year-old male who developed moderate coronavirus disease 2019 (COVID-19) with fever, mild dyspnea, and no major complications despite having received high-dose prednisolone, cyclophosphamide, and rituximab for the treatment of highly active, life-threatening eosinophilic granulomatosis with polyangiitis (EGPA).
33019894 Due to RP-ILD worsening, immunosuppressive therapy was intensified using methylprednisolone pulses, cyclophosphamide, tofacitinib and intravenous immunoglobulin without response.