CONIVAPTAN
DrugBank ID: db00872
DrugCentral: conivaptan
Synonymous :4’-((4,5-dihydro-2-methylimidazo(4,5-d)(1)benzazepin-6(1h)-yl)carbonyl)-2-biphenylcarboxanilide | conivaptan
Drug Sentece Context
Table 1. Analysis of context sentence of conivaptan gene in 4 abstracts.
| pmid | sentence |
|---|---|
| 32308266 | We further report that Conivaptan and Azelastine are mainly involved in hydrophobic interactions with active site residues. |
| 32426387 | Among them, 8 drugs (bedaquiline, brequinar, celecoxib, clofazimine, conivaptan, gemcitabine, tolcapone, and vismodegib) showed in vitro activities against the proliferation of a feline infectious peritonitis (FIP) virus in Fcwf-4 cells. |
| 32563698 | They are all old drugs as follows, anisomycin, antimycin A, atovaquone, chloroquine, conivaptan, emetine, gemcitabine, homoharringtonine, niclosamide, nitazoxanide, oligomycin, salinomycin, tilorone, valinomycin, and vismodegib. |
| 32752938 | Similar analysis with RdRp showed that eltrombopag, tipranavir, ergotamine, and conivaptan bound to the enzyme with high binding free energies. […] Docking results suggest that ergotamine, dihydroergotamine, bromocriptine, dutasteride, conivaptan, paliperidone, and tipranavir can bind to both enzymes with high affinity. |
| 32838660 | Conivaptan, an arginine vasopressin antagonist drug exhibited the highest binding energy (-8.4 Kcal/mol) and maximum stability with the amino acid residues present at the active site of the Nsp9 replicase. […] Our findings suggest Conivaptan and Tegobuvir as potential therapeutic agents against SARS-CoV-2. |