CIDOFOVIR


DrugBank ID: db00369
DrugCentral: cidofovir
Synonymous :({[(s)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid | (s)-(3-(4-amino-2-oxopyrimidin-1(2h)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acid | (s)-1-(3-hydroxy-2-phosphonomethoxypropyl)cytosine | (s)-1-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine | (s)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine | (s)-hpmpc | [(s)-2-(4-amino-2-oxo-2h-pyrimidin-1-yl)-1-hydroxymethyl-ethoxymethyl]-phosphonic acid | [[(s)-2-(4-amino-2-oxo-1(2h)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]phosphonic acid | 1-(s)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine | 1-[(s)-3-hydroxy-2-(phosphonomethoxy)propyl]cytosine | cdv | cidofovir | cidofovir anhydrous | cidofovirum



Drug Sentece Context


Table 1. Analysis of context sentence of cidofovir gene in 1 abstracts.

pmid sentence
32562705 While all 11 molecules tested displayed incorporation, 6 exhibited immediate termination of the polymerase reaction (triphosphates of Carbovir, Ganciclovir, Stavudine and Entecavir; 3’-OMe-UTP and Biotin-16-dUTP), 2 showed delayed termination (Cidofovir diphosphate and 2’-OMe-UTP), and 3 did not terminate the polymerase reaction (2’-F-dUTP, 2’-NH2-dUTP and Desthiobiotin-16-UTP). […] Prodrugs of five of these nucleotide analogues (Cidofovir, Abacavir, Valganciclovir/Ganciclovir, Stavudine and Entecavir) are FDA-approved medications for treatment of other viral infections, and their safety profiles are well established.
32834922 Compared to the other nine medicines, brincidofovir, an ether lipid ester analog of cidofovir with potent antiviral activity, showed the highest docking scores and binding interactions.