CEFUROXIME
DrugBank ID: db01112
DrugCentral: cefuroxime
Synonymous :(6r,7r)-3-[(carbamoyloxy)methyl]-7-{[(2z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | cefuroxim | cefuroxima | cefuroxime | cefuroximo | cefuroximum | cephuroxime
Drug Sentece Context
Table 1. Analysis of context sentence of cefuroxime gene in 4 abstracts.
| pmid | sentence |
|---|---|
| 32338164 | The results show the effectiveness of Sofosbuvir, Ribavirin, Galidesivir, Remdesivir, Favipiravir, Cefuroxime, Tenofovir, and Hydroxychloroquine, in binding to SARS-CoV-2 RdRp. |
| 32364041 | The covalent docking showed that saquinavir, ritonavir, remdesivir, delavirdine, cefuroxime axetil, oseltamivir and prevacid have the highest binding energies MMGBSA of -72.17, -72.02, -65.19, -57.65, -54.25, -51.8, and -51.14 kcal/mol, respectively. |
| 32538276 | One drug with several anecdotal accounts of benefit is Cefuroxime. […] The aim of this study was to identify and summarize in silico evidence for possible activity of Cefuroxime against SARS-CoV-2. […] We searched Medline, Embase, Scopus, Web of Knowledge, and Google Scholar for original studies published between 1st Feb, 2020 and 15th May, 2020 that screened drug libraries, and identified Cefuroxime as a top-ranked potential inhibitor drug against SARS-CoV-2 proteins. […] These studies reported Cefuroxime as a potential inhibitor of 3 key SARS-CoV-2 proteins; main protease, RNA dependent RNA polymerase, and ACE2-Spike complex. […] Our scoping review identified significant in silico evidence that Cefuroxime may be a potential multi-target inhibitor of SARS-CoV-2. […] Further in vitro and in vivo studies are required to evaluate the potential of Cefuroxime for COVID-19. |
| 33505872 | The nucleotide inhibitors such as sofosbuvir, ribavirin, galidesivir, remdesivir, favipiravir, cefuroxime, tenofovir, and hydroxychloroquine (HCHL), setrobuvir, YAK, and IDX-184 were found to be effective in binding to SARS-CoV-2 RNA-dependent RNA polymerase. |