CANNABIDIOL
DrugBank ID: db09061
DrugCentral: cannabidiol
Synonymous :(−)-trans-2-p-mentha-1,8-dien-3-yl-5-pentylresorcinol | (−)-trans-cannabidiol | (1’r,2’r)-5’-methyl-4-pentyl-2’-(prop-1-en-2-yl)-1’,2’,3’,4’-tetrahydrobiphenyl-2,6-diol | cannabidiol | cbd | δ1(2)-trans-cannabidiol
Drug Sentece Context
Table 1. Analysis of context sentence of cannabidiol gene in 6 abstracts.
| pmid | sentence |
|---|---|
| 32519753 | We suggest the hypothesis that Cannabidiol (CBD), a non-psychotropic phytocannabinoid, has the potential to limit the severity and progression of the disease for several reasons: 1) High-CBD Cannabis Sativa extracts are able to downregulate the expression of the two key receptors for SARS-CoV2 in several models of human epithelia 2) CBD exerts a wide range of immunomodulatory and anti-inflammatory effects and it can mitigate the uncontrolled cytokine production featuring Acute Lung Injury 3) Being a PPARγ agonist, it can display a direct antiviral activity 4) PPARγ agonists are regulators of fibroblast/myofibroblast activation and can inhibit the development of pulmonary fibrosis, thus ameliorating lung function in recovered patients. |
| 32699671 | Many cannabidiol (CBD) retailers make unsupported medical claims about their product. |
| 32804502 | This Perspective of the published essential medicinal chemistry of cannabidiol (CBD) provides evidence that the popularization of CBD-fortified or CBD-labeled health products and CBD-associated health claims lacks a rigorous scientific foundation. |
| 32923657 | Among all cannabinoids, cannabidiol (CBD) has demonstrated potent anti-inflammatory effects in a variety of pathological conditions. |
| 33001829 | There is some scientific evidence that vaping, cannabidiol (CBD - an active ingredient in cannabis from the hemp plant) or other substances, may be associated with more severe manifestations of COVID-19. |
| 33058425 | In a follow-up study to our recent findings indicating the potential of Cannabidiol (CBD) in the treatment of acute respiratory distress syndrome (ARDS), here we show for the first time that CBD may ameliorate the symptoms of ARDS through up-regulation of apelin, a peptide with significant role in the central and peripheral regulation of immunity, CNS, metabolic and cardiovascular system. |
| 33245701 | Cannabidiol can both directly and indirectly improve immunity by enhancing natural killer cell activity, reducing inflammation, and relieving stress. |
| 33267756 | However, the approval of some cannabinoids by the FDA (along with other recognized national medical health systems) has opened the horizons for the explicit use of these natural drugs in medicines such as Epidiolex® (cannabidiol used for the treatment of severe forms of epilepsy) and Sativex®(‘Δ9 -tetrahydrocannabinol and cannabidiol’ used for the treatment of spasticity caused by multiple sclerosis, aka: MS.) […] Many pharmacological properties of C. sativa are attributed to cannabidiol (CBD), a non-psychoactive component, along with Δ9 -tetrahydrocannabinol (Δ9 -THC), a psychoactive component. |
| 33323690 | Cannabis products such as cannabidiol (CBD) are being advertised for the treatment of COVID-19 associated mental health problems and substance use disorders. |
| 33363552 | Specifically, hemp contains terpenophenolic compounds such as cannabidiol (CBD) and cannabigerol (CBG), which act on cannabinoid receptors and positively regulate various human metabolic, immunological, and physiological functions. |
| 33584697 | -THC), cannabidiol (CBD), and synthetic cannabinoids; however, the mechanisms remain unclear. |