CALCITRIOL
DrugBank ID: db00136
DrugCentral: calcitriol
Synonymous :(1s,3r,5z,7e)-9,10-secocholesta-5,7,10-triene-1,3,25-triol | (1α,3β,5z,7e)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol | (5z,7e)-(1s,3r)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol | 1-alpha-25-dihydroxyvitamin d3 | 1,25-dhcc | 1,25-dihydroxycholecalciferol | 1α,25-dihydroxycholecalciferol | 1α,25-dihydroxyvitamin d3 | 1α,25(oh)2d3 | calcitriol | calcitriolum
Drug Sentece Context
Table 1. Analysis of context sentence of calcitriol gene in 6 abstracts.
| pmid | sentence |
|---|---|
| 32597823 | Although therapies selectively down-regulating both AhR and IDO1 are currently lacking, medications in clinical use such as dexamethasone may down-regulate both AhR and IDO1 genes, as calcitriol/vitamin D3 may down-regulate the AhR gene, and tocopherol/vitamin E may down-regulate the IDO1 gene. […] Supplementation of calcitriol should therefore be subjected to epidemiological studies and tested in prospective trials for prevention of CoV infections, as should tocopherol, whereas dexamethasone could be tried in interventional trials. |
| 32779213 | These properties are shared by calcitriol and the CYP11A1-generated non-calcemic hydroxyderivatives. |
| 32848776 | Initial candidate interventions include prophylaxis to augment epithelial defense (e.g., AT1 receptor blockade, type III and type I interferons, melatonin, calcitriol, camostat, and lopinavir) and to reduce viral load (e.g., remdesivir, ivermectin, emetine, Abelson kinase inhibitors, dopamine D2 antagonists, and selective estrogen receptor modulators). |
| 33194123 | D or calcitriol; IU- International Units; Interferons stimulated genes- ISG; ARI- acute respiratory infection; RSV- respiratory syncytial virus; RTI- Respiratory tract infections; COPD-Chronic obstructive pulmonary disease; BMI-Basal metabolic index; USA-USA. |