BEVIRIMAT


DrugBank ID: db06581
DrugCentral: bevirimat
Synonymous :bevirimat



Drug Sentece Context


Table 1. Analysis of context sentence of bevirimat gene in 1 abstracts.

pmid sentence
32764519 In vitro studies showed that 28-diethoxyphosphoryl-3-O-(3’,3’-dimethylsuccinyl)betulin (compound 3), the phosphate analog of bevirimat (betulinic acid derivative, HIV-1 maturation inhibitor), has IC50 (half maximal inhibitory concentration) equal to 0.02 μM. […] Compound 3 inhibits viral replication at a level comparable to bevirimat and is also more selective (selectivity indices = 1250 and 967, respectively). […] Compared with interactions between bevirimat (BVM) and the protein, an increased number of strong interactions between ligand 3 and the protein, generated by the phosphate group, were observed.