BENZIMIDAZOLE


DrugBank ID: db02962
DrugCentral: benzimidazole
Synonymous : None



Drug Sentece Context


Table 1. Analysis of context sentence of benzimidazole gene in 1 abstracts.

pmid sentence
32218301 Previously we developed a large variety of benzimidazole derivatives able to inhibit these viruses. […] Compounds 6, 8, 16 and 17, bearing the 5-(thio)semicarbazone and 5-hydrazone functionalities in combination with the 2-benzyl ring on the benzimidazole core structure, acted as dual inhibitors of influenza A virus and human coronavirus. […] For respiratory syncytial virus (RSV), activity is limited to the 5-thiosemicarbazone (25) and 5-hydrazone (22) compounds carrying the 2-[(benzotriazol-1/2-yl)methyl]benzimidazole scaffold. […] The herein-investigated benzimidazole-based derivatives may represent valuable hit compounds, deserving subsequent structural improvements towards more efficient antiviral agents for the treatment of pathologies caused by these human respiratory viruses.