BELATACEPT
DrugBank ID: db06681
DrugCentral: belatacept
Synonymous : None
Drug Sentece Context
Table 1. Analysis of context sentence of belatacept gene in 12 abstracts.
| pmid | sentence |
|---|---|
| 32711848 | Among our KTRs tested, those receiving belatacept had a lower likelihood of testing positive for SARS-CoV-2. |
| 32892322 | Three months posttransplant a recurrence of podocytopathy was successfully managed by plasma exchange, ivIG, and a conversion from tacrolimus to belatacept (initial proteinuria > 6 g/l decreased to 169 mg/l). |
| 33305112 | During the coronavirus disease 2019 (Covid-19) pandemic, several physicians have questioned pursuing belatacept in kidney-transplant patients in order to reduce the risk of nosocomial transmission during the monthly infusion. […] The effect of the conversion from belatacept to another immunosuppressive regimen is underreported. […] The aim of the present retrospective study was to assess the effect on kidney function and the clinical outcome of the conversion from belatacept to another regimen. […] We have identified 44 maintenance kidney transplantation patients from five French kidney transplantation centers who were converted from belatacept to another regimen either because of a complication (n = 28) or another reason (patients’ request or belatacept shortage, n = 13). […] The follow-up after the conversion from belatacept was 27.5 ± 25.3 months. […] = 0.0002). eGFR significantly decreased in patients who had been given belatacept at transplantation as well as in those who had been converted to belatacept earlier. […] The decrease was less significant in patients who had stopped belatacept without having experienced any complications. […] Thus, transplantation physicians should avoid stopping belatacept when not clinically required. |