ASPARAGINE
DrugBank ID: db00174
DrugCentral: asparagine
Synonymous :(2s)-2-amino-3-carbamoylpropanoic acid | (2s)-2,4-diamino-4-oxobutanoic acid | (s)-2-amino-3-carbamoylpropanoic acid | (s)-asparagine | 2-aminosuccinamic acid | alpha-aminosuccinamic acid | asn | asparagine | aspartamic acid | l-2-aminosuccinamic acid | l-asparagine | l-aspartic acid beta-amide | l-aspartic acid β-amide | α-aminosuccinamic acid
Drug Sentece Context
Table 1. Analysis of context sentence of asparagine gene in 7 abstracts.
pmid | sentence |
---|---|
32493627 | The presence of glutamine, asparagine, leucine, phenylalanine and serine amino acids in SARS-CoV-2 enhances ACE2 binding. |
32679775 | The spontaneous conversion of asparagine (Asn) residues to aspartic acid or isoaspartic acid is a frequent modification in proteins as part of the process called deamidation. |
32753553 | By using deep mutagenesis, mutations in ACE2 that increase S binding are found across the interaction surface, in the asparagine 90-glycosylation motif and at buried sites. |
32979815 | The relative binding poses of Z93 fitted well in the binding site of both proteases and showed consensus π-π stacking and H-bond interactions with histidine and aspartate/asparagine residues of the catalytic triad. |
33578036 | Using this bioreporter, we uncovered critical host and viral determinants of the interaction, including a role for glycosylation of asparagine residues within the RBD in mediating successful viral entry. |
33587268 | One prominent adaptive mutation is the asparagine-to-glycine substitution at amino acid position 614 in the viral spike protein (D614G), which has become dominant in the currently circulating virus strains. |