ARTESUNATE


DrugBank ID: db09274
DrugCentral: artesunate
Synonymous :artesunate | artesunato | artesunatum | artesunic acid | as | butanedioic acid, 1-[(3r,5as,6r,8as,9r,10s,12r,12ar)-decahydro-3,6,9-trimethyl-3,12-epoxy-12h-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester | dihydroqinghasu hemsuccinate



Drug Sentece Context


Table 1. Analysis of context sentence of artesunate gene in 3 abstracts.

pmid sentence
32514287 Artesunate is a semisynthetic derivative of artemisinin, an antimalarial drug. […] Artesunate was thought to be an effective treatment for covid-19 because of its anti-inflammatory activity, NF-κB (nuclear Factor kappa B)-coronavirus effect and chloroquine-like endocytosis inhibition mechanism.
32527344 To discuss the effective of artesunate in the treatment of coronavirus disease 2019 (COVID-19). […] Using prospective method, the 43 cases of confirmed COVID-19 patients in Nanning Fourth People’s Hospital from January 22nd to February 15th in 2020 were enrolled and divided into routine treatment group (n = 25) and artesunate treatment group (n = 18) by odd-even rule after admission. […] According to the guidelines, the routine treatment group was recommended to receive lopinavir/ritonavir 500 mg + α-aerosolized interferon 500×104 U, twice daily; the artesunate treatment group was given artesunate 60 mg, twice daily besides the routine treatment, for 10 days in both groups. […] In artesunate treatment group, the time for significant improvement of symptoms (days: 3.33±1.91 vs. […] Artesunate can shorten the treatment time of COVID-19, improve prognosis and eliminate pathogens, with fewer adverse reactions and a good application prospect.