APROTININ


DrugBank ID: db06692
DrugCentral: aprotinin
Synonymous :aprotinin (bovine) | aprotinin biosynthetic | aprotinin bovine | aprotinin concentrated solution | aprotinina | bovine aprotinin | bovine pancreatic trypsin inhibitor | bpti | fibrinolysis inhibitor | trypsin inhibitor, pancreatic basic



Drug Sentece Context


Table 1. Analysis of context sentence of aprotinin gene in 4 abstracts.

pmid sentence
32534506 Thereby, we speculated that inhibition of bradykinin synthesis and/or blockade of bradykinin B2 receptor using Aprotinin/ecallantide and Icatibant, respectively, may hold therapeutic promise in severe cases and these molecules can be advanced to clinical trials.
32537610 Aprotinin is a nonspecific protease inhibitor especially of trypsin, chymotrypsin, plasmin, and kallikrein, and it is many years in clinical use. […] Aprotinin inhibits the release of pro-inflammatory cytokines and involved in the process of glycoprotein homeostasis. […] Experimental data support that the use of aprotinin to inhibit MMPs and KKS may be a new potential approach to the treatment of ALI / ARDS.
32972339 Both available evidence as well as hypotheses are discussed, with emphasis on drugs which are approved for other indications such as bromhexine, ammonium chloride, nafamostat, camostat, tranexamic acid, epsilon amino-caproic acid, chloroquine, ulinastatin, aprotinin and anticoagulant drugs.