AMOXICILLIN


DrugBank ID: db01060
DrugCentral: amoxicillin
Synonymous :(2s,5r,6r)-6-{[(2r)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid | 6-(p-hydroxy-α-aminophenylacetamido)penicillanic acid | amox | amoxicilina | amoxicillin | amoxicillin (anhydrous) | amoxicillin anhydrous | amoxicilline | amoxicillinum | amoxycillin | ax | p-hydroxyampicillin | α-amino-p-hydroxybenzylpenicillin



Drug Sentece Context


Table 1. Analysis of context sentence of amoxicillin gene in 5 abstracts.

pmid sentence
32327397 Queries extracted reports based on exposures of HCQ/chloroquine (CQ) alone, azithromycin alone, HCQ/CQ + azithromycin, amoxicillin alone, HCQ/CQ + amoxicillin alone. […] Amoxicillin served as a control. […] For the control of amoxicillin, there were no safety signals when used alone or in combination with HCQ/CQ.
32392007 Amoxicillin is first choice treatment for respiratory infections during the COVID-19 epidemic; there is lack of evidence to support azithromycin as a first choice.Respiratory rate > 24 / min or saturation <92-94% indicate imminent respiratory decompensation and may be reasons for referral.
32409150 We compared risk of cardiac adverse events between combinations of chloroquine and azithromycin and chloroquine and amoxicillin. […] We included autoimmune disease patients aged ≥18 years initiating azithromycin or amoxicillin for ≥5 days during chloroquine treatment. […] The adjusted incidence of cardiac symptoms among azithromycin and amoxicillin users was 276 vs 254 per 10,000 person-years with an adjusted HR of 1.10 (95%CI, 0.62-1.95).
32485652 We included the widely used antibiotic, amoxicillin, for comparison. […] Our findings indicate that α-ketoamide 13b binds more tightly (predicted GlideScore = -8.7 and -9.2 kcal/mol for protomers A and B, respectively), to the protease active site compared to amoxicillin (-5.0 and -4.8 kcal/mol). […] In contrast, amoxicillin interacts unfavourably with the protease (ΔG = +32.8 kcal/mol for protomer A), with unbinding events observed in several independent simulations.
32538597 For children three months to three years of age, azithromycin or amoxicillin is recommended if pneumonia is suspected; for urinary infections, suggested antibiotics are cefixime, amoxicillin/clavulanate, or trimethoprim/sulfamethoxazole.