AMODIAQUINE


DrugBank ID: db00613
DrugCentral: amodiaquine
Synonymous :amodiaquina | amodiaquine | amodiaquinum



Drug Sentece Context


Table 1. Analysis of context sentence of amodiaquine gene in 9 abstracts.

pmid sentence
32395606 Out of 62 screened compounds, the best docking scores with the targets were found for compounds: lopinavir, amodiaquine, and theaflavin digallate (TFDG).
32486229 In this study, the bioactivity of some selected heterocyclic drugs named Favipiravir (1), Amodiaquine (2), 2’-Fluoro-2’-deoxycytidine (3), and Ribavirin (4) was evaluated as inhibitors and nucleotide analogues for COVID-19 using computational modeling strategies. […] Besides, the computations data of DFT the docking simulation studies was predicted that the Amodiaquine (2) has the least binding energy (-7.77 Kcal/mol) and might serve as a good inhibitor to SARS-CoV-2 comparable with the approved medicines, hydroxychloroquine, and remdesivir which have binding affinity -6.06 and -4.96 Kcal/mol, respectively.
32545799 We also screened 136 safe-in-man broad-spectrum antivirals against the SARS-CoV-2 infection in Vero-E6 cells and identified nelfinavir, salinomycin, amodiaquine, obatoclax, emetine and homoharringtonine. […] We found that a combination of orally available virus-directed nelfinavir and host-directed amodiaquine exhibited the highest synergy.