Drug Sentece Context
Table 1. Analysis of context sentence of almond gene in 5 abstracts.
|32963884||Of the 65 compounds, only three, namely, 3-galloylcatechin, proanthocyanidin B1, and luteolin 7-galactoside found in almond (Terminalia catappa), grape (Vitis vinifera), and common verbena (Verbena officinalis), were able to bind to all eight targets better than the reported repurposed drugs.|
|33292385||Among them, ephedra-bitter almond is a common couplet medicine in anti-COVID-19 prescriptions. […] This study aims to conduct an exploration of key components and mechanisms of ephedra-bitter almond anti-COVID-19 based on network pharmacology. […] We collected and screened potential active components of ephedra-bitter almond based on the TCMSP Database, and we predicted targets of the components. […] Then, the potential targets of ephedra-bitter almond against COVID-19 were screened out. […] The key components, targets, biological processes, and pathways of ephedra-bitter almond anti-COVID-19 were predicted by constructing the relationship network of herb-component-target (H-C-T), protein-protein interaction (PPI), and functional enrichment. […] Ephedra-bitter almond played an overall regulatory role in anti-COVID-19 via the patterns of multi-component-target-pathway. […] In addition, some key components of ephedra-bitter almond, such as β-sitosterol, estrone, and stigmasterol, had high binding activity to 3CL and ACE2 by molecular docking simulation, which provided new molecular structures for new drug development of COVID-19.|