ALEMTUZUMAB


DrugBank ID: db00087
DrugCentral: alemtuzumab
Synonymous : None



Drug Sentece Context


Table 1. Analysis of context sentence of alemtuzumab gene in 3 abstracts.

pmid sentence
32477373 As lymphopenia seems to be associated with a more severe disease course, all DMTs causing lymphopenia, such as cladribine, alemtuzumab, and dimethyl fumarate, need to be reviewed more thoroughly.
32554284 Alemtuzumab is an immunosuppressive drug that induces lymphocytes depletion. […] In this study, we aimed to evaluate the frequency and severity of COVID-19 in a case series of patients treated with alemtuzumab in our center. […] Mean time from the last dose of Alemtuzumab was 9.80 ± 6.64 months, and last lymphocyte count was 760 ± 231 / μL. […] Conversely, we did not find statistically significant differences regarding age, EDSS, last lymphocyte count, and months since the last dose of alemtuzumab administered between patients having or not symptoms of COVID-19. […] Our data suggest that patients receiving alemtuzumab showed very mild symptoms of COVID-19. […] Further research about alemtuzumab and their role in COVID-infection is necessary to confirm these preliminary findings.