ACETAMINOPHEN

Drug Sentece Context

Table 1. Analysis of context sentence of acetaminophen gene in 28 abstracts.

pmid	sentence
32293020	Based on the evidence to date, there are several treatment options to consider for the relief of fever (acetaminophen, NSAID, oral glucocorticoids), cough (morphine), breathlessness (morphine, oxygen, fan), anxiety (benzodiazepines) and pain (NSAID, morphine).
32303650	The first patient was treated with intravenous immunoglobulin and the second, with acetaminophen.
32404451	Ibuprofen or acetaminophen for fever and pain can be given.
32447629	Paracetamol (acetaminophen) has been proposed as an alternative to NSAIDs but there are issues with liver toxicity at high doses.
32460369	Although based on existing evidence, NSAIDs have been effective in treating respiratory infections caused by influenza and rhinovirus, since there is no clinical trial on COVID-19 and case-reports and clinical experiences are indicative of elongation of treatment duration and exacerbation of the clinical course of patients with COVID-19, it is recommended to use substitutes such as acetaminophen for controlling fever and inflammation and be cautious about using NSAIDs in management of COVID-19 patients until there are enough evidence.
32474064	Additionally, acetylsalicylic acid (ASA) and acetaminophen (APAP) were discovered alleviating NETs formation.
32505846	Over the counter antipyretics such as ibuprofen and acetaminophen are often taken by individuals to reduce the discomfort of fever. […] Studies show that ibuprofen demonstrates superior efficacy in fever reduction compared to acetaminophen.
32526083	During the hospitalization, 86 patients developed de novo LFTs abnormality, which was associated with the use of tocilizumab, lopinavir/ritonavir and acetaminophen and not clearly associated with the composite endpoint.
32779108	The patient was given acetaminophen, NSAIDs, and opioids with no relief of pain.
32779108	The patient was given acetaminophen, NSAIDs, and opioids with no relief of pain.
32779108	The patient was given acetaminophen, NSAIDs, and opioids with no relief of pain.
32779108	The patient was given acetaminophen, NSAIDs, and opioids with no relief of pain.
32779108	The patient was given acetaminophen, NSAIDs, and opioids with no relief of pain.
32779108	The patient was given acetaminophen, NSAIDs, and opioids with no relief of pain.
32779108	The patient was given acetaminophen, NSAIDs, and opioids with no relief of pain.
32779108	The patient was given acetaminophen, NSAIDs, and opioids with no relief of pain.
32808185	Within the analgesics, acetaminophen revealed a dose-dependent reduction in expression of ACE2, while non-steroidal anti-inflammatory drugs had mixed effect on receptors expression.
32866247	Significantly more providers reported increasing rather than decreasing prescriptions of the following medications: opioids (28.8% vs 6.2% of providers, P < 0.001), muscle relaxants (22.3% vs 5.4%, P < 0.001), neuropathic pain medications (29.6% vs 3.8%, P < 0.001), and acetaminophen (26.2% vs 4.2%, P < 0.001).
33006138	Additionally, the data for the use of acetylcysteine to manage non-acetaminophen-induced ALF is limited.
33017864	We describe the case of an orthotopic liver transplantation (OLT) in a young female who presented with acute liver failure secondary to acetaminophen toxicity to manage abdominal pain and in the setting of a positive SARS-CoV2 test.
33090438	Haptoglobin, hemopexin, heme oxygenase-1 and acetaminophen may be used to maintain the integrity of the RBC membrane.
33098875	Present study was therefore, conducted to generate data on self-medication practice with analgesics using non-steroidal anti-inflammatory drugs (NSAIDs) and acetaminophen, and the antibiotics among nursing students of University College Farasan Campus. […] Acetaminophen was highest used drug for analgesic purposes without prescriptions (n=101 participants, 57%).
33217260	We believe the patient’s condition was precipitated by a COVID-19 infection-induced delirium, a setting in which he ingested aspirin and acetaminophen in overdose that required lifesaving interventions.
33235800	She was given isotonic saline and acetaminophen and prescribed azithromycin and acetaminophen and sent home for isolation. […] SARS-CoV-2 PCR was reported positive and she was prescribed hydroxychloroquine, acetaminophen and sent home for isolation again.
33310574	During lockdown, changes in the consumption patterns of recreational drugs (i.e. cocaine, amphetamine, 3,4-methylenedioxymethamphetamine, methamphetamine, and alcohol) and pharmaceuticals for short-term application (i.e. acetaminophen, codeine, and trimethoprim) were detected.
33350580	Acetaminophen (APAP) is one of the few recommended analgesic and antipyretic drugs in some critical cases such as viral disease COVID-19.
33375616	Several well-studied drugs can downregulate the expression of TMPRSS2 in human cells, including acetaminophen (paracetamol) and curcumin.
33519270	The majority of respondents self-medicated with acetaminophen for respiratory symptoms and mainly because they had a cold or flu. […] It was observed that all the surveyed drugs (acetaminophen, ibuprofen, azithromycin, penicillin, antiretrovirals and hydroxychloroquine) were consumed for various symptoms including: fever, fatigue, cough, sneezing, muscle pain, nasal congestion, sore throat, headache and breathing difficulty. […] Multivariable logistic regression showed that older people have a higher frequency of antiretroviral self-medication, respondents who currently have a job had a higher frequency of penicillin self-medication, and that respondents from the Andes consumed less acetaminophen, while the ones from the rainforest consumed it more.